Detailed information for compound 1398887

Basic information

Technical information
  • TDR Targets ID: 1398887
  • Name: 3-[2-(2,5-dimethoxyphenyl)-2-oxoethyl]-3-hydr oxy-1-[(2-methylphenyl)methyl]indol-2-one
  • MW: 431.48 | Formula: C26H25NO5
  • H donors: 1 H acceptors: 3 LogP: 3.89 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(c(c1)C(=O)CC1(O)C(=O)N(c2c1cccc2)Cc1ccccc1C)OC
  • InChi: 1S/C26H25NO5/c1-17-8-4-5-9-18(17)16-27-22-11-7-6-10-21(22)26(30,25(27)29)15-23(28)20-14-19(31-2)12-13-24(20)32-3/h4-14,30H,15-16H2,1-3H3
  • InChiKey: XOAQCBGVNSMZPI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[2-(2,5-dimethoxyphenyl)-2-oxo-ethyl]-3-hydroxy-1-[(2-methylphenyl)methyl]indolin-2-one
  • 3-[2-(2,5-dimethoxyphenyl)-2-oxoethyl]-3-hydroxy-1-[(2-methylphenyl)methyl]-2-indolinone
  • 3-[2-(2,5-dimethoxyphenyl)-2-keto-ethyl]-3-hydroxy-1-(2-methylbenzyl)oxindole
  • 3-[2-(2,5-dimethoxyphenyl)-2-oxo-ethyl]-3-hydroxy-1-[(2-methylphenyl)methyl]indol-2-one
  • STK214385
  • BAS 05329826
  • NCGC00100222-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens mechanistic target of rapamycin (serine/threonine kinase) Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Equus caballus Ferritin light chain Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus FKBP12 rapamycin complex associated protein Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum ko:K07203 FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans frameshifted from upstream TOR2 CDS (CaP19.1905) Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Leishmania infantum target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma congolense Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei gambiense phosphatidylinositol 3-kinase tor, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania donovani Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major target of rapamycin (TOR) kinase 1, putative Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania donovani Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei phosphatidylinositol 4-kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Candida albicans similar to N terminal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) putative protein/phosphatidylinositol kinases in Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis FKBP12 rapamycin complex associated protein Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans frameshifted from upsteam TOR2 CDS (CaP19.9461) Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania braziliensis target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania infantum target of rapamycin (TOR) kinase 1, putative Get druggable targets OG5_127212 All targets in OG5_127212
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to N terminal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) putative protein/phosphatidylinositol kinases in Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma brucei gambiense phosphatidylinositol 3 kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to internal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) protein/phosphatidylinositol kinases involved in n Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania mexicana phosphatidylinositol 3-kinase (tor2)-like protein Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) phosphatidylinositol 3 Get druggable targets OG5_127212 All targets in OG5_127212
Giardia lamblia GTOR Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma congolense Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to internal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) protein/phosphatidylinositol kinases involved in n Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Toxoplasma gondii target of rapamycin (TOR), putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania mexicana phosphatidylinositol 3 kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein Get druggable targets OG5_127212 All targets in OG5_127212
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Neospora caninum Phosphatidylinositol 3-kinase tor2, related Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis expressed protein Ferritin light chain   175 aa 146 aa 30.1 %
Schistosoma japonicum Ferritin, putative Ferritin light chain   175 aa 144 aa 24.3 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 146 aa 28.8 %
Echinococcus granulosus expressed protein Ferritin light chain   175 aa 146 aa 28.8 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 44.4 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 142 aa 29.6 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 43.9 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0536 0.0536
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0536 0.1579
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0054 0.3246 1
Brugia malayi TAR-binding protein 0.0076 0.4916 0.4628
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.1367 0.4161
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.2201 0.6753
Schistosoma mansoni tar DNA-binding protein 0.0076 0.4916 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.1371 0.4171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.265 0.8147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.3246 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.3246 0.3246
Schistosoma mansoni tar DNA-binding protein 0.0076 0.4916 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0043 0.2415 0.6934
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0054 0.3246 0.6187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0536 0.1579
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.1605 0.4901
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.1904 0.5829
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.2201 0.6753
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0054 0.3246 0.6187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.2412 0.7408
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.2201 0.6753
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.2412 0.7408
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0043 0.2415 0.6934
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.1367 0.4161
Schistosoma mansoni tar DNA-binding protein 0.0076 0.4916 1
Loa Loa (eye worm) TAR-binding protein 0.0076 0.4916 0.4916
Schistosoma mansoni tar DNA-binding protein 0.0076 0.4916 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0054 0.3246 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0043 0.2415 0.6934
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.2412 0.7408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.1605 0.4901
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0536 0.1579
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.2201 0.6753
Loa Loa (eye worm) hypothetical protein 0.0011 0.0028 0.0028
Loa Loa (eye worm) RNA binding protein 0.0076 0.4916 0.4916
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.3246 0.2863
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.1371 0.4171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0536 0.1579
Giardia lamblia GTOR 0.0054 0.3246 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0263 0.0729
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.1605 0.4901
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0054 0.3246 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.2412 0.7408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.1367 0.4161
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.4916 0.4916
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.1581 0.4826
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0026 0.1097 0.207
Schistosoma mansoni tar DNA-binding protein 0.0076 0.4916 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.1371 0.4171
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0054 0.3246 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0536 0.1579
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.2201 0.6753
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.4916 0.4628
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.2412 0.7408
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0054 0.3246 0.6187
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0054 0.3246 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.1371 0.4171
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0054 0.3246 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.004 0.2201 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.2201 0.6753
Brugia malayi RNA binding protein 0.0076 0.4916 0.4628
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.1581 0.4826
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.3246 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.2201 0.6753
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0023 0.0863 0.1204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.1816 0.5555
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.3246 1
Echinococcus multilocularis tar DNA binding protein 0.0076 0.4916 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0054 0.3246 1
Echinococcus granulosus tar DNA binding protein 0.0076 0.4916 1
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0054 0.3246 1

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 2.6122 uM PubChem BioAssay. Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Hit Validation. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.8479 uM PubChem BioAssay. Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in WT MEF Cells: Hit Validation. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 10.3992 uM PUBCHEM_BIOASSAY: Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2660, AID2666, AID2667, AID2668, AID2681, AID504465] ChEMBL. No reference
Potency (functional) 13.0918 uM PUBCHEM_BIOASSAY: IN Cell qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2660, AID2666, AID2667, AID2668, AID2681, AID493208] ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference
Potency (functional) 89.1251 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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