Detailed information for compound 1430398

Basic information

Technical information
  • TDR Targets ID: 1430398
  • Name: methyl 3-amino-2-cyano-5-(3-methoxyphenyl)-7- methyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-ca rboxylate
  • MW: 356.399 | Formula: C17H16N4O3S
  • H donors: 1 H acceptors: 2 LogP: 2.14 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C1=C(C)N=c2n(C1c1cccc(c1)OC)c(N)c(s2)C#N
  • InChi: 1S/C17H16N4O3S/c1-9-13(16(22)24-3)14(10-5-4-6-11(7-10)23-2)21-15(19)12(8-18)25-17(21)20-9/h4-7,14H,19H2,1-3H3
  • InChiKey: ZQVHNYQRPHHVCI-UHFFFAOYSA-N  

Network

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Synonyms

  • methyl 3-amino-2-cyano-5-(3-methoxyphenyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate
  • 3-amino-2-cyano-5-(3-methoxyphenyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid methyl ester
  • SMR000161317
  • AO-476/43201327
  • MLS000537201

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.017 0.0126
Schistosoma mansoni hypothetical protein 0.0019 0.017 0.017
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0043 0.0464 0.5
Brugia malayi RE18450p 0.0043 0.0464 0.6617
Schistosoma mansoni hypothetical protein 0.0041 0.0437 0.0437
Brugia malayi pyruvate dehydrogenase phosphatase regulatory subunit precursor 0.0043 0.0464 0.6617
Chlamydia trachomatis D-amino acid dehydrogenase 0.0043 0.0464 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0035 0.5
Mycobacterium leprae PROBABLE D-AMINO ACID OXIDASE AAO 0.0521 0.6228 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.017 0.0163
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.017 0.1704
Loa Loa (eye worm) hypothetical protein 0.0521 0.6228 1
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0035 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0035 0.5
Schistosoma mansoni d-amino acid oxidase 0.0521 0.6228 0.6228
Schistosoma mansoni fad oxidoreductase 0.0043 0.0464 0.0464
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0825 0.0689
Trypanosoma brucei L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0043 0.0464 0.5
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0607 0.9
Echinococcus multilocularis GPCR, family 2 0.0019 0.017 0.0126
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0607 0.0565
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial 0.0043 0.0464 0.5
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0035 0.5
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0043 0.0464 0.5
Echinococcus granulosus glycerol 3 phosphate dehydrogenase 0.0043 0.0464 0.0422
Echinococcus granulosus cpg binding protein 0.0037 0.0382 0.034
Schistosoma mansoni hypothetical protein 0.0019 0.017 0.017
Trypanosoma cruzi FAD dependent oxidoreductase, putative 0.0043 0.0464 0.5
Schistosoma mansoni hypothetical protein 0.0019 0.017 0.017
Schistosoma mansoni fad oxidoreductase 0.0043 0.0464 0.0464
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0069 0.0026
Echinococcus multilocularis glycerol 3 phosphate dehydrogenase 0.0043 0.0464 0.0422
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0641
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0667 1
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase, putative 0.0043 0.0464 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0607 0.0565
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0035 0.5
Schistosoma mansoni NAD dehydrogenase 0.0043 0.0464 0.0464
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0607 0.0607
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.017 0.0126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0035 0.5
Schistosoma mansoni cpg binding protein 0.0035 0.0359 0.0359
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0043 0.0464 0.5
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0667 0.097
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.017 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0035 0.5
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0825 0.0626
Echinococcus granulosus dnaJ subfamily B 0.0494 0.5903 0.5885
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0828 0.0828
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0035 0.5
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0641
Schistosoma mansoni glycerol-3-phosphate dehydrogenase 0.0043 0.0464 0.0464
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.017 0.0163
Schistosoma mansoni hypothetical protein 0.0019 0.017 0.017
Echinococcus granulosus FAD dependent oxidoreductase domain containing protein 0.0043 0.0464 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0035 0.5
Trypanosoma brucei electron transfer flavoprotein-ubiquinone oxidoreductase, putative 0.0043 0.0464 0.5
Loa Loa (eye worm) hypothetical protein 0.0043 0.0464 0.0641
Onchocerca volvulus Dimethylglycine dehydrogenase, mitochondrial homolog 0.0043 0.0464 1
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0035 0.5
Entamoeba histolytica anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative 0.0043 0.0464 0.5
Onchocerca volvulus Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial homolog 0.0043 0.0464 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0825 0.0785
Echinococcus granulosus GPCR family 2 0.0019 0.017 0.0126
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0359 0.0469
Brugia malayi CXXC zinc finger family protein 0.0035 0.0359 0.4856
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0069 0.0026
Plasmodium vivax FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0043 0.0464 0.5
Mycobacterium ulcerans D-amino acid oxidase Aao 0.0521 0.6228 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0607 0.0872
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0825 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0733 0.7452
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0607 0.0565
Plasmodium falciparum FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0043 0.0464 0.5
Brugia malayi Latrophilin receptor protein 2 0.0019 0.017 0.1704
Echinococcus multilocularis cpg binding protein 0.0037 0.0382 0.034
Mycobacterium tuberculosis Probable D-amino acid oxidase Aao 0.0477 0.5704 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0607 0.0565
Echinococcus multilocularis microtubule associated protein 2 0.0833 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0607 0.0607
Onchocerca volvulus Putative fad oxidoreductase 0.0043 0.0464 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0035 0.5
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0043 0.0464 0.5
Trypanosoma brucei FAD dependent oxidoreductase, putative 0.0043 0.0464 0.5
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0035 0.5
Schistosoma mansoni cpg binding protein 0.0037 0.0382 0.0382
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0825 0.0825
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0035 0.5
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0825 0.0626
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0667 1
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0825 1
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0437 0.616
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0043 0.0464 0.5
Echinococcus multilocularis FAD dependent oxidoreductase domain containing protein 0.0043 0.0464 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0035 0.5
Schistosoma mansoni hypothetical protein 0.0494 0.5903 0.5903
Schistosoma mansoni microtubule-associated protein tau 0.0833 1 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0667 0.097
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0607 0.0607
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0043 0.0464 0.5
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0035 0.5
Schistosoma mansoni ATP:guanidino kinase (Smc74) 0.0043 0.0464 0.0464
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0035 0.5
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0825 0.0785
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0035 0.5
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.017 0.0126
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0044 0.0044
Schistosoma mansoni cpg binding protein 0.0037 0.0382 0.0382
Trichomonas vaginalis helicase, putative 0.0008 0.0035 0.5
Brugia malayi cDNA sequence BC016226 0.0043 0.0464 0.6617
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 20 0.0043 0.0464 0.5
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0825 0.0825
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.5903 0.5885
Loa Loa (eye worm) hypothetical protein 0.0041 0.0437 0.0596
Loa Loa (eye worm) glycerol-3-phosphate dehydrogenase 0.0043 0.0464 0.0641
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0825 0.0626
Brugia malayi dimethylglycine dehydrogenase, mitochondrial precursor, putative 0.0043 0.0464 0.6617
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0043 0.0464 0.5

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) > 112.219 um PUBCHEM_BIOASSAY: Luminescence Biochemical Dose Response HTS to Identify Inhibitors of Luciferase. (Class of assay: confirmatory) [Related pubchem assays: 1663 (Primary HTS), 1678 (Summary of Project)] ChEMBL. No reference
EC50 (binding) > 300 um PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Identify Inhibitors of Mex-5 Binding to TCR-2. (Class of assay: confirmatory) [Related pubchem assays: 1833 (Project Summary), 1832 (Primary HTS)] ChEMBL. No reference
EC50 (binding) > 300 um PUBCHEM_BIOASSAY: Fluorescent Polarization Homogeneous Dose Response HTS to Identify Inhibitors of POS-1 Binding to mex-3-RNA. (Class of assay: confirmatory) [Related pubchem assays: 1833 (Project Summary), 1832 (Primary HTS)] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (binding) = 19.9526 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 23.1093 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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