Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | lamin | 0.0056 | 0.0175 | 0.0325 |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.0042 | 0.0078 |
Echinococcus multilocularis | lactate dehydrogenase protein | 0.0549 | 0.3471 | 0.3471 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0059 | 0.0191 | 0.0191 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.0191 | 0.0269 |
Plasmodium vivax | malate dehydrogenase, putative | 0.0549 | 0.3471 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0059 | 0.0191 | 0.0551 |
Loa Loa (eye worm) | malate dehydrogenase | 0.0256 | 0.1507 | 0.2071 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0834 | 0.5382 | 1 |
Echinococcus granulosus | cytosolic malate dehydrogenase | 0.0263 | 0.1555 | 0.1555 |
Mycobacterium tuberculosis | Probable malate dehydrogenase Mdh | 0.0263 | 0.1555 | 0.5734 |
Echinococcus multilocularis | carbonic anhydrase | 0.0452 | 0.2821 | 0.2821 |
Toxoplasma gondii | lactate dehydrogenase LDH2 | 0.0549 | 0.3471 | 1 |
Entamoeba histolytica | malate dehydrogenase, putative | 0.0263 | 0.1555 | 0.448 |
Echinococcus multilocularis | carbonic anhydrase | 0.0452 | 0.2821 | 0.2821 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0282 | 0.034 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0156 | 0.0841 | 0.1562 |
Plasmodium vivax | lactate/malate dehydrogenase, putative | 0.0237 | 0.138 | 0.3976 |
Brugia malayi | AMP-binding enzyme family protein | 0.0097 | 0.0447 | 0.0628 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0097 | 0.0447 | 0.0685 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0084 | 0.0356 | 0.1191 |
Leishmania major | cathepsin L-like protease | 0.0059 | 0.0191 | 0.0279 |
Plasmodium falciparum | glutathione reductase | 0.0037 | 0.0042 | 0.0121 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0841 | 0.1496 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0097 | 0.0447 | 0.0685 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0136 | 0.071 | 0.132 |
Mycobacterium leprae | PROBABLE MALATE DEHYDROGENASE MDH | 0.0263 | 0.1555 | 0.5157 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0834 | 0.5382 | 0.7549 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0237 | 0.138 | 0.8876 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0059 | 0.0191 | 0.0211 |
Echinococcus granulosus | malate dehydrogenase | 0.0256 | 0.1507 | 0.1507 |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0354 | 0.2164 | 0.3 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0039 | 0.0061 | 0.0086 |
Brugia malayi | AMP-binding enzyme family protein | 0.0097 | 0.0447 | 0.0628 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0452 | 0.2821 | 0.3965 |
Echinococcus granulosus | lamin dm0 | 0.0056 | 0.0175 | 0.0175 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Echinococcus multilocularis | lamin | 0.0056 | 0.0175 | 0.0175 |
Leishmania major | cathepsin L-like protease | 0.0059 | 0.0191 | 0.0279 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0084 | 0.0356 | 0.1191 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0056 | 0.0175 | 0.0246 |
Trypanosoma cruzi | cytosolic malate dehydrogenase, putative | 0.0263 | 0.1555 | 0.2889 |
Mycobacterium leprae | PROBABLE HYDROLASE | 0.0431 | 0.268 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0084 | 0.0356 | 0.1191 |
Schistosoma mansoni | L-lactate dehydrogenase | 0.0237 | 0.138 | 0.2564 |
Echinococcus granulosus | lactate dehydrogenase a | 0.0549 | 0.3471 | 0.3471 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0037 | 0.0042 | 0.0121 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0073 | 0.0282 | 0.0814 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0059 | 0.0191 | 0.0269 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.0191 | 0.0269 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0084 | 0.0356 | 0.1191 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0061 | 0.0026 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Plasmodium vivax | glutathione reductase, putative | 0.0037 | 0.0042 | 0.0121 |
Wolbachia endosymbiont of Brugia malayi | malate dehydrogenase | 0.0549 | 0.3471 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0059 | 0.0191 | 0.0551 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Onchocerca volvulus | Matrilysin homolog | 0.1023 | 0.6643 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.0191 | 0.0269 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0093 | 0.0419 | 0.1428 |
Mycobacterium tuberculosis | Probable reductase | 0.0084 | 0.0356 | 0.1191 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0785 | 0.5048 | 0.7577 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0093 | 0.0419 | 0.1428 |
Toxoplasma gondii | hypothetical protein | 0.0452 | 0.2821 | 0.8106 |
Leishmania major | glycosomal malate dehydrogenase | 0.0256 | 0.1507 | 0.2744 |
Onchocerca volvulus | Cathepsin F homolog | 0.0059 | 0.0191 | 0.0198 |
Echinococcus granulosus | cathepsin l1 | 0.0039 | 0.0061 | 0.0061 |
Echinococcus granulosus | carbonic anhydrase | 0.0452 | 0.2821 | 0.2821 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0097 | 0.0447 | 0.0685 |
Schistosoma mansoni | lamin | 0.0056 | 0.0175 | 0.0325 |
Onchocerca volvulus | 0.0059 | 0.0191 | 0.0198 | |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.0191 | 0.0269 |
Entamoeba histolytica | malate dehydrogenase,cytoplasmic, putative | 0.0263 | 0.1555 | 0.448 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0037 | 0.0045 | 0.0045 |
Mycobacterium tuberculosis | Probable peptidoglycan hydrolase | 0.0431 | 0.268 | 1 |
Plasmodium falciparum | L-lactate dehydrogenase | 0.0549 | 0.3471 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0059 | 0.0191 | 0.0191 |
Echinococcus granulosus | lactate dehydrogenase protein | 0.0549 | 0.3471 | 0.3471 |
Plasmodium vivax | vivapain-2 | 0.0059 | 0.0191 | 0.0551 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0039 | 0.0061 | 0.0175 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0073 | 0.0282 | 0.0911 |
Schistosoma mansoni | L-lactate dehydrogenase | 0.0549 | 0.3471 | 0.6449 |
Echinococcus multilocularis | malate dehydrogenase | 0.0256 | 0.1507 | 0.1507 |
Brugia malayi | Cathepsin L-like precursor | 0.0039 | 0.0061 | 0.0086 |
Trypanosoma cruzi | malate dehydrogenase, putative | 0.0256 | 0.1507 | 0.28 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0282 | 0.034 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0841 | 0.1496 |
Echinococcus granulosus | cytosolic malate dehydrogenase | 0.0263 | 0.1555 | 0.1555 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0039 | 0.0061 | 0.0113 |
Echinococcus granulosus | malate dehydrogenase | 0.0256 | 0.1507 | 0.1507 |
Brugia malayi | glutathione reductase | 0.0037 | 0.0042 | 0.0059 |
Brugia malayi | Hemopexin family protein | 0.0502 | 0.3154 | 0.4432 |
Echinococcus multilocularis | cytosolic malate dehydrogenase | 0.0263 | 0.1555 | 0.1555 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.0042 | 0.0078 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0097 | 0.0447 | 0.0685 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0097 | 0.0447 | 0.1287 |
Echinococcus granulosus | carbonic anhydrase | 0.0452 | 0.2821 | 0.2821 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0097 | 0.0447 | 0.0685 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.0061 | 0.0391 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0115 | 0.0568 | 0.3654 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Echinococcus multilocularis | L lactate dehydrogenase B chain | 0.0549 | 0.3471 | 0.3471 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Echinococcus multilocularis | cytosolic malate dehydrogenase | 0.0263 | 0.1555 | 0.1555 |
Leishmania major | cysteine peptidase A (CPA) | 0.0059 | 0.0191 | 0.0279 |
Echinococcus granulosus | lamin | 0.0056 | 0.0175 | 0.0175 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0093 | 0.0419 | 0.0269 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Loa Loa (eye worm) | fibroinase | 0.0059 | 0.0191 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0282 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.0549 | 0.3471 | 0.4847 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0834 | 0.5382 | 1 |
Schistosoma mansoni | malate dehydrogenase | 0.0256 | 0.1507 | 0.28 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0059 | 0.0191 | 0.0191 |
Schistosoma mansoni | intermediate filament proteins | 0.0056 | 0.0175 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0447 | 0.0572 |
Chlamydia trachomatis | malate dehydrogenase | 0.0263 | 0.1555 | 1 |
Toxoplasma gondii | malate dehydrogenase MDH | 0.0549 | 0.3471 | 1 |
Plasmodium falciparum | malate dehydrogenase | 0.0549 | 0.3471 | 1 |
Schistosoma mansoni | malate dehydrogenase | 0.0263 | 0.1555 | 0.2889 |
Schistosoma mansoni | hypothetical protein | 0.0502 | 0.3154 | 0.586 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0061 | 0.0026 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0592 | 0.3759 | 0.5254 |
Trypanosoma brucei | malate dehydrogenase-related | 0.0237 | 0.138 | 0.2564 |
Loa Loa (eye worm) | matrixin family protein | 0.1094 | 0.7116 | 1 |
Leishmania major | cathepsin L-like protease | 0.0059 | 0.0191 | 0.0279 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0834 | 0.5382 | 0.5382 |
Brugia malayi | Cathepsin L-like precursor | 0.0039 | 0.0061 | 0.0086 |
Trypanosoma cruzi | mitochondrial malate dehydrogenase, putative | 0.0256 | 0.1507 | 0.28 |
Schistosoma mansoni | carbonic anhydrase | 0.0452 | 0.2821 | 0.5242 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0834 | 0.5382 | 0.7549 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0156 | 0.0841 | 0.1562 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0256 | 0.081 |
Mycobacterium ulcerans | malate dehydrogenase | 0.0263 | 0.1555 | 0.5307 |
Leishmania major | cathepsin L-like protease | 0.0156 | 0.0841 | 0.1496 |
Leishmania major | cathepsin L-like protease | 0.0059 | 0.0191 | 0.0279 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0056 | 0.0175 | 0.0187 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0059 | 0.0191 | 0.0551 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.0191 | 0.0269 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0097 | 0.0447 | 0.1287 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0452 | 0.2821 | 0.3929 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0452 | 0.2821 | 0.5242 |
Echinococcus multilocularis | L lactate dehydrogenase | 0.0312 | 0.1888 | 0.1888 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0256 | 0.081 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0549 | 0.3471 | 0.3471 |
Echinococcus granulosus | L lactate dehydrogenase B chain | 0.0549 | 0.3471 | 0.3471 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0834 | 0.5382 | 0.7563 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Leishmania major | carbonic anhydrase-like protein | 0.0834 | 0.5382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0447 | 0.0572 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Brugia malayi | lactate dehydrogenase. | 0.0549 | 0.3471 | 0.4878 |
Echinococcus multilocularis | cysteine protease | 0.0059 | 0.0191 | 0.0191 |
Onchocerca volvulus | Matrilysin homolog | 0.0354 | 0.2164 | 0.3196 |
Plasmodium falciparum | carbonic anhydrase | 0.0452 | 0.2821 | 0.8129 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0059 | 0.0191 | 0.0355 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0097 | 0.0447 | 0.0758 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Leishmania major | malate dehydrogenase | 0.0256 | 0.1507 | 0.2744 |
Trypanosoma brucei | cytosolic malate dehydrogenase | 0.0263 | 0.1555 | 0.2889 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0256 | 0.081 |
Brugia malayi | Matrixin family protein | 0.0354 | 0.2164 | 0.3042 |
Echinococcus granulosus | intermediate filament protein | 0.0056 | 0.0175 | 0.0175 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0097 | 0.0447 | 0.1534 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.0042 | 0.0059 |
Mycobacterium ulcerans | hydrolase | 0.0431 | 0.268 | 1 |
Onchocerca volvulus | 0.0059 | 0.0191 | 0.0198 | |
Onchocerca volvulus | 0.0059 | 0.0191 | 0.0198 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0059 | 0.0191 | 0.0355 |
Echinococcus multilocularis | lamin dm0 | 0.0056 | 0.0175 | 0.0175 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0059 | 0.0191 | 0.0551 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0431 | 0.268 | 0.3767 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 0.2164 | 0.3 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0447 | 0.0572 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0452 | 0.2821 | 0.3965 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0452 | 0.2821 | 0.5242 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0175 | 0.0187 |
Trypanosoma cruzi | malate dehydrogenase, putative | 0.0237 | 0.138 | 0.2564 |
Leishmania major | cathepsin L-like protease | 0.0059 | 0.0191 | 0.0279 |
Toxoplasma gondii | cathepsin CPL | 0.0059 | 0.0191 | 0.0435 |
Loa Loa (eye worm) | ctsf protein | 0.0059 | 0.0191 | 0.0211 |
Mycobacterium ulcerans | hypothetical protein | 0.0097 | 0.0447 | 0.0685 |
Loa Loa (eye worm) | matrixin family protein | 0.0785 | 0.5048 | 0.7076 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0282 | 0.034 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0037 | 0.0045 | 0.0045 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0452 | 0.2821 | 0.3965 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 0.2164 | 0.3 |
Plasmodium falciparum | thioredoxin reductase | 0.0037 | 0.0042 | 0.0121 |
Brugia malayi | intermediate filament protein | 0.0056 | 0.0175 | 0.0246 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0834 | 0.5382 | 0.7563 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Leishmania major | malate dehydrogenase, putative | 0.0549 | 0.3471 | 0.6421 |
Giardia lamblia | Malate dehydrogenase | 0.0263 | 0.1555 | 0.5 |
Onchocerca volvulus | 0.0059 | 0.0191 | 0.0198 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0156 | 0.0841 | 0.1562 |
Echinococcus granulosus | carbonic anhydrase | 0.0452 | 0.2821 | 0.2821 |
Brugia malayi | Probable malate dehydrogenase, mitochondrial precursor | 0.0256 | 0.1507 | 0.2118 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0097 | 0.0447 | 0.0388 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0834 | 0.5382 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0059 | 0.0191 | 0.0198 |
Onchocerca volvulus | 0.0056 | 0.0175 | 0.0173 | |
Loa Loa (eye worm) | malate dehydrogenase | 0.0263 | 0.1555 | 0.2139 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0191 | 0.0211 |
Schistosoma mansoni | malate dehydrogenase | 0.0549 | 0.3471 | 0.6449 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.0185 | 0.1035 | 0.1923 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0452 | 0.2821 | 0.5242 |
Plasmodium vivax | vivapain-2 | 0.0059 | 0.0191 | 0.0551 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0452 | 0.2821 | 0.3965 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0097 | 0.0447 | 0.0388 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0059 | 0.0191 | 0.0191 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0097 | 0.0447 | 0.0685 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0834 | 0.5382 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0097 | 0.0447 | 0.0628 |
Onchocerca volvulus | 0.0059 | 0.0191 | 0.0198 | |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0834 | 0.5382 | 1 |
Plasmodium falciparum | lactate dehydrogenase, putative | 0.0237 | 0.138 | 0.3976 |
Brugia malayi | Malate dehydrogenase, cytoplasmic | 0.0263 | 0.1555 | 0.2185 |
Brugia malayi | cathepsin L-like precursor | 0.0039 | 0.0061 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0168 | 0.0178 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0141 | 0.0743 | 0.4778 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0097 | 0.0447 | 0.1287 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0059 | 0.0191 | 0.0211 |
Echinococcus multilocularis | cysteine protease | 0.0059 | 0.0191 | 0.0191 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Plasmodium vivax | lactate dehydrogenase | 0.0549 | 0.3471 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0084 | 0.0356 | 0.1191 |
Trypanosoma cruzi | glycosomal malate dehydrogenase, putative | 0.0256 | 0.1507 | 0.28 |
Trypanosoma brucei | glycosomal malate dehydrogenase | 0.0256 | 0.1507 | 0.28 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0097 | 0.0447 | 0.0758 |
Onchocerca volvulus | Cathepsin L homolog | 0.0059 | 0.0191 | 0.0198 |
Echinococcus granulosus | carbonic anhydrase II | 0.0834 | 0.5382 | 0.5382 |
Toxoplasma gondii | lactate dehydrogenase LDH1 | 0.0549 | 0.3471 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0452 | 0.2821 | 0.3965 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0452 | 0.2821 | 0.5242 |
Brugia malayi | Matrixin family protein | 0.0354 | 0.2164 | 0.3042 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0059 | 0.0191 | 0.0191 |
Leishmania major | cytosolic malate dehydrogenase | 0.0263 | 0.1555 | 0.2833 |
Echinococcus granulosus | cathepsin l1 | 0.0059 | 0.0191 | 0.0191 |
Onchocerca volvulus | 0.0059 | 0.0191 | 0.0198 | |
Trypanosoma brucei | mitochondrial malate dehydrogenase | 0.0256 | 0.1507 | 0.28 |
Echinococcus multilocularis | musashi | 0.0056 | 0.0175 | 0.0175 |
Echinococcus multilocularis | malate dehydrogenase | 0.0256 | 0.1507 | 0.1507 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0097 | 0.0447 | 0.0758 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0549 | 0.3471 | 0.3471 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.0061 | 0.0391 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Onchocerca volvulus | 0.0059 | 0.0191 | 0.0198 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Loa Loa (eye worm) | intermediate filament protein | 0.0056 | 0.0175 | 0.0187 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Loa Loa (eye worm) | hypothetical protein | 0.0452 | 0.2821 | 0.3929 |
Entamoeba histolytica | malate dehydrogenase, putative | 0.0549 | 0.3471 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0059 | 0.0191 | 0.0551 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0097 | 0.0447 | 0.1534 |
Echinococcus multilocularis | carbonic anhydrase | 0.0452 | 0.2821 | 0.2821 |
Echinococcus granulosus | lactate dehydrogenase a | 0.0549 | 0.3471 | 0.3471 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0282 | 0.034 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0263 | 0.1555 | 1 |
Trypanosoma cruzi | cytosolic malate dehydrogenase, putative | 0.0263 | 0.1555 | 0.2889 |
Brugia malayi | Matrixin family protein | 0.0354 | 0.2164 | 0.3042 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0069 | 0.0256 | 0.081 |
Loa Loa (eye worm) | hypothetical protein | 0.0452 | 0.2821 | 0.3929 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Schistosoma mansoni | malate dehydrogenase | 0.0263 | 0.1555 | 0.2889 |
Onchocerca volvulus | 0.0502 | 0.3154 | 0.4699 | |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 0.268 | 0.373 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0093 | 0.0419 | 0.1428 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0592 | 0.3759 | 0.6985 |
Leishmania major | mitochondrial malate dehydrogenase | 0.0256 | 0.1507 | 0.2744 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0061 | 0.0026 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0549 | 0.3471 | 0.3471 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0073 | 0.0282 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0452 | 0.2821 | 0.3929 |
Onchocerca volvulus | 0.0354 | 0.2164 | 0.3196 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0059 | 0.0191 | 0.0211 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.1524 | 1 | 1 |
Echinococcus granulosus | L lactate dehydrogenase | 0.0312 | 0.1888 | 0.1888 |
Brugia malayi | Matrixin family protein | 0.0354 | 0.2164 | 0.3042 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0059 | 0.0191 | 0.0191 |
Brugia malayi | Matrixin family protein | 0.1094 | 0.7116 | 1 |
Onchocerca volvulus | 0.0056 | 0.0175 | 0.0173 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0059 | 0.0191 | 0.0355 |
Onchocerca volvulus | 0.0097 | 0.0447 | 0.0586 | |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0097 | 0.0447 | 0.0685 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Trypanosoma cruzi | glycosomal malate dehydrogenase, putative | 0.0256 | 0.1507 | 0.28 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0156 | 0.0841 | 0.1562 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0108 | 0.0519 | 0.0964 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0156 | 0.0841 | 0.1562 |
Entamoeba histolytica | cysteine protease, putative | 0.0059 | 0.0191 | 0.0551 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0059 | 0.0191 | 0.123 |
Brugia malayi | Cathepsin L-like precursor | 0.0059 | 0.0191 | 0.0269 |
Leishmania major | malate dehydrogenase, putative | 0.0237 | 0.138 | 0.2506 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.