Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | neural Wiskott Aldrich syndrome protein | 0.018 | 0.0751 | 0.0822 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0184 | 0.0768 | 0.084 |
Brugia malayi | Protein kinase domain | 0.0184 | 0.0768 | 0.0768 |
Echinococcus multilocularis | plexin a4 | 0.0067 | 0.0206 | 0.0225 |
Schistosoma mansoni | tyrosine kinase | 0.0183 | 0.0764 | 0.9188 |
Trichomonas vaginalis | STE family protein kinase | 0.0184 | 0.0768 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 4 | 0.1934 | 0.9137 | 1 |
Schistosoma mansoni | protein kinase | 0.0184 | 0.0768 | 0.9234 |
Echinococcus multilocularis | geminin | 0.0197 | 0.0831 | 0.091 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0184 | 0.0768 | 0.084 |
Trichomonas vaginalis | STE family protein kinase | 0.0184 | 0.0768 | 1 |
Loa Loa (eye worm) | STE/STE20/PAKB protein kinase | 0.2115 | 1 | 1 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.018 | 0.0751 | 0.0822 |
Echinococcus granulosus | geminin | 0.0197 | 0.0831 | 0.091 |
Echinococcus granulosus | neural Wiskott Aldrich syndrome protein | 0.018 | 0.0751 | 0.0822 |
Giardia lamblia | Kinase, STE STE20 | 0.0184 | 0.0768 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 4 | 0.1934 | 0.9137 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.0831 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0184 | 0.0768 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0184 | 0.0768 | 0.084 |
Entamoeba histolytica | protein kinase, putative | 0.0184 | 0.0768 | 1 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.0751 | 0.903 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0157 | 0.0157 |
Brugia malayi | WH1 domain containing protein | 0.018 | 0.0751 | 0.0751 |
Brugia malayi | P21-Rho-binding domain containing protein | 0.018 | 0.0751 | 0.0751 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.0751 | 0.903 |
Echinococcus multilocularis | p21 activated protein kinase 1 Dpak1 | 0.0184 | 0.0768 | 0.084 |
Schistosoma mansoni | plexin | 0.0056 | 0.0157 | 0.1883 |
Entamoeba histolytica | protein kinase, putative | 0.0184 | 0.0768 | 1 |
Brugia malayi | Plexin repeat family protein | 0.0056 | 0.0157 | 0.0157 |
Echinococcus granulosus | PAK box P21 Rho binding | 0.018 | 0.0751 | 0.0822 |
Schistosoma mansoni | wiskott-aldrich syndrome protein | 0.018 | 0.0751 | 0.903 |
Entamoeba histolytica | p21-activated kinase | 0.0184 | 0.0768 | 1 |
Schistosoma mansoni | protein kinase | 0.0184 | 0.0768 | 0.9234 |
Echinococcus granulosus | 3'partial|serine:threonine protein kinase PAK 2 | 0.018 | 0.0751 | 0.0822 |
Echinococcus granulosus | p21 activated protein kinase 1 Dpak1 | 0.0184 | 0.0768 | 0.084 |
Echinococcus granulosus | plexin a4 | 0.0067 | 0.0206 | 0.0225 |
Trichomonas vaginalis | STE family protein kinase | 0.0184 | 0.0768 | 1 |
Brugia malayi | plexin A | 0.0067 | 0.0206 | 0.0206 |
Trichomonas vaginalis | STE family protein kinase | 0.0184 | 0.0768 | 1 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.0184 | 0.0768 | 0.084 |
Entamoeba histolytica | protein kinase, putative | 0.0184 | 0.0768 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0183 | 0.0764 | 0.9188 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0184 | 0.0768 | 0.084 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | P21-Rho-binding domain-containing protein | 0.018 | 0.0751 | 0.0751 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.0751 | 0.903 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.0751 | 0.0751 |
Entamoeba histolytica | protein kinase, putative | 0.0184 | 0.0768 | 1 |
Onchocerca volvulus | 0.0056 | 0.0157 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.0831 | 1 |
Schistosoma mansoni | protein kinase | 0.018 | 0.0751 | 0.903 |
Brugia malayi | P21-Rho-binding domain containing protein | 0.018 | 0.0751 | 0.0751 |
Loa Loa (eye worm) | plexin A | 0.0067 | 0.0206 | 0.0206 |
Schistosoma mansoni | plexin | 0.0033 | 0.0044 | 0.0531 |
Schistosoma mansoni | protein kinase | 0.0184 | 0.0768 | 0.9234 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0044 | 0.0531 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.