Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.192 | 1 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.192 | 1 | 1 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.192 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.192 | 1 | 1 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.1096 | 0.5261 | 0.4742 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.1096 | 0.5261 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1096 | 0.5261 | 0.4742 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.1096 | 0.5261 | 0.4742 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.192 | 1 | 0.5 |
Entamoeba histolytica | trans-2,3-enoyl-CoA reductase, putative | 0.1096 | 0.5261 | 0.4742 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.192 | 1 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0833 | 0.375 | 0.7128 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.1096 | 0.5261 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.192 | 1 | 0.5 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0833 | 0.375 | 0.7128 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0353 | 0.0986 | 0.5 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.192 | 1 | 1 |
Onchocerca volvulus | 0.1096 | 0.5261 | 1 | |
Plasmodium falciparum | polyprenol reductase, putative | 0.1096 | 0.5261 | 0.5 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.1096 | 0.5261 | 0.4742 |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.1096 | 0.5261 | 1 |
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.1096 | 0.5261 | 0.5 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.1096 | 0.5261 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0833 | 0.375 | 0.7128 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.192 | 1 | 1 |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.1096 | 0.5261 | 1 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.1096 | 0.5261 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1096 | 0.5261 | 0.5261 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.192 | 1 | 1 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.1096 | 0.5261 | 1 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.1096 | 0.5261 | 0.4742 |
Plasmodium vivax | polyprenol reductase, putative | 0.1096 | 0.5261 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1096 | 0.5261 | 0.5261 |
Entamoeba histolytica | 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein | 0.1096 | 0.5261 | 0.4742 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.1096 | 0.5261 | 0.5261 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.192 | 1 | 1 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.1096 | 0.5261 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.1096 | 0.5261 | 0.4742 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1096 | 0.5261 | 0.4742 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.