Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0211 | 0.5639 | 0.5 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0211 | 0.5639 | 1 |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.0211 | 0.5639 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0338 | 1 | 1 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.0211 | 0.5639 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0338 | 1 | 1 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.0211 | 0.5639 | 0.5639 |
Onchocerca volvulus | 0.0211 | 0.5639 | 1 | |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.0338 | 1 | 1 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0211 | 0.5639 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0211 | 0.5639 | 0.5639 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0338 | 1 | 1 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.0211 | 0.5639 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 1 | 1 |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.0211 | 0.5639 | 0.5 |
Plasmodium falciparum | polyprenol reductase, putative | 0.0211 | 0.5639 | 0.5 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0211 | 0.5639 | 0.5 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.0211 | 0.5639 | 1 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0211 | 0.5639 | 0.5639 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.0338 | 1 | 0.5 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0338 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0338 | 1 | 0.5 |
Plasmodium vivax | polyprenol reductase, putative | 0.0211 | 0.5639 | 0.5 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.0338 | 1 | 1 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0338 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.