Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | acyl-CoA desaturase | 0.3589 | 0.8956 | 1 |
Leishmania major | fatty-acid desaturase, putative | 0.3976 | 1 | 1 |
Plasmodium vivax | stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative | 0.3589 | 0.8956 | 0.5 |
Onchocerca volvulus | 0.3976 | 1 | 1 | |
Mycobacterium ulcerans | hypothetical protein | 0.0387 | 0.0334 | 1 |
Mycobacterium ulcerans | linoleoyl-CoA desaturase, DesA3_2 | 0.0387 | 0.0334 | 1 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.3589 | 0.8956 | 0.892 |
Echinococcus multilocularis | Fatty acid desaturase, type 1 | 0.0387 | 0.0334 | 0.5 |
Brugia malayi | acyl-CoA desaturase | 0.3589 | 0.8956 | 1 |
Echinococcus multilocularis | Peptidase M, neutral zinc metallopeptidases, zinc binding site | 0.0387 | 0.0334 | 0.5 |
Mycobacterium tuberculosis | Class a beta-lactamase BlaC | 0.0304 | 0.0109 | 0.3267 |
Toxoplasma gondii | sphingolipid delta 4 desaturase/c-4 hydroxylase protein des2 family protein | 0.0387 | 0.0334 | 0.5 |
Mycobacterium tuberculosis | Probable conserved membrane protein | 0.0387 | 0.0334 | 1 |
Echinococcus granulosus | Sphingolipid delta4 desaturase DES1 | 0.0387 | 0.0334 | 0.5 |
Plasmodium falciparum | stearoyl-CoA desaturase | 0.3589 | 0.8956 | 0.5 |
Mycobacterium tuberculosis | Possible electron transfer protein FdxB | 0.0387 | 0.0334 | 1 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.3976 | 1 | 1 |
Mycobacterium tuberculosis | Probable transmembrane alkane 1-monooxygenase AlkB (alkane 1-hydroxylase) (lauric acid omega-hydroxylase) (omega-hydroxylase) (f | 0.0387 | 0.0334 | 1 |
Mycobacterium ulcerans | transmembrane alkane 1-monooxygenase AlkB | 0.0387 | 0.0334 | 1 |
Echinococcus multilocularis | Peptidase M, neutral zinc metallopeptidases, zinc binding site | 0.0387 | 0.0334 | 0.5 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.3589 | 0.8956 | 0.892 |
Echinococcus granulosus | Fatty acid desaturase type 1 | 0.0387 | 0.0334 | 0.5 |
Mycobacterium ulcerans | linoleoyl-CoA desaturase, DesA3 | 0.0387 | 0.0334 | 1 |
Onchocerca volvulus | 0.3976 | 1 | 1 | |
Schistosoma mansoni | fatty acid desaturase | 0.0387 | 0.0334 | 0.5 |
Mycobacterium ulcerans | electron transfer protein FdxB | 0.0387 | 0.0334 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0387 | 0.0334 | 1 |
Trypanosoma brucei | fatty acid desaturase, putative | 0.3976 | 1 | 1 |
Mycobacterium ulcerans | linoleoyl-CoA desaturase, DesA3 | 0.0387 | 0.0334 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Activity at GST-tagged IAR3 of Arabidopsis thaliana assessed as ABA release per mg of protein after 7 hrs by HPLC | ChEMBL. | 21310619 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.