Detailed information for compound 1507644

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 203.197 | Formula: C10H9N3O2
  • H donors: 1 H acceptors: 3 LogP: 1.28 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1cnon1)Nc1ccc(cc1)C
  • InChi: 1S/C10H9N3O2/c1-7-2-4-8(5-3-7)12-10(14)9-6-11-15-13-9/h2-6H,1H3,(H,12,14)
  • InChiKey: KGQFDVBLSTWCRJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.004 0.311 0.311
Echinococcus granulosus nephrin 0.0031 0.0863 0.0863
Schistosoma mansoni hypothetical protein 0.0031 0.0863 0.1012
Schistosoma mansoni neuroglian 0.004 0.311 0.3646
Brugia malayi Immunoglobulin I-set domain containing protein 0.0053 0.6283 1
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.004 0.311 0.495
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0031 0.0863 0.0863
Echinococcus multilocularis roundabout 2 0.004 0.311 0.311
Loa Loa (eye worm) projectin 0.0031 0.0863 0.1374
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.1639 0.2608
Loa Loa (eye worm) hypothetical protein 0.0031 0.0863 0.1374
Loa Loa (eye worm) hypothetical protein 0.0031 0.0863 0.1374
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0037 0.2246 0.2246
Schistosoma mansoni hemicentin 0.0031 0.0863 0.1012
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.004 0.311 0.3646
Echinococcus granulosus roundabout 2 0.004 0.311 0.311
Loa Loa (eye worm) hypothetical protein 0.0053 0.6283 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.311 0.4145
Loa Loa (eye worm) hypothetical protein 0.004 0.311 0.495
Echinococcus granulosus titin 0.0031 0.0863 0.0863
Echinococcus multilocularis neuroglian 0.0034 0.1471 0.1471
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.311 0.4145
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0031 0.0863 0.1374
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0034 0.1639 0.1639
Loa Loa (eye worm) CAMK protein kinase 0.0031 0.0863 0.1374
Echinococcus granulosus twitchin 0.0034 0.1471 0.1471
Schistosoma mansoni nephrin 0.004 0.311 0.3646
Loa Loa (eye worm) hypothetical protein 0.0043 0.3717 0.5917
Schistosoma mansoni myosin-binding protein-related 0.0031 0.0863 0.1012
Echinococcus granulosus titin 0.0031 0.0863 0.0863
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.311 0.4145
Schistosoma mansoni ephrin receptor 0.0033 0.124 0.1453
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0044 0.4094 0.6516
Echinococcus granulosus neuroglian 0.004 0.311 0.311
Onchocerca volvulus 0.0031 0.0863 0.5
Onchocerca volvulus 0.0031 0.0863 0.5
Echinococcus granulosus contactin 0.004 0.311 0.311
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0863 0.1012
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0863 0.1374
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.004 0.311 0.311
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.004 0.311 0.311
Brugia malayi hypothetical protein 0.0053 0.6283 1
Echinococcus granulosus neuroglian 0.0034 0.1471 0.1471
Brugia malayi Fibronectin type III domain containing protein 0.0053 0.6283 1
Schistosoma mansoni nephrin 0.0059 0.7754 0.9091
Echinococcus multilocularis contactin neuroglian septate junction protein 0.004 0.311 0.311
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0863 0.1374
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0033 0.124 0.124
Loa Loa (eye worm) hypothetical protein 0.0053 0.6283 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.2246 0.3575
Schistosoma mansoni cell adhesion molecule 0.0062 0.8529 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0863 0.1374
Echinococcus multilocularis titin 0.0031 0.0863 0.0863
Brugia malayi Immunoglobulin I-set domain containing protein 0.0044 0.4094 0.5961
Schistosoma mansoni cell adhesion molecule 0.004 0.311 0.3646
Onchocerca volvulus 0.0031 0.0863 0.5
Loa Loa (eye worm) hypothetical protein 0.0043 0.3717 0.5917
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.004 0.311 0.311
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.1639 0.1431
Schistosoma mansoni cell adhesion molecule 0.0031 0.0863 0.1012
Loa Loa (eye worm) hypothetical protein 0.0053 0.6283 1
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0034 0.1639 0.1639
Echinococcus multilocularis neuroglian 0.004 0.311 0.311
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0033 0.124 0.124
Schistosoma mansoni cell adhesion molecule 0.0031 0.0863 0.1012
Schistosoma mansoni cell adhesion molecule 0.004 0.311 0.3646
Echinococcus granulosus roundabout 2 0.004 0.311 0.311
Schistosoma mansoni titin 0.0031 0.0863 0.1012
Schistosoma mansoni titin 0.0031 0.0863 0.1012
Echinococcus multilocularis transfer RNA-Phe 0.0031 0.0863 0.0863
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.004 0.311 0.495
Echinococcus multilocularis roundabout 2 0.004 0.311 0.311

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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