Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.0751 | 0.0751 |
Trichomonas vaginalis | STE family protein kinase | 0.0184 | 0.0768 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 4 | 0.1934 | 0.9137 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0184 | 0.0768 | 0.084 |
Schistosoma mansoni | protein kinase | 0.0184 | 0.0768 | 0.9234 |
Entamoeba histolytica | protein kinase, putative | 0.0184 | 0.0768 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 4 | 0.1934 | 0.9137 | 1 |
Echinococcus multilocularis | plexin a4 | 0.0067 | 0.0206 | 0.0225 |
Trichomonas vaginalis | STE family protein kinase | 0.0184 | 0.0768 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0183 | 0.0764 | 0.9188 |
Echinococcus multilocularis | p21 activated protein kinase 1 Dpak1 | 0.0184 | 0.0768 | 0.084 |
Echinococcus multilocularis | neural Wiskott Aldrich syndrome protein | 0.018 | 0.0751 | 0.0822 |
Brugia malayi | Protein kinase domain | 0.0184 | 0.0768 | 0.0768 |
Brugia malayi | P21-Rho-binding domain containing protein | 0.018 | 0.0751 | 0.0751 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.0184 | 0.0768 | 0.084 |
Brugia malayi | P21-Rho-binding domain containing protein | 0.018 | 0.0751 | 0.0751 |
Schistosoma mansoni | protein kinase | 0.018 | 0.0751 | 0.903 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.0751 | 0.903 |
Entamoeba histolytica | p21-activated kinase | 0.0184 | 0.0768 | 1 |
Brugia malayi | Plexin repeat family protein | 0.0056 | 0.0157 | 0.0157 |
Trichomonas vaginalis | STE family protein kinase | 0.0184 | 0.0768 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0184 | 0.0768 | 0.084 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.0831 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0184 | 0.0768 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.0831 | 1 |
Echinococcus granulosus | geminin | 0.0197 | 0.0831 | 0.091 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.0751 | 0.903 |
Entamoeba histolytica | protein kinase, putative | 0.0184 | 0.0768 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0184 | 0.0768 | 0.084 |
Loa Loa (eye worm) | plexin A | 0.0067 | 0.0206 | 0.0206 |
Schistosoma mansoni | protein kinase | 0.0184 | 0.0768 | 0.9234 |
Schistosoma mansoni | plexin | 0.0056 | 0.0157 | 0.1883 |
Echinococcus granulosus | p21 activated protein kinase 1 Dpak1 | 0.0184 | 0.0768 | 0.084 |
Entamoeba histolytica | protein kinase, putative | 0.0184 | 0.0768 | 1 |
Brugia malayi | plexin A | 0.0067 | 0.0206 | 0.0206 |
Echinococcus granulosus | PAK box P21 Rho binding | 0.018 | 0.0751 | 0.0822 |
Trichomonas vaginalis | STE family protein kinase | 0.0184 | 0.0768 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0157 | 0.0157 |
Trichomonas vaginalis | STE family protein kinase | 0.0184 | 0.0768 | 1 |
Echinococcus granulosus | neural Wiskott Aldrich syndrome protein | 0.018 | 0.0751 | 0.0822 |
Onchocerca volvulus | 0.0056 | 0.0157 | 1 | |
Schistosoma mansoni | protein kinase | 0.0184 | 0.0768 | 0.9234 |
Schistosoma mansoni | plexin | 0.0033 | 0.0044 | 0.0531 |
Schistosoma mansoni | wiskott-aldrich syndrome protein | 0.018 | 0.0751 | 0.903 |
Echinococcus granulosus | plexin a4 | 0.0067 | 0.0206 | 0.0225 |
Echinococcus multilocularis | geminin | 0.0197 | 0.0831 | 0.091 |
Brugia malayi | WH1 domain containing protein | 0.018 | 0.0751 | 0.0751 |
Echinococcus granulosus | 3'partial|serine:threonine protein kinase PAK 2 | 0.018 | 0.0751 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0044 | 0.0044 |
Schistosoma mansoni | tyrosine kinase | 0.0183 | 0.0764 | 0.9188 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0184 | 0.0768 | 0.084 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0044 | 0.0531 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.0751 | 0.903 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.018 | 0.0751 | 0.0822 |
Giardia lamblia | Kinase, STE STE20 | 0.0184 | 0.0768 | 0.5 |
Loa Loa (eye worm) | P21-Rho-binding domain-containing protein | 0.018 | 0.0751 | 0.0751 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.