Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Candida albicans | beta-1,3-glucan synthase similar to S. cerevisiae GSC2 (YGR032W) and FKS1 (YLR342W) beta-1,3-glucan synthase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | protein kinase | 0.0376 | 0.1768 | 1 |
Brugia malayi | P21-Rho-binding domain containing protein | 0.022 | 0.0511 | 0.0511 |
Entamoeba histolytica | protein kinase, putative | 0.0224 | 0.0546 | 0.0277 |
Giardia lamblia | Kinase, STE STE20 | 0.0376 | 0.1768 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0372 | 0.1733 | 0.1733 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0376 | 0.1768 | 0.1628 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0376 | 0.1768 | 0.1628 |
Trichomonas vaginalis | STE family protein kinase | 0.0376 | 0.1768 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0376 | 0.1768 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0376 | 0.1768 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 4 | 0.1179 | 0.8232 | 1 |
Loa Loa (eye worm) | P21-Rho-binding domain-containing protein | 0.022 | 0.0511 | 0.0511 |
Echinococcus granulosus | serine:threonine protein kinase PAK 4 | 0.1179 | 0.8232 | 1 |
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.0256 | 0.0804 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0224 | 0.0546 | 0.0277 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0376 | 0.1768 | 0.1628 |
Brugia malayi | Protein kinase domain | 0.0376 | 0.1768 | 0.1768 |
Schistosoma mansoni | protein kinase | 0.022 | 0.0511 | 0.2889 |
Schistosoma mansoni | hypothetical protein | 0.022 | 0.0511 | 0.2889 |
Schistosoma mansoni | protein kinase | 0.0224 | 0.0546 | 0.3086 |
Trichomonas vaginalis | STE family protein kinase | 0.0224 | 0.0546 | 0.3086 |
Brugia malayi | P21-Rho-binding domain containing protein | 0.022 | 0.0511 | 0.0511 |
Echinococcus granulosus | p21 activated protein kinase 1 Dpak1 | 0.0376 | 0.1768 | 0.1628 |
Schistosoma mansoni | tyrosine kinase | 0.022 | 0.0511 | 0.2889 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0376 | 0.1768 | 0.1628 |
Schistosoma mansoni | wiskott-aldrich syndrome protein | 0.022 | 0.0511 | 0.2889 |
Schistosoma mansoni | serine/threonine protein kinase | 0.022 | 0.0511 | 0.2889 |
Schistosoma mansoni | hypothetical protein | 0.022 | 0.0511 | 0.2889 |
Brugia malayi | WH1 domain containing protein | 0.022 | 0.0511 | 0.0511 |
Entamoeba histolytica | p21-activated kinase | 0.0376 | 0.1768 | 1 |
Schistosoma mansoni | hypothetical protein | 0.022 | 0.0511 | 0.2889 |
Entamoeba histolytica | protein kinase, putative | 0.0376 | 0.1768 | 1 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.0224 | 0.0546 | 0.0045 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0372 | 0.1733 | 0.9803 |
Entamoeba histolytica | protein kinase, putative | 0.0224 | 0.0546 | 0.0277 |
Trichomonas vaginalis | STE family protein kinase | 0.0376 | 0.1768 | 1 |
Schistosoma mansoni | protein kinase | 0.0376 | 0.1768 | 1 |
Echinococcus multilocularis | p21 activated protein kinase 1 Dpak1 | 0.0376 | 0.1768 | 0.1628 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.