Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | plexin a4 | 0.018 | 0.0685 | 0.0824 |
Echinococcus granulosus | Immunoglobulin | 0.0079 | 0.0065 | 0.0079 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0094 | 0.0157 | 0.0157 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0277 | 0.1274 | 0.1274 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0277 | 0.1274 | 0.5 |
Loa Loa (eye worm) | RGS-3 protein | 0.0277 | 0.1274 | 0.1274 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0277 | 0.1274 | 0.1274 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0079 | 0.0065 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0065 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1274 | 0.1274 |
Echinococcus multilocularis | plexin a4 | 0.018 | 0.0685 | 0.0824 |
Echinococcus multilocularis | Immunoglobulin | 0.0079 | 0.0065 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0065 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0065 | 0.0065 |
Brugia malayi | Plexin repeat family protein | 0.0151 | 0.0503 | 0.0503 |
Brugia malayi | PXA domain containing protein | 0.0277 | 0.1274 | 0.1274 |
Schistosoma mansoni | axis inhibition protein axin | 0.0277 | 0.1274 | 0.1274 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0089 | 0.0089 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.1274 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0503 | 0.0503 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0079 | 0.0065 | 0.0065 |
Echinococcus multilocularis | G protein coupled receptor kinase 1 | 0.1034 | 0.5881 | 0.7075 |
Echinococcus multilocularis | expressed protein | 0.0277 | 0.1274 | 0.1533 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0079 | 0.0065 | 0.0065 |
Brugia malayi | hypothetical protein | 0.0277 | 0.1274 | 0.1274 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1274 | 0.1274 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0277 | 0.1274 | 0.1533 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0277 | 0.1274 | 0.1274 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0277 | 0.1274 | 0.1533 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0065 | 0.0065 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0277 | 0.1274 | 0.1274 |
Schistosoma mansoni | regulator of G protein signaling | 0.0277 | 0.1274 | 0.1274 |
Brugia malayi | hypothetical protein | 0.0079 | 0.0065 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1274 | 0.1274 |
Schistosoma mansoni | regulator of G protein signaling | 0.0277 | 0.1274 | 0.1274 |
Echinococcus multilocularis | Immunoglobulin | 0.0079 | 0.0065 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0089 | 0.0089 |
Echinococcus granulosus | axis inhibition protein axin | 0.0277 | 0.1274 | 0.1533 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0277 | 0.1274 | 0.1533 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0277 | 0.1274 | 0.1533 |
Schistosoma mansoni | vesicular amine transporter | 0.0079 | 0.0065 | 0.0065 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.1311 | 0.7569 | 0.9106 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0277 | 0.1274 | 0.1533 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0277 | 0.1274 | 0.1533 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0065 | 0.0065 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0277 | 0.1274 | 0.5 |
Schistosoma mansoni | regulator of G protein signaling | 0.0277 | 0.1274 | 0.1274 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0277 | 0.1274 | 0.1533 |
Echinococcus granulosus | roundabout 2 | 0.0079 | 0.0065 | 0.0079 |
Schistosoma mansoni | axis inhibition protein axin | 0.0277 | 0.1274 | 0.1274 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0277 | 0.1274 | 0.1533 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0277 | 0.1274 | 0.5 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0277 | 0.1274 | 0.1274 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0277 | 0.1274 | 0.5 |
Brugia malayi | PXA domain containing protein | 0.0277 | 0.1274 | 0.1274 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0277 | 0.1274 | 0.1274 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0277 | 0.1274 | 0.1533 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0079 | 0.0065 | 0.0079 |
Echinococcus granulosus | G protein coupled receptor kinase 1 | 0.1034 | 0.5881 | 0.7075 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0079 | 0.0065 | 0.0065 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.1274 | 0.5 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.1311 | 0.7569 | 0.9106 |
Schistosoma mansoni | nephrin | 0.0079 | 0.0065 | 0.0065 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0277 | 0.1274 | 0.1274 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0277 | 0.1274 | 0.1533 |
Echinococcus multilocularis | roundabout 2 | 0.0079 | 0.0065 | 0.0079 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0277 | 0.1274 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1274 | 0.1274 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.1433 | 0.8312 | 0.8312 |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.1433 | 0.8312 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0065 | 0.0065 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1311 | 0.7569 | 0.7569 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.1433 | 0.8312 | 1 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1433 | 0.8312 | 0.8312 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0277 | 0.1274 | 0.1533 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1311 | 0.7569 | 0.7569 |
Schistosoma mansoni | plexin | 0.0151 | 0.0503 | 0.0503 |
Schistosoma mansoni | plexin | 0.0083 | 0.0089 | 0.0089 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.1433 | 0.8312 | 0.8312 |
Schistosoma mansoni | regulator of G protein signaling | 0.0277 | 0.1274 | 0.1274 |
Echinococcus granulosus | axis inhibition protein axin | 0.0277 | 0.1274 | 0.1533 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0277 | 0.1274 | 0.1533 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0277 | 0.1274 | 0.1274 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0277 | 0.1274 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0065 | 0.0065 |
Onchocerca volvulus | 0.0151 | 0.0503 | 1 | |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0277 | 0.1274 | 0.1533 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.1311 | 0.7569 | 0.7569 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0277 | 0.1274 | 0.1274 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1274 | 0.1274 |
Schistosoma mansoni | cell adhesion molecule | 0.0079 | 0.0065 | 0.0065 |
Echinococcus granulosus | defective proboscis extension response | 0.0079 | 0.0065 | 0.0079 |
Schistosoma mansoni | regulator of G protein signaling | 0.0277 | 0.1274 | 0.1274 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0065 | 0.0065 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0277 | 0.1274 | 0.1533 |
Echinococcus granulosus | twitchin | 0.0086 | 0.0109 | 0.0131 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0277 | 0.1274 | 0.1274 |
Entamoeba histolytica | hypothetical protein | 0.0277 | 0.1274 | 0.5 |
Loa Loa (eye worm) | plexin A | 0.018 | 0.0685 | 0.0685 |
Brugia malayi | hypothetical protein | 0.0277 | 0.1274 | 0.1274 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0079 | 0.0065 | 0.0079 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0094 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1274 | 0.1274 |
Echinococcus granulosus | expressed protein | 0.0277 | 0.1274 | 0.1533 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0277 | 0.1274 | 0.5 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0277 | 0.1274 | 0.1274 |
Echinococcus multilocularis | neuroglian | 0.0079 | 0.0065 | 0.0079 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0277 | 0.1274 | 0.1533 |
Echinococcus granulosus | neuroglian | 0.0079 | 0.0065 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0065 | 0.0065 |
Brugia malayi | plexin A | 0.018 | 0.0685 | 0.0685 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.