Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | titin | 0.017 | 0.0892 | 0.0892 |
Echinococcus multilocularis | transfer RNA-Phe | 0.017 | 0.0892 | 0.0892 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.0892 | 0.1419 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0219 | 0.3131 | 0.415 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.017 | 0.0892 | 0.1419 |
Brugia malayi | hypothetical protein | 0.0288 | 0.6288 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0219 | 0.3131 | 0.3131 |
Onchocerca volvulus | 0.017 | 0.0892 | 0.5 | |
Echinococcus granulosus | neuroglian | 0.0219 | 0.3131 | 0.3131 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0219 | 0.3131 | 0.498 |
Schistosoma mansoni | cell adhesion molecule | 0.0219 | 0.3131 | 0.3672 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.024 | 0.4088 | 0.5923 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.0892 | 0.1419 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0187 | 0.1658 | 0.2637 |
Loa Loa (eye worm) | hypothetical protein | 0.0219 | 0.3131 | 0.498 |
Echinococcus granulosus | twitchin | 0.0183 | 0.1473 | 0.1473 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0219 | 0.3131 | 0.3131 |
Schistosoma mansoni | neuroglian | 0.0219 | 0.3131 | 0.3672 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0288 | 0.6288 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0219 | 0.3131 | 0.415 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.017 | 0.0892 | 0.1419 |
Schistosoma mansoni | titin | 0.017 | 0.0892 | 0.1046 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.017 | 0.0892 | 0.0892 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.02 | 0.2239 | 0.2239 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.2239 | 0.3561 |
Loa Loa (eye worm) | hypothetical protein | 0.0288 | 0.6288 | 1 |
Schistosoma mansoni | ephrin receptor | 0.0178 | 0.1268 | 0.1487 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0219 | 0.3131 | 0.3672 |
Echinococcus granulosus | roundabout 2 | 0.0219 | 0.3131 | 0.3131 |
Echinococcus granulosus | roundabout 2 | 0.0219 | 0.3131 | 0.3131 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.024 | 0.4088 | 0.6502 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.017 | 0.0892 | 0.1419 |
Schistosoma mansoni | hemicentin | 0.017 | 0.0892 | 0.1046 |
Loa Loa (eye worm) | hypothetical protein | 0.0288 | 0.6288 | 1 |
Schistosoma mansoni | myosin-binding protein-related | 0.017 | 0.0892 | 0.1046 |
Schistosoma mansoni | nephrin | 0.0321 | 0.7761 | 0.9101 |
Onchocerca volvulus | 0.017 | 0.0892 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0288 | 0.6288 | 1 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.0892 | 0.1046 |
Schistosoma mansoni | nephrin | 0.0219 | 0.3131 | 0.3672 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.3712 | 0.5904 |
Echinococcus multilocularis | roundabout 2 | 0.0219 | 0.3131 | 0.3131 |
Echinococcus granulosus | contactin | 0.0219 | 0.3131 | 0.3131 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0219 | 0.3131 | 0.415 |
Loa Loa (eye worm) | projectin | 0.017 | 0.0892 | 0.1419 |
Loa Loa (eye worm) | CAMK protein kinase | 0.017 | 0.0892 | 0.1419 |
Echinococcus granulosus | neuroglian | 0.0183 | 0.1473 | 0.1473 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0219 | 0.3131 | 0.3131 |
Echinococcus multilocularis | neuroglian | 0.0219 | 0.3131 | 0.3131 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0219 | 0.3131 | 0.498 |
Schistosoma mansoni | cell adhesion molecule | 0.0219 | 0.3131 | 0.3672 |
Echinococcus multilocularis | neuroglian | 0.0183 | 0.1473 | 0.1473 |
Onchocerca volvulus | 0.017 | 0.0892 | 0.5 | |
Schistosoma mansoni | cell adhesion molecule | 0.017 | 0.0892 | 0.1046 |
Echinococcus multilocularis | Down syndrome cell adhesion molecule | 0.0187 | 0.1658 | 0.1658 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0187 | 0.1658 | 0.142 |
Schistosoma mansoni | cell adhesion molecule | 0.0338 | 0.8527 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.017 | 0.0892 | 0.1046 |
Echinococcus multilocularis | roundabout 2 | 0.0219 | 0.3131 | 0.3131 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0178 | 0.1268 | 0.1268 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0219 | 0.3131 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.3712 | 0.5904 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0178 | 0.1268 | 0.1268 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.017 | 0.0892 | 0.1419 |
Echinococcus granulosus | titin | 0.017 | 0.0892 | 0.0892 |
Echinococcus granulosus | Down syndrome cell adhesion molecule | 0.0187 | 0.1658 | 0.1658 |
Schistosoma mansoni | titin | 0.017 | 0.0892 | 0.1046 |
Schistosoma mansoni | cell adhesion molecule | 0.017 | 0.0892 | 0.1046 |
Echinococcus granulosus | titin | 0.017 | 0.0892 | 0.0892 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0219 | 0.3131 | 0.3131 |
Echinococcus granulosus | nephrin | 0.017 | 0.0892 | 0.0892 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0288 | 0.6288 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.