Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | protein tyrosine phosphatase n9 | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | carboxylesterase | 0.0139 | 0.1027 | 0.102 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | hypothetical protein | 0.0104 | 0.0693 | 0.0686 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0036 | 0.0036 | 0.0085 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0007 | 0.0018 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | protein-tyrosine phosphatase n9 | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0202 | 0.1635 | 0.5 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | glycogen phosphorylase | 0.0466 | 0.4189 | 0.4184 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0466 | 0.4189 | 0.4184 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Trypanosoma brucei | RNA helicase, putative | 0.0104 | 0.0693 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0139 | 0.1027 | 0.102 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | protein-tyrosine phosphatase Lar-like precursor, putative | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | rgs-gaip interacting protein gipc | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0202 | 0.1635 | 0.3904 |
Trichomonas vaginalis | pten, drome, putative | 0.0036 | 0.0036 | 0.0085 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0036 | 0.0036 | 0.0028 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0466 | 0.4189 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0466 | 0.4189 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | carboxylesterase 5A | 0.0139 | 0.1027 | 0.102 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0466 | 0.4189 | 0.4184 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0466 | 0.4189 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0139 | 0.1027 | 0.102 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0139 | 0.1027 | 0.102 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | pcd6 interacting protein-related | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0036 | 0.0036 | 1 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0202 | 0.1635 | 0.5 |
Loa Loa (eye worm) | protein-tyrosine phosphatase 1 | 0.0036 | 0.0036 | 0.0028 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0036 | 0.0036 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Entamoeba histolytica | Pten 3-phosphoinositide phosphatase, putative | 0.0036 | 0.0036 | 0.0085 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | dual specificity protein phosphatase CDC14B | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | receptor protein tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.1027 | 0.102 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.1027 | 0.102 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | acetylcholinesterase | 0.0139 | 0.1027 | 0.102 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | protein tyrosine phosphatase n9 | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | acetylcholinesterase | 0.0139 | 0.1027 | 0.102 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0466 | 0.4189 | 0.4184 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | 0.0036 | 0.0036 | 0.0028 | |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0036 | 0.0036 | 0.0028 |
Trypanosoma brucei | protein tyrosine phosphatase 1 | 0.0036 | 0.0036 | 0.0513 |
Schistosoma mansoni | glycogen phosphorylase | 0.0466 | 0.4189 | 0.4184 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0007 | 0.0018 |
Brugia malayi | Protein-tyrosine phosphatase 1 | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | glycogen phosphorylase | 0.0466 | 0.4189 | 0.4184 |
Brugia malayi | carbohydrate phosphorylase | 0.0466 | 0.4189 | 0.4184 |
Leishmania major | protein-tyrosine phosphatase 1-like protein | 0.0036 | 0.0036 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | Receptor type tyrosine protein phosphatase O | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0466 | 0.4189 | 0.4184 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0139 | 0.1027 | 0.102 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0202 | 0.1635 | 0.3904 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0036 | 0.0036 | 1 |
Echinococcus granulosus | Receptor type tyrosine protein phosphatase O | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | non-receptor protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0466 | 0.4189 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0139 | 0.1027 | 0.102 |
Echinococcus granulosus | acetylcholinesterase | 0.0139 | 0.1027 | 0.102 |
Brugia malayi | Dual specificity protein phosphatase CDC14B | 0.0036 | 0.0036 | 0.0028 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0466 | 0.4189 | 1 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase H | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine-phosphatase | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | receptor protein tyrosine phosphatase n (ia2) | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | glycogen phosphorylase | 0.0466 | 0.4189 | 0.4184 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Carboxylesterase family protein | 0.0139 | 0.1027 | 0.102 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0466 | 0.4189 | 0.4184 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | glycogen phosphorylase | 0.0202 | 0.1635 | 0.1629 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | protein-tyrosine phosphatase non-receptor type nt5 | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0036 | 0.0036 | 0.0028 |
Giardia lamblia | Glycogen phosphorylase | 0.0466 | 0.4189 | 1 |
Leishmania major | tyrosine specific protein phosphatase, putative | 0.0036 | 0.0036 | 1 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0036 | 0.0036 | 0.0028 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0036 | 0.0036 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | receptor protein tyrosine phosphatase n (ia2) | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0036 | 0.0036 | 0.0028 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0036 | 0.0036 | 0.0028 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0036 | 0.0036 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0036 | 0.0028 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0466 | 0.4189 | 0.5 |
Schistosoma mansoni | receptor protein tyrosine phosphatase r (pcptp1) | 0.0036 | 0.0036 | 0.0028 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.0202 | 0.1635 | 0.3904 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0036 | 0.0036 | 0.0028 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
permeability (ADMET) | = 0.8 10'-6 cm/s | Permeability across apical to basolateral side in human Caco2 cells | ChEMBL. | 21592789 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.