Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | phosphoglycerate kinase | 0.0099 | 0.0936 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0045 | 0.0334 | 0.0568 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0038 | 0.0038 |
Plasmodium vivax | phosphoglycerate kinase, putative | 0.0099 | 0.0936 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.0427 | 0.0725 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0025 | 0.0116 | 0.0116 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.1366 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Brugia malayi | G-protein coupled receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | neuropeptide receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Serotonin receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0025 | 0.0116 | 0.0116 |
Brugia malayi | sulfakinin receptor protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0025 | 0.0116 | 0.0116 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Schistosoma mansoni | opsin-like receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0088 | 0.0812 | 0.138 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0275 | 0.0468 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.1366 |
Echinococcus multilocularis | g protein coupled receptor | 0.0025 | 0.0116 | 0.0116 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0936 | 0.1592 |
Chlamydia trachomatis | phosphoglycerate kinase | 0.0099 | 0.0936 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0025 | 0.0116 | 0.0116 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0655 | 0.1113 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0099 | 0.0936 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Protein kinase domain containing protein | 0.0543 | 0.5881 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0025 | 0.0116 | 0.0116 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | neuropeptide F receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0045 | 0.0334 | 0.0334 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0088 | 0.0812 | 0.138 |
Brugia malayi | Serotonin receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0025 | 0.0116 | 0.0116 |
Echinococcus multilocularis | neuropeptide receptor | 0.0025 | 0.0116 | 0.0116 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0045 | 0.0334 | 0.0568 |
Schistosoma mansoni | amine GPCR | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Melatonin receptor type 1A | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | g protein coupled receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | serotonin receptor | 0.0025 | 0.0116 | 0.0116 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.2048 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0812 | 0.138 |
Echinococcus granulosus | dna polymerase kappa | 0.0045 | 0.0334 | 0.0568 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | g protein coupled receptor | 0.0025 | 0.0116 | 0.0116 |
Giardia lamblia | Phosphoglycerate kinase | 0.0099 | 0.0936 | 0.1086 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.0427 | 0.0725 |
Schistosoma mansoni | biogenic amine receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | TAR-binding protein | 0.0074 | 0.0655 | 0.1113 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0025 | 0.0116 | 0.0116 |
Echinococcus granulosus | somatostatin receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | neuropeptide F receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | larval opioid receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | geminin | 0.0197 | 0.2029 | 0.345 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0045 | 0.0334 | 0.0568 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.2029 | 0.345 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0075 | 0.0664 | 0.1129 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0655 | 0.1113 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.2048 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0038 | 0.0065 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0038 | 0.0065 |
Onchocerca volvulus | Dual specificity protein kinase TTK homolog | 0.0543 | 0.5881 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0275 | 0.0468 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0025 | 0.0116 | 0.0116 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0655 | 0.1113 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | serotonin transporter | 0.0088 | 0.0812 | 0.138 |
Brugia malayi | RE15519p | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | tar DNA binding protein | 0.0074 | 0.0655 | 0.1113 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Dopamine receptor protein 2 | 0.0025 | 0.0116 | 0.0197 |
Plasmodium falciparum | phosphoglycerate kinase | 0.0099 | 0.0936 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0018 | 0.0039 | 0.0066 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.2048 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0038 | 0.0065 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | TTK protein kinase | 0.0543 | 0.5881 | 1 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.2048 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0045 | 0.0334 | 0.2048 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0074 | 0.0655 | 0.1113 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.0275 | 0.0468 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0543 | 0.5881 | 1 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.0427 | 0.0725 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.2048 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0038 | 0.0065 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0025 | 0.0116 | 0.0116 |
Schistosoma mansoni | opsin-like receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | biogenic amine receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | tar DNA binding protein | 0.0074 | 0.0655 | 0.0655 |
Brugia malayi | Phosphoglycerate kinase | 0.0036 | 0.0239 | 0.0406 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0045 | 0.0334 | 0.2048 |
Echinococcus multilocularis | allatostatin A receptor | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | G protein-coupled receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | fmrfamide receptor | 0.0025 | 0.0116 | 0.0116 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Dopamine receptor protein 1 | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0038 | 0.0065 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0038 | 0.0038 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Echinococcus granulosus | allatostatin A receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0812 | 0.138 |
Echinococcus multilocularis | g protein coupled receptor | 0.0025 | 0.0116 | 0.0116 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0053 | 0.0427 | 0.0725 |
Wolbachia endosymbiont of Brugia malayi | phosphoglycerate kinase | 0.0099 | 0.0936 | 0.5 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Mycobacterium tuberculosis | Probable phosphoglycerate kinase Pgk | 0.0099 | 0.0936 | 1 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0099 | 0.0936 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.2048 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0045 | 0.0334 | 0.0568 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.0427 | 0.0427 |
Mycobacterium leprae | Probable phosphoglycerate kinase Pgk | 0.0099 | 0.0936 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Trichomonas vaginalis | phosphoglycerate kinase, putative | 0.0099 | 0.0936 | 0.1086 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0025 | 0.0116 | 0.0116 |
Giardia lamblia | Kinase, TTK | 0.0543 | 0.5881 | 1 |
Treponema pallidum | phosphoglycerate kinase | 0.0099 | 0.0936 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0038 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | amine GPCR | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | sex peptide receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0025 | 0.0116 | 0.0197 |
Toxoplasma gondii | phosphoglycerate kinase PGKI | 0.0099 | 0.0936 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0655 | 0.1113 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.0427 | 0.0427 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0053 | 0.0427 | 0.0725 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0025 | 0.0116 | 0.0116 |
Trypanosoma cruzi | phosphoglycerate kinase, putative | 0.0099 | 0.0936 | 1 |
Schistosoma mansoni | phosphoglycerate kinase | 0.0099 | 0.0936 | 0.1592 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0655 | 0.1113 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0045 | 0.0334 | 0.0568 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0812 | 0.138 |
Echinococcus multilocularis | neuropeptide receptor | 0.0025 | 0.0116 | 0.0116 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0025 | 0.0116 | 0.0197 |
Leishmania major | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.1366 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | geminin | 0.0197 | 0.2029 | 0.2029 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0075 | 0.0664 | 0.6096 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | dual specificity serine/threonine tyrosine kinase | 0.0543 | 0.5881 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | biogenic amine receptor | 0.0025 | 0.0116 | 0.0197 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.2048 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.0427 | 0.0725 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0044 | 0.0319 | 0.3409 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Leishmania major | phosphoglycerate kinase C, glycosomal | 0.0099 | 0.0936 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0664 | 0.1129 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0116 |
Echinococcus granulosus | neuropeptide s receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.2048 |
Echinococcus granulosus | fmrfamide receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.048 | 0.0816 |
Echinococcus granulosus | orexin receptor type 2 | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Echinococcus granulosus | g protein coupled receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | serotonin transporter | 0.0088 | 0.0812 | 0.0812 |
Echinococcus granulosus | phosphoglycerate kinase 1 | 0.0099 | 0.0936 | 0.1592 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0038 | 0.0065 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0025 | 0.0116 | 0.0116 |
Brugia malayi | RNA binding protein | 0.0074 | 0.0655 | 0.1113 |
Schistosoma mansoni | amine GPCR | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0116 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0045 | 0.0334 | 0.1366 |
Schistosoma mansoni | amine GPCR | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0025 | 0.0116 | 0.0197 |
Toxoplasma gondii | phosphoglycerate kinase PGKII | 0.0099 | 0.0936 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.048 | 0.0816 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0025 | 0.0116 | 0.0197 |
Trichomonas vaginalis | phosphoglycerate kinase, putative | 0.0099 | 0.0936 | 0.1086 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0074 | 0.0655 | 0.1113 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0038 | 0.0065 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.048 | 0.0816 |
Echinococcus multilocularis | sex peptide receptor | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.048 | 0.0816 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.1366 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | serotonin receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | phosphoglycerate kinase 1 | 0.0099 | 0.0936 | 0.0936 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Brugia malayi | follicle stimulating hormone receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Dopamine receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | dual specificity serine:threonine tyrosine | 0.0543 | 0.5881 | 0.5881 |
Brugia malayi | TAR-binding protein | 0.0074 | 0.0655 | 0.1113 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | RNA binding protein | 0.0074 | 0.0655 | 0.1113 |
Schistosoma mansoni | opsin-like receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | neuropeptide receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0038 | 0.0065 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | serotonin transporter b | 0.0088 | 0.0812 | 0.138 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0038 | 0.0038 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0116 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0025 | 0.0116 | 0.0116 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | neuropeptide receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | serotonin receptor | 0.0025 | 0.0116 | 0.0116 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0116 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0088 | 0.0812 | 0.138 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | fmrfamide receptor | 0.0025 | 0.0116 | 0.0116 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | phosphoglycerate kinase | 0.0099 | 0.0936 | 0.1592 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.2029 | 0.345 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Phosphoglycerate kinase | 0.0099 | 0.0936 | 0.1592 |
Echinococcus multilocularis | dna polymerase kappa | 0.0045 | 0.0334 | 0.0334 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0116 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | neuropeptide receptor | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Brugia malayi | G-protein coupled receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Mycobacterium ulcerans | phosphoglycerate kinase | 0.0099 | 0.0936 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0116 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | somatostatin receptor | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0038 | 0.0065 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0025 | 0.0116 | 0.0116 |
Brugia malayi | ORL1-like opioid receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | myosin xvIII | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0038 | 0.0065 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.2048 |
Schistosoma mansoni | adenoreceptor | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0025 | 0.0116 | 0.0197 |
Trypanosoma brucei | unspecified product | 0.0045 | 0.0334 | 0.2048 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0025 | 0.0116 | 0.0116 |
Onchocerca volvulus | 0.0088 | 0.0812 | 0.138 | |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0088 | 0.0812 | 0.138 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0543 | 0.5881 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.1366 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0025 | 0.0116 | 0.0116 |
Brugia malayi | AKH receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | dna polymerase eta | 0.0075 | 0.0664 | 0.1129 |
Echinococcus granulosus | dual specificity serine:threonine tyrosine | 0.0543 | 0.5881 | 1 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Echinococcus granulosus | g-protein coupled receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | putative neuropeptide receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0025 | 0.0116 | 0.0116 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0045 | 0.0334 | 0.2048 |
Leishmania major | phosphoglycerate kinase B, cytosolic | 0.0099 | 0.0936 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0025 | 0.0116 | 0.0197 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0044 | 0.0319 | 0.1154 |
Brugia malayi | GnHR receptor homolog | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | DNA polymerase eta | 0.0075 | 0.0664 | 0.1129 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Trypanosoma brucei | phosphoglycerate kinase | 0.0036 | 0.0239 | 0.079 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0025 | 0.0116 | 0.0197 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0025 | 0.0116 | 0.0197 |
Onchocerca volvulus | 0.0025 | 0.0116 | 0.0197 | |
Trypanosoma brucei | phosphoglycerate kinase, putative | 0.0036 | 0.0239 | 0.079 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Leishmania major | DNA polymerase eta, putative | 0.0075 | 0.0664 | 0.6096 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0334 | 0.2048 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0116 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0025 | 0.0116 | 0.0116 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0075 | 0.0664 | 0.6404 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.0427 | 0.0725 |
Schistosoma mansoni | amine GPCR | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0025 | 0.0116 | 0.0197 |
Leishmania major | DNA polymerase eta, putative | 0.0044 | 0.0319 | 0.1154 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0088 | 0.0812 | 0.138 |
Entamoeba histolytica | phosphoglycerate kinase, putative | 0.0099 | 0.0936 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | neuropeptide receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0025 | 0.0116 | 0.0116 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0025 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0025 | 0.0116 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0116 | 0.0197 |
Echinococcus multilocularis | dna polymerase eta | 0.0075 | 0.0664 | 0.0664 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 0.0032 M | In vitro antiviral activity against herpes simplex virus type 2 (HSV-2) in Vero cells. | ChEMBL. | 3950908 |
ED50 (functional) | > 0.005 M | In vitro antiviral activity against parainfluenza type 3 virus in Vero cells. | ChEMBL. | 3950908 |
ED50 (functional) | > 0.005 M | In vitro antiviral activity against measles virus in Vero cells | ChEMBL. | 3950908 |
ED50 (functional) | = 0.005 M | In vitro antiviral activity against vaccinia virus in Vero cells. | ChEMBL. | 3950908 |
ID50 (functional) | 0 M | In vitro inhibitory effect of the compound on growth of lewis lung carcinoma cells; ND is Not Determined | ChEMBL. | 3950908 |
ID50 (functional) | 0 M | In vitro inhibitory effect of the compound on growth of B16 melanoma cells; ND is Not Determined | ChEMBL. | 3950908 |
ID50 (functional) | > 0.0001 M | In vitro inhibitory effect of the compound on growth of L1210 leukemia cells | ChEMBL. | 3950908 |
ID50 (functional) | > 0.0001 M | In vitro inhibitory effect of the compound on growth of P388 leukemia cell | ChEMBL. | 3950908 |
MTC (functional) | = 0.005 M | Maximum tolerated concentration against Vero cells. | ChEMBL. | 3950908 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.