Detailed information for compound 1541109

Basic information

Technical information
  • TDR Targets ID: 1541109
  • Name: 2-[4-(furan-3-ylmethyl)-1-(3-methylbutyl)pipe razin-2-yl]ethanol
  • MW: 280.406 | Formula: C16H28N2O2
  • H donors: 1 H acceptors: 1 LogP: 2.06 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCC1CN(CCN1CCC(C)C)Cc1ccoc1
  • InChi: 1S/C16H28N2O2/c1-14(2)3-6-18-8-7-17(12-16(18)4-9-19)11-15-5-10-20-13-15/h5,10,13-14,16,19H,3-4,6-9,11-12H2,1-2H3
  • InChiKey: PCGQRNXUOBFPRV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[4-(3-furylmethyl)-1-isopentyl-piperazin-2-yl]ethanol
  • 2-[4-(3-furylmethyl)-1-isopentyl-2-piperazinyl]ethanol
  • 2-[4-(3-furylmethyl)-1-isoamyl-piperazin-2-yl]ethanol
  • SMR000318665
  • 2-[4-(3-furylmethyl)-1-(3-methylbutyl)piperazin-2-yl]ethanol
  • MLS000735378

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0028 0.4038
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.007 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.0145 0.8624 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0028 0.0424 0.0552
Schistosoma mansoni hypothetical protein 0.0165 1 1
Entamoeba histolytica hypothetical protein 0.0145 0.8624 1
Echinococcus granulosus carboxylesterase 5A 0.0132 0.7688 0.7688
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.007 0.007
Entamoeba histolytica hypothetical protein 0.0145 0.8624 1
Brugia malayi Steroid receptor seven-up type 2 0.0028 0.0424 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.007 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.007 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0424 0.0424
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0424 0.0424
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0424 0.0424
Entamoeba histolytica hypothetical protein 0.0145 0.8624 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0424 0.0552
Schistosoma mansoni jun-related protein 0.0066 0.3057 0.3057
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0424 0.0424
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0028 0.0424 0.0424
Schistosoma mansoni hypothetical protein 0.0066 0.3057 0.3057
Loa Loa (eye worm) hypothetical protein 0.0132 0.7688 1
Schistosoma mansoni hypothetical protein 0.0165 1 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0028 0.0424 0.0424
Brugia malayi bZIP transcription factor family protein 0.0081 0.4121 0.4779
Loa Loa (eye worm) hypothetical protein 0.0028 0.0424 0.0552
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0028 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.007 1
Loa Loa (eye worm) steroid hormone receptor 0.0028 0.0424 0.0552
Onchocerca volvulus Bile acid receptor homolog 0.0028 0.0424 0.1463
Loa Loa (eye worm) hypothetical protein 0.0132 0.7688 1
Echinococcus granulosus dna polymerase eta 0.0023 0.007 0.007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0424 0.0424
Schistosoma mansoni ap endonuclease 0.0023 0.0028 0.0028
Brugia malayi Carboxylesterase family protein 0.0132 0.7688 0.8915
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0145 0.8624 0.8624
Brugia malayi MH2 domain containing protein 0.0116 0.6584 0.7634
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0028 0.4038
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0424 0.0424
Echinococcus granulosus acetylcholinesterase 0.0132 0.7688 0.7688
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0028 0.5
Schistosoma mansoni ap endonuclease 0.0023 0.0028 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0028 0.0424 0.0552
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.007 1
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.007 1
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.007 1
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.007 1
Schistosoma mansoni transcription factor LCR-F1 0.0145 0.8624 0.8624
Leishmania major DNA polymerase kappa, putative 0.0023 0.007 1
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.007 1
Echinococcus granulosus ecdysone induced protein 78C 0.0028 0.0424 0.0424
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0028 0.0424 0.0552
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0028 0.0424 0.0552
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0028 0.0424 0.0424
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.007 1
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0028 0.4038
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0132 0.7688 0.7688
Schistosoma mansoni retinoic acid receptor RXR 0.0028 0.0424 0.0424
Echinococcus granulosus acetylcholinesterase 0.0132 0.7688 0.7688
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0028 0.0424 0.0424
Onchocerca volvulus Protein ultraspiracle homolog 0.0028 0.0424 0.1463
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0028 0.0424 0.0424
Brugia malayi Carboxylesterase family protein 0.0132 0.7688 0.8915
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0028 0.0424 0.0424
Echinococcus multilocularis acetylcholinesterase 0.0132 0.7688 0.7688
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.007 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0028 0.0424 0.0424
Schistosoma mansoni coup transcription factor 0.0028 0.0424 0.0424
Echinococcus multilocularis geminin 0.0165 1 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.007 0.007
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0028 0.0424 0.0424
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0028 0.0424 0.0424
Echinococcus granulosus jun protein 0.0081 0.4121 0.4121
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0091
Brugia malayi nuclear receptor NHR-88 0.0028 0.0424 0.0492
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0028 0.0424 0.0552
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.007 1
Echinococcus granulosus dna polymerase kappa 0.0023 0.007 0.007
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0028 0.5
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0424 0.0492
Brugia malayi ecdysteroid receptor 0.0028 0.0424 0.0492
Loa Loa (eye worm) hypothetical protein 0.0079 0.3966 0.5158
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.007 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0028 0.0424 0.0492
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0424 0.0492
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.007 0.0081
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0028 0.0424 0.0424
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0081 0.4121 0.4121
Brugia malayi steroid hormone receptor 0.0028 0.0424 0.0492
Echinococcus multilocularis carboxylesterase 5A 0.0132 0.7688 0.7688
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.007 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0028 0.0424 0.0552
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0028 0.0028
Brugia malayi hypothetical protein 0.0064 0.2901 0.3364
Toxoplasma gondii exonuclease III APE 0.0023 0.0028 0.5
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0028 0.0424 0.0492
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0424 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.007 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0028 0.0424 0.0492
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.007 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.007 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0028 0.0424 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.007 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0424 0.0552
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0028 0.0424 0.0492
Giardia lamblia DINP protein human, muc B family 0.0023 0.007 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0424 0.0492
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.007 0.007
Echinococcus multilocularis ecdysone induced protein 78C 0.0028 0.0424 0.0424
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0424 0.0492
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.007 0.0081
Loa Loa (eye worm) hypothetical protein 0.0028 0.0424 0.0552
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0145 0.8624 0.8624
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0028 0.0424 0.0424
Schistosoma mansoni RAR-like nuclear receptor 0.0028 0.0424 0.0424
Echinococcus multilocularis acetylcholinesterase 0.0132 0.7688 0.7688
Loa Loa (eye worm) hypothetical protein 0.0028 0.0424 0.0552
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0424 0.0492
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0028 0.0424 0.0552
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0028 0.0424 0.0492
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.007 1
Onchocerca volvulus 0.0028 0.0424 0.1463
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0028 0.4038
Echinococcus multilocularis jun protein 0.0081 0.4121 0.4121
Echinococcus multilocularis FTZ F1 alpha 0.0028 0.0424 0.0424
Echinococcus multilocularis dna polymerase kappa 0.0023 0.007 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0028 0.0424 0.0552
Schistosoma mansoni steroid hormone receptor ad4bp 0.0028 0.0424 0.0424
Trypanosoma brucei unspecified product 0.0023 0.007 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.007 1
Loa Loa (eye worm) acetylcholinesterase 1 0.0132 0.7688 1
Echinococcus multilocularis dna polymerase eta 0.0023 0.007 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.007 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0028 0.0424 0.0424
Brugia malayi hypothetical protein 0.0145 0.8624 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.007 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.007 0.0091
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.6584 0.8563
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0424 0.0492
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0028 0.5
Schistosoma mansoni DNA polymerase eta 0.0023 0.007 0.007
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0028 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0028 0.0424 0.0552
Onchocerca volvulus 0.0064 0.2901 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.007 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0028 0.0424 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.007 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.007 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0028 0.5
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.007 0.007
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0028 0.0424 0.0424
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.007 0.0048
Brugia malayi nuclear hormone receptor 0.0028 0.0424 0.0492
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0028 0.0424 0.0424
Leishmania major DNA polymerase eta, putative 0.0023 0.007 1
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.6584 0.8563
Loa Loa (eye worm) carboxylesterase 0.0132 0.7688 1
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0424 0.0424
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0081 0.4121 0.4121
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.007 1
Echinococcus granulosus FTZ F1 alpha 0.0028 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0028 0.0424 0.0552
Schistosoma mansoni hypothetical protein 0.0145 0.8624 0.8624
Brugia malayi photoreceptor-specific nuclear receptor 0.0028 0.0424 0.0492
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0028 0.0424 0.1463

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.8913 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.5119 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.4668 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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