Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0281 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.015 | 0.4363 | 0.2201 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0281 | 1 | 1 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.015 | 0.4363 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.4363 | 0.2201 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0281 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0281 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.4363 | 0.2201 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.015 | 0.4363 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.015 | 0.4363 | 0.2201 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.015 | 0.4363 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0113 | 0.2772 | 0.5 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.015 | 0.4363 | 1 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.015 | 0.4363 | 0.2201 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0113 | 0.2772 | 0.2772 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0281 | 1 | 1 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0281 | 1 | 1 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0049 | 0 | 0.5 |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.015 | 0.4363 | 1 |
Onchocerca volvulus | 0.015 | 0.4363 | 1 | |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.0281 | 1 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0113 | 0.2772 | 0.2772 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.015 | 0.4363 | 0.2201 |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.015 | 0.4363 | 1 |
Entamoeba histolytica | 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein | 0.015 | 0.4363 | 0.4363 |
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.015 | 0.4363 | 0.5 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0281 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.015 | 0.4363 | 0.4363 |
Plasmodium vivax | polyprenol reductase, putative | 0.015 | 0.4363 | 0.5 |
Entamoeba histolytica | trans-2,3-enoyl-CoA reductase, putative | 0.015 | 0.4363 | 0.4363 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.015 | 0.4363 | 0.2201 |
Mycobacterium ulcerans | hypothetical protein | 0.0281 | 1 | 1 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.015 | 0.4363 | 0.2201 |
Plasmodium falciparum | polyprenol reductase, putative | 0.015 | 0.4363 | 0.5 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.015 | 0.4363 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.015 | 0.4363 | 0.2201 |
Schistosoma mansoni | glycogen phosphorylase | 0.0113 | 0.2772 | 0.6355 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.015 | 0.4363 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0113 | 0.2772 | 0.6355 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.0281 | 1 | 1 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.0281 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 3.2944 uM | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | ChEMBL. | No reference |
Potency (functional) | 3.6964 uM | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | ChEMBL. | No reference |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Plasmodium falciparum | ChEMBL23 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.