TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 338.42 | Formula: C21H24NO3+
H donors: 3 H acceptors: 2 LogP: 3.7 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: Oc1ccc(cc1)CC[NH2+]C[C@H](COc1cccc2c1cccc2)O
InChi: 1S/C21H23NO3/c23-18-10-8-16(9-11-18)12-13-22-14-19(24)15-25-21-7-3-5-17-4-1-2-6-20(17)21/h1-11,19,22-24H,12-15H2/p+1/t19-/m0/s1
InChiKey: VTSHCTOPRILGOD-IBGZPJMESA-O

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0016	0.0025	0.1008
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0024	0.0079	0.3167
Entamoeba histolytica	N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative	0.0049	0.0249	1
Giardia lamblia	Glucosamine-6-phosphate isomerase, putative	0.0049	0.0249	1
Echinococcus multilocularis	N acetylglucosaminyl phosphatidylinositol	0.0049	0.0249	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Echinococcus multilocularis	cathepsin L cysteine protease	0.0024	0.0079	0.3167
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0024	0.0079	0.3167
Plasmodium falciparum	dihydrolipoyl dehydrogenase, mitochondrial	0.0017	0.0031	0.1256
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0047	0.0237	0.9534
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0024	0.0079	0.3167
Schistosoma mansoni	N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase	0.0049	0.0249	0.2554
Onchocerca volvulus	Cathepsin L homolog	0.0024	0.0079	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0024	0.0079	0.3167
Echinococcus multilocularis	dihydrolipoamide dehydrogenase	0.0017	0.0031	0.1256
Entamoeba histolytica	cysteine proteinase, putative	0.0024	0.0079	0.3167
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Brugia malayi	hypothetical protein	0.0037	0.0169	0.678
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0047	0.0237	0.9534
Trypanosoma cruzi	cysteine peptidase, putative	0.0024	0.0079	0.3167
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0031	0.1256
Leishmania major	cathepsin L-like protease	0.0024	0.0079	0.2186
Onchocerca volvulus		0.0024	0.0079	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0024	0.0079	0.3167
Plasmodium vivax	glutathione reductase, putative	0.0049	0.0248	0.9969
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0031	0.1256
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0047	0.0237	0.9481
Leishmania major	cathepsin L-like protease	0.0024	0.0079	0.2186
Leishmania major	cathepsin L-like protease	0.0024	0.0079	0.2186
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Plasmodium vivax	dihydrolipoyl dehydrogenase, mitochondrial, putative	0.0017	0.0031	0.1256
Toxoplasma gondii	thioredoxin reductase	0.0049	0.0248	0.9964
Trypanosoma cruzi	trypanothione reductase, putative	0.0017	0.0031	0.1256
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0024	0.0079	0.3167
Echinococcus multilocularis	cathepsin L cysteine protease	0.0024	0.0079	0.3167
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0047	0.0237	0.9534
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0049	0.0249	0.0226
Onchocerca volvulus		0.0024	0.0079	1
Loa Loa (eye worm)	cysteine protease	0.0024	0.0079	0.2402
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0047	0.0237	0.9534
Entamoeba histolytica	hypothetical protein	0.0037	0.0169	0.678
Loa Loa (eye worm)	ctsf protein	0.0024	0.0079	0.2402
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0037	0.0169	0.678
Mycobacterium tuberculosis	Probable oxidoreductase	0.0124	0.0758	0.0754
Mycobacterium ulcerans	N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB	0.0049	0.0249	0.0218
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0124	0.0758	0.0754
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0031	0.1256
Brugia malayi	Cathepsin L-like precursor	0.0024	0.0079	0.3167
Entamoeba histolytica	glucosamine-6-phosphate isomerase, putative	0.0049	0.0249	1
Toxoplasma gondii	N-acetylglucosaminylphosphatidylinositol deacetylase	0.0049	0.0249	1
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0016	0.0025	0.1008
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Trypanosoma cruzi	cysteine peptidase, putative	0.0024	0.0079	0.3167
Echinococcus multilocularis	cysteine protease	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Leishmania major	cathepsin L-like protease	0.0024	0.0079	0.2186
Leishmania major	cathepsin L-like protease	0.0024	0.0079	0.2186
Brugia malayi	Thioredoxin reductase	0.0049	0.0248	0.9969
Trypanosoma brucei	N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase	0.0049	0.0249	1
Onchocerca volvulus		0.0024	0.0079	1
Entamoeba histolytica	hypothetical protein	0.0037	0.0169	0.678
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0047	0.0237	0.2435
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0037	0.0169	0.678
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0112	0.0673	0.0666
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0031	0.1256
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0049	0.0248	0.9969
Mycobacterium ulcerans	mycothiol conjugate amidase Mca	0.1488	1	1
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0024	0.0079	0.3167
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0024	0.0079	0.3167
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.0017	0.0031	0.5
Trichomonas vaginalis	glutathione reductase, putative	0.0017	0.0031	0.1256
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0024	0.0079	0.3167
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Mycobacterium leprae	PROBABLE NADH DEHYDROGENASE NDH	0.0112	0.0673	0.0435
Echinococcus granulosus	thioredoxin glutathione reductase	0.0049	0.0248	0.9969
Plasmodium vivax	vivapain-2	0.0024	0.0079	0.3167
Loa Loa (eye worm)	phosphatidylinositol glycan anchor biosynthesis protein	0.0049	0.0249	1
Plasmodium falciparum	glutathione reductase	0.0049	0.0248	0.9969
Plasmodium falciparum	thioredoxin reductase	0.0049	0.0248	0.9969
Entamoeba histolytica	hypothetical protein	0.0037	0.0169	0.678
Plasmodium vivax	vivapain-2	0.0024	0.0079	0.3167
Schistosoma mansoni	transcription factor LCR-F1	0.0037	0.0169	0.1731
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Trypanosoma cruzi	trypanothione reductase, putative	0.0049	0.0248	0.9969
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Leishmania major	trypanothione reductase	0.0049	0.0248	0.9964
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Brugia malayi	glutathione reductase	0.0049	0.0248	0.9969
Trypanosoma brucei	dihydrolipoyl dehydrogenase	0.0017	0.0031	0.1256
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0079	0.2402
Plasmodium falciparum	thioredoxin reductase	0.0017	0.0031	0.1256
Mycobacterium tuberculosis	N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase)	0.0049	0.0249	0.0226
Loa Loa (eye worm)	glutathione reductase	0.0049	0.0248	0.9965
Echinococcus granulosus	dihydrolipoamide dehydrogenase	0.0017	0.0031	0.1256
Echinococcus granulosus	cathepsin l1	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0124	0.0758	0.0754
Brugia malayi	alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase	0.0012	0.0001	0.0029
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0112	0.0673	0.0666
Plasmodium vivax	thioredoxin reductase, putative	0.0049	0.0248	0.9969
Plasmodium falciparum	N-acetylglucosaminylphosphatidylinositol deacetylase, putative	0.0049	0.0249	1
Plasmodium falciparum	dihydrolipoyl dehydrogenase, apicoplast	0.0017	0.0031	0.1256
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0024	0.0079	0.3167
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0112	0.0673	0.0666
Chlamydia trachomatis	dihydrolipoyl dehydrogenase	0.0017	0.0031	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0047	0.0237	0.2435
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0031	0.1256
Schistosoma mansoni	cathepsin F (C01 family)	0.0024	0.0079	0.0809
Trichomonas vaginalis	glucosamine-6-phosphate isomerase, putative	0.0049	0.0249	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0024	0.0079	0.3167
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Echinococcus granulosus	N acetylglucosaminyl phosphatidylinositol	0.0049	0.0249	1
Plasmodium vivax	dihydrolipoyl dehydrogenase, apicoplast, putative	0.0017	0.0031	0.1256
Plasmodium vivax	N-acetylglucosaminylphosphatidylinositol deacetylase, putative	0.0049	0.0249	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0047	0.0237	0.2435
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0024	0.0079	0.2402
Entamoeba histolytica	hypothetical protein	0.0037	0.0169	0.678
Brugia malayi	Cathepsin L-like precursor	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Trypanosoma cruzi	cruzipain precursor, putative	0.0024	0.0079	0.3167
Echinococcus multilocularis	cysteine protease	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Brugia malayi	Cathepsin L-like precursor	0.0024	0.0079	0.3167
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0024	0.0079	0.2402
Leishmania major	cysteine peptidase A (CPA)	0.0024	0.0079	0.2186
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0017	0.0031	0.1256
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0047	0.0237	0.9534
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0124	0.0758	0.0522
Brugia malayi	Cathepsin L-like precursor	0.0024	0.0079	0.3167
Onchocerca volvulus		0.0024	0.0079	1
Entamoeba histolytica	cysteine proteinase, putative	0.0024	0.0079	0.3167
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.0017	0.0031	0.5
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Loa Loa (eye worm)	fibroinase	0.0024	0.0079	0.2402
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0025	0.1008
Loa Loa (eye worm)	thioredoxin reductase	0.0049	0.0248	0.9965
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0024	0.0079	0.3167
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0024	0.0079	0.3167
Trypanosoma cruzi	N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative	0.0049	0.0249	1
Brugia malayi	Cathepsin L-like precursor	0.0024	0.0079	0.3167
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0017	0.0031	0.1256
Brugia malayi	dihydrolipoyl dehydrogenase, mitochondrial precursor, putative	0.0017	0.0031	0.1256
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0017	0.0031	0.1256
Treponema pallidum	NADH oxidase	0.0017	0.0031	0.5
Entamoeba histolytica	cysteine proteinase, putative	0.0016	0.0025	0.1008
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0024	0.0079	0.3167
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0017	0.0031	0.1256
Leishmania major	N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase	0.0049	0.0249	1
Brugia malayi	Uncharacterized LmbE-like protein, COG2120 containing protein	0.0049	0.0249	1
Schistosoma mansoni	hypothetical protein	0.0037	0.0169	0.1731
Toxoplasma gondii	cathepsin CPL	0.0024	0.0079	0.2186
Trypanosoma brucei	dihydrolipoamide dehydrogenase, point mutation	0.0017	0.0031	0.1256
Plasmodium falciparum	glutathione reductase	0.0017	0.0031	0.1256
Brugia malayi	Cathepsin L-like precursor	0.0016	0.0025	0.1008
Brugia malayi	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein	0.0012	0.0001	0.0029
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0024	0.0079	0.3167
Brugia malayi	Cathepsin L-like precursor	0.0024	0.0079	0.3167
Leishmania major	cathepsin L-like protease	0.0024	0.0079	0.2186
Entamoeba histolytica	cysteine protease, putative	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0024	0.0079	0.3167
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Trypanosoma cruzi	N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative	0.0049	0.0249	1
Trypanosoma brucei	trypanothione reductase	0.0049	0.0248	0.9969
Onchocerca volvulus		0.0024	0.0079	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0016	0.0025	0.0257
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0016	0.0025	0.1008
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0024	0.0079	0.3167
Mycobacterium tuberculosis	Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase)	0.1439	0.9667	1
Onchocerca volvulus	Cathepsin L homolog	0.0024	0.0079	1
Trichomonas vaginalis	mercuric reductase, putative	0.0017	0.0031	0.1256
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0024	0.0079	0.3167
Mycobacterium tuberculosis	Probable dehydrogenase	0.0112	0.0673	0.0666
Leishmania major	cathepsin L-like protease	0.0024	0.0079	0.2186
Mycobacterium tuberculosis	Probable reductase	0.0112	0.0673	0.0666
Leishmania major	cathepsin L-like protease	0.0024	0.0079	0.2186
Brugia malayi	Papain family cysteine protease containing protein	0.0024	0.0079	0.3167
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0112	0.0673	0.0666
Trypanosoma cruzi	cysteine peptidase, putative	0.0024	0.0079	0.3167
Echinococcus granulosus	cathepsin l1	0.0016	0.0025	0.1008
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0049	0.0248	0.0225
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0024	0.0079	0.3167
Schistosoma mansoni	cathepsin F (C01 family)	0.0024	0.0079	0.0809
Onchocerca volvulus		0.0024	0.0079	1
Onchocerca volvulus		0.0024	0.0079	1
Brugia malayi	Cathepsin L-like precursor	0.0016	0.0025	0.1008
Onchocerca volvulus	Cathepsin F homolog	0.0024	0.0079	1
Schistosoma mansoni	dihydrolipoamide dehydrogenase	0.0017	0.0031	0.0321
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0017	0.0031	0.1256
Brugia malayi	cathepsin L-like precursor	0.0016	0.0025	0.1008

Activities

Activity type	Activity value	Assay description	Source	Reference
Delta G (binding)	= -10.93	Free energy of binding to turkey erythrocyte beta receptor	ChEMBL.	3005570

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: 258305

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 159611