Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0037 | 0.3315 | 0.3315 |
Brugia malayi | notch-like transmembrane receptor | 0.0025 | 0.0565 | 0.0565 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0035 | 0.2751 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | notch protein | 0.0025 | 0.0565 | 0.0565 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0041 | 0.4103 | 0.375 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0037 | 0.3315 | 0.2915 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Echinococcus granulosus | Tolloid protein 1 | 0.0067 | 1 | 1 |
Echinococcus granulosus | laminin | 0.0067 | 1 | 1 |
Brugia malayi | Delta serrate ligand family protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Schistosoma mansoni | egf-like domain protein | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
Brugia malayi | Muscle positioning protein 4 | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0037 | 0.3315 | 0.2915 |
Brugia malayi | EGF-like domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Onchocerca volvulus | Arrow homolog | 0.0067 | 1 | 1 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0037 | 0.3315 | 0.3315 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Brugia malayi | EGF-like domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0067 | 1 | 1 |
Echinococcus multilocularis | laminin | 0.0067 | 1 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Brugia malayi | Fibulin-1 precursor | 0.0067 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Brugia malayi | EGF-like domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Brugia malayi | EGF-like domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | Notch2 | 0.0025 | 0.0565 | 0.0565 |
Giardia lamblia | High cysteine protein | 0.0025 | 0.0565 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Echinococcus multilocularis | fibrillin 1 | 0.0067 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Brugia malayi | Cadherin domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0035 | 0.2751 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0565 | 0.0565 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0041 | 0.4103 | 0.375 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0067 | 1 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0025 | 0.0565 | 0.0565 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0067 | 1 | 1 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2183 | 0.2183 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.