Detailed information for compound 1607261

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 358.392 | Formula: C18H22N4O4
  • H donors: 4 H acceptors: 6 LogP: 1.73 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc2c(c1)c(NC(CO)(CO)C)c1c(n2)nc(nc1C)O
  • InChi: 1S/C18H22N4O4/c1-4-26-11-5-6-13-12(7-11)15(22-18(3,8-23)9-24)14-10(2)19-17(25)21-16(14)20-13/h5-7,23-24H,4,8-9H2,1-3H3,(H2,19,20,21,22,25)
  • InChiKey: KGOJPEJFYLHNCM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0037 0.1748 0.186
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Trichomonas vaginalis heat shock protein, putative 0.0023 0.0714 0.0722
Trypanosoma brucei heat shock protein, putative 0.004 0.1926 1
Brugia malayi Endoplasmin precursor 0.004 0.1926 0.2107
Trypanosoma brucei PAB1-binding protein , putative 0.002 0.0501 0.2372
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0022 0.0605 0.0109
Plasmodium vivax endoplasmin, putative 0.004 0.1926 0.15
Brugia malayi ecdysteroid receptor 0.0025 0.0865 0.0946
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Schistosoma mansoni tar DNA-binding protein 0.0046 0.2402 0.2468
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0037 0.1748 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0025 0.0865 0.0888
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0025 0.0865 0.0888
Loa Loa (eye worm) hypothetical protein 0.0025 0.0865 0.0946
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0025 0.0865 0.0946
Trichomonas vaginalis endoplasmin, putative 0.0029 0.1132 0.1182
Trichomonas vaginalis macrophage migration inhibitory factor, mif, putative 0.0139 0.9141 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0025 0.0865 0.0946
Trypanosoma brucei heat shock protein, putative 0.004 0.1926 1
Schistosoma mansoni thyroid hormone receptor 0.0025 0.0865 0.0888
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0058 0.006
Echinococcus granulosus ecdysone induced protein 78C 0.0025 0.0865 0.0888
Trichomonas vaginalis heat shock protein, putative 0.0037 0.1748 0.186
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0064
Schistosoma mansoni tar DNA-binding protein 0.0046 0.2402 0.2468
Schistosoma mansoni endoplasmin 0.004 0.1926 0.1978
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0025 0.0865 0.0946
Echinococcus granulosus dna polymerase kappa 0.0014 0.0058 0.006
Trichomonas vaginalis heat shock protein, putative 0.0029 0.1132 0.1182
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0025 0.0865 0.0946
Entamoeba histolytica heat shock protein 90, putative 0.004 0.1926 0.2056
Echinococcus granulosus tar DNA binding protein 0.0046 0.2402 0.2468
Toxoplasma gondii heat shock protein 75, putative 0.0026 0.0954 0.0477
Schistosoma mansoni coup transcription factor 0.0025 0.0865 0.0888
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0022 0.0605 0.0602
Echinococcus granulosus geminin 0.0147 0.9734 1
Trypanosoma cruzi Heat shock protein 83, putative 0.004 0.1926 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0025 0.0865 0.0946
Schistosoma mansoni endoplasmin 0.004 0.1926 0.1978
Echinococcus multilocularis endoplasmin 0.0037 0.1748 0.1796
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.1508 0.7761
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0025 0.0865 0.0888
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0025 0.0865 0.0888
Trypanosoma cruzi heat shock protein, putative 0.0026 0.0954 0.4798
Mycobacterium ulcerans heat shock protein 90 0.0037 0.1748 1
Loa Loa (eye worm) heat shock protein 90 0.004 0.1926 0.2107
Echinococcus multilocularis FTZ F1 alpha 0.0025 0.0865 0.0888
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0025 0.0865 0.0888
Schistosoma mansoni tar DNA-binding protein 0.0046 0.2402 0.2468
Schistosoma mansoni steroid hormone receptor ad4bp 0.0025 0.0865 0.0888
Schistosoma mansoni heat shock protein 0.004 0.1926 0.1978
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0025 0.0865 0.0888
Schistosoma mansoni RAR-like nuclear receptor 0.0025 0.0865 0.0888
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0501 0.2372
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0605 0.0622
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0058 0.006
Echinococcus multilocularis dna polymerase eta 0.0014 0.0058 0.006
Giardia lamblia Grp94/Hsp90 0.0037 0.1748 0.186
Plasmodium vivax heat shock protein 90, putative 0.0026 0.0954 0.0477
Loa Loa (eye worm) endoplasmin 0.004 0.1926 0.2107
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0025 0.0865 0.0888
Leishmania major hypothetical protein, conserved 0.002 0.0501 0.0488
Echinococcus granulosus FTZ F1 alpha 0.0025 0.0865 0.0888
Loa Loa (eye worm) macrophage migration inhibitory factor 0.0139 0.9141 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0025 0.0865 0.0888
Loa Loa (eye worm) hypothetical protein 0.0025 0.0865 0.0946
Toxoplasma gondii macrophage migration inhibitory factor, putative 0.0139 0.9141 0.9095
Loa Loa (eye worm) hypothetical protein 0.0025 0.0865 0.0946
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0022 0.0605 0.0622
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0022 0.0605 0.2927
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Brugia malayi nuclear receptor NHR-88 0.0025 0.0865 0.0946
Brugia malayi nuclear hormone receptor 0.0025 0.0865 0.0946
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0025 0.0865 0.0946
Trypanosoma brucei heat shock protein, putative 0.004 0.1926 1
Giardia lamblia Heat shock protein HSP 90-alpha 0.004 0.1926 0.2056
Trypanosoma brucei heat shock protein 90, putative 0.004 0.1926 1
Brugia malayi heat shock protein 90 0.004 0.1926 0.2107
Brugia malayi RNA binding protein 0.0046 0.2402 0.2628
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Echinococcus multilocularis tar DNA binding protein 0.0046 0.2402 0.2468
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0025 0.0865 0.0946
Brugia malayi hypothetical protein 0.002 0.0501 0.0548
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0025 0.0865 0.0888
Echinococcus multilocularis heat shock protein 90 0.0034 0.1508 0.1549
Brugia malayi steroid hormone receptor 0.0025 0.0865 0.0946
Plasmodium vivax heat shock protein, putative 0.0151 1 1
Plasmodium vivax macrophage migration inhibitory factor, putative 0.0139 0.9141 0.9095
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.1508 0.1596
Giardia lamblia TCP-1 chaperonin subunit beta 0.0022 0.0605 0.0602
Plasmodium falciparum heat shock protein 90, putative 0.0023 0.0714 0.0224
Trypanosoma brucei heat shock protein 90, putative 0.004 0.1926 1
Leishmania major heat shock protein, putative 0.0026 0.0954 0.0986
Schistosoma mansoni tar DNA-binding protein 0.0046 0.2402 0.2468
Trichomonas vaginalis chaperonin, putative 0.0022 0.0605 0.0602
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0605 0.0622
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0026 0.0954 0.098
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0865 0.0888
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0025 0.0865 0.0946
Brugia malayi Hsp90 protein 0.0026 0.0954 0.1044
Trypanosoma brucei heat shock protein, putative 0.004 0.1926 1
Trypanosoma brucei heat shock protein, putative 0.004 0.1926 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0865 0.0888
Echinococcus granulosus heat shock protein 0.004 0.1926 0.1978
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0865 0.0888
Schistosoma mansoni retinoic acid receptor RXR 0.0025 0.0865 0.0888
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Brugia malayi TAR-binding protein 0.0046 0.2402 0.2628
Schistosoma mansoni heat shock protein 0.0026 0.0954 0.098
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Loa Loa (eye worm) steroid hormone receptor 0.0025 0.0865 0.0946
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0022 0.0605 0.2927
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0025 0.0865 0.0888
Loa Loa (eye worm) macrophage migration inhibitory factor 2 0.0059 0.3344 0.3659
Schistosoma mansoni hypothetical protein 0.0147 0.9734 1
Schistosoma mansoni thyroid hormone receptor 0.0025 0.0865 0.0888
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0022 0.0605 0.0602
Toxoplasma gondii heat shock protein HSP90 0.004 0.1926 0.15
Brugia malayi T-complex protein 1, beta subunit 0.0022 0.0605 0.0662
Trypanosoma brucei heat shock protein, putative 0.004 0.1926 1
Loa Loa (eye worm) heat shock protein 75 0.0026 0.0954 0.1044
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0026 0.0954 0.0986
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0865 0.0946
Loa Loa (eye worm) hypothetical protein 0.0025 0.0865 0.0946
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0058 0.006
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0025 0.0865 0.0888
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0022 0.0605 0.0622
Loa Loa (eye worm) T-complex protein 1 0.0022 0.0605 0.0662
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0026 0.0954 0.098
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0034 0.1508 0.1549
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0025 0.0865 0.0946
Schistosoma mansoni tar DNA-binding protein 0.0046 0.2402 0.2468
Loa Loa (eye worm) hypothetical protein 0.002 0.0501 0.0548
Echinococcus multilocularis geminin 0.0147 0.9734 1
Brugia malayi T-complex protein 1, beta subunit 0.0022 0.0605 0.0662
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0025 0.0865 0.0946
Schistosoma mansoni hypothetical protein 0.0147 0.9734 1
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0046 0.2402 0.2628
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0865 0.0888
Brugia malayi Bm-MIF-1, identical 0.0139 0.9141 1
Trypanosoma cruzi heat shock protein 85, putative 0.004 0.1926 1
Trypanosoma brucei heat shock protein, putative 0.004 0.1926 1
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0022 0.0605 0.0622
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0025 0.0865 0.0946
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0037 0.1748 0.5
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0025 0.0865 0.0946
Brugia malayi Steroid receptor seven-up type 2 0.0025 0.0865 0.0946
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0058 0.0064
Plasmodium vivax heat shock protein 86, putative 0.004 0.1926 0.15
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Echinococcus multilocularis heat shock protein 0.004 0.1926 0.1978
Leishmania major macrophage migration inhibitory factor-like protein 0.0139 0.9141 1
Leishmania major macrophage migration inhibitory factor-like protein 0.0139 0.9141 1
Brugia malayi RNA recognition motif domain containing protein 0.0046 0.2402 0.2628
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Trypanosoma cruzi heat shock protein 90, putative 0.0017 0.0243 0.099
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0025 0.0865 0.0946
Trichomonas vaginalis heat shock protein, putative 0.004 0.1926 0.2056
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0058 0.006
Plasmodium falciparum T-complex protein 1 subunit beta 0.0022 0.0605 0.0109
Trypanosoma cruzi heat shock protein 85, putative 0.004 0.1926 1
Trypanosoma cruzi heat shock protein 85, putative 0.004 0.1926 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0865 0.0946
Schistosoma mansoni heat shock protein 0.004 0.1926 0.1978
Trypanosoma brucei heat shock protein 84, putative 0.0026 0.0954 0.4798
Loa Loa (eye worm) TAR-binding protein 0.0046 0.2402 0.2628
Trypanosoma cruzi heat shock protein 90, putative 0.004 0.1926 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0025 0.0865 0.0946
Echinococcus multilocularis dna polymerase kappa 0.0014 0.0058 0.006
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0058 0.0064
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0025 0.0865 0.0888
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0026 0.0954 1
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0501 0.2372
Loa Loa (eye worm) hypothetical protein 0.0025 0.0865 0.0946
Treponema pallidum heat shock protein 90 0.0037 0.1748 0.5
Loa Loa (eye worm) RNA binding protein 0.0046 0.2402 0.2628
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0865 0.0888
Entamoeba histolytica heat shock protein 90, putative 0.004 0.1926 0.2056
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0025 0.0865 0.0946
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0865 0.0888
Loa Loa (eye worm) macrophage migration inhibitory factor 2 0.0059 0.3344 0.3659
Plasmodium falciparum endoplasmin, putative 0.0029 0.1132 0.0664
Echinococcus multilocularis ecdysone induced protein 78C 0.0025 0.0865 0.0888
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0025 0.0865 0.0888
Trichomonas vaginalis heat shock protein, putative 0.0037 0.1748 0.186
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Loa Loa (eye worm) hypothetical protein 0.0025 0.0865 0.0946
Leishmania major T-complex protein 1, beta subunit, putative 0.0022 0.0605 0.0602
Plasmodium falciparum heat shock protein 90 0.004 0.1926 0.15
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0025 0.0865 0.0946
Echinococcus granulosus dna polymerase eta 0.0014 0.0058 0.006
Echinococcus multilocularis heat shock protein 90 0.004 0.1926 0.1978
Trypanosoma brucei heat shock protein, putative 0.004 0.1926 1
Plasmodium falciparum macrophage migration inhibitory factor 0.0139 0.9141 0.9095
Echinococcus granulosus endoplasmin 0.0037 0.1748 0.1796
Echinococcus granulosus heat shock protein 90 0.004 0.1926 0.1978
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0025 0.0865 0.0946
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0025 0.0865 0.0946
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.1508 0.7761
Loa Loa (eye worm) hypothetical protein 0.0025 0.0865 0.0946
Toxoplasma gondii Hsp90 domain-containing protein 0.0151 1 1
Entamoeba histolytica macrophage migration inhibitory factor-like protein 0.0139 0.9141 1
Trichomonas vaginalis heat shock protein, putative 0.0034 0.1508 0.1596
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0025 0.0865 0.0946
Leishmania major heat shock protein 83-1 0.004 0.1926 0.2056
Trypanosoma brucei Heat shock protein 83, putative 0.004 0.1926 1
Trichomonas vaginalis conserved hypothetical protein 0.0139 0.9141 1
Toxoplasma gondii t-complex protein beta subunit 0.0022 0.0605 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0025 0.0865 0.0946
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0058 0.0064
Toxoplasma gondii heat shock protein 90, putative 0.004 0.1926 0.15
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0025 0.0865 0.0888
Giardia lamblia Macrophage migration inhibitory factor 0.0139 0.9141 1
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0037 0.1748 0.5
Echinococcus granulosus heat shock protein 90 0.0034 0.1508 0.1549
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0025 0.0865 0.0888
Brugia malayi photoreceptor-specific nuclear receptor 0.0025 0.0865 0.0946
Schistosoma mansoni DNA polymerase eta 0.0014 0.0058 0.006

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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