Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | thioredoxin reductase, putative | 0.0099 | 0.1859 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0978 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0192 | 0.5343 | 0.9201 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0925 | 0.1724 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0193 | 0.5365 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0091 | 0.1548 | 0.1252 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0091 | 0.1548 | 0.2406 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0925 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.0556 | 0.1037 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0193 | 0.5365 | 0.5203 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0226 | 0.6623 | 0.8749 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0556 | 0.04 |
Brugia malayi | ecdysone receptor | 0.0091 | 0.1548 | 0.2223 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0193 | 0.5365 | 0.9243 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0193 | 0.5365 | 0.5203 |
Schistosoma mansoni | thyroid hormone receptor | 0.0193 | 0.5365 | 0.5203 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0252 | 0.757 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0193 | 0.5365 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0193 | 0.5365 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0102 | 0.1957 | 0.2975 |
Schistosoma mansoni | nuclear hormone receptor | 0.0091 | 0.1548 | 0.1252 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0091 | 0.1548 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.5365 | 0.9243 |
Onchocerca volvulus | 0.0091 | 0.1548 | 0.2406 | |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0193 | 0.5365 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0076 | 0.0978 | 0.1292 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0091 | 0.1548 | 0.2223 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0226 | 0.6623 | 0.8749 |
Brugia malayi | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1957 | 0.2975 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0102 | 0.1957 | 0.2975 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0925 | 0.0606 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0193 | 0.5365 | 0.9243 |
Plasmodium vivax | glutathione reductase, putative | 0.0099 | 0.1859 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0091 | 0.1548 | 0.1252 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0193 | 0.5365 | 0.5203 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0091 | 0.1548 | 0.2223 |
Schistosoma mansoni | nuclear receptor | 0.0091 | 0.1548 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0925 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0925 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0978 | 0.1174 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0193 | 0.5365 | 0.9243 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0925 | 0.1077 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0126 | 0.2856 | 0.4628 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0193 | 0.5365 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0193 | 0.5365 | 0.9243 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0082 | 0.12 | 0.2237 |
Onchocerca volvulus | 0.0193 | 0.5365 | 1 | |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0193 | 0.5365 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0153 | 0.3862 | 0.3647 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0193 | 0.5365 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0193 | 0.5365 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0099 | 0.1859 | 0.5 |
Brugia malayi | nuclear hormone receptor | 0.0091 | 0.1548 | 0.2223 |
Plasmodium falciparum | thioredoxin reductase | 0.0099 | 0.1859 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0102 | 0.1957 | 0.3647 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0193 | 0.5365 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0226 | 0.6623 | 0.8749 |
Plasmodium falciparum | glutathione reductase | 0.0099 | 0.1859 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0252 | 0.757 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0193 | 0.5365 | 1 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0076 | 0.0978 | 0.1822 |
Schistosoma mansoni | coup transcription factor | 0.0193 | 0.5365 | 0.5203 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0091 | 0.1548 | 0.2886 |
Giardia lamblia | PHD finger protein 15 | 0.0059 | 0.0339 | 0.5 |
Brugia malayi | glutathione reductase | 0.0099 | 0.1859 | 0.2794 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0193 | 0.5365 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0099 | 0.1859 | 0.2794 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | DR-78 | 0.0091 | 0.1548 | 0.2223 |
Mycobacterium tuberculosis | Probable reductase | 0.0226 | 0.6623 | 0.8749 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0193 | 0.5365 | 0.9243 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0091 | 0.1548 | 0.1252 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0064 | 0.0556 | 0.04 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0204 | 0.5777 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0091 | 0.1548 | 0.2886 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0925 | 0.0606 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0059 | 0.0339 | 0.0632 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0925 | 0.5 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0091 | 0.1548 | 0.2886 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0193 | 0.5365 | 0.9243 |
Echinococcus granulosus | FTZ F1 alpha | 0.0193 | 0.5365 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0193 | 0.5365 | 0.5203 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0091 | 0.1548 | 0.2886 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3361 | 0.5556 |
Brugia malayi | ecdysteroid receptor | 0.0193 | 0.5365 | 0.9243 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0076 | 0.0978 | 0.4202 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0193 | 0.5365 | 0.9243 |
Brugia malayi | hypothetical protein | 0.0102 | 0.1957 | 0.2975 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0193 | 0.5365 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0091 | 0.1548 | 0.2886 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0091 | 0.1548 | 0.2886 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0193 | 0.5365 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0193 | 0.5365 | 0.9243 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0226 | 0.6623 | 0.8749 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0193 | 0.5365 | 0.9243 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0102 | 0.1957 | 0.1675 |
Loa Loa (eye worm) | glutathione reductase | 0.0099 | 0.1859 | 0.2794 |
Echinococcus granulosus | jumonji domain containing protein | 0.0082 | 0.12 | 0.2237 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Brugia malayi | conserved hypotetical protein | 0.0091 | 0.1548 | 0.2223 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0252 | 0.757 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0071 | 0.0802 | 0.1494 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0193 | 0.5365 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Schistosoma mansoni | nuclear receptor | 0.0091 | 0.1548 | 0.1252 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.5365 | 0.9243 |
Echinococcus multilocularis | peregrin | 0.0059 | 0.0339 | 0.0632 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0091 | 0.1548 | 0.2886 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0556 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1957 | 0.2975 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0193 | 0.5365 | 0.5203 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0091 | 0.1548 | 0.2223 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0071 | 0.0802 | 0.0479 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0102 | 0.1957 | 0.1675 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0076 | 0.0978 | 0.0661 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.5777 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0978 | 0.5 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0192 | 0.5343 | 0.9958 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0193 | 0.5365 | 0.5203 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.0556 | 0.1037 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0126 | 0.2856 | 0.4628 |
Echinococcus granulosus | peregrin | 0.0059 | 0.0339 | 0.0632 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0102 | 0.1957 | 0.2975 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0102 | 0.1957 | 0.3647 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0099 | 0.1859 | 0.3464 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0091 | 0.1548 | 0.2406 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0192 | 0.5343 | 0.9958 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0204 | 0.5777 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0252 | 0.757 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0193 | 0.5365 | 0.9243 |
Schistosoma mansoni | nuclear hormone receptor | 0.0193 | 0.5365 | 0.5203 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.5365 | 0.9243 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0071 | 0.0802 | 0.0479 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0091 | 0.1548 | 0.2886 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0091 | 0.1548 | 0.2223 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0064 | 0.0556 | 0.04 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1957 | 0.2975 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0099 | 0.1859 | 0.3464 |
Toxoplasma gondii | thioredoxin reductase | 0.0099 | 0.1859 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0064 | 0.0556 | 0.1037 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0978 | 0.4202 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0193 | 0.5365 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Brugia malayi | nuclear receptor NHR-88 | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0099 | 0.1859 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0193 | 0.5365 | 0.9243 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0193 | 0.5365 | 0.5203 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0091 | 0.1548 | 0.2223 |
Echinococcus granulosus | GPCR family 2 | 0.0064 | 0.0556 | 0.1037 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0076 | 0.0978 | 0.1822 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0064 | 0.0556 | 0.04 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0091 | 0.1548 | 0.2223 |
Brugia malayi | nuclear receptor NHR-67 | 0.0091 | 0.1548 | 0.2223 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.0556 | 0.1037 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0925 | 0.1724 |
Brugia malayi | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0076 | 0.0978 | 0.4202 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0193 | 0.5365 | 0.9243 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.3361 | 0.3128 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0193 | 0.5365 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0226 | 0.6623 | 0.8749 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.0556 | 0.1037 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0556 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1548 | 0.2223 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0226 | 0.6623 | 0.8749 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0556 | 0.0225 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0091 | 0.1548 | 0.2886 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0099 | 0.1859 | 0.2456 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0076 | 0.0978 | 0.4202 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0193 | 0.5365 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0193 | 0.5365 | 0.9243 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0091 | 0.1548 | 0.2886 |
Brugia malayi | Probable ClpP-like protease | 0.0076 | 0.0978 | 0.1174 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0139 | 0.3361 | 0.5556 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0071 | 0.0802 | 0.0851 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0193 | 0.5365 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0099 | 0.1859 | 0.2794 |
Brugia malayi | jmjC domain containing protein | 0.0071 | 0.0802 | 0.0851 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0193 | 0.5365 | 0.9243 |
Brugia malayi | MH2 domain containing protein | 0.0126 | 0.2856 | 0.4628 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0978 | 0.5 |
Brugia malayi | tailless protein | 0.0091 | 0.1548 | 0.2223 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0091 | 0.1548 | 0.2886 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0091 | 0.1548 | 0.2223 |
Schistosoma mansoni | thyroid hormone receptor | 0.0193 | 0.5365 | 0.5203 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1957 | 0.2975 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0091 | 0.1548 | 0.2886 |
Brugia malayi | hypothetical protein | 0.0102 | 0.1957 | 0.2975 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0193 | 0.5365 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0193 | 0.5365 | 0.9243 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0204 | 0.5777 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0193 | 0.5365 | 0.9243 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0978 | 0.5 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0978 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1957 | 0.2975 |
Brugia malayi | nuclear receptor RXR | 0.0102 | 0.1957 | 0.2975 |
Brugia malayi | nuclear hormone receptor | 0.0193 | 0.5365 | 0.9243 |
Leishmania major | trypanothione reductase | 0.0099 | 0.1859 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0193 | 0.5365 | 0.9243 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0091 | 0.1548 | 0.2223 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0556 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.5365 | 0.9243 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0193 | 0.5365 | 0.9243 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0193 | 0.5365 | 0.9243 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0121 | 0.2681 | 0.4306 |
Brugia malayi | nuclear receptor NHR-88 | 0.0091 | 0.1548 | 0.2223 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0091 | 0.1548 | 0.2223 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0059 | 0.0339 | 0.0632 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.191 | 0.2889 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0193 | 0.5365 | 0.5203 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0978 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0193 | 0.5365 | 0.5203 |
Schistosoma mansoni | zinc finger protein | 0.0091 | 0.1548 | 0.1252 |
Brugia malayi | nuclear receptor RXR | 0.0091 | 0.1548 | 0.2223 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0071 | 0.0802 | 0.1494 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0193 | 0.5365 | 1 |
Onchocerca volvulus | 0.0091 | 0.1548 | 0.2406 | |
Brugia malayi | steroid hormone receptor | 0.0193 | 0.5365 | 0.9243 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 5.83 % | Activation of PPAR in human HepG2 cells at 10 ug/ml after 24 hrs by luciferase reporter gene assay relative to rosiglitazone | ChEMBL. | 22364952 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.