Detailed information for compound 1638479

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 332.439 | Formula: C22H24N2O
  • H donors: 0 H acceptors: 0 LogP: 3.58 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=C=CCN(Cc1cc2c(n1C)ccc(c2)OCc1ccccc1)C
  • InChi: 1S/C22H24N2O/c1-4-5-13-23(2)16-20-14-19-15-21(11-12-22(19)24(20)3)25-17-18-9-7-6-8-10-18/h5-12,14-15H,1,13,16-17H2,2-3H3
  • InChiKey: SCWQHRXSENXPJQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7352 0.7346
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0062 0.0334 0.031
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0062 0.0334 0.0302
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0768 0.7894 0.7822
Brugia malayi FAT domain containing protein 0.0141 0.1178 0.1149
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0086 0.0052
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0062 0.0334 0.031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7352 0.7346
Trichomonas vaginalis PIKK family atypical protein kinase 0.0647 0.6598 0.659
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0062 0.0334 0.031
Entamoeba histolytica protein kinase rad3, putative 0.0182 0.1622 0.1594
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0062 0.0334 0.0302
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0964 1 1
Loa Loa (eye worm) hypothetical protein 0.0203 0.1845 0.1845
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0062 0.0334 0.0302
Schistosoma mansoni hypothetical protein 0.0141 0.1178 0.1149
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0062 0.0334 0.0302
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0062 0.0334 0.0302
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0806 0.0782
Echinococcus multilocularis 0.0062 0.0334 0.0302
Echinococcus granulosus serine protein kinase ATM 0.0182 0.1622 0.1594
Mycobacterium leprae conserved hypothetical protein 0.0062 0.0334 0.5
Trypanosoma brucei adenosine kinase, putative 0.0084 0.0571 0.0245
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0051 0.0017
Schistosoma mansoni adenosine kinase 0.0084 0.0571 0.054
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0062 0.0334 0.0302
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0964 1 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0964 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0182 0.1622 0.1601
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0334 0.031
Trypanosoma brucei rac serine-threonine kinase, putative 0.0106 0.0806 0.0488
Mycobacterium tuberculosis Conserved hypothetical protein 0.0062 0.0334 0.5
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0955 0.0932
Brugia malayi Protein kinase domain containing protein 0.0106 0.0806 0.0775
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0034
Entamoeba histolytica hypothetical protein 0.0062 0.0334 0.0302
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0086 0.0052
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0034 0.0008
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0768 0.7894 0.7822
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0964 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0203 0.1845 0.1824
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7352 0.7346
Loa Loa (eye worm) phosphatidylinositol 3 0.0062 0.0334 0.0334
Trichomonas vaginalis PIKK family atypical protein kinase 0.0576 0.5842 0.5831
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0062 0.0334 0.031
Trichomonas vaginalis PIKK family atypical protein kinase 0.052 0.5238 0.5226
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0062 0.0334 0.0302
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7352 0.7346
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0062 0.0334 0.0302
Entamoeba histolytica protein kinase 2, putative 0.0066 0.0377 0.0345
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0066 0.0377 0.0345
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0062 0.0334 0.0302
Trichomonas vaginalis PIKK family atypical protein kinase 0.0964 1 1
Trypanosoma cruzi Protein kinase B 0.0073 0.0448 0.0117
Entamoeba histolytica PH domain containing protein kinase, putative 0.0073 0.0448 0.0415
Trichomonas vaginalis PIKK family atypical protein kinase 0.0323 0.3133 0.3115
Loa Loa (eye worm) phosphatidylinositol 3 0.0062 0.0334 0.0334
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7352 0.7346
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0182 0.1622 0.1594
Trichomonas vaginalis PIKK family atypical protein kinase 0.012 0.0955 0.0932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0964 1 1
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0323 0.3133 0.2895
Echinococcus multilocularis rac serine:threonine kinase 0.0073 0.0448 0.0415
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0062 0.0334 0.0302
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0034 0.0008
Loa Loa (eye worm) AGC/PKN protein kinase 0.0034 0.0034 0.0034
Echinococcus multilocularis Zinc finger, PHD finger 0.0062 0.0334 0.0302
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0034 0.0034 0.0034
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0401 0.3959 0.375
Trypanosoma cruzi adenosine kinase, putative 0.0084 0.0571 0.0245
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0062 0.0334 0.0302
Trichomonas vaginalis conserved hypothetical protein 0.0141 0.1178 0.1156
Echinococcus granulosus nervana 2 0.0066 0.0369 0.0337
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0323 0.3133 0.311
Entamoeba histolytica hypothetical protein 0.0182 0.1622 0.1594
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0062 0.0334 0.0302
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0073 0.0448 0.0117
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0964 1 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0066 0.0377 0.0045
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0323 0.3133 0.2895
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0062 0.0334 0.0302
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0062 0.0334 0.031
Entamoeba histolytica hypothetical protein 0.0062 0.0334 0.0302
Toxoplasma gondii FATC domain-containing protein 0.0182 0.1622 0.1835
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0323 0.3133 0.311
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0182 0.1622 0.1332
Trichomonas vaginalis PIKK family atypical protein kinase 0.052 0.5238 0.5226
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0062 0.0334 0.0302
Trichomonas vaginalis PIKK family atypical protein kinase 0.0964 1 1
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0062 0.0334 0.0334
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0062 0.0334 0.0302
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0806 0.0782
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0062 0.0334 0.031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0767 0.7886 0.7881
Trichomonas vaginalis PIKK family atypical protein kinase 0.0521 0.5247 0.5235
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0062 0.0334 0.031
Echinococcus multilocularis serine protein kinase ATM 0.0182 0.1622 0.1594
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0062 0.0334 0.0302
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0062 0.0334 0.0302
Trypanosoma brucei adenosine kinase, putative 0.0084 0.0571 0.0245
Loa Loa (eye worm) phosphatidylinositol 3 0.0062 0.0334 0.0334
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0806 0.0782
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0062 0.0334 0.0302
Schistosoma mansoni adenosine kinase 0.0084 0.0571 0.054
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0062 0.0334 0.0302
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0066 0.0377 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7352 0.7346
Trichomonas vaginalis PIKK family atypical protein kinase 0.0182 0.1622 0.1601
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0806 0.0782
Echinococcus multilocularis Glutaredoxin protein 5 0.0066 0.0369 0.0337
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0062 0.0334 0.0302
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0182 0.1622 0.1332
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0062 0.0334 0.0302
Loa Loa (eye worm) hypothetical protein 0.0182 0.1622 0.1622
Trichomonas vaginalis PIKK family atypical protein kinase 0.0521 0.5247 0.5235
Toxoplasma gondii target of rapamycin (TOR), putative 0.0717 0.7352 1
Entamoeba histolytica protein kinase, putative 0.0106 0.0806 0.0775
Loa Loa (eye worm) hypothetical protein 0.0062 0.0334 0.0334
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0964 1 1
Onchocerca volvulus 0.0075 0.0468 1
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0066 0.0377 0.0345
Trichomonas vaginalis PIKK family atypical protein kinase 0.0323 0.3133 0.3115
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0062 0.0334 0.0302
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0182 0.1622 0.1332
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0062 0.0334 0.031
Giardia lamblia Kinase, AGC PKA 0.0066 0.0377 0.0045
Schistosoma mansoni serine/threonine-protein kinase 0.0073 0.0448 0.0415
Loa Loa (eye worm) hypothetical protein 0.0141 0.1178 0.1178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0521 0.5247 0.5235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0767 0.7886 0.7881
Echinococcus multilocularis nervana 2 0.0066 0.0369 0.0337
Giardia lamblia GTOR 0.0964 1 1
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0066 0.0377 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0323 0.3133 0.3133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0823 0.8489 0.8485
Loa Loa (eye worm) phosphatidylinositol 3 0.0062 0.0334 0.0334
Echinococcus granulosus serine threonine protein kinase nrc 0.0066 0.0377 0.0345
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0062 0.0334 0.0302
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0051 0.0017
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0456 0.4554 0.4366
Echinococcus multilocularis nervana 2 0.0066 0.0369 0.0337
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0062 0.0334 0.0302
Trichomonas vaginalis PIKK family atypical protein kinase 0.0767 0.7886 0.7881
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.01 0.0735 0.0735
Leishmania major adenosine kinase, putative 0.0084 0.0571 0.0245
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0062 0.0334 0.0302
Trichomonas vaginalis PIKK family atypical protein kinase 0.0323 0.3133 0.3115
Brugia malayi Adenosine kinase-like 0.0084 0.0571 0.054
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0182 0.1622 0.1594
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0964 1 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0964 1 1
Echinococcus granulosus serine/threonine protein kinase 0.0073 0.0448 0.0415
Echinococcus granulosus Glutaredoxin protein 5 0.0066 0.0369 0.0337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0259 0.244 0.2421
Entamoeba histolytica hypothetical protein 0.0062 0.0334 0.0302
Trichomonas vaginalis PIKK family atypical protein kinase 0.057 0.578 0.577
Trichomonas vaginalis AGC family protein kinase 0.0041 0.0104 0.0079
Loa Loa (eye worm) hypothetical protein 0.0197 0.1773 0.1773
Trichomonas vaginalis PIKK family atypical protein kinase 0.0626 0.6375 0.6366
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0806 0.0782
Loa Loa (eye worm) hypothetical protein 0.0062 0.0334 0.0334
Loa Loa (eye worm) phosphatidylinositol kinase 0.0062 0.0334 0.0334
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0062 0.0334 0.0302
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.012 0.0955 0.0642
Trichomonas vaginalis PIKK family atypical protein kinase 0.0323 0.3133 0.3115
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0062 0.0334 0.031
Brugia malayi p70 ribosomal S6 kinase beta 0.01 0.0735 0.0704
Trichomonas vaginalis PIKK family atypical protein kinase 0.0323 0.3133 0.3115
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0964 1 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0182 0.1622 0.1594
Trichomonas vaginalis PIKK family atypical protein kinase 0.0767 0.7886 0.7881
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0034 0.0034 0.0034
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0062 0.0334 0.0302
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0062 0.0334 0.0302
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0323 0.3133 0.2895
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0182 0.1622 0.1594
Toxoplasma gondii kinase, pfkB family protein 0.0084 0.0571 0.0338
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0062 0.0334 0.0302
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0034 0.0008
Leishmania major phosphatidylinositol 3-kinase, putative 0.0323 0.3133 0.2895
Echinococcus granulosus nervana 2 0.0066 0.0369 0.0337
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0141 0.1178 0.1149
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0323 0.3133 0.311
Trypanosoma cruzi adenosine kinase, putative 0.0084 0.0571 0.0245
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0062 0.0334 0.0302
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0062 0.0334 0.031
Loa Loa (eye worm) hypothetical protein 0.0084 0.0571 0.0571
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0964 1 1
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0062 0.0334 0.031
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0203 0.1845 0.2153
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0323 0.3133 0.2895
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0334 0.031
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0034 0.0034 0.0034
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0323 0.3133 0.311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0576 0.5842 0.5831
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0323 0.3133 0.2895
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0182 0.1622 0.1594
Echinococcus multilocularis adenosine kinase 0.0084 0.0571 0.054
Entamoeba histolytica PH domain containing protein kinase, putative 0.0073 0.0448 0.0415
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0964 1 1
Schistosoma mansoni serine/threonine-protein kinase 0.0073 0.0448 0.0415
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0062 0.0334 0.0302
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0062 0.0334 0.0302
Trichomonas vaginalis PIKK family atypical protein kinase 0.057 0.578 0.577
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0051 0.0051
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0062 0.0334 0.0302
Entamoeba histolytica hypothetical protein 0.0062 0.0334 0.0302
Trichomonas vaginalis PIKK family atypical protein kinase 0.052 0.5238 0.5226
Loa Loa (eye worm) AGC/NDR protein kinase 0.0034 0.0034 0.0034
Entamoeba histolytica protein kinase, putative 0.0106 0.0806 0.0775
Toxoplasma gondii AGC kinase 0.01 0.0735 0.0572
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0141 0.1178 0.1149
Trichomonas vaginalis PIKK family atypical protein kinase 0.0576 0.5842 0.5831
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0066 0.0369 0.0337
Loa Loa (eye worm) phosphatidylinositol 3 0.0062 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.012 0.0955 0.0955
Trypanosoma cruzi target of rapamycin kinase 3 0.0768 0.7894 0.7822
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0806 0.0782
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0062 0.0334 0.0302
Schistosoma mansoni fkbp-rapamycin associated protein 0.0182 0.1622 0.1594
Schistosoma mansoni hypothetical protein 0.0062 0.0334 0.0302
Trichomonas vaginalis AGC family protein kinase 0.0106 0.0806 0.0782
Trichomonas vaginalis PIKK family atypical protein kinase 0.0182 0.1622 0.1601
Echinococcus granulosus adenosine kinase 0.0084 0.0571 0.054
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0062 0.0334 0.031
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0062 0.0334 0.0302
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0034 0.0034 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0767 0.7886 0.7881
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0182 0.1622 0.1594
Trichomonas vaginalis PIKK family atypical protein kinase 0.0521 0.5247 0.5235
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0062 0.0334 0.0302
Loa Loa (eye worm) AGC/AKT protein kinase 0.0106 0.0806 0.0806
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0066 0.0369 0.0337
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0964 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0717 0.7352 0.7346
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0051 0.0017
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0062 0.0334 0.031
Entamoeba histolytica protein kinase, putative 0.01 0.0735 0.0704

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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