Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.5618 | 0.839 |
Giardia lamblia | Methionyl-tRNA synthetase | 0.0057 | 0.269 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0971 | 0.0971 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.3511 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0971 | 0.0971 |
Schistosoma mansoni | transient receptor potential channel | 0.0017 | 0.00000060783 | 0.00000060783 |
Echinococcus granulosus | methionyl tRNA synthetase cytoplasmic | 0.0022 | 0.0298 | 0.0298 |
Leishmania major | methionyl-tRNA synthetase, putative | 0.0057 | 0.269 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.1449 | 0.2164 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0971 | 0.145 |
Treponema pallidum | leucyl-tRNA synthetase | 0.0022 | 0.0298 | 0.5 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.0057 | 0.269 | 0.269 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.3511 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.00000060783 | 0.00000090764 |
Brugia malayi | protein ZK524.3 | 0.0022 | 0.0298 | 0.0444 |
Onchocerca volvulus | 0.0035 | 0.1213 | 0.7356 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0298 | 0.0444 |
Echinococcus granulosus | methionine tRNA synthetase | 0.0057 | 0.269 | 0.269 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.5618 | 0.839 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.00000060783 | 0.00000060783 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.3511 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0298 | 0.0444 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.00000060783 | 0.00000060783 |
Brugia malayi | MH2 domain containing protein | 0.0115 | 0.6697 | 1 |
Echinococcus multilocularis | methionine tRNA synthetase | 0.0057 | 0.269 | 0.269 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1449 | 0.2164 |
Brugia malayi | olfactory channel protein osm-9 | 0.0017 | 0.00000060783 | 0.00000090764 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0971 | 0.0971 |
Mycobacterium leprae | Probable methionyl-tRNA synthase MetS | 0.0057 | 0.269 | 0.5 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.00000060783 | 0.00000060783 |
Mycobacterium tuberculosis | Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) | 0.0057 | 0.269 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0971 | 0.0971 |
Echinococcus multilocularis | leucyl tRNA synthetase | 0.0022 | 0.0298 | 0.0298 |
Leishmania major | leucyl-tRNA synthetase, putative | 0.0022 | 0.0298 | 0.1106 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.1449 | 0.4129 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.00000060783 | 0.00000060783 |
Brugia malayi | methionyl-tRNA synthetase | 0.0057 | 0.269 | 0.4017 |
Trichomonas vaginalis | methionine-tRNA synthetase, putative | 0.0057 | 0.269 | 0.7663 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 1 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0115 | 0.6697 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0971 | 0.145 |
Echinococcus multilocularis | geminin | 0.0164 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0971 | 0.145 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.5618 | 0.839 |
Toxoplasma gondii | tRNA ligases class I (M) protein | 0.0022 | 0.0298 | 0.1106 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.5618 | 0.839 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.3511 | 0.3511 |
Loa Loa (eye worm) | tyrosyl-tRNA synthetase | 0.0035 | 0.1213 | 0.1811 |
Mycobacterium ulcerans | methionyl-tRNA synthetase | 0.0057 | 0.269 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.3511 | 0.3511 |
Trypanosoma brucei | methionyl-tRNA synthetase, putative | 0.0057 | 0.269 | 1 |
Schistosoma mansoni | leucyl-tRNA synthetase | 0.0022 | 0.0298 | 0.0298 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0298 | 0.0444 |
Loa Loa (eye worm) | methionyl-tRNA synthetase | 0.0057 | 0.269 | 0.4017 |
Schistosoma mansoni | transient receptor potential channel | 0.0017 | 0.00000060783 | 0.00000060783 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.3511 | 0.3511 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.00000060783 | 0.00000060783 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.3511 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.00000060783 | 0.00000090764 |
Chlamydia trachomatis | leucine--tRNA ligase | 0.0022 | 0.0298 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0971 | 0.0971 |
Trypanosoma cruzi | methionyl-tRNA synthetase, putative | 0.0057 | 0.269 | 1 |
Chlamydia trachomatis | methionine--tRNA ligase | 0.0022 | 0.0298 | 0.5 |
Plasmodium falciparum | methionine--tRNA ligase | 0.0057 | 0.269 | 1 |
Echinococcus multilocularis | methionyl tRNA synthetase, cytoplasmic | 0.0022 | 0.0298 | 0.0298 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.1649 | 0.4697 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0971 | 0.0971 |
Brugia malayi | methionyl-tRNA synthetase | 0.0022 | 0.0298 | 0.0444 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.00000060783 | 0.00000060783 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0881 | 0.1316 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0069 | 0.3511 | 0.5242 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.1449 | 0.8789 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.3511 | 0.3511 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0682 | 0.1942 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.3467 | 0.5178 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.1449 | 0.4129 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 1 | 1 |
Plasmodium vivax | methionine--tRNA ligase, putative | 0.0057 | 0.269 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0971 | 0.145 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.0022 | 0.0298 | 0.0298 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.3467 | 0.3467 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.1649 | 0.4697 |
Wolbachia endosymbiont of Brugia malayi | methionyl-tRNA synthetase | 0.0057 | 0.269 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.3467 | 0.5178 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0682 | 0.1942 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0971 | 0.0971 |
Entamoeba histolytica | methionyl-tRNA synthetase, putative | 0.0022 | 0.0298 | 0.5 |
Toxoplasma gondii | methionyl-tRNA synthetase | 0.0057 | 0.269 | 1 |
Treponema pallidum | methionyl-tRNA synthetase | 0.0022 | 0.0298 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0115 | 0.6697 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0069 | 0.3511 | 0.5242 |
Onchocerca volvulus | 0.003 | 0.0881 | 0.5345 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.00000060783 | 0.00000090764 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.1649 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0971 | 0.0971 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0971 | 0.0971 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0971 | 0.0971 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.