Detailed information for compound 1643884

Basic information

Technical information
  • TDR Targets ID: 1643884
  • Name: [(2R,3S,4R,5R)-5-[6-[[(1S)-2,3-dihydro-1H-ind en-1-yl]amino]purin-9-yl]-3,4-dihydroxyoxolan -2-yl]methyl sulfamate
  • MW: 462.48 | Formula: C19H22N6O6S
  • H donors: 4 H acceptors: 7 LogP: -0.44 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@@H]1[C@H](O)[C@H](O[C@H]1n1cnc2c1ncnc2N[C@H]1CCc2c1cccc2)COS(=O)(=O)N
  • InChi: 1S/C19H22N6O6S/c20-32(28,29)30-7-13-15(26)16(27)19(31-13)25-9-23-14-17(21-8-22-18(14)25)24-12-6-5-10-3-1-2-4-11(10)12/h1-4,8-9,12-13,15-16,19,26-27H,5-7H2,(H2,20,28,29)(H,21,22,24)/t12-,13+,15+,16+,19+/m0/s1
  • InChiKey: PGAMXUGSHMQFKD-BPAMBQHCSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-[[(1S)-indan-1-yl]amino]purin-9-yl]tetrahydrofuran-2-yl]methyl sulfamate
  • sulfamic acid [(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-[[(1S)-1-indanyl]amino]-9-purinyl]-2-tetrahydrofuranyl]methyl ester
  • sulfamic acid [(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-[[(1S)-indan-1-yl]amino]purin-9-yl]tetrahydrofuran-2-yl]methyl ester
  • [(2R,3S,4R,5R)-5-[6-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methyl sulfamate

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ubiquitin-like modifier activating enzyme 3 No references
Homo sapiens ubiquitin-like modifier activating enzyme 6 Starlite/ChEMBL References
Homo sapiens ubiquitin-like modifier activating enzyme 7 Starlite/ChEMBL References
Homo sapiens NEDD8 activating enzyme E1 subunit 1 Starlite/ChEMBL References
Homo sapiens SUMO1 activating enzyme subunit 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Babesia bovis conserved hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Echinococcus multilocularis ubiquitin modifier activating enzyme 6 Get druggable targets OG5_127070 All targets in OG5_127070
Cryptosporidium hominis ubiquitin-activating enzyme e1 Get druggable targets OG5_127070 All targets in OG5_127070
Leishmania braziliensis ubiquitin-activating enzyme e1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Trypanosoma brucei gambiense ubiquitin-activating enzyme e1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Plasmodium knowlesi ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Echinococcus multilocularis NEDD8 activating enzyme E1 catalytic subunit Get druggable targets OG5_128095 All targets in OG5_128095
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Candida albicans Required for activation of RUB1 Get druggable targets OG5_128412 All targets in OG5_128412
Babesia bovis ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Trypanosoma brucei NEDD8-activating enzyme E1 regulatory subunit, putative Get druggable targets OG5_128412 All targets in OG5_128412
Giardia lamblia Ubiquitin-conjugating enzyme E1 Get druggable targets OG5_127070 All targets in OG5_127070
Trypanosoma brucei ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Candida albicans ubiquitin-activating enzyme Get druggable targets OG5_127070 All targets in OG5_127070
Trypanosoma brucei NEDD8 activating enzyme subunit, putative Get druggable targets OG5_128095 All targets in OG5_128095
Leishmania braziliensis hypothetical protein, conserved Get druggable targets OG5_128412 All targets in OG5_128412
Candida albicans Ubiquitin activating enzyme Get druggable targets OG5_128095 All targets in OG5_128095
Schistosoma mansoni app binding protein Get druggable targets OG5_128412 All targets in OG5_128412
Entamoeba histolytica ubiquitin-activating enzyme, putative Get druggable targets OG5_127070 All targets in OG5_127070
Trichomonas vaginalis ubiquitin-activating enzyme E1c, putative Get druggable targets OG5_127070 All targets in OG5_127070
Loa Loa (eye worm) ube1-prov protein Get druggable targets OG5_127070 All targets in OG5_127070
Trypanosoma brucei gambiense ubiquitin-activating enzyme e1, putative Get druggable targets OG5_128095 All targets in OG5_128095
Plasmodium berghei ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Leishmania mexicana ubiquitin activating enzyme, putative Get druggable targets OG5_128095 All targets in OG5_128095
Candida albicans Required for activation of RUB1 Get druggable targets OG5_128412 All targets in OG5_128412
Plasmodium vivax ubiquitin activating enzyme, putative Get druggable targets OG5_128859 All targets in OG5_128859
Plasmodium falciparum NEDD8-activating enzyme E1 catalytic subunit, putative Get druggable targets OG5_128095 All targets in OG5_128095
Loa Loa (eye worm) ectopic membrane ruffles in embryo protein 1 Get druggable targets OG5_128095 All targets in OG5_128095
Cryptosporidium parvum ubiquitin-activating enzyme E1 (UBA) Get druggable targets OG5_127070 All targets in OG5_127070
Theileria parva hypothetical protein, conserved Get druggable targets OG5_128095 All targets in OG5_128095
Plasmodium knowlesi SUMO-activating enzyme subunit 1, putative Get druggable targets OG5_128859 All targets in OG5_128859
Theileria parva hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Toxoplasma gondii NEDD8-activating enzyme E1 catalytic subunit Get druggable targets OG5_128095 All targets in OG5_128095
Trypanosoma cruzi ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Schistosoma mansoni ubiquitin-activating enzyme E1 Get druggable targets OG5_127070 All targets in OG5_127070
Schistosoma japonicum ko:K06917 tRNA 2-selenouridine synthase, putative Get druggable targets OG5_128095 All targets in OG5_128095
Toxoplasma gondii ThiF family protein Get druggable targets OG5_128412 All targets in OG5_128412
Entamoeba histolytica ThiF family protein Get druggable targets OG5_128412 All targets in OG5_128412
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative Get druggable targets OG5_128412 All targets in OG5_128412
Schistosoma japonicum ko:K04532 amyloid beta precursor protein binding protein 1, putative Get druggable targets OG5_128412 All targets in OG5_128412
Leishmania mexicana hypothetical protein, conserved Get druggable targets OG5_128412 All targets in OG5_128412
Plasmodium knowlesi NEDD8-activating enzyme E1 catalytic subunit, putative Get druggable targets OG5_128095 All targets in OG5_128095
Schistosoma mansoni sumo-1-activating enzyme E1a Get druggable targets OG5_128859 All targets in OG5_128859
Plasmodium yoelii SUMO-1 activating enzyme subunit 1 Get druggable targets OG5_128859 All targets in OG5_128859
Neospora caninum ubiquitin-activating enzyme, putative Get druggable targets OG5_128095 All targets in OG5_128095
Plasmodium vivax ubiquitin-activating enzyme E1C, putative Get druggable targets OG5_128095 All targets in OG5_128095
Leishmania infantum ubiquitin-activating enzyme e1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Neospora caninum Ubiquitin-activating enzyme E1, related Get druggable targets OG5_127070 All targets in OG5_127070
Schistosoma japonicum NEDD8-activating enzyme E1 catalytic subunit, putative Get druggable targets OG5_128095 All targets in OG5_128095
Entamoeba histolytica ubiquitin-activating enzyme, putative Get druggable targets OG5_128095 All targets in OG5_128095
Candida albicans similar to S. pombe uba5 (SPAC323.06c) ubiquitin activating enzyme and to S. cerevisiae ULA1 (YPL003W) Get druggable targets OG5_128412 All targets in OG5_128412
Echinococcus multilocularis ubiquitin modifier activating enzyme 1 Get druggable targets OG5_127070 All targets in OG5_127070
Brugia malayi ThiF family protein Get druggable targets OG5_128859 All targets in OG5_128859
Trypanosoma congolense ubiquitin activating enzyme, putative Get druggable targets OG5_128412 All targets in OG5_128412
Cryptosporidium parvum Uba3p like ubiquitin activating enzyme E1 Get druggable targets OG5_128095 All targets in OG5_128095
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Neospora caninum hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Trypanosoma brucei gambiense ubiquitin activating enzyme, putative Get druggable targets OG5_128412 All targets in OG5_128412
Schistosoma japonicum NEDD8-activating enzyme E1 catalytic subunit, putative Get druggable targets OG5_128095 All targets in OG5_128095
Echinococcus granulosus NEDD8 activating enzyme E1 regulatory subunit Get druggable targets OG5_128412 All targets in OG5_128412
Candida albicans similar to S. cerevisiae AOS1 (YPR180W) which mediates conjugation of ubiquitin-like Smt3p (sumoylation) to target proteins Get druggable targets OG5_128859 All targets in OG5_128859
Schistosoma mansoni sumo-1-activating enzyme E1a Get druggable targets OG5_128859 All targets in OG5_128859
Trypanosoma cruzi NEDD8-activating enzyme E1 regulatory subunit, putative Get druggable targets OG5_128412 All targets in OG5_128412
Trypanosoma congolense ubiquitin activating enzyme, putative Get druggable targets OG5_128412 All targets in OG5_128412
Trypanosoma cruzi ubiquitin activating enzyme, putative Get druggable targets OG5_128095 All targets in OG5_128095
Echinococcus granulosus ubiquitin modifier activating enzyme 1 Get druggable targets OG5_127070 All targets in OG5_127070
Leishmania donovani ubiquitin activating enzyme, putative Get druggable targets OG5_128095 All targets in OG5_128095
Babesia bovis ThiF family domain containing protein Get druggable targets OG5_128095 All targets in OG5_128095
Brugia malayi ThiF family protein Get druggable targets OG5_128412 All targets in OG5_128412
Leishmania braziliensis ubiquitin activating enzyme, putative Get druggable targets OG5_128095 All targets in OG5_128095
Leishmania major hypothetical protein, conserved Get druggable targets OG5_128412 All targets in OG5_128412
Toxoplasma gondii hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Brugia malayi ube1-prov protein Get druggable targets OG5_127070 All targets in OG5_127070
Candida albicans Ubiquitin activating enzyme Get druggable targets OG5_128095 All targets in OG5_128095
Candida albicans similar to S. pombe uba5 (SPAC323.06c) ubiquitin activating enzyme and to S. cerevisiae ULA1 (YPL003W) Get druggable targets OG5_128412 All targets in OG5_128412
Echinococcus granulosus ubiquitin modifier activating enzyme 6 Get druggable targets OG5_127070 All targets in OG5_127070
Echinococcus multilocularis NEDD8 activating enzyme E1 regulatory subunit Get druggable targets OG5_128412 All targets in OG5_128412
Plasmodium falciparum ubiquitin-activating enzyme E1 Get druggable targets OG5_127070 All targets in OG5_127070
Leishmania mexicana ubiquitin-activating enzyme e1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Schistosoma japonicum ko:K03178 ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Schistosoma mansoni ubiquitin-activating enzyme E1C Get druggable targets OG5_128095 All targets in OG5_128095
Theileria parva hypothetical protein Get druggable targets OG5_128859 All targets in OG5_128859
Leishmania major ubiquitin-activating enzyme e1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative Get druggable targets OG5_128412 All targets in OG5_128412
Leishmania infantum hypothetical protein, conserved Get druggable targets OG5_128412 All targets in OG5_128412
Plasmodium yoelii Uba1 gene product-related Get druggable targets OG5_127070 All targets in OG5_127070
Schistosoma japonicum Ubiquitin-like modifier-activating enzyme 6, putative Get druggable targets OG5_127070 All targets in OG5_127070
Plasmodium berghei SUMO-activating enzyme subunit 1, putative Get druggable targets OG5_128859 All targets in OG5_128859
Leishmania infantum ubiquitin activating enzyme, putative Get druggable targets OG5_128095 All targets in OG5_128095
Plasmodium falciparum SUMO-activating enzyme subunit 1 Get druggable targets OG5_128859 All targets in OG5_128859
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128412 All targets in OG5_128412
Schistosoma japonicum ko:K10686 ubiquitin-activating enzyme E1 C, putative Get druggable targets OG5_128095 All targets in OG5_128095
Echinococcus granulosus NEDD8 activating enzyme E1 catalytic subunit Get druggable targets OG5_128095 All targets in OG5_128095
Trypanosoma cruzi ubiquitin activating enzyme, putative Get druggable targets OG5_128095 All targets in OG5_128095
Trichomonas vaginalis molybdopterin biosynthesis moeb protein, putative Get druggable targets OG5_128095 All targets in OG5_128095
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Plasmodium berghei NEDD8-activating enzyme E1 catalytic subunit, putative Get druggable targets OG5_128095 All targets in OG5_128095
Cryptosporidium hominis ubiquitin-activating enzyme Get druggable targets OG5_128095 All targets in OG5_128095
Brugia malayi Ectopic membrane ruffles in embryo protein 1 Get druggable targets OG5_128095 All targets in OG5_128095
Entamoeba histolytica ubiquitin-activating enzyme E1 1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Leishmania donovani ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Schistosoma japonicum ko:K10684 ubiquitin-like 1-activating enzyme E1 A, putative Get druggable targets OG5_128859 All targets in OG5_128859
Trypanosoma congolense ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Echinococcus granulosus SUMO activating enzyme subunit 1 Get druggable targets OG5_128859 All targets in OG5_128859
Theileria parva ubiquitin-protein ligase, putative Get druggable targets OG5_127070 All targets in OG5_127070
Echinococcus multilocularis SUMO activating enzyme subunit 1 Get druggable targets OG5_128859 All targets in OG5_128859
Leishmania donovani hypothetical protein, conserved Get druggable targets OG5_128412 All targets in OG5_128412
Trypanosoma congolense ubiquitin-activating enzyme E1, putative Get druggable targets OG5_128095 All targets in OG5_128095
Candida albicans similar to S. cerevisiae AOS1 (YPR180W) which mediates conjugation of ubiquitin-like Smt3p (sumoylation) to target proteins Get druggable targets OG5_128859 All targets in OG5_128859
Trypanosoma cruzi ubiquitin-activating enzyme E1, putative Get druggable targets OG5_127070 All targets in OG5_127070
Neospora caninum GF23890, related Get druggable targets OG5_128412 All targets in OG5_128412
Leishmania major ubiquitin activating enzyme, putative Get druggable targets OG5_128095 All targets in OG5_128095
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei ubiquitin-activating enzyme E1, putative ubiquitin-like modifier activating enzyme 6 1052 aa 1017 aa 30.0 %
Trypanosoma brucei ubiquitin-activating enzyme E1, putative ubiquitin-like modifier activating enzyme 7 1012 aa 1020 aa 31.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major ubiquitin-activating enzyme e1, putative 0.0061 0.2131 0.5203
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0065 0.2421 0.0967
Plasmodium falciparum ubiquitin-activating enzyme E1 0.0163 1 1
Echinococcus granulosus NEDD8 activating enzyme E1 catalytic subunit 0.0087 0.4141 0.3017
Brugia malayi Ectopic membrane ruffles in embryo protein 1 0.0087 0.4141 0.3017
Schistosoma mansoni clathrin coat associated protein ap-50 0.01 0.5175 0.6093
Entamoeba histolytica ubiquitin-activating enzyme, putative 0.0087 0.4141 0.3017
Trypanosoma cruzi ubiquitin-activating enzyme E1, putative 0.0086 0.4095 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.2421 0.0967
Giardia lamblia Ubiquitin-conjugating enzyme E1 0.0086 0.4095 0.5
Leishmania major hypothetical protein, conserved 0.0054 0.1609 0.3929
Loa Loa (eye worm) ube1-prov protein 0.0163 1 1
Echinococcus multilocularis ubiquitin modifier activating enzyme 1 0.0163 1 1
Schistosoma mansoni ubiquitin-activating enzyme E1C 0.0087 0.4141 0.4378
Trichomonas vaginalis ubiquitin-activating enzyme E1 X, putative 0.0056 0.1739 0.2436
Echinococcus granulosus ubiquitin modifier activating enzyme 6 0.0163 1 1
Echinococcus multilocularis ubiquitin modifier activating enzyme 6 0.0163 1 1
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0051 0.1372 0.1922
Schistosoma mansoni ubiquitin-activating enzyme E1 0.0131 0.7531 1
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0061 0.2131 0.5203
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0126 0.714 1
Trypanosoma cruzi ubiquitin-activating enzyme E1, putative 0.0086 0.4095 1
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0065 0.2421 0.0967
Schistosoma mansoni clathrin coat associated protein ap-50 0.01 0.5175 0.6093
Brugia malayi ThiF family protein 0.0065 0.2421 0.0967
Trypanosoma brucei NEDD8-activating enzyme E1 regulatory subunit, putative 0.0054 0.1609 0.3929
Trichomonas vaginalis ubiquitin-activating enzyme E1c, putative 0.0126 0.714 1
Schistosoma mansoni app binding protein 0.0054 0.1609 0.018
Toxoplasma gondii NEDD8-activating enzyme E1 catalytic subunit 0.0087 0.4141 1
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0086 0.4095 1
Loa Loa (eye worm) ectopic membrane ruffles in embryo protein 1 0.0087 0.4141 0.3017
Echinococcus granulosus ubiquitin modifier activating enzyme 1 0.0163 1 1
Plasmodium vivax ubiquitin activating enzyme, putative 0.0065 0.2421 1
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0065 0.2421 0.1526
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0054 0.1609 0.2254
Leishmania major ubiquitin-activating enzyme e1, putative 0.0086 0.4095 1
Toxoplasma gondii hypothetical protein 0.0065 0.2421 0.3205
Trypanosoma cruzi NEDD8-activating enzyme E1 regulatory subunit, putative 0.0054 0.1609 0.3929
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0054 0.1609 0.2254
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0065 0.2421 0.2421
Entamoeba histolytica ubiquitin-activating enzyme E1 1, putative 0.0126 0.714 0.6591
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0065 0.2469 0.3458
Trichomonas vaginalis ubiquitin-activating enzyme E1, putative 0.0126 0.714 1
Trypanosoma cruzi ubiquitin-activating enzyme E1, putative 0.0049 0.1188 0.2902
Entamoeba histolytica ubiquitin-activating enzyme, putative 0.0163 1 1
Echinococcus multilocularis NEDD8 activating enzyme E1 catalytic subunit 0.0087 0.4141 0.3017

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 125 nM Antiproliferative activity against human K562 cells after 72 hrs by CellTiter-Glo assay ChEMBL. 24900352
IC50 (binding) = 0.01 uM Inhibition of NAE (unknown origin) in presence of ATP ChEMBL. 23360215
IC50 (binding) <= 0.1 uM Inhibition of recombinant human untagged NAEalpha/N-terminal His-tagged NAEbeta expressed in Bac-to-Bac expression system using FLAG-tagged NEDD8 as substrate after 90 mins in presence of GST-tagged Ubc12 by HTRF assay PATENT. No reference
IC50 (binding) = 0.92 uM Inhibition of UBA6 (unknown origin) in presence of ATP ChEMBL. 23360215
IC50 (binding) = 4 uM Inhibition of UBA7 (unknown origin) in presence of ATP ChEMBL. 23360215
IC50 (binding) = 6.4 uM Inhibition of SAE (unknown origin) in presence of ATP ChEMBL. 23360215
IC50 (binding) = 100 uM Inhibition of ATG7 (unknown origin) in presence of ATP ChEMBL. 23360215
Inhibition (binding) Inhibition of human recombinant SAE1/2 assessed as inhibition of SUMO1-UbcH9 complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis ChEMBL. 24900352
Inhibition (binding) Inhibition of UBA3-mediated NEDD8 activation at 10 mM after 1.5 hrs by Western blot analysis ChEMBL. 24900352
Inhibition (binding) Inhibition of APPBP1-mediated NEDD8 activation at 10 mM after 1.5 hrs by Western blot analysis ChEMBL. 24900352
Inhibition (binding) Inhibition of human recombinant UBA5 assessed as inhibition of UCF1-UFM1 complex formation at 10 uM after 1.5 hrs by Western blot analysis ChEMBL. 24900352

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 24900352

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.