Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0816 | 0.3913 | 0.4806 |
Loa Loa (eye worm) | hypothetical protein | 0.2024 | 0.9806 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0833 | 0.3998 | 1 |
Mycobacterium tuberculosis | Probable serine acetyltransferase CysE (sat) | 0.0071 | 0.0277 | 0.0211 |
Echinococcus multilocularis | carbonic anhydrase | 0.0833 | 0.3998 | 0.4911 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0019 | 0.002 |
Echinococcus multilocularis | carbonic anhydrase | 0.0833 | 0.3998 | 0.4911 |
Entamoeba histolytica | acetyltransferase, putative | 0.0071 | 0.0277 | 0.029 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0171 | 0.0766 | 0.0939 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0019 | 0.0007 |
Leishmania major | DNA topoisomerase ii | 0.0063 | 0.0241 | 0.0214 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.016 | 0.0711 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0018 | 0.0019 | 0.0019 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.0071 | 0.0277 | 0.1184 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0595 | 0.2836 | 0.3884 |
Loa Loa (eye worm) | hypothetical protein | 0.0833 | 0.3998 | 0.4077 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.168 | 0.8128 | 0.8289 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0019 | 0.0007 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0019 | 0.0023 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.1507 | 0.7283 | 1 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0049 | 0.0171 | 0.021 |
Echinococcus granulosus | carbonic anhydrase II | 0.168 | 0.8128 | 1 |
Echinococcus multilocularis | DNA topoisomerase 3 beta 1 | 0.0028 | 0.0068 | 0.0068 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0109 | 0.0056 |
Onchocerca volvulus | 0.0027 | 0.0064 | 0.0659 | |
Brugia malayi | hypothetical protein | 0.0036 | 0.0109 | 0.013 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0019 | 0.002 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0164 | 0.0733 | 0.0899 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.168 | 0.8128 | 0.8289 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.168 | 0.8128 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.2064 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0019 | 0.0019 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0019 | 0.0007 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0036 | 0.0109 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0109 | 0.0056 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0019 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0019 | 0.0023 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0068 | 0.0264 | 0.0197 |
Echinococcus granulosus | carbonic anhydrase | 0.0833 | 0.3998 | 0.4919 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0019 | 0.0023 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0019 | 0.0023 |
Plasmodium falciparum | DNA gyrase subunit B | 0.039 | 0.1834 | 0.4495 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0019 | 0.002 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0019 | 0.0007 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.1507 | 0.7283 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0019 | 0.002 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0833 | 0.3998 | 0.4917 |
Echinococcus multilocularis | carbonic anhydrase II | 0.168 | 0.8128 | 1 |
Echinococcus granulosus | DNA topoisomerase 3 alpha | 0.0028 | 0.0068 | 0.0084 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0019 | 0.0023 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.039 | 0.1834 | 0.2447 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0091 | 0.0377 | 0.0428 |
Echinococcus granulosus | DNA topoisomerase 3 beta 1 | 0.0028 | 0.0068 | 0.0084 |
Mycobacterium ulcerans | transferase | 0.0068 | 0.0264 | 0.0197 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0019 | 0.002 |
Schistosoma mansoni | carbonic anhydrase | 0.1507 | 0.7283 | 0.896 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.1468 | 0.7096 | 1 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.0911 | 0.4379 | 0.6099 |
Plasmodium falciparum | carbonic anhydrase | 0.0833 | 0.3998 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0064 | 0.0079 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0019 | 0.0023 |
Echinococcus granulosus | carbonic anhydrase | 0.0833 | 0.3998 | 0.4919 |
Mycobacterium leprae | Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) | 0.0134 | 0.0587 | 0.0719 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0019 | 0.002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.2064 | 1 | 1 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0225 | 0.1032 | 0.1196 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.039 | 0.1834 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0019 | 0.002 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1507 | 0.7283 | 0.7264 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0064 | 0.0066 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0833 | 0.3998 | 0.4919 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0091 | 0.0377 | 0.0384 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.039 | 0.1834 | 1 |
Brugia malayi | hypoxia-induced factor 1 | 0.0152 | 0.0671 | 0.0822 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0225 | 0.1032 | 0.1196 |
Onchocerca volvulus | 0.0156 | 0.0693 | 0.9743 | |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0733 | 0.0748 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0019 | 0.0023 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0152 | 0.0671 | 0.0684 |
Mycobacterium ulcerans | putative regulatory protein | 0.0036 | 0.0109 | 0.0041 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0019 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0062 | 0.0063 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0064 | 0.0079 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.168 | 0.8128 | 1 |
Schistosoma mansoni | prokaryotic DNA topoisomerase | 0.0028 | 0.0068 | 0.0084 |
Loa Loa (eye worm) | DNA topoisomerase III | 0.0028 | 0.0068 | 0.0069 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0833 | 0.3998 | 0.4919 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0109 | 0.0134 |
Brugia malayi | PAS domain containing protein | 0.0049 | 0.0171 | 0.0207 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0019 | 0.0023 |
Echinococcus multilocularis | rho GTPase activating protein 20 | 0.0028 | 0.0068 | 0.0068 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0109 | 0.0118 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0019 | 0.0007 |
Schistosoma mansoni | DNA topoisomerase II | 0.0091 | 0.0377 | 0.0463 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0091 | 0.0377 | 0.046 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0013 | 0.0013 |
Brugia malayi | Probable DNA topoisomerase II | 0.0091 | 0.0377 | 0.046 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0018 | 0.0019 | 0.0019 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0019 | 0.0023 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0063 | 0.0241 | 0.0214 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0833 | 0.3998 | 0.4917 |
Giardia lamblia | DNA topoisomerase II | 0.0079 | 0.0317 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0019 | 0.002 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0833 | 0.3998 | 0.4077 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0109 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0013 | 0.0013 |
Onchocerca volvulus | 0.0036 | 0.0109 | 0.13 | |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0091 | 0.0377 | 0.517 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.013 | 0.0077 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0064 | 0.0063 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0019 | 0.002 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0019 | 0.0023 |
Schistosoma mansoni | prokaryotic DNA topoisomerase | 0.0028 | 0.0068 | 0.0084 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0028 | 0.0068 | 0.008 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0091 | 0.0377 | 0.0311 |
Schistosoma mansoni | hypothetical protein | 0.0833 | 0.3998 | 0.4919 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0019 | 0.002 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0019 | 0.002 |
Trichomonas vaginalis | maltose O-acetyltransferase, putative | 0.0068 | 0.0264 | 0.0197 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0019 | 0.002 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0833 | 0.3998 | 0.4917 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.013 | 0.0077 |
Echinococcus granulosus | single minded 2 | 0.0036 | 0.0109 | 0.0134 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.039 | 0.1834 | 1 |
Brugia malayi | DNA topoisomerase III beta-1 | 0.0028 | 0.0068 | 0.008 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.168 | 0.8128 | 1 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0091 | 0.0377 | 0.0463 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0019 | 0.002 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0225 | 0.1032 | 0.1196 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0064 | 0.0066 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0019 | 0.0019 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0225 | 0.1032 | 0.1196 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0091 | 0.0377 | 0.0785 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0019 | 0.0023 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.039 | 0.1834 | 1 |
Brugia malayi | GRF zinc finger family protein | 0.0028 | 0.0068 | 0.008 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.013 | 0.0077 |
Onchocerca volvulus | 0.0027 | 0.0064 | 0.0659 | |
Schistosoma mansoni | carbonic anhydrase | 0.0833 | 0.3998 | 0.4919 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0091 | 0.0377 | 0.046 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0019 | 0.0019 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0019 | 0.002 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.039 | 0.1834 | 0.1779 |
Schistosoma mansoni | lamin | 0.0027 | 0.0064 | 0.0079 |
Echinococcus granulosus | roundabout 2 | 0.0017 | 0.0013 | 0.0016 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0019 | 0.0019 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0063 | 0.0241 | 0.0214 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.168 | 0.8128 | 1 |
Leishmania major | carbonic anhydrase family protein, putative | 0.1507 | 0.7283 | 0.8951 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0019 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0241 | 0.0245 |
Mycobacterium leprae | PROBABLE TRANSFERASE | 0.0068 | 0.0264 | 0.0272 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0019 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0064 | 0.0066 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0091 | 0.0377 | 0.0448 |
Schistosoma mansoni | single-minded | 0.0049 | 0.0171 | 0.021 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0064 | 0.0076 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0833 | 0.3998 | 0.4917 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0091 | 0.0377 | 0.517 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0064 | 0.0076 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0091 | 0.0377 | 0.517 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0833 | 0.3998 | 0.4919 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0019 | 0.002 |
Echinococcus granulosus | dynactin 5 p25 | 0.0071 | 0.0277 | 0.0341 |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0019 | 0.0023 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0256 | 0.1179 | 0.6322 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0109 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0833 | 0.3998 | 0.4077 |
Wolbachia endosymbiont of Brugia malayi | carbonic anhydrase | 0.0041 | 0.013 | 0.0351 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0064 | 0.0063 |
Schistosoma mansoni | lamin | 0.0027 | 0.0064 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0109 | 0.0134 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0064 | 0.0079 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.168 | 0.8128 | 1 |
Brugia malayi | DNA topoisomerase III | 0.0028 | 0.0068 | 0.008 |
Entamoeba histolytica | bacterial transferase hexapeptide family protein | 0.0041 | 0.013 | 0.0086 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0019 | 0.002 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | bHLH-PAS transcription factor | 0.0036 | 0.0109 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0241 | 0.0245 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0833 | 0.3998 | 0.4917 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0019 | 0.002 |
Leishmania major | carbonic anhydrase-like protein | 0.168 | 0.8128 | 1 |
Loa Loa (eye worm) | DNA topoisomerase III beta-1 | 0.0028 | 0.0068 | 0.0069 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0019 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Wolbachia endosymbiont of Brugia malayi | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase | 0.0071 | 0.0277 | 0.1184 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0109 | 0.0134 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0171 | 0.0766 | 0.0781 |
Entamoeba histolytica | ankyrin, putative | 0.0071 | 0.0277 | 0.029 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.168 | 0.8128 | 1 |
Onchocerca volvulus | 0.0068 | 0.0264 | 0.3545 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0019 | 0.002 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0091 | 0.0377 | 0.1747 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0019 | 0.0023 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0063 | 0.0241 | 0.0214 |
Onchocerca volvulus | 0.0028 | 0.0068 | 0.0711 | |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0063 | 0.0241 | 0.0214 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.168 | 0.8128 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0833 | 0.3998 | 0.4919 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.013 | 0.0062 |
Echinococcus multilocularis | carbonic anhydrase | 0.0833 | 0.3998 | 0.4911 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0225 | 0.1032 | 0.2452 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0019 | 0.0007 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0019 | 0.002 |
Echinococcus granulosus | lamin | 0.0027 | 0.0064 | 0.0079 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0091 | 0.0377 | 0.0785 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0019 | 0.0007 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0019 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0019 | 0.0019 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.013 | 0.0077 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0064 | 0.0063 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Drug uptake (ADMET) | = 8.13 % ID/g | Biodistribution in ICR mouse kidney at 925 KBq, iv after 2 mins by gamma counting | ChEMBL. | 22011144 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.