Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | glycogen synthase kinase 3 beta | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | reprolysin | 0.0103 | 0.0417 | 0.0417 |
Brugia malayi | angiogenesis inhibito | 0.0183 | 0.2284 | 0.2284 |
Echinococcus granulosus | a disintegrin and metalloproteinase with | 0.0288 | 0.4721 | 1 |
Echinococcus granulosus | adam 17 protease | 0.0198 | 0.2627 | 0.5135 |
Loa Loa (eye worm) | angiogenesis inhibito | 0.0097 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1611 | 0.1611 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.6815 | 0.6815 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.1992 | 0.1992 |
Echinococcus multilocularis | adam | 0.0188 | 0.2409 | 0.463 |
Echinococcus multilocularis | Blood coagulation inhibitor, Disintegrin | 0.0113 | 0.0652 | 0.0547 |
Schistosoma mansoni | subfamily M12B unassigned peptidase (M12 family) | 0.0103 | 0.0417 | 0.0883 |
Loa Loa (eye worm) | hypothetical protein | 0.0515 | 1 | 1 |
Brugia malayi | metalloprotease disintegrin 16 with thrombospondin type I motif | 0.0085 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0021 | 0.0021 |
Brugia malayi | ADAMTS-like protease | 0.0183 | 0.2284 | 0.2284 |
Onchocerca volvulus | Papilin homolog | 0.0154 | 0.1611 | 0.5 |
Schistosoma mansoni | ADAMTS5 peptidase (M12 family) | 0.0288 | 0.4721 | 1 |
Echinococcus multilocularis | adam 17 protease | 0.018 | 0.221 | 0.4166 |
Echinococcus multilocularis | a disintegrin and metalloproteinase with | 0.0288 | 0.4721 | 1 |
Schistosoma mansoni | ADAM17 peptidase (M12 family) | 0.018 | 0.221 | 0.4682 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0417 | 0.0417 |
Brugia malayi | hypothetical protein | 0.0188 | 0.2409 | 0.2409 |
Echinococcus granulosus | Blood coagulation inhibitor Disintegrin | 0.0113 | 0.0652 | 0.0547 |
Schistosoma mansoni | adam (A disintegrin and metalloprotease | 0.0188 | 0.2409 | 0.5104 |
Schistosoma mansoni | subfamily M12B unassigned peptidase (M12 family) | 0.0103 | 0.0417 | 0.0883 |
Echinococcus granulosus | adam | 0.0188 | 0.2409 | 0.463 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.