Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | YY1-associated factor 2 | 0.012 | 0.0666 | 0.1834 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.012 | 0.0666 | 1 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.012 | 0.0666 | 0.1834 |
Entamoeba histolytica | protein kinase, putative | 0.0075 | 0.0055 | 0.0578 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0666 | 0.1817 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0336 | 0.3634 | 1 |
Chlamydia trachomatis | SWIB complex protein | 0.0336 | 0.3634 | 0.5 |
Loa Loa (eye worm) | brahma associated protein | 0.0336 | 0.3634 | 0.9905 |
Schistosoma mansoni | brg-1 associated factor | 0.0336 | 0.3634 | 1 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0336 | 0.3634 | 1 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.012 | 0.0666 | 0.0666 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.012 | 0.0666 | 0.0108 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Toxoplasma gondii | ran binding protein | 0.012 | 0.0666 | 0.1834 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0123 | 0.0711 | 0.1937 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0336 | 0.3634 | 0.3634 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.3634 | 1 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.012 | 0.0666 | 0.5 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.0666 | 0.1834 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.06 | 0.1636 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0256 | 0.2539 | 0.6988 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0336 | 0.3634 | 0.3634 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0077 | 0.0083 | 0.0229 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.012 | 0.0666 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.3634 | 1 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0275 | 0.2801 | 0.2801 |
Onchocerca volvulus | 0.012 | 0.0666 | 0.0108 | |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.0666 | 0.1834 |
Brugia malayi | brahma associated protein 60 kDa | 0.0336 | 0.3634 | 1 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0256 | 0.2539 | 0.2539 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0115 | 0.06 | 0.06 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0184 | 0.1557 | 0.4244 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.153 | 0.417 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0256 | 0.2539 | 0.2539 |
Brugia malayi | C1-like domain containing protein | 0.0184 | 0.1557 | 0.4285 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0336 | 0.3634 | 0.5 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.012 | 0.0666 | 0.0666 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0075 | 0.0055 | 0.0149 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0336 | 0.3634 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0634 | 0.1728 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.3634 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0336 | 0.3634 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.358 | 0.976 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0336 | 0.3634 | 1 |
Brugia malayi | protein kinase C II. | 0.0275 | 0.2801 | 0.7709 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.014 | 0.0944 | 1 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Onchocerca volvulus | 0.0118 | 0.0646 | 0.0041 | |
Onchocerca volvulus | 0.0336 | 0.3634 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.1484 | 0.4045 |
Onchocerca volvulus | 0.012 | 0.0666 | 0.0108 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0275 | 0.2801 | 0.7709 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.012 | 0.0666 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0666 | 0.1817 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.012 | 0.0666 | 0.5 |
Brugia malayi | Protein kinase c protein 2 | 0.0187 | 0.1594 | 0.4388 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0666 | 0.1817 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0256 | 0.2539 | 0.6988 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0336 | 0.3634 | 0.3634 |
Schistosoma mansoni | atypical protein kinase C | 0.0221 | 0.206 | 0.5669 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.012 | 0.0666 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Brugia malayi | brahma associated protein 60 kDa | 0.0336 | 0.3634 | 1 |
Onchocerca volvulus | 0.0186 | 0.1584 | 0.3168 | |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.2697 | 0.7351 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0117 | 0.0634 | 0.1745 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0336 | 0.3634 | 0.5 |
Onchocerca volvulus | 0.0182 | 0.153 | 0.2987 | |
Echinococcus granulosus | protein kinase c epsilon type | 0.0275 | 0.2801 | 0.2801 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0646 | 0.1762 |
Echinococcus granulosus | ring and YY1 binding protein | 0.012 | 0.0666 | 0.0666 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.0666 | 0.1834 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.012 | 0.0666 | 0.0666 |
Schistosoma mansoni | protein kinase C mu | 0.0184 | 0.1557 | 0.4285 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0192 | 0.1656 | 0.1656 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0336 | 0.3634 | 0.3634 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.012 | 0.0666 | 0.5 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0336 | 0.3634 | 0.9905 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Echinococcus multilocularis | tumor protein p63 | 0.08 | 1 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.012 | 0.0666 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0666 | 0.1817 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.2697 | 0.7351 |
Entamoeba histolytica | protein kinase, putative | 0.0075 | 0.0055 | 0.0578 |
Echinococcus granulosus | protein kinase C gamma type | 0.0192 | 0.1656 | 0.1656 |
Schistosoma mansoni | RNA binding protein | 0.012 | 0.0666 | 0.1834 |
Schistosoma mansoni | fusion | 0.012 | 0.0666 | 0.1834 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.012 | 0.0666 | 0.1834 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0666 | 0.1817 |
Onchocerca volvulus | 0.012 | 0.0666 | 0.0108 | |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.012 | 0.0673 | 0.1835 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0646 | 0.1762 |
Trypanosoma brucei | hypothetical protein, conserved | 0.012 | 0.0666 | 1 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.012 | 0.0666 | 0.0666 |
Schistosoma mansoni | hypothetical protein | 0.012 | 0.0666 | 0.1834 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0205 | 0.1834 | 0.1834 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0136 | 0.0889 | 0.0889 |
Schistosoma mansoni | zinc finger protein | 0.012 | 0.0666 | 0.1834 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.012 | 0.0666 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.3669 | 1 |
Onchocerca volvulus | 0.012 | 0.0666 | 0.0108 | |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0336 | 0.3634 | 0.3634 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.012 | 0.0666 | 0.5 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.012 | 0.0666 | 0.0666 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.012 | 0.0666 | 0.0666 |
Echinococcus multilocularis | protein kinase c iota type | 0.0215 | 0.1979 | 0.1979 |
Echinococcus granulosus | protein kinase c iota type | 0.0215 | 0.1979 | 0.1979 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.2697 | 0.7351 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0184 | 0.1557 | 0.4285 |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.0152 | 0.1115 | 0.3039 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.0666 | 0.1834 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0336 | 0.3634 | 0.3634 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0115 | 0.06 | 0.06 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0336 | 0.3634 | 1 |
Brugia malayi | protein kinase C3,putative | 0.0146 | 0.1034 | 0.2847 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0115 | 0.06 | 0.06 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.012 | 0.0666 | 0.0666 |
Brugia malayi | Protein kinase domain containing protein | 0.0075 | 0.0055 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1584 | 0.4319 |
Onchocerca volvulus | 0.0268 | 0.2697 | 0.6876 | |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0275 | 0.2801 | 0.7636 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0336 | 0.3634 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.