Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0068 | 0.0264 | 0.0197 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0019 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0019 | 0.002 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0019 | 0.0007 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0019 | 0.0023 |
Plasmodium falciparum | DNA gyrase subunit B | 0.039 | 0.1834 | 0.4495 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0019 | 0.0023 |
Echinococcus granulosus | carbonic anhydrase | 0.0833 | 0.3998 | 0.4919 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0109 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0036 | 0.0109 | 0.0118 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0019 | 0.0007 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0019 | 0.0023 |
Echinococcus granulosus | DNA topoisomerase 3 beta 1 | 0.0028 | 0.0068 | 0.0084 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0091 | 0.0377 | 0.0428 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.039 | 0.1834 | 0.2447 |
Schistosoma mansoni | carbonic anhydrase | 0.1507 | 0.7283 | 0.896 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0019 | 0.002 |
Mycobacterium ulcerans | transferase | 0.0068 | 0.0264 | 0.0197 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.1507 | 0.7283 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0019 | 0.002 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0019 | 0.0023 |
Echinococcus granulosus | DNA topoisomerase 3 alpha | 0.0028 | 0.0068 | 0.0084 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0833 | 0.3998 | 0.4917 |
Echinococcus multilocularis | carbonic anhydrase II | 0.168 | 0.8128 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0018 | 0.0019 | 0.0019 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.016 | 0.0711 | 1 |
Leishmania major | DNA topoisomerase ii | 0.0063 | 0.0241 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0833 | 0.3998 | 0.4077 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0595 | 0.2836 | 0.3884 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.168 | 0.8128 | 0.8289 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.0071 | 0.0277 | 0.1184 |
Echinococcus multilocularis | carbonic anhydrase | 0.0833 | 0.3998 | 0.4911 |
Mycobacterium tuberculosis | Probable serine acetyltransferase CysE (sat) | 0.0071 | 0.0277 | 0.0211 |
Toxoplasma gondii | hypothetical protein | 0.0833 | 0.3998 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2024 | 0.9806 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0816 | 0.3913 | 0.4806 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0019 | 0.0007 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0171 | 0.0766 | 0.0939 |
Entamoeba histolytica | acetyltransferase, putative | 0.0071 | 0.0277 | 0.029 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0019 | 0.002 |
Echinococcus multilocularis | carbonic anhydrase | 0.0833 | 0.3998 | 0.4911 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0109 | 0.013 |
Onchocerca volvulus | 0.0027 | 0.0064 | 0.0659 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.2064 | 1 | 1 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.168 | 0.8128 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0164 | 0.0733 | 0.0899 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.168 | 0.8128 | 0.8289 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0019 | 0.002 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0019 | 0.0007 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0019 | 0.0023 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.1507 | 0.7283 | 1 |
Echinococcus multilocularis | DNA topoisomerase 3 beta 1 | 0.0028 | 0.0068 | 0.0068 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0109 | 0.0056 |
Echinococcus granulosus | carbonic anhydrase II | 0.168 | 0.8128 | 1 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0049 | 0.0171 | 0.021 |
Echinococcus multilocularis | rho GTPase activating protein 20 | 0.0028 | 0.0068 | 0.0068 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0019 | 0.0023 |
Schistosoma mansoni | DNA topoisomerase II | 0.0091 | 0.0377 | 0.0463 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0013 | 0.0013 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0091 | 0.0377 | 0.046 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0019 | 0.0007 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0109 | 0.0118 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0833 | 0.3998 | 0.4919 |
Brugia malayi | PAS domain containing protein | 0.0049 | 0.0171 | 0.0207 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0109 | 0.0134 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0109 | 0.0056 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0833 | 0.3998 | 0.4077 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0019 | 0.002 |
Giardia lamblia | DNA topoisomerase II | 0.0079 | 0.0317 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0013 | 0.0013 |
Onchocerca volvulus | 0.0036 | 0.0109 | 0.13 | |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0063 | 0.0241 | 0.0214 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0018 | 0.0019 | 0.0019 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | Probable DNA topoisomerase II | 0.0091 | 0.0377 | 0.046 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0833 | 0.3998 | 0.4917 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.039 | 0.1834 | 1 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0091 | 0.0377 | 0.0384 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0833 | 0.3998 | 0.4919 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0019 | 0.0019 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1507 | 0.7283 | 0.7264 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0064 | 0.0066 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0019 | 0.002 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.039 | 0.1834 | 1 |
Brugia malayi | hypoxia-induced factor 1 | 0.0152 | 0.0671 | 0.0822 |
Mycobacterium leprae | Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) | 0.0134 | 0.0587 | 0.0719 |
Echinococcus granulosus | carbonic anhydrase | 0.0833 | 0.3998 | 0.4919 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0019 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0064 | 0.0079 |
Plasmodium falciparum | carbonic anhydrase | 0.0833 | 0.3998 | 1 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.0911 | 0.4379 | 0.6099 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.1468 | 0.7096 | 1 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0225 | 0.1032 | 0.1196 |
Trichomonas vaginalis | conserved hypothetical protein | 0.2064 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0019 | 0.002 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0064 | 0.0079 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0019 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0062 | 0.0063 |
Loa Loa (eye worm) | DNA topoisomerase III | 0.0028 | 0.0068 | 0.0069 |
Schistosoma mansoni | prokaryotic DNA topoisomerase | 0.0028 | 0.0068 | 0.0084 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.168 | 0.8128 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0019 | 0.0023 |
Onchocerca volvulus | 0.0156 | 0.0693 | 0.9743 | |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0733 | 0.0748 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0225 | 0.1032 | 0.1196 |
Mycobacterium ulcerans | putative regulatory protein | 0.0036 | 0.0109 | 0.0041 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0152 | 0.0671 | 0.0684 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0003 | 0.0003 |
Echinococcus granulosus | roundabout 2 | 0.0017 | 0.0013 | 0.0016 |
Schistosoma mansoni | lamin | 0.0027 | 0.0064 | 0.0079 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.039 | 0.1834 | 0.1779 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0019 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0241 | 0.0245 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0019 | 0.0023 |
Leishmania major | carbonic anhydrase family protein, putative | 0.1507 | 0.7283 | 0.8951 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.168 | 0.8128 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0019 | 0.0019 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0063 | 0.0241 | 0.0214 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.039 | 0.1834 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0019 | 0.0023 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0091 | 0.0377 | 0.0785 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0225 | 0.1032 | 0.1196 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0019 | 0.0019 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0019 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0019 | 0.0019 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0091 | 0.0377 | 0.046 |
Onchocerca volvulus | 0.0027 | 0.0064 | 0.0659 | |
Schistosoma mansoni | carbonic anhydrase | 0.0833 | 0.3998 | 0.4919 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.013 | 0.0077 |
Brugia malayi | GRF zinc finger family protein | 0.0028 | 0.0068 | 0.008 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0064 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0091 | 0.0377 | 0.517 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0833 | 0.3998 | 0.4917 |
Schistosoma mansoni | single-minded | 0.0049 | 0.0171 | 0.021 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0091 | 0.0377 | 0.0448 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0064 | 0.0066 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0019 | 0.002 |
Mycobacterium leprae | PROBABLE TRANSFERASE | 0.0068 | 0.0264 | 0.0272 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0019 | 0.002 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0019 | 0.002 |
Schistosoma mansoni | hypothetical protein | 0.0833 | 0.3998 | 0.4919 |
Trichomonas vaginalis | maltose O-acetyltransferase, putative | 0.0068 | 0.0264 | 0.0197 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0019 | 0.0023 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0064 | 0.0063 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0019 | 0.002 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.013 | 0.0077 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0091 | 0.0377 | 0.517 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0091 | 0.0377 | 0.0311 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0028 | 0.0068 | 0.008 |
Schistosoma mansoni | prokaryotic DNA topoisomerase | 0.0028 | 0.0068 | 0.0084 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0019 | 0.002 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0091 | 0.0377 | 0.0463 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0064 | 0.0066 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0225 | 0.1032 | 0.1196 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.013 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0019 | 0.002 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0833 | 0.3998 | 0.4917 |
Brugia malayi | DNA topoisomerase III beta-1 | 0.0028 | 0.0068 | 0.008 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.168 | 0.8128 | 1 |
Echinococcus granulosus | single minded 2 | 0.0036 | 0.0109 | 0.0134 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.039 | 0.1834 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0833 | 0.3998 | 0.4919 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0063 | 0.0241 | 0.0214 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.168 | 0.8128 | 1 |
Onchocerca volvulus | 0.0028 | 0.0068 | 0.0711 | |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0063 | 0.0241 | 0.0214 |
Echinococcus multilocularis | carbonic anhydrase | 0.0833 | 0.3998 | 0.4911 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.013 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0171 | 0.0766 | 0.0781 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0091 | 0.0377 | 0.1747 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0019 | 0.002 |
Onchocerca volvulus | 0.0068 | 0.0264 | 0.3545 | |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.168 | 0.8128 | 1 |
Entamoeba histolytica | ankyrin, putative | 0.0071 | 0.0277 | 0.029 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0019 | 0.0007 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0064 | 0.0063 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.013 | 0.0077 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0019 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0019 | 0.0019 |
Echinococcus granulosus | lamin | 0.0027 | 0.0064 | 0.0079 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0019 | 0.002 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0019 | 0.0023 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0019 | 0.0007 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0225 | 0.1032 | 0.2452 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0091 | 0.0377 | 0.0785 |
Entamoeba histolytica | bacterial transferase hexapeptide family protein | 0.0041 | 0.013 | 0.0086 |
Brugia malayi | DNA topoisomerase III | 0.0028 | 0.0068 | 0.008 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.168 | 0.8128 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0064 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0109 | 0.0134 |
Brugia malayi | bHLH-PAS transcription factor | 0.0036 | 0.0109 | 0.013 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0019 | 0.0023 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0019 | 0.002 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0256 | 0.1179 | 0.6322 |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0019 | 0.0023 |
Echinococcus granulosus | dynactin 5 p25 | 0.0071 | 0.0277 | 0.0341 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0064 | 0.0076 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0833 | 0.3998 | 0.4919 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0019 | 0.002 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0091 | 0.0377 | 0.517 |
Schistosoma mansoni | lamin | 0.0027 | 0.0064 | 0.0079 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0064 | 0.0063 |
Wolbachia endosymbiont of Brugia malayi | carbonic anhydrase | 0.0041 | 0.013 | 0.0351 |
Loa Loa (eye worm) | hypothetical protein | 0.0833 | 0.3998 | 0.4077 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0109 | 0.0056 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0109 | 0.0134 |
Wolbachia endosymbiont of Brugia malayi | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase | 0.0071 | 0.0277 | 0.1184 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0019 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0241 | 0.0245 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0833 | 0.3998 | 0.4917 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0019 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0019 | 0.0007 |
Leishmania major | carbonic anhydrase-like protein | 0.168 | 0.8128 | 1 |
Loa Loa (eye worm) | DNA topoisomerase III beta-1 | 0.0028 | 0.0068 | 0.0069 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Drug uptake (ADMET) | = 3.12 % ID/g | Biodistribution in ICR mouse blood at 925 KBq, iv after 2 mins by gamma counting | ChEMBL. | 22011144 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.