Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | endothelin converting enzyme 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0484 | 0.0509 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0114 | 0.0934 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0484 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0484 | 0.0509 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0058 | 0.0019 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0934 | 0.0982 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0084 | 0.0452 | 0.0475 |
Onchocerca volvulus | 0.0056 | 0.0003 | 0.0003 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0407 | 0.5675 | 1 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0114 | 0.0934 | 0.0982 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0484 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0618 | 0.9088 | 0.9548 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0452 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0452 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0484 | 0.0509 |
Brugia malayi | Peptidase family M13 containing protein | 0.0114 | 0.0934 | 0.0982 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0114 | 0.0934 | 0.5 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0644 | 0.9518 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0407 | 0.5675 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0058 | 0.0019 | 0.0034 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0114 | 0.0934 | 0.1646 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0934 | 0.0982 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0058 | 0.0019 | 0.0034 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0084 | 0.0452 | 0.0475 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0114 | 0.0934 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0452 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0934 | 0.0982 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0058 | 0.0019 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0003 | 0.0003 |
Brugia malayi | nuclear hormone receptor | 0.0644 | 0.9518 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0377 | 0.5193 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0452 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0484 | 0.0509 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0114 | 0.0934 | 0.1799 |
Toxoplasma gondii | peptidase family M13 protein | 0.0114 | 0.0934 | 0.5 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0058 | 0.0019 | 0.0034 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0114 | 0.0934 | 0.1646 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.