Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | JmjC domain containing protein | 0.0045 | 0.0025 | 0.5 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0798 | 0.5951 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0147 | 0.0828 | 0.0828 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0042 | 0.0004 | 0.0004 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0061 | 0.0157 | 0.0157 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0147 | 0.0828 | 0.1392 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0042 | 0.0004 | 0.0004 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0142 | 0.0795 | 0.1336 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.021 | 0.1324 | 0.2556 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0231 | 0.1493 | 0.1493 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0231 | 0.1493 | 0.1493 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0042 | 0.0004 | 0.0007 |
Schistosoma mansoni | hypothetical protein | 0.0501 | 0.3615 | 0.3615 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0212 | 0.134 | 0.2253 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0042 | 0.0004 | 0.0007 |
Echinococcus multilocularis | histone acetyltransferase myst3 | 0.0062 | 0.0165 | 0.0277 |
Schistosoma mansoni | chromobox protein | 0.0302 | 0.2047 | 0.2047 |
Toxoplasma gondii | PLU-1 family protein | 0.0067 | 0.0204 | 1 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0042 | 0.0004 | 0.0008 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0423 | 0.3004 | 0.58 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0042 | 0.0004 | 0.0007 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0042 | 0.0004 | 0.0007 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0147 | 0.0828 | 0.16 |
Echinococcus granulosus | voltage gated potassium channel | 0.0061 | 0.0157 | 0.0264 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0589 | 0.4308 | 0.4308 |
Brugia malayi | mbt repeat family protein | 0.0423 | 0.3004 | 0.58 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0147 | 0.0828 | 0.1392 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0042 | 0.0004 | 0.0004 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0042 | 0.0004 | 0.0004 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0175 | 0.1049 | 0.1762 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0042 | 0.0004 | 0.0007 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0212 | 0.134 | 0.2253 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0407 | 0.2874 | 0.483 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0042 | 0.0004 | 0.0008 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0142 | 0.0795 | 0.0795 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0042 | 0.0004 | 0.0008 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0061 | 0.0157 | 0.0264 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0198 | 0.1231 | 1 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0045 | 0.0025 | 0.5 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0042 | 0.0004 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.112 | 0.2164 |
Loa Loa (eye worm) | MBCTL1 | 0.0147 | 0.0828 | 0.16 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0212 | 0.134 | 0.2588 |
Loa Loa (eye worm) | hypothetical protein | 0.07 | 0.5179 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.0004 | 0.0004 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0142 | 0.0795 | 0.0795 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0119 | 0.0608 | 0.1022 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0147 | 0.0828 | 0.1392 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.07 | 0.5179 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0828 | 0.16 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0042 | 0.0004 | 0.0007 |
Echinococcus granulosus | tumor suppressor p53 binding protein 1 | 0.0501 | 0.3615 | 0.6074 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0407 | 0.2874 | 0.2874 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0061 | 0.0157 | 0.0264 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0407 | 0.2874 | 0.2874 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0198 | 0.1231 | 1 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0798 | 0.5951 | 1 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0589 | 0.4308 | 0.7239 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0061 | 0.0157 | 0.0157 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0042 | 0.0004 | 0.0007 |
Brugia malayi | mbt repeat family protein | 0.07 | 0.5179 | 1 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0042 | 0.0004 | 0.0004 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0175 | 0.1049 | 0.1762 |
Echinococcus granulosus | histone acetyltransferase myst3 | 0.0062 | 0.0165 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0004 | 0.0008 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0061 | 0.0157 | 0.0304 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0061 | 0.0157 | 0.0264 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0407 | 0.2874 | 0.483 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0589 | 0.4308 | 0.7239 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0212 | 0.134 | 0.2588 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0157 | 0.0304 |
Echinococcus multilocularis | tumor suppressor p53 binding protein 1 | 0.0501 | 0.3615 | 0.6074 |
Brugia malayi | jmjC domain containing protein | 0.021 | 0.1324 | 0.2556 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0042 | 0.0004 | 0.0007 |
Echinococcus granulosus | chromobox protein 2 | 0.0302 | 0.2047 | 0.3441 |
Echinococcus multilocularis | chromobox protein 2 | 0.0302 | 0.2047 | 0.3441 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0042 | 0.0004 | 0.0007 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0147 | 0.0828 | 0.1392 |
Schistosoma mansoni | phd finger protein | 0.0062 | 0.0165 | 0.0165 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0042 | 0.0004 | 0.0007 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.