Detailed information for compound 1738186

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 448.925 | Formula: C23H17ClN4O2S
  • H donors: 2 H acceptors: 3 LogP: 6.26 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccccc1c1c(C#N)c(N)nc2c1c(N)c(s2)C(=O)c1ccc(cc1)Cl
  • InChi: 1S/C23H17ClN4O2S/c1-2-30-16-6-4-3-5-14(16)17-15(11-25)22(27)28-23-18(17)19(26)21(31-23)20(29)12-7-9-13(24)10-8-12/h3-10H,2,26H2,1H3,(H2,27,28)
  • InChiKey: HUXLUQPBHIGMRV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi olfactory channel protein osm-9 0.0088 0.0253 0.0761
Trypanosoma cruzi hypothetical protein, conserved 0.0788 0.3328 1
Mycobacterium tuberculosis Conserved protein 0.0041 0.0046 0.0046
Schistosoma mansoni transient receptor potential channel 4 0.0085 0.024 0.9414
Brugia malayi Transient-receptor-potential like protein 0.0085 0.024 0.0721
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Entamoeba histolytica alpha/beta hydrolase fold protein, putative 0.003 0 0.5
Schistosoma mansoni voltage-dependent calcium channel 0.0085 0.024 0.9414
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0085 0.024 0.0721
Echinococcus multilocularis transient receptor potential cation channel 0.0085 0.024 0.0721
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0085 0.024 0.0721
Mycobacterium tuberculosis Probable haloalkane dehalogenase 0.0041 0.0046 0.0046
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0085 0.024 0.0721
Echinococcus multilocularis sn1 specific diacylglycerol lipase beta 0.0788 0.3328 1
Echinococcus granulosus calcium activated potassium channel 0.0085 0.024 0.0721
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0085 0.024 1
Echinococcus granulosus potassium voltage gated channel protein 0.0085 0.024 0.0721
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0085 0.024 0.9414
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0085 0.024 0.0721
Mycobacterium leprae Probable exported protease 0.003 0 0.5
Echinococcus multilocularis potassium voltage gated channel protein 0.0085 0.024 0.0721
Toxoplasma gondii hypothetical protein 0.0085 0.024 1
Mycobacterium leprae Probable exported protease 0.003 0 0.5
Mycobacterium leprae POSSIBLE SECRETED PROTEASE 0.003 0 0.5
Loa Loa (eye worm) voltage-gated potassium channel 0.0085 0.024 0.0721
Echinococcus granulosus hyperpolarization activated cyclic 0.0085 0.024 0.0721
Echinococcus granulosus voltage dependent calcium channel 0.0085 0.024 0.0721
Echinococcus multilocularis abhydrolase domain containing protein 11 0.0088 0.0255 0.0766
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0085 0.024 0.0721
Echinococcus multilocularis conserved hypothetical protein 0.0085 0.024 0.0721
Echinococcus multilocularis voltage dependent calcium channel 0.0085 0.024 0.0721
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0085 0.024 0.9414
Echinococcus multilocularis shaker cognate 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated ion channel 0.0085 0.024 0.9414
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0085 0.024 0.0721
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0085 0.024 0.0721
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0085 0.024 0.0721
Mycobacterium tuberculosis 4,9-DHSA hydrolase 0.2276 0.9866 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Echinococcus granulosus transient receptor potential cation channel 0.0088 0.0253 0.0761
Echinococcus multilocularis transient receptor potential cation channel 0.0085 0.024 0.0721
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0085 0.024 0.9414
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0085 0.024 0.0721
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Leishmania major hypothetical protein, unknown function 0.0085 0.024 0.0721
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0085 0.024 0.9414
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0085 0.024 0.0721
Leishmania major hypothetical protein, conserved 0.0068 0.0167 0.0501
Onchocerca volvulus 0.0085 0.024 0.0721
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0085 0.024 0.0721
Echinococcus multilocularis sodium leak channel non selective protein 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0085 0.024 0.0721
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0085 0.024 0.0721
Mycobacterium tuberculosis Possible haloalkane dehalogenase 0.0041 0.0046 0.0046
Giardia lamblia ENC6 protein 0.003 0 0.5
Echinococcus granulosus sodium channel protein 0.0085 0.024 0.0721
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0085 0.024 0.0721
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0085 0.024 0.0721
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0085 0.024 0.0721
Loa Loa (eye worm) voltage-dependent calcium channel 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Echinococcus multilocularis two pore calcium channel protein 2 0.0085 0.024 0.0721
Schistosoma mansoni hypothetical protein 0.0085 0.024 0.9414
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0085 0.024 0.0721
Mycobacterium ulcerans hydrolase 0.0068 0.0167 0.0167
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0085 0.024 0.9414
Loa Loa (eye worm) voltage-gated calcium channel 0.0085 0.024 0.0721
Plasmodium falciparum alpha/beta hydrolase, putative 0.0088 0.0255 1
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.003 0 0.5
Schistosoma mansoni voltage-gated cation channel 0.0085 0.024 0.9414
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0085 0.024 0.0721
Loa Loa (eye worm) ion channel NompC 0.0085 0.024 0.0721
Echinococcus granulosus voltage dependent calcium channel 0.0085 0.024 0.0721
Loa Loa (eye worm) calcium channel 0.0085 0.024 0.0721
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0085 0.024 0.0721
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0085 0.024 0.9414
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0085 0.024 0.0721
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Schistosoma mansoni ryanodine receptor related 0.0085 0.024 0.9414
Echinococcus multilocularis potassium large conductance calcium activated 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0085 0.024 0.0721
Echinococcus granulosus potassium voltage gated channel protein 0.0085 0.024 0.0721
Echinococcus multilocularis calcium activated potassium channel 0.0085 0.024 0.0721
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0085 0.024 0.9414
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0085 0.024 0.0721
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0085 0.024 0.0721
Echinococcus multilocularis potassium voltage gated channel protein 0.0085 0.024 0.0721
Echinococcus granulosus hyperpolarization activated cyclic 0.0085 0.024 0.0721
Brugia malayi Cyclic-nucleotide gated cation channel 0.0085 0.024 0.0721
Brugia malayi voltage-dependent calcium channel 0.0085 0.024 0.0721
Trypanosoma brucei lipase domain protein, putative 0.0788 0.3328 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0253 0.0761
Echinococcus multilocularis voltage gated potassium channel 0.0085 0.024 0.0721
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0085 0.024 0.0721
Echinococcus multilocularis sodium channel protein 0.0085 0.024 0.0721
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0085 0.024 0.0721
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Toxoplasma gondii transporter, cation channel family protein 0.0085 0.024 1
Trichomonas vaginalis lipase containing protein, putative 0.0788 0.3328 1
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0085 0.024 0.0721
Mycobacterium tuberculosis Possible hydrolase 0.0068 0.0167 0.0169
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.024 0.0721
Echinococcus multilocularis potassium voltage gated channel protein 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0085 0.024 0.0721
Trypanosoma brucei lipase domain protein, putative 0.0788 0.3328 1
Schistosoma mansoni calcium-activated potassium channel 0.0085 0.024 0.9414
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0085 0.024 0.0721
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0085 0.024 0.0721
Echinococcus multilocularis transient receptor potential cation channel 0.0085 0.024 0.0721
Echinococcus multilocularis short transient receptor potential channel 6 0.0085 0.024 0.0721
Echinococcus multilocularis voltage dependent calcium channel 0.0085 0.024 0.0721
Echinococcus granulosus ryanodine receptor 44f 0.0085 0.024 0.0721
Echinococcus granulosus potassium large conductance calcium activated 0.0085 0.024 0.0721
Echinococcus multilocularis two pore calcium channel protein 1 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Mycobacterium leprae POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE) 0.003 0 0.5
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0085 0.024 0.0721
Echinococcus granulosus short transient receptor potential channel 6 0.0088 0.0253 0.0761
Echinococcus multilocularis transient receptor potential cation channel 0.0088 0.0253 0.0761
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0085 0.024 0.9414
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Brugia malayi Lipase family protein 0.0788 0.3328 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0085 0.024 0.0721
Leishmania major hypothetical protein, conserved 0.0085 0.024 0.0721
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0085 0.024 0.0721
Loa Loa (eye worm) voltage-gated potassium channel 0.0085 0.024 0.0721
Entamoeba histolytica alpha/beta hydrolase domain protein, putative 0.003 0 0.5
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0085 0.024 0.0721
Schistosoma mansoni 60S ribosomal protein L21 0.0085 0.024 0.9414
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Schistosoma mansoni transient receptor potential channel 0.0085 0.024 0.9414
Leishmania major hypothetical protein, conserved 0.0788 0.3328 1
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Brugia malayi cation channel family protein 0.0085 0.024 0.0721
Echinococcus granulosus sn1 specific diacylglycerol lipase beta 0.0788 0.3328 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0085 0.024 0.9414
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0085 0.024 0.0721
Echinococcus granulosus short transient receptor potential channel 6 0.0085 0.024 0.0721
Onchocerca volvulus 0.0788 0.3328 1
Echinococcus granulosus hypothetical protein 0.0085 0.024 0.0721
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0085 0.024 0.0721
Plasmodium vivax alpha/beta hydrolase, putative 0.0088 0.0255 1
Echinococcus multilocularis transient receptor potential gamma protein 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Toxoplasma gondii hypothetical protein 0.0085 0.024 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0085 0.024 0.0721
Echinococcus multilocularis ryanodine receptor 44f 0.0085 0.024 0.0721
Echinococcus granulosus voltage gated hydrogen channel 1 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0085 0.024 0.0721
Echinococcus granulosus abhydrolase domain containing protein 11 0.0088 0.0255 0.0766
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0085 0.024 0.0721
Echinococcus granulosus potassium voltage gated channel protein 0.0085 0.024 0.0721
Schistosoma mansoni family S33 non-peptidase homologue (S33 family) 0.0088 0.0255 1
Entamoeba histolytica hypothetical protein 0.003 0 0.5
Brugia malayi hypothetical protein 0.0085 0.024 0.0721
Echinococcus multilocularis short transient receptor potential channel 6 0.0088 0.0253 0.0761
Echinococcus granulosus shaker cognate 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0085 0.024 0.9414
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Brugia malayi cation channel family protein 0.0085 0.024 0.0721
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0085 0.024 0.9414
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0085 0.024 0.0721
Echinococcus multilocularis potassium voltage gated channel protein 0.0085 0.024 0.0721
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0085 0.024 0.0721
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0068 0.0167 0.0501
Schistosoma mansoni transient receptor potential channel 0.0088 0.0253 0.9944
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0068 0.0167 0.0501
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0085 0.024 0.0721
Trypanosoma cruzi hypothetical protein, conserved 0.0788 0.3328 1
Echinococcus granulosus two pore calcium channel protein 1 0.0085 0.024 0.0721
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0085 0.024 0.0721
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0085 0.024 0.9414
Trichomonas vaginalis lipase containing protein, putative 0.0788 0.3328 1
Schistosoma mansoni vesicular amine transporter 0.0085 0.024 0.9414
Toxoplasma gondii transporter, cation channel family protein 0.0085 0.024 1
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0085 0.024 0.0721
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0085 0.024 0.9414
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0085 0.024 0.0721
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0085 0.024 0.0721
Echinococcus granulosus voltage gated potassium channel 0.0085 0.024 0.0721
Echinococcus granulosus sodium leak channel non selective protein 0.0085 0.024 0.0721
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0085 0.024 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0255 0.0766
Echinococcus multilocularis transient receptor potential cation channel 0.0085 0.024 0.0721
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.024 0.0721
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0085 0.024 0.9414
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Echinococcus multilocularis transfer RNA-Gly 0.0085 0.024 0.0721
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0085 0.024 0.0721
Echinococcus granulosus transient receptor potential gamma protein 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0085 0.024 0.9414
Loa Loa (eye worm) ryanodine receptor 0.0085 0.024 0.0721
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0068 0.0167 0.0501
Echinococcus granulosus TRP transient receptor potential channel 0.0085 0.024 0.0721
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0085 0.024 0.0721
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0085 0.024 0.0721
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Echinococcus multilocularis voltage gated potassium channel 0.0085 0.024 0.0721
Echinococcus multilocularis transient receptor potential cation channel 0.0088 0.0253 0.0761
Mycobacterium tuberculosis Probable oxidoreductase 0.0041 0.0046 0.0046
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0085 0.024 0.9414
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0085 0.024 0.0721
Schistosoma mansoni transient receptor potential channel 0.0085 0.024 0.9414
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.024 0.0721
Echinococcus granulosus potassium voltage gated channel protein 0.0085 0.024 0.0721
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Loa Loa (eye worm) hypothetical protein 0.0085 0.024 0.0721
Echinococcus granulosus potassium voltage gated channel protein 0.0085 0.024 0.0721
Echinococcus granulosus voltage gated potassium channel 0.0085 0.024 0.0721
Echinococcus granulosus two pore calcium channel protein 2 0.0085 0.024 0.0721
Loa Loa (eye worm) lipase 0.0788 0.3328 1
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0085 0.024 0.0721
Toxoplasma gondii transporter, cation channel family protein 0.0085 0.024 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0085 0.024 0.0721
Mycobacterium leprae Probable homoserine o-acetyltransferase MetA 0.003 0 0.5
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0085 0.024 0.9414
Brugia malayi ion channel NompC 0.0085 0.024 0.0721
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.024 0.9414
Echinococcus granulosus transient receptor potential cation channel 0.0085 0.024 0.0721
Schistosoma mansoni two-pore calcium channel 0.0085 0.024 0.9414
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0085 0.024 0.0721
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0068 0.0167 0.6947
Brugia malayi hydrolase, alpha/beta fold family protein 0.0068 0.0167 0.0501
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0085 0.024 0.0721

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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