Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0336 | 0.3634 | 0.5 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0256 | 0.2539 | 0.2539 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.012 | 0.0666 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0336 | 0.3634 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Schistosoma mansoni | RNA binding protein | 0.012 | 0.0666 | 0.1834 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.012 | 0.0666 | 0.1834 |
Onchocerca volvulus | 0.0182 | 0.153 | 0.2987 | |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.012 | 0.0666 | 0.0108 |
Brugia malayi | brahma associated protein 60 kDa | 0.0336 | 0.3634 | 1 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0336 | 0.3634 | 0.3634 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.2697 | 0.7351 |
Brugia malayi | protein kinase C II. | 0.0275 | 0.2801 | 0.7709 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Schistosoma mansoni | atypical protein kinase C | 0.0221 | 0.206 | 0.5669 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.3634 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0666 | 0.1817 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0275 | 0.2801 | 0.7709 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.06 | 0.1636 |
Brugia malayi | protein kinase C3,putative | 0.0146 | 0.1034 | 0.2847 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0123 | 0.0711 | 0.1937 |
Onchocerca volvulus | 0.012 | 0.0666 | 0.0108 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.012 | 0.0666 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.012 | 0.0666 | 0.5 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.012 | 0.0673 | 0.1835 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0275 | 0.2801 | 0.2801 |
Schistosoma mansoni | zinc finger protein | 0.012 | 0.0666 | 0.1834 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.012 | 0.0666 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.358 | 0.976 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0336 | 0.3634 | 0.3634 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0336 | 0.3634 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0336 | 0.3634 | 0.3634 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.012 | 0.0666 | 1 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0336 | 0.3634 | 1 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0184 | 0.1557 | 0.4285 |
Schistosoma mansoni | protein kinase C mu | 0.0184 | 0.1557 | 0.4285 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0336 | 0.3634 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.0666 | 0.1834 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.0666 | 0.1834 |
Brugia malayi | Protein kinase c protein 2 | 0.0187 | 0.1594 | 0.4388 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0115 | 0.06 | 0.06 |
Entamoeba histolytica | protein kinase, putative | 0.0075 | 0.0055 | 0.0578 |
Onchocerca volvulus | 0.0336 | 0.3634 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.2697 | 0.7351 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0117 | 0.0634 | 0.1745 |
Echinococcus multilocularis | tumor protein p63 | 0.08 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0336 | 0.3634 | 1 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0115 | 0.06 | 0.06 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.0666 | 0.1834 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0275 | 0.2801 | 0.7636 |
Brugia malayi | Protein kinase domain containing protein | 0.0075 | 0.0055 | 0.015 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0256 | 0.2539 | 0.6988 |
Onchocerca volvulus | 0.0118 | 0.0646 | 0.0041 | |
Brugia malayi | YY1-associated factor 2 | 0.012 | 0.0666 | 0.1834 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0666 | 0.1817 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0136 | 0.0889 | 0.0889 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0075 | 0.0055 | 0.0578 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.012 | 0.0666 | 0.0666 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0336 | 0.3634 | 0.3634 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.012 | 0.0666 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Onchocerca volvulus | 0.0268 | 0.2697 | 0.6876 | |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0646 | 0.1762 |
Brugia malayi | brahma associated protein 60 kDa | 0.0336 | 0.3634 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.3634 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.012 | 0.0666 | 1 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0115 | 0.06 | 0.06 |
Schistosoma mansoni | hypothetical protein | 0.012 | 0.0666 | 0.1834 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0666 | 0.1817 |
Chlamydia trachomatis | SWIB complex protein | 0.0336 | 0.3634 | 0.5 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0256 | 0.2539 | 0.2539 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.014 | 0.0944 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0666 | 0.1817 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0336 | 0.3634 | 0.3634 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.3634 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0634 | 0.1728 |
Echinococcus granulosus | protein kinase C gamma type | 0.0192 | 0.1656 | 0.1656 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0184 | 0.1557 | 0.4244 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.012 | 0.0666 | 0.1834 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0336 | 0.3634 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0192 | 0.1656 | 0.1656 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.012 | 0.0666 | 0.0666 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.012 | 0.0666 | 0.0666 |
Onchocerca volvulus | 0.012 | 0.0666 | 0.0108 | |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0336 | 0.3634 | 0.9905 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0336 | 0.3634 | 0.3634 |
Schistosoma mansoni | brg-1 associated factor | 0.0336 | 0.3634 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.153 | 0.417 |
Echinococcus granulosus | ring and YY1 binding protein | 0.012 | 0.0666 | 0.0666 |
Onchocerca volvulus | 0.0186 | 0.1584 | 0.3168 | |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.0152 | 0.1115 | 0.3039 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.3669 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0666 | 0.1817 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.2697 | 0.7351 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0256 | 0.2539 | 0.6988 |
Trichomonas vaginalis | AGC family protein kinase | 0.0075 | 0.0055 | 0.015 |
Onchocerca volvulus | 0.012 | 0.0666 | 0.0108 | |
Brugia malayi | C1-like domain containing protein | 0.0184 | 0.1557 | 0.4285 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.1484 | 0.4045 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.012 | 0.0666 | 0.0666 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Toxoplasma gondii | ran binding protein | 0.012 | 0.0666 | 0.1834 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0077 | 0.0083 | 0.0229 |
Schistosoma mansoni | fusion | 0.012 | 0.0666 | 0.1834 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.012 | 0.0666 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.012 | 0.0666 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0646 | 0.1762 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1584 | 0.4319 |
Onchocerca volvulus | 0.012 | 0.0666 | 0.0108 | |
Chlamydia trachomatis | DNA topoisomerase I | 0.0336 | 0.3634 | 0.5 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0075 | 0.0055 | 0.0149 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0275 | 0.2801 | 0.2801 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.012 | 0.0666 | 0.1834 |
Echinococcus granulosus | protein kinase c iota type | 0.0215 | 0.1979 | 0.1979 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.012 | 0.0666 | 0.5 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.012 | 0.0666 | 0.0666 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.012 | 0.0666 | 0.5 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.012 | 0.0666 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.0215 | 0.1979 | 0.1979 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.012 | 0.0666 | 0.0666 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0336 | 0.3634 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0205 | 0.1834 | 0.1834 |
Loa Loa (eye worm) | brahma associated protein | 0.0336 | 0.3634 | 0.9905 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.012 | 0.0666 | 0.0666 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.