Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | biogenic amine synthesis related protein 1 | 0.0169 | 0.0971 | 0.0971 |
Trichomonas vaginalis | group II pyridoxal-5-phosphate decarboxylase, putative | 0.0169 | 0.0971 | 0.5 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0063 | 0.0239 | 0.0239 |
Brugia malayi | glutamate decarboxylase putative | 0.0169 | 0.0971 | 0.0971 |
Brugia malayi | Pyridoxal-dependent decarboxylase conserved domain containing protein | 0.0169 | 0.0971 | 0.0971 |
Mycobacterium ulcerans | glutamate decarboxylase | 0.0169 | 0.0971 | 0.5 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0 | 0.5 |
Brugia malayi | Aromatic-L-amino-acid decarboxylase | 0.0169 | 0.0971 | 0.0971 |
Entamoeba histolytica | s phingosine-1-phosphate lyase 1, putative | 0.1481 | 1 | 0.5 |
Echinococcus granulosus | snurportin 1 | 0.0303 | 0.1889 | 0.1889 |
Loa Loa (eye worm) | glutamate decarboxylase GAD1 | 0.0169 | 0.0971 | 0.0971 |
Echinococcus multilocularis | pyridoxal dependent decarboxylase | 0.0169 | 0.0971 | 0.0971 |
Echinococcus multilocularis | sphingosine 1 phosphate lyase 1 | 0.1481 | 1 | 1 |
Echinococcus granulosus | sphingosine 1 phosphate lyase 1 | 0.1481 | 1 | 1 |
Leishmania major | sphingosine 1-phosphate lyase | 0.1481 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1481 | 1 | 1 |
Trypanosoma brucei | sphingosine 1-phosphate lyase, putative | 0.1481 | 1 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.036 | 0.036 |
Trypanosoma cruzi | sphingosine 1-phosphate lyase, putative | 0.1481 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0096 | 0.0462 | 0.0462 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0063 | 0.0239 | 0.0239 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0096 | 0.0462 | 0.0462 |
Echinococcus granulosus | aromatic amino acid decarboxylase | 0.0169 | 0.0971 | 0.0971 |
Echinococcus multilocularis | snurportin 1 | 0.0303 | 0.1889 | 0.1889 |
Schistosoma mansoni | transient receptor potential channel | 0.0096 | 0.0462 | 0.0462 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0303 | 0.1889 | 0.1889 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.0971 | 0.0971 |
Schistosoma mansoni | hypothetical protein | 0.0303 | 0.1889 | 0.1889 |
Echinococcus multilocularis | aromatic amino acid decarboxylase | 0.0169 | 0.0971 | 0.0971 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0063 | 0.0239 | 0.0239 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0092 | 0.044 | 0.044 |
Mycobacterium tuberculosis | Probable glutamate decarboxylase GadB | 0.0169 | 0.0971 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0218 | 0.0218 |
Loa Loa (eye worm) | aromatic L-amino acid decarboxylase | 0.0169 | 0.0971 | 0.0971 |
Brugia malayi | Transient-receptor-potential like protein | 0.0036 | 0.0049 | 0.0049 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0092 | 0.044 | 0.044 |
Echinococcus granulosus | pyridoxal dependent decarboxylase | 0.0169 | 0.0971 | 0.0971 |
Mycobacterium ulcerans | glutamate decarboxylase | 0.0169 | 0.0971 | 0.5 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0063 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | TDC-1 protein | 0.0169 | 0.0971 | 0.0971 |
Schistosoma mansoni | transient receptor potential channel | 0.0063 | 0.0239 | 0.0239 |
Trypanosoma brucei | Pyridoxal-dependent decarboxylase conserved domain containing protein, putative | 0.0169 | 0.0971 | 0.0971 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0036 | 0.0049 | 0.0049 |
Schistosoma mansoni | phenylalanine decarboxylase | 0.0169 | 0.0971 | 0.0971 |
Loa Loa (eye worm) | sphingosine-1-phosphate lyase 1 | 0.0169 | 0.0971 | 0.0971 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0027 | 0.0027 |
Schistosoma mansoni | phenylalanine decarboxylase | 0.0169 | 0.0971 | 0.0971 |
Schistosoma mansoni | phenylalanine decarboxylase | 0.0169 | 0.0971 | 0.0971 |
Schistosoma mansoni | sphingosine phosphate lyase | 0.1481 | 1 | 1 |
Schistosoma mansoni | phenylalanine decarboxylase | 0.0169 | 0.0971 | 0.0971 |
Brugia malayi | glutamate decarboxylase, 67 kDa isoform | 0.0169 | 0.0971 | 0.0971 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0036 | 0.0049 | 0.0049 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0096 | 0.0462 | 0.0462 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0 | 0.5 |
Schistosoma mansoni | transient receptor potential channel | 0.0063 | 0.0239 | 0.0239 |
Trypanosoma cruzi | sphingosine 1-phosphate lyase, putative | 0.1481 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0462 | 0.0462 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.