Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.0216 | 0.0216 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.7209 | 1 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0021 | 0.0313 | 0.0313 |
Onchocerca volvulus | 0.0089 | 0.1891 | 0.4122 | |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0025 | 0.0404 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0078 | 0.0077 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0078 | 0.0078 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0155 | 0.3431 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0078 | 0.0078 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0078 | 0.0078 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.1532 | 0.1532 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0078 | 0.0084 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0039 | 0.0742 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0742 | 0.5049 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0313 | 0.0313 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.0216 | 0.0216 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.0216 | 0.0388 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0025 | 0.0404 | 0.1812 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0039 | 0.0742 | 0.0742 |
Echinococcus granulosus | GPCR family 2 | 0.0034 | 0.0614 | 0.0614 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0078 | 0.0077 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0078 | 0.0084 |
Onchocerca volvulus | Huntingtin homolog | 0.0131 | 0.2871 | 0.6349 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0025 | 0.0404 | 0.0587 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0035 | 0.0645 | 0.1336 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0078 | 0.0084 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0614 | 0.0614 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0078 | 0.0078 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0078 | 0.0078 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0039 | 0.0742 | 0.0411 |
Schistosoma mansoni | lipoxygenase | 0.0126 | 0.2757 | 0.2757 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0614 | 0.1286 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.2871 | 0.6378 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0078 | 0.0084 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0025 | 0.0404 | 0.5 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.0216 | 0.0394 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0089 | 0.1891 | 0.4172 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0078 | 0.0078 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0.0742 | 0.5474 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1532 | 0.3357 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0078 | 0.0077 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0078 | 0.0078 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0537 | 0.1119 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.02 | 0.4477 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.7209 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0078 | 0.0077 |
Onchocerca volvulus | 0.0031 | 0.0537 | 0.1044 | |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0078 | 0.0084 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.1891 | 0.4168 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0078 | 0.0077 |
Brugia malayi | Doublecortin family protein | 0.0021 | 0.0313 | 0.0614 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.7209 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0078 | 0.0078 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0578 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.2323 | 0.5141 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0313 | 0.0608 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0614 | 0.0614 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0078 | 0.0084 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0126 | 0.2757 | 0.2757 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.0216 | 0.0216 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0025 | 0.0404 | 0.1964 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0313 | 0.0614 |
Schistosoma mansoni | lipoxygenase | 0.0088 | 0.1874 | 0.1874 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0614 | 0.0614 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0044 | 0.0044 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0078 | 0.0078 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.0742 | 0.0742 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0078 | 0.0084 |
Onchocerca volvulus | 0.02 | 0.4477 | 1 | |
Echinococcus multilocularis | RUN | 0.0021 | 0.0313 | 0.0313 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0078 | 0.0078 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0078 | 0.0078 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0025 | 0.0404 | 0.1812 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0317 | 0.7209 | 0.6613 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0021 | 0.0313 | 0.5165 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0313 | 0.0313 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0078 | 0.0078 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0039 | 0.0742 | 0.0742 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0078 | 0.0077 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0078 | 0.0078 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0078 | 0.0078 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0073 | 0.1532 | 0.3361 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0078 | 0.0084 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0025 | 0.0404 | 0.1964 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0078 | 0.0077 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0078 | 0.0078 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0078 | 0.0078 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.0614 | 0.1291 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0078 | 0.0077 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0078 | 0.0077 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0317 | 0.7209 | 0.8294 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0614 | 0.0614 |
Echinococcus multilocularis | GPCR, family 2 | 0.0034 | 0.0614 | 0.0614 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0062 | 0.1257 | 0.0797 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0313 | 0.0313 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0138 | 0.3042 | 0.8791 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0078 | 0.0077 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.02 | 0.4477 | 0.4964 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0317 | 0.7209 | 0.8294 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0578 | 0.0578 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0313 | 0.0313 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0578 | 0.0578 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0313 | 0.0313 |
Onchocerca volvulus | 0.0021 | 0.0313 | 0.0535 | |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0317 | 0.7209 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0537 | 0.1113 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0078 | 0.0078 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.7209 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0437 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.7209 | 1 |
Giardia lamblia | DNA repair protein RAD52 | 0.0377 | 0.8608 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0078 | 0.0077 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0062 | 0.1257 | 0.0797 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0078 | 0.0084 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0078 | 0.0077 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0078 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0313 | 0.0608 |
Trypanosoma brucei | low molecular weight protein tyrosine phosphatase, putative | 0.0062 | 0.1257 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0078 | 0.0084 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0614 | 0.0614 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0155 | 0.3431 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0078 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.2871 | 0.6378 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.02 | 0.4477 | 0.5776 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0614 | 0.0614 |
Entamoeba histolytica | DNA repair and recombination protein RAD52, putative | 0.0377 | 0.8608 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0107 | 0.2322 | 0.2338 |
Onchocerca volvulus | Huntingtin homolog | 0.0131 | 0.2871 | 0.6349 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.7209 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0107 | 0.2323 | 0.5141 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.0614 | 0.1291 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0078 | 0.0078 |
Leishmania major | hypothetical protein, conserved | 0.0062 | 0.1257 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0537 | 0.0537 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0078 | 0.0078 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0216 | 0.0216 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.7209 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.02 | 0.4477 | 0.5776 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.02 | 0.4477 | 0.5776 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0078 | 0.0084 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.02 | 0.4477 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.0614 | 0.1286 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0078 | 0.0084 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0021 | 0.0313 | 0.5165 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0035 | 0.0645 | 0.0796 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0089 | 0.1891 | 0.1891 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0078 | 0.0077 |
Echinococcus granulosus | RUN | 0.0021 | 0.0313 | 0.0313 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0078 | 0.0084 |
Onchocerca volvulus | 0.0021 | 0.0313 | 0.0535 | |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0078 | 0.0078 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0078 | 0.0084 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0078 | 0.0084 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0089 | 0.1891 | 0.1891 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.02 | 0.4477 | 0.4964 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0078 | 0.0078 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0614 | 0.0614 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0078 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0078 | 0.0077 |
Schistosoma mansoni | loxhd1 | 0.0021 | 0.0313 | 0.0313 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0742 | 0.5049 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0044 | 0.0044 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.1176 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0062 | 0.1257 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.1338 | 0.1338 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0313 | 0.0313 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0216 | 0.0216 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0317 | 0.7209 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0078 | 0.0084 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0078 | 0.0078 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0216 | 0.0216 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0062 | 0.1257 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0437 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0078 | 0.0084 |
Loa Loa (eye worm) | inositol-1 | 0.0039 | 0.0742 | 0.1574 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0126 | 0.2757 | 0.2757 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.02 | 0.4477 | 0.5776 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.0216 | 0.0394 |
Entamoeba histolytica | Rad52/22 family double-strand break repair protein, putative | 0.0107 | 0.2322 | 0.2338 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.02 | 0.4477 | 0.5776 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0742 | 0.5049 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.02 | 0.4477 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.0742 | 0.0742 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0089 | 0.1891 | 0.1891 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.02 | 0.4477 | 0.5776 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0078 | 0.0078 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0078 | 0.0078 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0107 | 0.2323 | 0.5144 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0107 | 0.2323 | 0.5144 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0578 | 0.0578 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0078 | 0.0078 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0078 | 0.0078 |
Brugia malayi | Inositol-1 | 0.0039 | 0.0742 | 0.158 |
Loa Loa (eye worm) | doublecortin family protein | 0.0021 | 0.0313 | 0.0608 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0078 | 0.0077 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0313 | 0.0313 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0155 | 0.3431 | 0.7431 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0614 | 0.0614 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0025 | 0.0404 | 1 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0021 | 0.0313 | 0.0313 |
Brugia malayi | hypothetical protein | 0.0131 | 0.2871 | 0.638 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0742 | 0.5049 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0039 | 0.0742 | 0.0828 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0078 | 0.0084 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0313 | 0.0614 |
Schistosoma mansoni | polycystin 1-related | 0.0021 | 0.0313 | 0.0313 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0078 | 0.0078 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 213.8 pmol/min | Agonist activity at Periplaneta americana (American cockroach) thoracic nerve cord octopaminergic receptor assessed as induction of adenylate cyclase-mediated cAMP production per mg protein at 100 uM by radioimmunoassay | ChEMBL. | No reference |
Ka (binding) | = 0.19 uM | Agonist activity at Periplaneta americana (American cockroach) thoracic nerve cord octopaminergic receptor assessed as induction of adenylate cyclase-mediated cAMP production per mg protein by radioimmunoassay | ChEMBL. | No reference |
max activation (binding) | = 19.9 % | Agonist activity at Periplaneta americana (American cockroach) thoracic nerve cord octopaminergic receptor assessed as induction of adenylate cyclase-mediated cAMP production per mg protein at 100 uM by radioimmunoassay relative to octopamine | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.