TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 255.111 | Formula: C10H11BrN2O
H donors: 1 H acceptors: 0 LogP: 2.61 Rotable bonds: 1
Rule of 5 violations (Lipinski): 1
SMILES: Brc1ccc(c(c1)C)/N=C\1/NCCO1
InChi: 1S/C10H11BrN2O/c1-7-6-8(11)2-3-9(7)13-10-12-4-5-14-10/h2-3,6H,4-5H2,1H3,(H,12,13)
InChiKey: FUCHLMIIONRHTD-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0011	0.0078	0.0078
Brugia malayi	photoreceptor-specific nuclear receptor	0.0011	0.0078	0.0084
Echinococcus multilocularis	lipoxygenase domain containing protein	0.0021	0.0313	0.0313
Toxoplasma gondii	4'-phosphopantetheinyl transferase domain-containing protein	0.0025	0.0404	0.1964
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0011	0.0078	0.0078
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.02	0.4477	0.5776
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0011	0.0078	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0073	0.1532	0.3357
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0065	0.1338	0.1338
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0317	0.7209	1
Brugia malayi	isocitrate dehydrogenase	0.0017	0.0216	0.0394
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0031	0.0537	0.1113
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0107	0.2323	0.5144
Echinococcus granulosus	lipoxygenase domain containing protein	0.0021	0.0313	0.0313
Echinococcus granulosus	Polycystic kidney disease protein	0.0021	0.0313	0.0313
Echinococcus multilocularis	RUN	0.0021	0.0313	0.0313
Brugia malayi	Doublecortin family protein	0.0021	0.0313	0.0614
Plasmodium falciparum	holo-[acyl-carrier-protein] synthase, putative	0.0025	0.0404	1
Echinococcus multilocularis	FTZ F1 alpha	0.0011	0.0078	0.0078
Brugia malayi	Latrophilin receptor protein 2	0.0034	0.0614	0.1291
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0011	0.0078	0.0084
Trypanosoma cruzi	hypothetical protein, conserved	0.0062	0.1257	1
Trypanosoma brucei	hypothetical protein, conserved	0.0025	0.0404	0.1812
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0011	0.0078	0.0084
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0011	0.0078	0.0077
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0011	0.0078	0.0078
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0317	0.7209	0.8294
Schistosoma mansoni	lipoxygenase	0.0088	0.1874	0.1874
Loa Loa (eye worm)	hypothetical protein	0.0131	0.2871	0.6378
Brugia malayi	hypothetical protein	0.0021	0.0313	0.0614
Leishmania major	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0039	0.0742	0.5049
Mycobacterium ulcerans	extragenic suppressor protein SuhB	0.0039	0.0742	0.0828
Brugia malayi	Inositol-1	0.0039	0.0742	0.158
Entamoeba histolytica	myo-inositol monophosphatase, putative	0.0039	0.0742	0.0411
Onchocerca volvulus	Huntingtin homolog	0.0131	0.2871	0.6349
Echinococcus granulosus	inositol monophosphatase 1	0.0039	0.0742	0.0742
Schistosoma mansoni	cpg binding protein	0.0031	0.0537	0.0537
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0011	0.0078	0.0078
Echinococcus granulosus	ecdysone induced protein 78C	0.0011	0.0078	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0313	0.0608
Onchocerca volvulus		0.0089	0.1891	0.4122
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0614	0.1286
Echinococcus multilocularis	dnaJ subfamily B	0.0437	1	1
Schistosoma mansoni	rab6-interacting	0.0021	0.0313	0.0313
Loa Loa (eye worm)	phosphotyrosine protein phosphatase	0.02	0.4477	1
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0034	0.0614	0.0614
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0317	0.7209	1
Schistosoma mansoni	hypothetical protein	0.0034	0.0614	0.0614
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0107	0.2323	0.5144
Schistosoma mansoni	rab6-interacting	0.0021	0.0313	0.0313
Schistosoma mansoni	hypothetical protein	0.0034	0.0614	0.0614
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0078	0.0077
Onchocerca volvulus		0.0021	0.0313	0.0535
Loa Loa (eye worm)	hypothetical protein	0.0089	0.1891	0.4168
Brugia malayi	ecdysteroid receptor	0.0011	0.0078	0.0084
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0034	0.0614	0.0614
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0011	0.0078	0.0078
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0011	0.0078	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0078	0.0077
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0317	0.7209	0.8294
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0011	0.0078	0.0084
Schistosoma mansoni	hypothetical protein	0.0034	0.0614	0.0614
Echinococcus granulosus	GPCR family 2	0.0034	0.0614	0.0614
Echinococcus multilocularis	lipoxygenase domain containing protein	0.0021	0.0313	0.0313
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0011	0.0078	0.0084
Echinococcus granulosus	RUN	0.0021	0.0313	0.0313
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0039	0.0742	0.5049
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0062	0.1257	0.0797
Brugia malayi	CXXC zinc finger family protein	0.0031	0.0537	0.1119
Mycobacterium tuberculosis	Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase)	0.0138	0.3042	0.8791
Giardia lamblia	Fructose-bisphosphate aldolase	0.0317	0.7209	0.6613
Brugia malayi	Steroid receptor seven-up type 2	0.0011	0.0078	0.0084
Brugia malayi	latrophilin 2 splice variant baaae	0.0073	0.1532	0.3361
Entamoeba histolytica	hypothetical protein	0.0107	0.2322	0.2338
Schistosoma mansoni	hypothetical protein	0.0021	0.0313	0.0313
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0011	0.0078	0.0084
Schistosoma mansoni	thyroid hormone receptor	0.0011	0.0078	0.0078
Echinococcus multilocularis	cpg binding protein	0.0032	0.0578	0.0578
Schistosoma mansoni	cpg binding protein	0.0032	0.0578	0.0578
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0011	0.0078	0.0078
Mycobacterium leprae	Probable fructose bisphosphate aldolase Fba	0.0155	0.3431	1
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0058	0.1176	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0011	0.0078	0.0078
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0011	0.0078	0.0078
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0011	0.0078	0.0084
Schistosoma mansoni	cpg binding protein	0.0032	0.0578	0.0578
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0011	0.0078	0.0078
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0011	0.0078	0.0084
Mycobacterium tuberculosis	Probable fructose-bisphosphate aldolase Fba	0.0155	0.3431	1
Mycobacterium tuberculosis	Inositol-1-monophosphatase SuhB	0.0035	0.0645	0.1336
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0317	0.7209	1
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0011	0.0078	0.0078
Onchocerca volvulus		0.0021	0.0313	0.0535
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0078	0.0077
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0078	0.0077
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0034	0.0614	0.1286
Echinococcus granulosus	L aminoadipate semialdehyde	0.0089	0.1891	0.1891
Onchocerca volvulus	Huntingtin homolog	0.0131	0.2871	0.6349
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0011	0.0078	0.0077
Loa Loa (eye worm)	hypothetical protein	0.0131	0.2871	0.6378
Entamoeba histolytica	DNA repair and recombination protein RAD52, putative	0.0377	0.8608	1
Schistosoma mansoni	retinoic acid receptor RXR	0.0011	0.0078	0.0078
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0062	0.1257	0.0797
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	0.0017	0.0216	0.0216
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0317	0.7209	1
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.02	0.4477	0.5776
Onchocerca volvulus		0.0031	0.0537	0.1044
Schistosoma mansoni	polycystin 1-related	0.0021	0.0313	0.0313
Trypanosoma brucei	low molecular weight protein tyrosine phosphatase, putative	0.0062	0.1257	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0011	0.0078	0.0077
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0078	0.0077
Brugia malayi	nuclear receptor NHR-88	0.0011	0.0078	0.0084
Loa Loa (eye worm)	isocitrate dehydrogenase	0.0017	0.0216	0.0388
Leishmania major	phosphopantetheinyl transferase-like protein	0.0025	0.0404	0.1812
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.02	0.4477	0.4964
Loa Loa (eye worm)	inositol-1	0.0039	0.0742	0.1574
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.02	0.4477	0.5776
Toxoplasma gondii	4'-phosphopantetheinyl transferase superfamily protein	0.0025	0.0404	0.1964
Plasmodium vivax	holo-[acyl-carrier-protein] synthase, putative	0.0025	0.0404	1
Schistosoma mansoni	nuclear hormone receptor	0.0011	0.0078	0.0078
Loa Loa (eye worm)	steroid hormone receptor	0.0011	0.0078	0.0077
Entamoeba histolytica	Rad52/22 family double-strand break repair protein, putative	0.0107	0.2322	0.2338
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0317	0.7209	1
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0011	0.0078	0.0084
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0011	0.0078	0.0078
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0034	0.0614	0.1291
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0017	0.0216	0.0216
Echinococcus granulosus	arachidonate 5 lipoxygenase	0.0126	0.2757	0.2757
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.02	0.4477	0.5776
Echinococcus granulosus	lipoxygenase domain containing protein	0.0021	0.0313	0.0313
Echinococcus multilocularis	inositol monophosphatase 1	0.0039	0.0742	0.0742
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0011	0.0078	0.0078
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0011	0.0078	0.0078
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0317	0.7209	1
Schistosoma mansoni	loxhd1	0.0021	0.0313	0.0313
Plasmodium falciparum	LCCL domain-containing protein	0.0021	0.0313	0.5165
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0017	0.0216	0.0216
Brugia malayi	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	0.0089	0.1891	0.4172
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0011	0.0078	0.0084
Schistosoma mansoni	hypothetical protein	0.0437	1	1
Giardia lamblia	DNA repair protein RAD52	0.0377	0.8608	1
Echinococcus multilocularis	L aminoadipate semialdehyde	0.0089	0.1891	0.1891
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0317	0.7209	1
Mycobacterium tuberculosis	holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie	0.0025	0.0404	0.0587
Plasmodium vivax	multidomain scavenger receptor, putative	0.0021	0.0313	0.5165
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.02	0.4477	0.5776
Brugia malayi	hypothetical protein	0.0131	0.2871	0.638
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0313	0.0608
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0011	0.0078	0.0084
Schistosoma mansoni	RAR-like nuclear receptor	0.0011	0.0078	0.0078
Trypanosoma cruzi	hypothetical protein, conserved	0.0062	0.1257	1
Echinococcus multilocularis	ecdysone induced protein 78C	0.0011	0.0078	0.0078
Echinococcus multilocularis	isocitrate dehydrogenase	0.0017	0.0216	0.0216
Loa Loa (eye worm)	doublecortin family protein	0.0021	0.0313	0.0608
Brugia malayi	Nuclear hormone receptor-like 1	0.0011	0.0078	0.0084
Schistosoma mansoni	hypothetical protein	0.0034	0.0614	0.0614
Schistosoma mansoni	aminoadipate-semialdehyde dehydrogenase	0.0089	0.1891	0.1891
Mycobacterium ulcerans	phosphotyrosine protein phosphatase PtpA	0.02	0.4477	1
Treponema pallidum	fructose-bisphosphate aldolase	0.0317	0.7209	1
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0034	0.0614	0.0614
Schistosoma mansoni	hypothetical protein	0.0073	0.1532	0.1532
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0107	0.2323	0.5141
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0078	0.0077
Echinococcus granulosus	cpg binding protein	0.0032	0.0578	0.0578
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0011	0.0078	0.0077
Mycobacterium ulcerans	fructose-bisphosphate aldolase	0.0155	0.3431	0.7431
Schistosoma mansoni	NADP-specific isocitrate dehydrogenase	0.0017	0.0216	0.0216
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0011	0.0078	0.0078
Schistosoma mansoni	inositol monophosphatase	0.0039	0.0742	0.0742
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0009	0.0044	0.0044
Schistosoma mansoni	lipoxygenase	0.0126	0.2757	0.2757
Brugia malayi	steroid hormone receptor	0.0011	0.0078	0.0084
Schistosoma mansoni	coup transcription factor	0.0011	0.0078	0.0078
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0011	0.0078	0.0078
Schistosoma mansoni	thyroid hormone receptor	0.0011	0.0078	0.0078
Brugia malayi	hypothetical protein	0.0021	0.0313	0.0614
Schistosoma mansoni	inositol monophosphatase	0.0039	0.0742	0.0742
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0011	0.0078	0.0078
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0011	0.0078	0.0077
Brugia malayi	nuclear hormone receptor	0.0011	0.0078	0.0084
Brugia malayi	Low molecular weight phosphotyrosine protein phosphatase containing protein	0.02	0.4477	1
Chlamydia trachomatis	holo [acyl-carrier protein] synthase	0.0025	0.0404	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0011	0.0078	0.0084
Echinococcus multilocularis	arachidonate 5 lipoxygenase	0.0126	0.2757	0.2757
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	0.0017	0.0216	0.0216
Echinococcus multilocularis	GPCR, family 2	0.0034	0.0614	0.0614
Mycobacterium leprae	possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ).	0.0035	0.0645	0.0796
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0078	0.0077
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0011	0.0078	0.0078
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0317	0.7209	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0011	0.0078	0.0084
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0011	0.0078	0.0077
Echinococcus multilocularis	Polycystic kidney disease protein	0.0021	0.0313	0.0313
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0011	0.0078	0.0077
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.02	0.4477	0.4964
Wolbachia endosymbiont of Brugia malayi	fructose-1,6-bisphosphatase	0.0039	0.0742	1
Toxoplasma gondii	inositol(myo)-1(or 4)-monophosphatase 2, putative	0.0039	0.0742	0.5474
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0039	0.0742	0.5049
Brugia malayi	Isocitrate dehydrogenase	0.0017	0.0216	0.0394
Onchocerca volvulus		0.02	0.4477	1
Loa Loa (eye worm)	hypothetical protein	0.0107	0.2323	0.5141
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0011	0.0078	0.0078
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0011	0.0078	0.0084
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.02	0.4477	0.5776
Leishmania major	hypothetical protein, conserved	0.0062	0.1257	1
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0017	0.0216	0.0216
Echinococcus granulosus	FTZ F1 alpha	0.0011	0.0078	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0078	0.0077
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0009	0.0044	0.0044
Trypanosoma brucei	inositol-1(or 4)-monophosphatase 1, putative	0.0039	0.0742	0.5049
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0034	0.0614	0.0614
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0011	0.0078	0.0078

Activities

Activity type	Activity value	Assay description	Source	Reference
Activity (binding)	= 213.8 pmol/min	Agonist activity at Periplaneta americana (American cockroach) thoracic nerve cord octopaminergic receptor assessed as induction of adenylate cyclase-mediated cAMP production per mg protein at 100 uM by radioimmunoassay	ChEMBL.	No reference
Ka (binding)	= 0.19 uM	Agonist activity at Periplaneta americana (American cockroach) thoracic nerve cord octopaminergic receptor assessed as induction of adenylate cyclase-mediated cAMP production per mg protein by radioimmunoassay	ChEMBL.	No reference
max activation (binding)	= 19.9 %	Agonist activity at Periplaneta americana (American cockroach) thoracic nerve cord octopaminergic receptor assessed as induction of adenylate cyclase-mediated cAMP production per mg protein at 100 uM by radioimmunoassay relative to octopamine	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2286075

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1806743