TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 368.858 | Formula: C17H25ClN4O3
H donors: 0 H acceptors: 3 LogP: 3.81 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: CCCOC1CC(C)C(=C(N1C)N(Cc1ccc(nc1)Cl)C)[N+](=O)[O-]
InChi: 1S/C17H25ClN4O3/c1-5-8-25-15-9-12(2)16(22(23)24)17(21(15)4)20(3)11-13-6-7-14(18)19-10-13/h6-7,10,12,15H,5,8-9,11H2,1-4H3
InChiKey: NBTTXTORWPUYNU-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	cysteine surface protein, putative	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	conserved hypothetical protein	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0501	0.5335	1
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0501	0.5335	1
Leishmania major	hypothetical protein, conserved	0.0501	0.5335	0.5
Loa Loa (eye worm)	TK protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Entamoeba histolytica	receptor protein kinase, putative	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0501	0.5335	0.5335
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Entamoeba histolytica	hypothetical protein, conserved	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0501	0.5335	0.5335
Loa Loa (eye worm)	TK/EPH protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0501	0.5335	1
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0501	0.5335	0.5
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0501	0.5335	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Entamoeba histolytica	heat shock transcription factor, putative	0.011	0.074	0.002
Loa Loa (eye worm)	hypothetical protein	0.0109	0.0731	0.1371
Brugia malayi	SH2 domain containing protein	0.0501	0.5335	1
Brugia malayi	C-terminal src kinase protein 1	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Echinococcus multilocularis	protein dispatched 1	0.0053	0.0078	0.0078
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Echinococcus granulosus	protein kinase	0.0501	0.5335	1
Schistosoma mansoni	serine/threonine protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0501	0.5335	1
Giardia lamblia	Kinase, NEK	0.0501	0.5335	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	protein kinase	0.0501	0.5335	0.5335
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0501	0.5335	0.5335
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0501	0.5335	0.5335
Schistosoma mansoni	serine/threonine protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Echinococcus granulosus	expressed conserved protein	0.0102	0.0654	0.1225
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0501	0.5335	1
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0501	0.5335	1
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Trichomonas vaginalis	conserved hypothetical protein	0.0501	0.5335	1
Loa Loa (eye worm)	TK/ALK protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0501	0.5335	1
Loa Loa (eye worm)	SRC-1	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0501	0.5335	0.5335
Echinococcus granulosus	tyrosine protein kinase shark	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus granulosus	epidermal growth factor receptor	0.0501	0.5335	1
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0501	0.5335	0.5335
Brugia malayi	HSF-type DNA-binding domain containing protein	0.011	0.074	0.1388
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0501	0.5335	1
Leishmania major	protein kinase, putative	0.0501	0.5335	0.5
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase csk	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0501	0.5335	1
Onchocerca volvulus	Tyrosine kinase homolog	0.0501	0.5335	1
Loa Loa (eye worm)	TK/ABL protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	conserved hypothetical protein	0.0501	0.5335	1
Entamoeba histolytica	heat shock transcription factor, putative	0.011	0.074	0.002
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Echinococcus multilocularis	activated cdc42 kinase 1	0.0501	0.5335	0.5335
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0055	0.0099	0.0185
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0501	0.5335	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0501	0.5335	0.5335
Echinococcus multilocularis	expressed conserved protein	0.0102	0.0654	0.0654
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	hypothetical protein	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Entamoeba histolytica	receptor protein kinase, putative	0.0501	0.5335	1
Brugia malayi	SRC-1	0.0501	0.5335	1
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Leishmania major	protein kinase, putative	0.0501	0.5335	0.5
Loa Loa (eye worm)	serine/threonine protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/DDR protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0501	0.5335	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0501	0.5335	0.5335
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0501	0.5335	0.5
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Echinococcus granulosus	geminin	0.0188	0.1655	0.3102
Brugia malayi	SH2 domain containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0501	0.5335	0.5335
Schistosoma mansoni	serine/threonine protein kinase	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	TK/INSR protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	Guanylyl cyclase protein 23	0.0501	0.5335	1
Echinococcus multilocularis	epidermal growth factor receptor	0.0501	0.5335	0.5335
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Echinococcus multilocularis	Niemann Pick C1 protein	0.0109	0.0731	0.0731
Brugia malayi	protein-tyrosine kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0501	0.5335	1
Onchocerca volvulus	Heat shock factor protein 2 homolog	0.011	0.074	0.1164
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	activin receptor type	0.0501	0.5335	0.5335
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0501	0.5335	0.5335
Loa Loa (eye worm)	aryl Hydrocarbon receptor Associated protein family member	0.0059	0.0138	0.0259
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0501	0.5335	0.5335
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0099	0.0185
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0501	0.5335	0.5
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Entamoeba histolytica	tyrosin kinase, putative	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Trypanosoma brucei	Pseudokinase, putative	0.0501	0.5335	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0501	0.5335	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Echinococcus granulosus	tyrosine kinase	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0501	0.5335	0.5335
Onchocerca volvulus		0.0501	0.5335	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase HCK	0.0501	0.5335	1
Echinococcus granulosus	natriuretic peptide receptor 1	0.0501	0.5335	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0501	0.5335	0.5335
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0501	0.5335	1
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0501	0.5335	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.011	0.074	0.1388
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0501	0.5335	0.5335
Echinococcus multilocularis	FL cytokine receptor	0.0501	0.5335	0.5335
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0501	0.5335	0.5335
Brugia malayi	integrin-linked kinase	0.0501	0.5335	1
Echinococcus granulosus	integrin linked protein kinase	0.0501	0.5335	1
Plasmodium falciparum	protein kinase, putative	0.0501	0.5335	0.5
Trichomonas vaginalis	protein kinase atn1, putative	0.0501	0.5335	1
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0501	0.5335	0.5
Echinococcus granulosus	Niemann Pick C1 protein	0.0109	0.0731	0.1371
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Plasmodium falciparum	protein kinase, putative	0.0501	0.5335	0.5
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	TK protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine kinase	0.0501	0.5335	0.5335
Echinococcus multilocularis	transfer RNA-Thr	0.0501	0.5335	0.5335
Schistosoma mansoni	hypothetical protein	0.0188	0.1655	0.3102
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0501	0.5335	0.5335
Echinococcus multilocularis	epidermal growth factor receptor	0.0501	0.5335	0.5335
Schistosoma mansoni	tyrosine protein kinase	0.0501	0.5335	1
Echinococcus granulosus	tyrosine kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0501	0.5335	0.5335
Trypanosoma cruzi	protein kinase, putative	0.0501	0.5335	0.5
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0501	0.5335	1
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Echinococcus granulosus	tyrosine kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/ROR protein kinase	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK protein kinase	0.0501	0.5335	1
Trypanosoma brucei	protein kinase, putative	0.0501	0.5335	0.5
Echinococcus multilocularis	protein tyrosine kinase	0.0501	0.5335	0.5335
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0501	0.5335	0.5335
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0124	0.0232
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0501	0.5335	0.5335
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Brugia malayi	Tyrosine-protein kinase PR2	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0501	0.5335	1
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0055	0.0099	0.0185
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0501	0.5335	0.5335
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus granulosus	ephrin type A receptor 4 A	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase pr2	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Trichomonas vaginalis	conserved hypothetical protein	0.0501	0.5335	1
Trichomonas vaginalis	STE family protein kinase	0.0501	0.5335	1
Echinococcus granulosus	insulin receptor	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Srms	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Blk	0.0501	0.5335	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0501	0.5335	0.5335
Trichomonas vaginalis	conserved hypothetical protein	0.0501	0.5335	1
Trichomonas vaginalis	CAMK family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase csk	0.0501	0.5335	1
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0501	0.5335	0.5335
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Schistosoma mansoni	protein tyrosine kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0501	0.5335	0.5335
Schistosoma mansoni	niemann-pick C1 (NPC1)	0.0111	0.0751	0.1408
Trichomonas vaginalis	conserved hypothetical protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0501	0.5335	0.5335
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0501	0.5335	1
Plasmodium falciparum	tyrosine kinase-like protein	0.0501	0.5335	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Brugia malayi	Raf kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	TK protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0501	0.5335	1
Echinococcus multilocularis	geminin	0.0188	0.1655	0.1655
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Echinococcus multilocularis	integrin linked protein kinase	0.0501	0.5335	0.5335
Echinococcus multilocularis	insulin receptor	0.0501	0.5335	0.5335
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0501	0.5335	0.5335
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0501	0.5335	0.5335
Giardia lamblia	Kinase	0.0501	0.5335	0.5
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0501	0.5335	1
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	ephrin receptor 1 precursor	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0501	0.5335	0.5335
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Echinococcus granulosus	c src tyrosine kinase	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0501	0.5335	0.5335
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Giardia lamblia	Kinase, NEK	0.0501	0.5335	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	hypothetical protein	0.0501	0.5335	1
Toxoplasma gondii	protein kinase	0.0501	0.5335	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FAK protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Echinococcus granulosus	activin receptor type	0.0501	0.5335	1
Trichomonas vaginalis	conserved hypothetical protein	0.0501	0.5335	1
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/RYK protein kinase	0.0501	0.5335	1
Entamoeba histolytica	tyrosin kinase, putative	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0501	0.5335	1
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0055	0.0099	0.0185
Plasmodium falciparum	tyrosine kinase-like protein	0.0501	0.5335	0.5
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	AGC family protein kinase	0.0501	0.5335	1
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0501	0.5335	1
Loa Loa (eye worm)	TK/Met protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0501	0.5335	0.5335
Plasmodium vivax	protein kinase, putative	0.0501	0.5335	0.5
Echinococcus granulosus	Niemann Pick C1 protein	0.0156	0.1281	0.2401
Echinococcus granulosus	aryl hydrocarbon receptor	0.0059	0.0138	0.0259
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0501	0.5335	0.5335
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0501	0.5335	1
Entamoeba histolytica	protein kinase, putative	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus granulosus	protein tyrosine kinase	0.0501	0.5335	1
Schistosoma mansoni	hypothetical protein	0.0188	0.1655	0.3102
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	TK protein kinase	0.0501	0.5335	1
Trypanosoma cruzi	protein kinase, putative	0.0501	0.5335	0.5
Echinococcus granulosus	activated cdc42 kinase 1	0.0501	0.5335	1
Brugia malayi	hypothetical protein	0.0058	0.0135	0.0253
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0501	0.5335	1
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK/CSK protein kinase	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Echinococcus granulosus	raf serine:threonine protein kinase	0.0501	0.5335	1
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0501	0.5335	0.5335
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Toxoplasma gondii	STE kinase	0.0501	0.5335	0.5
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	TK protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine kinase	0.0501	0.5335	0.5335
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0501	0.5335	0.5
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0501	0.5335	0.5335
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0501	0.5335	0.5335
Echinococcus multilocularis	tyrosine protein kinase shark	0.0501	0.5335	0.5335
Giardia lamblia	Protein 21.1	0.0501	0.5335	0.5
Brugia malayi	hypothetical protein	0.0501	0.5335	1
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase	0.0501	0.5335	0.5335
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	TK/ACK protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0501	0.5335	1
Echinococcus multilocularis	protein kinase	0.0501	0.5335	0.5335
Entamoeba histolytica	tyrosin kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0058	0.0135	0.0253
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Entamoeba histolytica	hypothetical protein	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0501	0.5335	1
Echinococcus multilocularis	heat shock protein 70	0.0501	0.5335	0.5335
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0501	0.5335	0.5335
Echinococcus granulosus	receptor type guanylyl cyclase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0501	0.5335	1
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Echinococcus granulosus	kinase suppressor of Ras 1	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Echinococcus multilocularis	Niemann Pick C1 protein	0.0156	0.1281	0.1281
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0501	0.5335	0.5335
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Schistosoma mansoni	protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0501	0.5335	0.5335
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Loa Loa (eye worm)	TK protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	ankyrin repeat protein	0.0501	0.5335	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0501	0.5335	1
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0501	0.5335	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0501	0.5335	0.5335
Brugia malayi	Niemann-Pick C1 protein precursor	0.0109	0.0731	0.1371
Loa Loa (eye worm)	TK protein kinase	0.0501	0.5335	1
Schistosoma mansoni	hypothetical protein	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0501	0.5335	0.5
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Loa Loa (eye worm)	hypothetical protein	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0501	0.5335	0.5335
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0501	0.5335	0.5
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0501	0.5335	0.5
Brugia malayi	Tyrosine-protein kinase abl-1	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Onchocerca volvulus		0.0501	0.5335	1
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Brugia malayi	Furin-like cysteine rich region family protein	0.0501	0.5335	1
Echinococcus multilocularis	aryl hydrocarbon receptor	0.0059	0.0138	0.0138
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Entamoeba histolytica	protein kinase domain containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Schistosoma mansoni	serine/threonine RGC	0.0501	0.5335	1
Echinococcus granulosus	tyrosine protein kinase csk	0.0501	0.5335	1
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0501	0.5335	1
Echinococcus granulosus	activated cdc42 kinase 1	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0501	0.5335	0.5335
Schistosoma mansoni	ephrin receptor	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0501	0.5335	0.5335
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0501	0.5335	0.5335
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0501	0.5335	1
Entamoeba histolytica	ankyrin repeat protein	0.0501	0.5335	1
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Trichomonas vaginalis	TKL family protein kinase	0.0501	0.5335	1
Brugia malayi	Protein kinase domain containing protein	0.0501	0.5335	1
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0501	0.5335	0.5
Entamoeba histolytica	tyrosin kinase, putative	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0501	0.5335	0.5335
Entamoeba histolytica	heat shock transcription factor, putative	0.011	0.074	0.002
Toxoplasma gondii	protein kinase domain-containing protein	0.0501	0.5335	0.5
Echinococcus granulosus	tyrosine protein kinase	0.0501	0.5335	1
Schistosoma mansoni	ephrin receptor	0.0501	0.5335	1
Trichomonas vaginalis	TK family protein kinase	0.0501	0.5335	1
Plasmodium falciparum	protein kinase, putative	0.0501	0.5335	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0501	0.5335	1
Brugia malayi	Receptor family ligand binding region containing protein	0.0501	0.5335	1
Echinococcus multilocularis	c src tyrosine kinase	0.0501	0.5335	0.5335
Echinococcus granulosus	epidermal growth factor receptor	0.0501	0.5335	1
Schistosoma mansoni	tyrosine kinase	0.0501	0.5335	1
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0501	0.5335	1
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0501	0.5335	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2228837

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1810584