TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 226.232 | Formula: C9H14N4O3
H donors: 1 H acceptors: 3 LogP: -0.25 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: CN/N=C(/C1C(=O)N(C)C(=O)N(C1=O)C)\C
InChi: 1S/C9H14N4O3/c1-5(11-10-2)6-7(14)12(3)9(16)13(4)8(6)15/h6,10H,1-4H3/b11-5+
InChiKey: VFBOGZBMWBKVPD-VZUCSPMQSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0544	0.5453	1
Echinococcus granulosus	tyrosine kinase	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Giardia lamblia	Kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/ABL protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0544	0.5453	0.5434
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0544	0.5453	1
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0544	0.5453	0.5434
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0544	0.5453	1
Loa Loa (eye worm)	TK/ALK protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/ACK protein kinase	0.0544	0.5453	1
Brugia malayi	protein-tyrosine kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	protein tyrosine kinase	0.0544	0.5453	0.5434
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0544	0.5453	1
Entamoeba histolytica	hypothetical protein	0.0544	0.5453	0.8859
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0544	0.5453	0.5434
Entamoeba histolytica	tyrosin kinase, putative	0.0544	0.5453	0.8859
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Toxoplasma gondii	protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	protein kinase	0.0544	0.5453	0.5434
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Entamoeba histolytica	hypothetical protein	0.0544	0.5453	0.8859
Echinococcus multilocularis	integrin linked protein kinase	0.0544	0.5453	0.5434
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0544	0.5453	1
Brugia malayi	hypothetical protein	0.0544	0.5453	1
Loa Loa (eye worm)	TK/RYK protein kinase	0.0544	0.5453	1
Leishmania major	protein kinase, putative	0.0544	0.5453	1
Brugia malayi	CCR4	0.0062	0.0042	0.0076
Echinococcus granulosus	integrin linked protein kinase	0.0544	0.5453	1
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	conserved hypothetical protein	0.0544	0.5453	1
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Entamoeba histolytica	hypothetical protein	0.0544	0.5453	0.8859
Echinococcus granulosus	tyrosine kinase	0.0544	0.5453	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0544	0.5453	0.5434
Onchocerca volvulus		0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0544	0.5453	0.5434
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Brugia malayi	PDZ-domain protein scribble	0.0062	0.0042	0.0076
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0544	0.5453	0.5434
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0544	0.5453	0.5434
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Loa Loa (eye worm)	SRC-1	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0544	0.5453	0.5434
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0062	0.0042	0.0076
Brugia malayi	Protein kinase domain containing protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0544	0.5453	0.8859
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0544	0.5453	0.5434
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0544	0.5453	0.5434
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0544	0.5453	1
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0544	0.5453	0.5434
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0544	0.5453	0.5434
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0544	0.5453	0.5434
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Schistosoma mansoni	serine/threonine protein kinase	0.0544	0.5453	1
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	tyrosin kinase, putative	0.0544	0.5453	0.8859
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0544	0.5453	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Brugia malayi	Guanylyl cyclase protein 23	0.0544	0.5453	1
Schistosoma mansoni	serine/threonine protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	Ras-binding protein SUR-8	0.0062	0.0042	0.0076
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0544	0.5453	1
Schistosoma mansoni	protein tyrosine kinase	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0544	0.5453	0.8859
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	ankyrin repeat protein	0.0544	0.5453	0.8859
Loa Loa (eye worm)	TK protein kinase	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0544	0.5453	1
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0544	0.5453	0.5434
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0544	0.5453	0.5434
Brugia malayi	C-terminal src kinase protein 1	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Echinococcus granulosus	c src tyrosine kinase	0.0544	0.5453	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	sur-8-PB	0.0062	0.0042	0.0076
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0544	0.5453	1
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0544	0.5453	0.5434
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Plasmodium falciparum	protein kinase, putative	0.0544	0.5453	1
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Loa Loa (eye worm)	TK protein kinase	0.0544	0.5453	1
Schistosoma mansoni	serine/threonine RGC	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FAK protein kinase	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Trypanosoma cruzi	protein kinase, putative	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Echinococcus multilocularis	transfer RNA-Thr	0.0544	0.5453	0.5434
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Echinococcus multilocularis	protein kinase	0.0544	0.5453	0.5434
Loa Loa (eye worm)	TK/CSK protein kinase	0.0544	0.5453	1
Echinococcus granulosus	tyrosine kinase	0.0544	0.5453	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0544	0.5453	0.8859
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Echinococcus multilocularis	activated cdc42 kinase 1	0.0544	0.5453	0.5434
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0544	0.5453	1
Leishmania major	hypothetical protein, conserved	0.0544	0.5453	1
Echinococcus granulosus	protein tyrosine kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Schistosoma mansoni	serine/threonine protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Brugia malayi	hypothetical protein	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0544	0.5453	0.5434
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Echinococcus multilocularis	tyrosine protein kinase csk	0.0544	0.5453	0.5434
Giardia lamblia	Kinase, NEK	0.0544	0.5453	1
Echinococcus granulosus	insulin receptor	0.0544	0.5453	1
Loa Loa (eye worm)	TK protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine kinase	0.0544	0.5453	0.5434
Brugia malayi	ras-binding protein SUR-8	0.0062	0.0042	0.0076
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0544	0.5453	0.5434
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	receptor protein kinase, putative	0.0544	0.5453	0.8859
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	TK/INSR protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0544	0.5453	0.5434
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Brugia malayi	Raf kinase	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0062	0.0042	0.0076
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0544	0.5453	1
Giardia lamblia	Kinase, NEK	0.0544	0.5453	1
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Entamoeba histolytica	receptor protein kinase, putative	0.0544	0.5453	0.8859
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	conserved hypothetical protein	0.0544	0.5453	1
Loa Loa (eye worm)	TK protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Echinococcus multilocularis	tyrosine protein kinase	0.0544	0.5453	0.5434
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Brugia malayi	Peroxidasin	0.0062	0.0042	0.0076
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0544	0.5453	1
Brugia malayi	Furin-like cysteine rich region family protein	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0544	0.5453	0.5434
Entamoeba histolytica	hypothetical protein	0.0606	0.6149	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Brugia malayi	ephrin receptor 1 precursor	0.0544	0.5453	1
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	conserved hypothetical protein	0.0544	0.5453	1
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0544	0.5453	1
Loa Loa (eye worm)	TK/ROR protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Brugia malayi	Receptor family ligand binding region containing protein	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	CCR4-NOT transcription complex subunit 6 family protein	0.0062	0.0042	0.0076
Entamoeba histolytica	tyrosin kinase, putative	0.0544	0.5453	0.8859
Echinococcus granulosus	kinase suppressor of Ras 1	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0544	0.5453	1
Schistosoma mansoni	serine/threonine protein kinase	0.0544	0.5453	1
Brugia malayi	Tyrosine-protein kinase PR2	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Entamoeba histolytica	hypothetical protein	0.0544	0.5453	0.8859
Echinococcus multilocularis	activin receptor type	0.0544	0.5453	0.5434
Entamoeba histolytica	serine/threonine kinase, putative	0.0544	0.5453	0.8859
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase HCK	0.0544	0.5453	1
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Echinococcus granulosus	tyrosine protein kinase Srms	0.0544	0.5453	1
Echinococcus multilocularis	epidermal growth factor receptor	0.0544	0.5453	0.5434
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0544	0.5453	0.5434
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase csk	0.0544	0.5453	1
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Plasmodium falciparum	protein kinase, putative	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	FL cytokine receptor	0.0544	0.5453	0.5434
Onchocerca volvulus		0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus granulosus	protein kinase	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase csk	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0544	0.5453	0.5434
Schistosoma mansoni	tyrosine protein kinase	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase Blk	0.0544	0.5453	1
Entamoeba histolytica	hypothetical protein	0.0544	0.5453	0.8859
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Giardia lamblia	Protein 21.1	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase pr2	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	conserved hypothetical protein	0.0544	0.5453	1
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0544	0.5453	1
Echinococcus granulosus	epidermal growth factor receptor	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0544	0.5453	0.5434
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK protein kinase	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Echinococcus granulosus	tyrosine protein kinase shark	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0544	0.5453	0.5434
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	hypothetical protein	0.0544	0.5453	0.8859
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0544	0.5453	0.5434
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0544	0.5453	0.5434
Leishmania major	protein kinase, putative	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase csk	0.0544	0.5453	1
Echinococcus multilocularis	epidermal growth factor receptor	0.0544	0.5453	0.5434
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine kinase	0.0544	0.5453	0.5434
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0544	0.5453	1
Brugia malayi	hypothetical protein	0.0062	0.0042	0.0076
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0544	0.5453	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0544	0.5453	1
Trypanosoma brucei	Pseudokinase, putative	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Loa Loa (eye worm)	TKL/LRRK protein kinase	0.0062	0.0042	0.0076
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0544	0.5453	1
Echinococcus granulosus	receptor type guanylyl cyclase	0.0544	0.5453	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0606	0.6149	1
Entamoeba histolytica	hypothetical protein	0.0544	0.5453	0.8859
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0544	0.5453	1
Echinococcus granulosus	activated cdc42 kinase 1	0.0544	0.5453	1
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0544	0.5453	0.5434
Entamoeba histolytica	serine/threonine kinase, putative	0.0544	0.5453	0.8859
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0544	0.5453	0.5434
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus granulosus	activin receptor type	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Echinococcus granulosus	epidermal growth factor receptor	0.0544	0.5453	1
Entamoeba histolytica	hypothetical protein	0.0544	0.5453	0.8859
Echinococcus granulosus	tyrosine protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Entamoeba histolytica	hypothetical protein	0.0606	0.6149	1
Echinococcus granulosus	activated cdc42 kinase 1	0.0544	0.5453	1
Trypanosoma brucei	protein kinase, putative	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Brugia malayi	hypothetical protein	0.0544	0.5453	1
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0544	0.5453	1
Brugia malayi	Tyrosine-protein kinase abl-1	0.0544	0.5453	1
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0544	0.5453	0.5434
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Trypanosoma cruzi	protein kinase, putative	0.0544	0.5453	1
Echinococcus granulosus	raf serine:threonine protein kinase	0.0544	0.5453	1
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0544	0.5453	0.5434
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0544	0.5453	0.5434
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	PDZ-domain-containing protein scribble	0.0062	0.0042	0.0076
Entamoeba histolytica	ankyrin repeat protein	0.0544	0.5453	0.8859
Echinococcus multilocularis	heat shock protein 70	0.0544	0.5453	0.5434
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0544	0.5453	1
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0544	0.5453	0.5434
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0544	0.5453	0.5434
Brugia malayi	SRC-1	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase shark	0.0544	0.5453	0.5434
Plasmodium falciparum	tyrosine kinase-like protein	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Entamoeba histolytica	hypothetical protein, conserved	0.0544	0.5453	0.8859
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Trichomonas vaginalis	TK family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Echinococcus multilocularis	c src tyrosine kinase	0.0544	0.5453	0.5434
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0544	0.5453	0.5434
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Toxoplasma gondii	STE kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Schistosoma mansoni	ephrin receptor	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	TK/DDR protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0544	0.5453	1
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0544	0.5453	0.5434
Brugia malayi	SH2 domain containing protein	0.0544	0.5453	1
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0544	0.5453	0.5434
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0544	0.5453	0.5434
Trichomonas vaginalis	STE family protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	protein kinase atn1, putative	0.0544	0.5453	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0544	0.5453	1
Schistosoma mansoni	protein kinase	0.0544	0.5453	1
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0544	0.5453	0.5434
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Brugia malayi	SH2 domain containing protein	0.0544	0.5453	1
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Brugia malayi	ras suppressor protein 1	0.0062	0.0042	0.0076
Trichomonas vaginalis	conserved hypothetical protein	0.0544	0.5453	1
Onchocerca volvulus	Tyrosine kinase homolog	0.0544	0.5453	1
Plasmodium vivax	protein kinase, putative	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0544	0.5453	1
Loa Loa (eye worm)	TK protein kinase	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0062	0.0042	0.0076
Entamoeba histolytica	tyrosin kinase, putative	0.0544	0.5453	0.8859
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0544	0.5453	0.5434
Entamoeba histolytica	cysteine surface protein, putative	0.0544	0.5453	0.8859
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0544	0.5453	1
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0544	0.5453	0.5434
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	serine/threonine protein kinase	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Entamoeba histolytica	protein kinase, putative	0.0606	0.6149	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0544	0.5453	1
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Trichomonas vaginalis	conserved hypothetical protein	0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0544	0.5453	1
Loa Loa (eye worm)	TK/Met protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0544	0.5453	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Brugia malayi	EGF-like domain containing protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0544	0.5453	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	TK/EPH protein kinase	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Brugia malayi	integrin-linked kinase	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Toxoplasma gondii	protein kinase domain-containing protein	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Echinococcus granulosus	natriuretic peptide receptor 1	0.0544	0.5453	1
Schistosoma mansoni	hypothetical protein	0.0544	0.5453	1
Echinococcus multilocularis	insulin receptor	0.0544	0.5453	0.5434
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0544	0.5453	1
Brugia malayi	Leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0544	0.5453	1
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0544	0.5453	1
Trichomonas vaginalis	AGC family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Loa Loa (eye worm)	leucine Rich Repeat family protein	0.0062	0.0042	0.0076
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Echinococcus granulosus	ephrin type A receptor 4 A	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0544	0.5453	0.8859
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Brugia malayi	Protein kinase domain containing protein	0.0544	0.5453	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0544	0.5453	1
Onchocerca volvulus		0.0544	0.5453	1
Schistosoma mansoni	ephrin receptor	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Entamoeba histolytica	serine/threonine kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	hypothetical protein	0.0606	0.6149	1
Trichomonas vaginalis	CAMK family protein kinase	0.0544	0.5453	1
Plasmodium falciparum	tyrosine kinase-like protein	0.0544	0.5453	1
Entamoeba histolytica	tyrosine kinase, putative	0.0544	0.5453	0.8859
Entamoeba histolytica	protein kinase domain containing protein	0.0544	0.5453	0.8859
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Plasmodium falciparum	protein kinase, putative	0.0544	0.5453	1
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0544	0.5453	1
Schistosoma mansoni	tyrosine kinase	0.0544	0.5453	1
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0544	0.5453	1
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Loa Loa (eye worm)	hypothetical protein	0.0062	0.0042	0.0076
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Loa Loa (eye worm)	hypothetical protein	0.0544	0.5453	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0544	0.5453	1
Trichomonas vaginalis	TKL family protein kinase	0.0544	0.5453	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0544	0.5453	0.8859
Entamoeba histolytica	protein kinase, putative	0.0544	0.5453	0.8859
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0544	0.5453	0.5434
Trichomonas vaginalis	conserved hypothetical protein	0.0544	0.5453	1
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0544	0.5453	1

Activities

Activity type	Activity value	Assay description	Source	Reference
MIC80 (functional)		Antifungal activity against Candida albicans ATCC 10231 after 48 to 72 hrs by broth microdilution method	ChEMBL.	24361188

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3103755

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1821257