Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | non-receptor protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0692 |
Echinococcus multilocularis | protein tyrosine phosphatase n9 | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Echinococcus granulosus | Receptor type tyrosine protein phosphatase O | 0.0086 | 0.014 | 0.191 |
Brugia malayi | Protein-tyrosine phosphatase 1 | 0.0086 | 0.014 | 0.014 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0156 | 0.0735 | 1 |
Brugia malayi | hypothetical protein | 0.0086 | 0.014 | 0.014 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Schistosoma mansoni | receptor protein tyrosine phosphatase r (pcptp1) | 0.0086 | 0.014 | 0.0692 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0086 | 0.014 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0086 | 0.014 | 0.0692 |
Trichomonas vaginalis | pten, drome, putative | 0.0086 | 0.014 | 0.5 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0086 | 0.014 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0156 | 0.0735 | 0.3626 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0086 | 0.014 | 0.191 |
Echinococcus granulosus | protein tyrosine phosphatase n9 | 0.0086 | 0.014 | 0.191 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Giardia lamblia | Protein tyrosine phosphatase | 0.0086 | 0.014 | 0.5 |
Trypanosoma brucei | protein tyrosine phosphatase 1 | 0.0086 | 0.014 | 1 |
Onchocerca volvulus | 4.1 G protein, putative homolog | 0.0086 | 0.014 | 0.0151 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0086 | 0.014 | 0.191 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0156 | 0.0735 | 1 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0086 | 0.014 | 0.191 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | dual specificity protein phosphatase CDC14B | 0.0086 | 0.014 | 0.0149 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase H | 0.0086 | 0.014 | 0.191 |
Schistosoma mansoni | receptor protein tyrosine phosphatase | 0.0156 | 0.0735 | 0.3626 |
Schistosoma mansoni | receptor protein tyrosine phosphatase n (ia2) | 0.0086 | 0.014 | 0.0692 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0086 | 0.014 | 1 |
Schistosoma mansoni | protein-tyrosine phosphatase n9 | 0.0086 | 0.014 | 0.0692 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Brugia malayi | hypothetical protein | 0.0086 | 0.014 | 0.014 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0156 | 0.0735 | 0.3626 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Echinococcus granulosus | Receptor type tyrosine protein phosphatase O | 0.0086 | 0.014 | 0.191 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Echinococcus multilocularis | hypothetical protein | 0.0086 | 0.014 | 0.191 |
Entamoeba histolytica | Pten 3-phosphoinositide phosphatase, putative | 0.0086 | 0.014 | 0.5 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Brugia malayi | hypothetical protein | 0.0086 | 0.014 | 0.014 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0086 | 0.014 | 0.191 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0086 | 0.014 | 0.191 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Echinococcus multilocularis | 0.0086 | 0.014 | 0.191 | |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0086 | 0.014 | 0.0692 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Leishmania major | protein-tyrosine phosphatase 1-like protein | 0.0086 | 0.014 | 1 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0086 | 0.014 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0086 | 0.014 | 0.0692 |
Brugia malayi | protein-tyrosine phosphatase Lar-like precursor, putative | 0.0086 | 0.014 | 0.014 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0156 | 0.0735 | 0.3626 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0156 | 0.0735 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | protein-tyrosine-phosphatase | 0.0086 | 0.014 | 0.0149 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0086 | 0.014 | 0.0692 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Leishmania major | tyrosine specific protein phosphatase, putative | 0.0086 | 0.014 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0308 | 0.2027 | 1 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0156 | 0.0735 | 0.3626 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0156 | 0.0735 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | hypothetical protein | 0.1174 | 0.9405 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0156 | 0.0735 | 1 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0156 | 0.0735 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Schistosoma mansoni | pcd6 interacting protein-related | 0.0086 | 0.014 | 0.0692 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | protein-tyrosine phosphatase 1 | 0.0086 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.014 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0086 | 0.014 | 0.191 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Loa Loa (eye worm) | protein tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Brugia malayi | hypothetical protein | 0.0086 | 0.014 | 0.014 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Schistosoma mansoni | rgs-gaip interacting protein gipc | 0.0086 | 0.014 | 0.0692 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0156 | 0.0735 | 0.3626 |
Brugia malayi | Dual specificity protein phosphatase CDC14B | 0.0086 | 0.014 | 0.014 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0156 | 0.0735 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Onchocerca volvulus | 0.1158 | 0.9265 | 1 | |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0156 | 0.0735 | 0.0781 |
Schistosoma mansoni | protein-tyrosine phosphatase non-receptor type nt5 | 0.0086 | 0.014 | 0.0692 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | hypothetical protein | 0.1088 | 0.867 | 0.9219 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.1088 | 0.867 | 0.9219 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0086 | 0.014 | 0.0151 | |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.1088 | 0.867 | 0.9219 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0156 | 0.0735 | 1 |
Schistosoma mansoni | receptor protein tyrosine phosphatase n (ia2) | 0.0086 | 0.014 | 0.0692 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0156 | 0.0735 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0086 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0086 | 0.014 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0156 | 0.0735 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0086 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0086 | 0.014 | 1 |
Brugia malayi | hypothetical protein | 0.0086 | 0.014 | 0.014 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0086 | 0.014 | 0.191 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0086 | 0.014 | 0.191 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0086 | 0.014 | 0.191 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0086 | 0.014 | 0.0692 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.014 | 0.0149 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 107.4 % | Induction of Nrf2-dependent HO1 protein level in mouse BV-2 cells at 20 uM after 24 hrs by sandwich ELISA | ChEMBL. | 24467268 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.