Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0027 | 0.0118 | 0.3173 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0076 | 0.0068 |
Onchocerca volvulus | ATP synthase subunit alpha, mitochondrial homolog | 0.0038 | 0.0246 | 0.2031 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0025 | 0.0088 | 0.1596 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0027 | 0.0118 | 0.2056 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4953 |
Giardia lamblia | Vacuolar ATP synthase subunit B | 0.0039 | 0.025 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0024 | 0.0076 | 0.0434 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0024 | 0.0076 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0076 | 0.0068 |
Schistosoma mansoni | nuclear hormone receptor | 0.0024 | 0.0076 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0221 | 0.0595 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0024 | 0.0076 | 0.0068 |
Echinococcus granulosus | Alpha N acetylgalactosaminidase | 0.0119 | 0.1172 | 0.4054 |
Leishmania major | ATPase alpha subunit | 0.0032 | 0.0169 | 0.1767 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0024 | 0.0076 | 0.0019 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0027 | 0.0118 | 0.3173 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0024 | 0.0076 | 0.0068 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4953 |
Echinococcus multilocularis | dna polymerase kappa | 0.0048 | 0.0354 | 0.0298 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0076 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0076 | 0.0068 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0119 | 0.1172 | 0.6681 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0413 | 0.2356 |
Wolbachia endosymbiont of Brugia malayi | ATP synthase F0F1 subunit alpha | 0.0038 | 0.0246 | 1 |
Trypanosoma cruzi | Vacuolar proton pump subunit B, putative | 0.0039 | 0.025 | 0.3056 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.0686 | 0.2288 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.2779 | 0.9903 |
Trichomonas vaginalis | ATP synthase alpha subunit mitochondrial, putative | 0.0039 | 0.025 | 0.2915 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0057 | 0.0451 |
Echinococcus granulosus | ATP synthase subunit alpha mitochondrial | 0.0038 | 0.0246 | 0.0688 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0027 | 0.0118 | 0.3226 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0048 | 0.0354 | 0.4497 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0027 | 0.0118 | 0.3173 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0146 | 0.1484 | 0.1435 |
Echinococcus granulosus | FTZ F1 alpha | 0.0024 | 0.0076 | 0.0068 |
Loa Loa (eye worm) | vacuolar ATP synthase subunit B | 0.0039 | 0.025 | 0.0699 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0024 | 0.0076 | 0.0434 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0024 | 0.0076 | 0.0068 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0024 | 0.0076 | 0.0068 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0027 | 0.0118 | 0.1377 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0077 | 0.0686 | 0.2288 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.1484 | 0.8464 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4953 |
Leishmania major | vacuolar ATP synthase subunit b, putative | 0.0039 | 0.025 | 0.3056 |
Treponema pallidum | V-type ATP synthase subunit B | 0.0039 | 0.025 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0044 | 0.0316 | 0.0941 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0024 | 0.0076 | 0.0068 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0027 | 0.0118 | 0.3226 |
Chlamydia trachomatis | V-type ATP synthase subunit B | 0.0039 | 0.025 | 1 |
Plasmodium falciparum | ATP synthase F1, alpha subunit | 0.0038 | 0.0246 | 0.9833 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.0686 | 0.0633 |
Brugia malayi | vacuolar ATP synthase subunit B | 0.0039 | 0.025 | 0.0699 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0097 | 0.0915 | 0.0862 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0025 | 0.0088 | 0.048 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.2806 | 1 |
Trichomonas vaginalis | ATP synthase, putative | 0.0039 | 0.025 | 0.2915 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0048 | 0.0354 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0024 | 0.0076 | 0.0019 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0088 | 0.0909 |
Brugia malayi | ATP synthase alpha chain, mitochondrial precursor, putative | 0.0038 | 0.0246 | 0.0688 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE ALPHA CHAIN ATPA | 0.0038 | 0.0246 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0057 | 0.0327 |
Brugia malayi | Melibiase family protein | 0.0079 | 0.0717 | 0.24 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0024 | 0.0076 | 0.0434 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0024 | 0.0076 | 0.0434 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0024 | 0.0076 | 0.0068 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0048 | 0.0354 | 0.4953 |
Echinococcus multilocularis | vacuolar ATP synthase subunit b | 0.0039 | 0.025 | 0.0193 |
Trypanosoma brucei | ATP synthase F1, alpha subunit | 0.0032 | 0.0169 | 0.2138 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0024 | 0.0076 | 0.0068 |
Plasmodium vivax | vacuolar ATP synthase subunit b, putative | 0.0039 | 0.025 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0025 | 0.0088 | 0.157 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0024 | 0.0076 | 0.0068 |
Mycobacterium ulcerans | F0F1 ATP synthase subunit alpha | 0.0038 | 0.0246 | 0.6373 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4953 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0048 | 0.0354 | 0.4953 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.0413 | 0.2356 |
Brugia malayi | nuclear hormone receptor | 0.0024 | 0.0076 | 0.0068 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4715 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.017 | 0.1754 | 0.1706 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0079 | 0.0717 | 0.4088 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.0686 | 0.3914 |
Echinococcus granulosus | dna polymerase kappa | 0.0048 | 0.0354 | 0.1079 |
Echinococcus multilocularis | ATPase, H+ transporting, lysosomal accessory | 0.0262 | 0.2806 | 0.2764 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0717 | 0.24 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0146 | 0.1484 | 0.5191 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0024 | 0.0076 | 0.0068 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4715 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0024 | 0.0076 | 0.0434 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0024 | 0.0076 | 0.0434 |
Mycobacterium tuberculosis | Probable ATP synthase alpha chain AtpA | 0.0038 | 0.0246 | 1 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0079 | 0.0717 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0024 | 0.0076 | 0.0068 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0027 | 0.0118 | 0.1011 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.026 | 0.2779 | 0.9903 |
Entamoeba histolytica | V-type ATPase, B subunit, putative | 0.0039 | 0.025 | 0.3056 |
Toxoplasma gondii | vacuolar ATP synthase subunit b, putative | 0.0039 | 0.025 | 0.2131 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0024 | 0.0076 | 0.0068 |
Plasmodium falciparum | V-type proton ATPase subunit B | 0.0039 | 0.025 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0024 | 0.0076 | 0.0434 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0077 | 0.0686 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0024 | 0.0076 | 0.0068 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.026 | 0.2779 | 0.2738 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0077 | 0.0686 | 1 |
Onchocerca volvulus | 0.0097 | 0.0915 | 1 | |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0024 | 0.0076 | 0.0068 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0119 | 0.1172 | 0.6681 |
Schistosoma mansoni | ATP synthase alpha subunit mitochondrial | 0.0038 | 0.0246 | 0.1405 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4953 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0024 | 0.0076 | 0.0068 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0097 | 0.0915 | 0.3119 |
Brugia malayi | polk-prov protein | 0.0036 | 0.0221 | 0.0595 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0024 | 0.0076 | 0.0434 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0024 | 0.0076 | 0.0068 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0024 | 0.0076 | 0.0068 |
Toxoplasma gondii | exonuclease III APE | 0.0022 | 0.0057 | 0.049 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0036 | 0.0221 | 0.2934 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0119 | 0.1172 | 0.1121 |
Leishmania major | ATPase alpha subunit | 0.0032 | 0.0169 | 0.1767 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4953 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0097 | 0.0915 | 0.5216 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0024 | 0.0076 | 0.0068 |
Plasmodium vivax | ATP synthase alpha chain, putative | 0.0038 | 0.0246 | 0.9833 |
Trypanosoma brucei | ATP synthase F1, alpha subunit | 0.0032 | 0.0169 | 0.2138 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.0686 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0024 | 0.0076 | 0.0068 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0024 | 0.0076 | 0.0068 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0027 | 0.0118 | 0.2056 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4953 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0024 | 0.0076 | 0.0068 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0024 | 0.0076 | 0.0068 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0024 | 0.0076 | 0.0019 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0118 | 0.097 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0024 | 0.0076 | 0.0068 |
Schistosoma mansoni | thyroid hormone receptor | 0.017 | 0.1754 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0076 | 0.0068 |
Trypanosoma cruzi | V-type proton ATPase subunit B, putative | 0.0039 | 0.025 | 0.3056 |
Leishmania major | DNA polymerase kappa, putative | 0.0025 | 0.0088 | 0.048 |
Echinococcus granulosus | ATPase H transporting lysosomal accessory | 0.0262 | 0.2806 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0024 | 0.0076 | 0.0068 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0048 | 0.0354 | 0.4497 |
Brugia malayi | hypothetical protein | 0.0262 | 0.2806 | 1 |
Brugia malayi | hypothetical protein | 0.026 | 0.2779 | 0.9903 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.0413 | 0.1294 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0024 | 0.0076 | 0.0068 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.0686 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0024 | 0.0076 | 0.0019 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0024 | 0.0076 | 0.0068 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0027 | 0.0118 | 0.1011 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4953 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0076 | 0.0068 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0057 | 0.0327 |
Brugia malayi | steroid hormone receptor | 0.0024 | 0.0076 | 0.0068 |
Trypanosoma brucei | Vacuolar proton pump subunit B, putative | 0.0039 | 0.025 | 0.3369 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0024 | 0.0076 | 0.0068 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.0686 | 0.2288 |
Brugia malayi | nuclear receptor NHR-88 | 0.0024 | 0.0076 | 0.0068 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0036 | 0.0221 | 0.2934 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0119 | 0.1172 | 0.6681 |
Schistosoma mansoni | ATP synthase subunit beta vacuolar | 0.0039 | 0.025 | 0.1424 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4715 |
Schistosoma mansoni | thyroid hormone receptor | 0.017 | 0.1754 | 1 |
Toxoplasma gondii | melibiase subfamily protein | 0.0119 | 0.1172 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0048 | 0.0354 | 1 |
Echinococcus multilocularis | ATP synthase subunit alpha, mitochondrial | 0.0038 | 0.0246 | 0.019 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0024 | 0.0076 | 0.0019 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0024 | 0.0076 | 0.0068 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0079 | 0.0717 | 0.4088 |
Mycobacterium tuberculosis | Probable ATP synthase beta chain AtpD | 0.0038 | 0.0246 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0024 | 0.0076 | 0.0068 |
Onchocerca volvulus | 0.0053 | 0.0413 | 0.4019 | |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0024 | 0.0076 | 0.0434 |
Treponema pallidum | V-type ATP synthase subunit B | 0.0039 | 0.025 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0266 | 0.3619 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0097 | 0.0915 | 0.3119 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0076 | 0.0068 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0044 | 0.0316 | 0.026 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.0686 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0915 | 0.3119 |
Trypanosoma brucei | unspecified product | 0.004 | 0.0266 | 0.3619 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0024 | 0.0076 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0076 | 0.0068 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0119 | 0.1172 | 0.6681 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4953 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0024 | 0.0076 | 0.0019 |
Schistosoma mansoni | coup transcription factor | 0.0024 | 0.0076 | 0.0434 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0024 | 0.0076 | 0.0019 |
Mycobacterium leprae | PROBABLE ATP SYNTHASE BETA CHAIN ATPD | 0.0038 | 0.0246 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0048 | 0.0354 | 0.4715 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0024 | 0.0076 | 0.0068 |
Echinococcus granulosus | vacuolar ATP synthase subunit b | 0.0039 | 0.025 | 0.0699 |
Brugia malayi | ecdysteroid receptor | 0.0024 | 0.0076 | 0.0068 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0024 | 0.0076 | 0.0019 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0119 | 0.1172 | 0.1121 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0024 | 0.0076 | 0.0068 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0027 | 0.0118 | 0.097 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.