Detailed information for compound 1853649
Basic information
Technical information
- Name: Unnamed compound
- MW: 485.106 | Formula: C20H21ClN2O2S4
-
H donors: 2
H acceptors: 3
LogP: 6.07
Rotable bonds: 10
Rule of 5 violations (Lipinski): 1 - SMILES: CSCC[C@@H](C(=O)O)NC(=S)c1sc(c(c1c1ccc(cc1)Cl)C#N)SC(C)C
- InChi: 1S/C20H21ClN2O2S4/c1-11(2)28-20-14(10-22)16(12-4-6-13(21)7-5-12)17(29-20)18(26)23-15(19(24)25)8-9-27-3/h4-7,11,15H,8-9H2,1-3H3,(H,23,26)(H,24,25)/t15-/m0/s1
- InChiKey: RGBCVVBVGLYIOR-HNNXBMFYSA-N
Network
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Synonyms
No synonyms found for this compound
Targets
Known targets for this compound
| Species | Target name | Source | Bibliographic reference |
|---|---|---|---|
| Homo sapiens | farnesyltransferase, CAAX box, alpha | Starlite/ChEMBL | No references |
Predicted pathogen targets for this compound
By orthology
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model
Ranking Plot
Putative Targets List
| Species | Potential target | Raw | Global | Species |
|---|---|---|---|---|
| Onchocerca volvulus | Atrial natriuretic peptide receptor 3 homolog | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | serine/threonine RGC | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | conserved hypothetical protein | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Echinococcus granulosus | retinal guanylyl cyclase 2 | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Brugia malayi | Furin-like cysteine rich region family protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | protein prenyltransferase alpha subunit | 0.005 | 0.059 | 0.0552 |
| Loa Loa (eye worm) | TK/EPH protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Plasmodium falciparum | protein kinase, putative | 0.0334 | 1 | 1 |
| Toxoplasma gondii | Tyrosine kinase-like (TKL) protein | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Leishmania major | protein kinase, putative | 0.0334 | 1 | 1 |
| Brugia malayi | Tyrosine-protein kinase PR2 | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Plasmodium vivax | prenyltransferase alpha subunit, putative | 0.0193 | 0.533 | 0.5311 |
| Loa Loa (eye worm) | TK protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | SH2 domain containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Brugia malayi | Tyrosine-protein kinase F09A5.2 in chromosome X, putative | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase csk | 0.0334 | 1 | 1 |
| Brugia malayi | bone morphogenetic protein type 1 receptor | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | atrial natriuretic peptide receptor 1 | 0.0334 | 1 | 1 |
| Entamoeba histolytica | leucine-rich repeat domain-containing protein | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | ephrin receptor | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Plasmodium falciparum | tyrosine kinase-like protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0334 | 1 | 1 |
| Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0193 | 0.533 | 0.5311 |
| Plasmodium vivax | tyrosine kinase-like protein, putative | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | basic fibroblast growth factor receptor 1 A | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein, conserved | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Plasmodium vivax | protein kinase, putative | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | receptor type guanylyl cyclase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | SRC-1 | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase | 0.0334 | 1 | 1 |
| Giardia lamblia | Kinase | 0.0334 | 1 | 1 |
| Trypanosoma brucei | STE/STE11 serine/threonine-protein kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | protein tyrosine kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/ALK protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | insulin receptor | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Toxoplasma gondii | Tyrosine kinase-like (TKL) protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | serine/threonine kinase, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/Met protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TKL/MLK/HH498 protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | conserved hypothetical protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Plasmodium falciparum | protein farnesyltransferase subunit alpha | 0.0193 | 0.533 | 0.5037 |
| Loa Loa (eye worm) | TK protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase shark | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Plasmodium vivax | protein prenyltransferase alpha subunit, putative | 0.005 | 0.059 | 0.0552 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | serine/threonine kinase, putative | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | atrial natriuretic peptide receptor 1 | 0.0334 | 1 | 1 |
| Echinococcus granulosus | mitogen-activated protein kinase kinase kinase 9 | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | epidermal growth factor receptor | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosin kinase, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TKL/MLK/ILK protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | serine/threonine kinase, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus granulosus | activated cdc42 kinase 1 | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/DDR protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus granulosus | fibroblast growth factor receptor 4 | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Toxoplasma gondii | calcium dependent protein kinase CDPK8 | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TKL/STKR/TYPE1 protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | conserved hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | protein tyrosine kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Giardia lamblia | Protein 21.1 | 0.0334 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | retinal guanylyl cyclase 2 | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | heat shock protein 70 | 0.0334 | 1 | 1 |
| Echinococcus granulosus | natriuretic peptide receptor 1 | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | serine/threonine kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase csk | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | epidermal growth factor receptor | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | retinal guanylyl cyclase 2 | 0.0334 | 1 | 1 |
| Entamoeba histolytica | serine/threonine kinase, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | br serine/threonine-protein kinase, putative | 0.0334 | 1 | 1 |
| Brugia malayi | proto-oncogene tyrosine-protein kinase FER | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Onchocerca volvulus | Tyrosine kinase receptor Cad96Ca homolog | 0.0334 | 1 | 1 |
| Echinococcus granulosus | insulin receptor | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | retinal guanylyl cyclase 2 | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase csk | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | basic fibroblast growth factor receptor 1 A | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0233 | 0.6666 | 0.6652 |
| Trichomonas vaginalis | serine/threonine-protein kinase wnk, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | macrophage colony stimulating factor 1 receptor | 0.0334 | 1 | 1 |
| Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus granulosus | protein prenyltransferase alpha subunit | 0.005 | 0.059 | 0.059 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | serine/threonine protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine protein kinase fes (fps) (ptk group IV) | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0193 | 0.533 | 0.5037 |
| Echinococcus granulosus | geranylgeranyl transferase type 2 subunit alpha | 0.005 | 0.059 | 0.059 |
| Echinococcus multilocularis | activated cdc42 kinase 1 | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | epidermal growth factor receptor | 0.0334 | 1 | 1 |
| Plasmodium vivax | tyrosine kinase-like protein, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.005 | 0.059 | 0.0552 |
| Plasmodium falciparum | protein kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase with ankyrin repeats, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Plasmodium falciparum | protein kinase, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine-protein kinase fps85d | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | CAMK family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0193 | 0.533 | 0.5037 |
| Trichomonas vaginalis | STE family protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0334 | 1 | 1 |
| Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Srms | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | activated cdc42 kinase 1 | 0.0334 | 1 | 1 |
| Brugia malayi | C-terminal src kinase protein 1 | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | protein KINase family member (kin 25) | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | ephrin type A receptor 4 A | 0.0334 | 1 | 1 |
| Brugia malayi | ephrin receptor 1 precursor | 0.0334 | 1 | 1 |
| Entamoeba histolytica | receptor protein kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Schistosoma mansoni | tyrosine-protein kinase fps85d | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | dual specificity testis specific protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | integrin linked protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | fibroblast growth factor receptor 4 | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | activin receptor type | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosin kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine- protein kinase 2, putative | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | natriuretic peptide receptor 1 | 0.0334 | 1 | 1 |
| Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosin kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus granulosus | raf serine:threonine protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein farnesyltransferase alpha subunit, putative | 0.0193 | 0.533 | 0.5037 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | serine-threonine protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/ROR protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0334 | 1 | 1 |
| Brugia malayi | SH2 domain containing protein | 0.0334 | 1 | 1 |
| Trypanosoma cruzi | protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase HCK | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase transmembrane receptor | 0.0334 | 1 | 1 |
| Brugia malayi | Pre-SET motif family protein | 0.0233 | 0.6666 | 0.6652 |
| Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | raf serine:threonine protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | conserved hypothetical protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Giardia lamblia | Kinase, NEK | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | SRC-1 | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | protein kinase domain-containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | conserved hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | protein farnesyltransferase alpha subunit | 0.0193 | 0.533 | 0.5311 |
| Trypanosoma cruzi | protein kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Plasmodium falciparum | tyrosine kinase-like protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase pr2 | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | integrin linked protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | kinase suppressor of Ras 1 | 0.0334 | 1 | 1 |
| Echinococcus granulosus | dual specificity testis-specific protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine protein kinase fes (fps) (ptk group IV) | 0.0334 | 1 | 1 |
| Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0041 | 0.0041 |
| Echinococcus multilocularis | tyrosine protein kinase csk | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Brugia malayi | Receptor family ligand binding region containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | geranylgeranyl transferase type 2 subunit alpha | 0.005 | 0.059 | 0.0552 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | c src tyrosine kinase | 0.0334 | 1 | 1 |
| Trypanosoma brucei | AGC/RSK family serine/threonine kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | 3'partial|retinal guanylyl cyclase 2 | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase shark | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | serine/threonine protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | serine/threonine kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase csk | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Trypanosoma brucei | Flagellum attachment zone protein 20 | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | cysteine surface protein, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Fes:Fps | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.005 | 0.059 | 0.0552 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Trypanosoma brucei | Pseudokinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | FL cytokine receptor | 0.0334 | 1 | 1 |
| Toxoplasma gondii | hypothetical protein | 0.005 | 0.059 | 0.0552 |
| Echinococcus multilocularis | tyrosine protein kinase transmembrane receptor | 0.0334 | 1 | 1 |
| Schistosoma mansoni | src-type protein tyrosine kinase-related | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0193 | 0.533 | 0.5037 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Giardia lamblia | Rab geranylgeranyltransferase | 0.0193 | 0.533 | 0.5037 |
| Brugia malayi | Adenylate and Guanylate cyclase catalytic domain containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK protein kinase | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | set domain proteins, putative | 0.0265 | 0.7734 | 0.7592 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein farnesyltransferase alpha subunit | 0.0193 | 0.533 | 0.5311 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | protein-tyrosine kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | protein tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Toxoplasma gondii | protein kinase domain-containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TK family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Echinococcus granulosus | tyrosine kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | receptor protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase transmembrane receptor | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase Blk | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase csk | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.533 | 0.5311 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Loa Loa (eye worm) | TK/ABL protein kinase | 0.0334 | 1 | 1 |
| Leishmania major | protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/RYK protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/KIN6 protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Raf kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Onchocerca volvulus | Tyrosine kinase homolog | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase transmembrane receptor | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.0193 | 0.533 | 0.5311 |
| Schistosoma mansoni | protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase csk | 0.0334 | 1 | 1 |
| Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosin kinase, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus granulosus | c src tyrosine kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TKL/RAF/KSR protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/CSK protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | conserved hypothetical protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Guanylyl cyclase protein 23 | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Toxoplasma gondii | STE kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK protein kinase | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Schistosoma mansoni | serine/threonine protein kinase | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0334 | 1 | 1 |
| Schistosoma mansoni | hypothetical protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/ACK protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | macrophage colony stimulating factor 1 receptor | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0265 | 0.7734 | 0.7725 | |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Brugia malayi | Probable tyrosine-protein kinase kin-31 | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | ephrin receptor | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | serine/threonine protein kinase | 0.0334 | 1 | 1 |
| Leishmania major | hypothetical protein, conserved | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/INSR protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | protein kinase atn1, putative | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | protein tyrosine kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Brugia malayi | Probable tyrosine-protein kinase kin-31 | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.005 | 0.059 | 0.0552 | |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | retinal guanylyl cyclase 2 | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.005 | 0.059 | 0.0552 |
| Entamoeba histolytica | hypothetical protein | 0.0334 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0334 | 1 | 1 |
| Toxoplasma gondii | protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | protein farnesyltransferase alpha subunit | 0.0193 | 0.533 | 0.533 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0143 | 0.3671 | 0.3274 |
| Brugia malayi | Protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | conserved hypothetical protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | tyrosine protein kinase Fes:Fps | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TKL/RAF/RAF protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | transfer RNA-Thr | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FAK protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | ankyrin repeat protein | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein kinase domain containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK protein kinase | 0.0334 | 1 | 1 |
| Trypanosoma brucei | protein kinase, putative | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine protein kinase pr2 | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | tyrosine kinase, putative | 0.0334 | 1 | 1 |
| Entamoeba histolytica | protein tyrosine kinase domain-containing protein | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Entamoeba histolytica | ankyrin repeat protein | 0.0334 | 1 | 1 |
| Onchocerca volvulus | 0.0334 | 1 | 1 | |
| Toxoplasma gondii | hypothetical protein | 0.0143 | 0.3671 | 0.3645 |
| Loa Loa (eye worm) | TKL/MLK/TAK1 protein kinase | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | retinal guanylyl cyclase 2 | 0.0334 | 1 | 1 |
| Echinococcus granulosus | epidermal growth factor receptor | 0.0334 | 1 | 1 |
| Brugia malayi | Adenylate and Guanylate cyclase catalytic domain containing protein | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | ephrin type A receptor 4 A | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK protein kinase | 0.0334 | 1 | 1 |
| Schistosoma mansoni | tyrosine kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | TKL family protein kinase | 0.0334 | 1 | 1 |
| Echinococcus multilocularis | kinase suppressor of Ras 1 | 0.0334 | 1 | 1 |
| Echinococcus granulosus | activin receptor type | 0.0334 | 1 | 1 |
| Giardia lamblia | Kinase, NEK | 0.0334 | 1 | 1 |
| Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0334 | 1 | 1 |
| Schistosoma mansoni | serine/threonine protein kinase | 0.0334 | 1 | 1 |
| Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0334 | 1 | 1 |
| Loa Loa (eye worm) | TK/FER protein kinase | 0.0334 | 1 | 1 |
Activities
| Activity type | Activity value | Assay description | Source | Reference |
|---|---|---|---|---|
| IC50 (binding) | = 1.7 uM | Inhibition of recombinant human FTase using dansylated peptide Dansyl-GCAIM as substrate by fluorescence-based assay | ChEMBL. | No reference |
Phenotypes
Whole-cell/tissue/organism interactions
We have no records of whole-cell/tissue assays done with this compound
What does this mean?
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Annotated phenotypes:
We have no manually annotated phenotypes for this drug.
What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by
drugs, or by genetic manipulation of cells (e.g. gene knockouts or
knockdowns) is manually curated from the literature. These
descriptions help to describe the potential of the target for drug
development. If no information is available for this gene or if the
information is incomplete, this may mean that i) the papers
containing this information either appeared after the curation
effort for this organism was carried out or they were inadvertently
missed by curators; or that ii) the curation effort for this
organism has not yet started.
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.
External resources for this compound
- ChEMBL: CHEMBL3133561
Bibliographic References
No literature references available for this target.
If you have references for this compound, please enter them in a user comment (below) or Contact us.