Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | MDM2 proto-oncogene, E3 ubiquitin protein ligase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Receptor type tyrosine protein phosphatase O | 0.0163 | 0.014 | 0.191 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0163 | 0.014 | 0.191 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0163 | 0.014 | 0.191 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0295 | 0.0735 | 1 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | protein-tyrosine phosphatase 1 | 0.0163 | 0.014 | 0.0149 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0295 | 0.0735 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Leishmania major | protein-tyrosine phosphatase 1-like protein | 0.0163 | 0.014 | 1 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Brugia malayi | hypothetical protein | 0.0163 | 0.014 | 0.014 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0163 | 0.014 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0163 | 0.014 | 1 |
Schistosoma mansoni | protein-tyrosine phosphatase n9 | 0.0163 | 0.014 | 0.191 |
Giardia lamblia | Protein tyrosine phosphatase | 0.0163 | 0.014 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | protein tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Schistosoma mansoni | rgs-gaip interacting protein gipc | 0.0163 | 0.014 | 0.191 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0163 | 0.014 | 0.191 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Brugia malayi | Dual specificity protein phosphatase CDC14B | 0.0163 | 0.014 | 0.014 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0295 | 0.0735 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Loa Loa (eye worm) | protein-tyrosine-phosphatase | 0.0163 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0295 | 0.0735 | 1 |
Brugia malayi | Protein-tyrosine phosphatase 1 | 0.0163 | 0.014 | 0.014 |
Echinococcus granulosus | protein tyrosine phosphatase n9 | 0.0163 | 0.014 | 0.191 |
Schistosoma mansoni | pcd6 interacting protein-related | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase H | 0.0163 | 0.014 | 0.191 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0163 | 0.014 | 0.191 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0163 | 0.014 | 0.191 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Echinococcus multilocularis | hypothetical protein | 0.0163 | 0.014 | 0.191 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0295 | 0.0735 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0295 | 0.0735 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Entamoeba histolytica | Pten 3-phosphoinositide phosphatase, putative | 0.0163 | 0.014 | 0.5 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Schistosoma mansoni | receptor protein tyrosine phosphatase r (pcptp1) | 0.0163 | 0.014 | 0.191 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Trypanosoma brucei | protein tyrosine phosphatase 1 | 0.0163 | 0.014 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Brugia malayi | protein-tyrosine phosphatase Lar-like precursor, putative | 0.0163 | 0.014 | 0.014 |
Echinococcus multilocularis | 0.0163 | 0.014 | 0.191 | |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.014 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0295 | 0.0735 | 1 |
Brugia malayi | hypothetical protein | 0.0163 | 0.014 | 0.014 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0163 | 0.014 | 0.5 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0163 | 0.014 | 0.191 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0163 | 0.014 | 0.191 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0163 | 0.014 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0163 | 0.014 | 0.191 |
Schistosoma mansoni | receptor protein tyrosine phosphatase n (ia2) | 0.0163 | 0.014 | 0.191 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Brugia malayi | hypothetical protein | 0.0163 | 0.014 | 0.014 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.2219 | 0.9405 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Trichomonas vaginalis | pten, drome, putative | 0.0163 | 0.014 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0295 | 0.0735 | 1 |
Schistosoma mansoni | receptor protein tyrosine phosphatase | 0.0295 | 0.0735 | 1 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0295 | 0.0735 | 1 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0163 | 0.014 | 1 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0295 | 0.0735 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0163 | 0.014 | 0.191 |
Brugia malayi | hypothetical protein | 0.0163 | 0.014 | 0.014 |
Echinococcus granulosus | Receptor type tyrosine protein phosphatase O | 0.0163 | 0.014 | 0.191 |
Leishmania major | tyrosine specific protein phosphatase, putative | 0.0163 | 0.014 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0163 | 0.014 | 0.191 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Echinococcus multilocularis | protein tyrosine phosphatase n9 | 0.0163 | 0.014 | 0.191 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0295 | 0.0735 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0295 | 0.0735 | 1 |
Schistosoma mansoni | protein-tyrosine phosphatase non-receptor type nt5 | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0163 | 0.014 | 0.191 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0295 | 0.0735 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Onchocerca volvulus | 4.1 G protein, putative homolog | 0.0163 | 0.014 | 0.0151 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.0149 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0163 | 0.014 | 0.191 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.2056 | 0.867 | 0.9219 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | dual specificity protein phosphatase CDC14B | 0.0163 | 0.014 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.2056 | 0.867 | 0.9219 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Brugia malayi | hypothetical protein | 0.0163 | 0.014 | 0.014 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0295 | 0.0735 | 1 |
Schistosoma mansoni | receptor protein tyrosine phosphatase n (ia2) | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0295 | 0.0735 | 0.0781 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0295 | 0.0735 | 1 |
Onchocerca volvulus | 0.2188 | 0.9265 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.2056 | 0.867 | 0.9219 |
Onchocerca volvulus | 0.0163 | 0.014 | 0.0151 | |
Schistosoma mansoni | non-receptor protein-tyrosine phosphatase | 0.0163 | 0.014 | 0.191 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.014 | 0.0149 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0163 | 0.014 | 0.014 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.