Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0231 | 1 | 1 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.0076 | 0.3029 | 1 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.0231 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.3029 | 0.3029 |
Plasmodium falciparum | polyprenol reductase, putative | 0.0076 | 0.3029 | 0.5 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0076 | 0.3029 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0231 | 1 | 0.5 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0231 | 1 | 1 |
Plasmodium vivax | polyprenol reductase, putative | 0.0076 | 0.3029 | 0.5 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.0231 | 1 | 1 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0231 | 1 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0231 | 1 | 1 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.0076 | 0.3029 | 1 |
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0076 | 0.3029 | 0.5 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0076 | 0.3029 | 1 |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.0076 | 0.3029 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0231 | 1 | 1 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0231 | 1 | 1 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.0076 | 0.3029 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 1 | 1 |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.0076 | 0.3029 | 0.5 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.0076 | 0.3029 | 0.3029 |
Onchocerca volvulus | 0.0076 | 0.3029 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.3029 | 0.3029 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0076 | 0.3029 | 1 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.0231 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.