Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Onchocerca volvulus | 0.0167 | 0.1281 | 0.1402 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0093 | 0.0108 | 0.0126 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0167 | 0.1281 | 0.1402 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0716 | 1 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0159 | 0.1165 | 0.1452 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Leishmania major | cathepsin L-like protease | 0.0635 | 0.8702 | 1 |
Echinococcus multilocularis | alpha glucosidase | 0.0129 | 0.0691 | 0.0691 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0635 | 0.8702 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0629 | 0.8617 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Onchocerca volvulus | 0.0167 | 0.1281 | 0.1402 | |
Onchocerca volvulus | 0.0167 | 0.1281 | 0.1402 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0159 | 0.1165 | 0.1339 |
Mycobacterium ulcerans | glycogen branching protein | 0.0272 | 0.2947 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0093 | 0.0108 | 0.0126 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0167 | 0.1281 | 0.091 |
Schistosoma mansoni | alpha-amylase | 0.0129 | 0.0691 | 0.0802 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.2947 | 0.2647 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Giardia lamblia | 1,4-alpha-glucan branching enzyme | 0.0272 | 0.2947 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0167 | 0.1281 | 0.1486 |
Schistosoma mansoni | alpha-amylase | 0.0129 | 0.0691 | 0.0802 |
Leishmania major | cathepsin L-like protease | 0.0635 | 0.8702 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0153 | 0.1069 | 0.1241 |
Schistosoma mansoni | starch branching enzyme II | 0.0272 | 0.2947 | 0.342 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0111 | 0.0407 | 0.0473 |
Brugia malayi | Cathepsin L-like precursor | 0.0167 | 0.1281 | 0.1281 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0167 | 0.1281 | 0.1281 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.1281 | 0.1596 |
Trichomonas vaginalis | amylase, putative | 0.0592 | 0.8024 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0167 | 0.1281 | 0.1281 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0159 | 0.1165 | 0.1452 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0716 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0167 | 0.1281 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0167 | 0.1281 | 0.1281 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Onchocerca volvulus | 0.0504 | 0.6637 | 1 | |
Trypanosoma brucei | glucosidase, putative | 0.0159 | 0.1165 | 0.1339 |
Onchocerca volvulus | 0.0167 | 0.1281 | 0.1402 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0167 | 0.1281 | 0.091 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0208 | 0.1938 | 0.5528 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0159 | 0.1165 | 0.1452 |
Brugia malayi | Alpha amylase, catalytic domain containing protein | 0.0129 | 0.0691 | 0.0691 |
Echinococcus granulosus | cathepsin l1 | 0.0167 | 0.1281 | 0.1281 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0167 | 0.1281 | 0.1596 |
Leishmania major | cathepsin L-like protease | 0.0167 | 0.1281 | 0.0153 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0635 | 0.8702 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0111 | 0.0407 | 0.0508 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Plasmodium vivax | vivapain-2 | 0.0167 | 0.1281 | 1 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0159 | 0.1165 | 0.1165 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0159 | 0.1165 | 0.1339 |
Loa Loa (eye worm) | ctsf protein | 0.0167 | 0.1281 | 0.091 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0159 | 0.1165 | 0.1452 |
Brugia malayi | Cathepsin L-like precursor | 0.0167 | 0.1281 | 0.1281 |
Onchocerca volvulus | 0.0167 | 0.1281 | 0.1402 | |
Onchocerca volvulus | 0.0167 | 0.1281 | 0.1402 | |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0159 | 0.1165 | 0.1165 |
Trichomonas vaginalis | alpha-amylase, putative | 0.0513 | 0.6773 | 0.8441 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0093 | 0.0108 | 0.0126 |
Brugia malayi | Cathepsin L-like precursor | 0.0111 | 0.0407 | 0.0407 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0159 | 0.1165 | 0.1452 |
Onchocerca volvulus | Cathepsin F homolog | 0.0167 | 0.1281 | 0.1402 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0111 | 0.0407 | 0.0508 |
Toxoplasma gondii | alpha amylase, catalytic domain-containing protein | 0.0272 | 0.2947 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Entamoeba histolytica | alpha-amylase family protein | 0.0592 | 0.8024 | 1 |
Brugia malayi | Alpha amylase, catalytic domain containing protein | 0.0129 | 0.0691 | 0.0691 |
Brugia malayi | Cathepsin L-like precursor | 0.0167 | 0.1281 | 0.1281 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0159 | 0.1165 | 0.079 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0159 | 0.1165 | 0.1452 |
Brugia malayi | Cathepsin L-like precursor | 0.0167 | 0.1281 | 0.1281 |
Schistosoma mansoni | alpha-amylase | 0.0129 | 0.0691 | 0.0802 |
Toxoplasma gondii | cathepsin CPL | 0.0167 | 0.1281 | 0.413 |
Schistosoma mansoni | alpha glucosidase | 0.0159 | 0.1165 | 0.1352 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0167 | 0.1281 | 0.1486 |
Brugia malayi | Cathepsin L-like precursor | 0.0167 | 0.1281 | 0.1281 |
Chlamydia trachomatis | 1,4-alpha-glucan branching enzyme | 0.0272 | 0.2947 | 0.5 |
Trichomonas vaginalis | alpha-amylase, putative | 0.0592 | 0.8024 | 1 |
Leishmania major | cathepsin L-like protease | 0.0167 | 0.1281 | 0.0153 |
Toxoplasma gondii | 1,4-alpha-glucan-branching enzyme | 0.0272 | 0.2947 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0716 | 1 | 1 |
Echinococcus granulosus | glucan 14 alpha branching enzyme 1 | 0.0272 | 0.2947 | 0.2947 |
Echinococcus multilocularis | cysteine protease | 0.0167 | 0.1281 | 0.1281 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0159 | 0.1165 | 0.1452 |
Loa Loa (eye worm) | alpha amylase | 0.0129 | 0.0691 | 0.0296 |
Brugia malayi | Cathepsin L-like precursor | 0.0111 | 0.0407 | 0.0407 |
Trichomonas vaginalis | alpha-amylase, putative | 0.0592 | 0.8024 | 1 |
Schistosoma mansoni | alpha-amylase | 0.0129 | 0.0691 | 0.0802 |
Entamoeba histolytica | 1,4-alpha-glucan branching enzyme, putative | 0.0272 | 0.2947 | 0.3672 |
Entamoeba histolytica | oligo-1,6-glucosidase, putative | 0.0129 | 0.0691 | 0.0861 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Onchocerca volvulus | Cathepsin L homolog | 0.0167 | 0.1281 | 0.1402 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0159 | 0.1165 | 0.1452 |
Brugia malayi | 1,4-alpha-glucan branching enzyme | 0.0272 | 0.2947 | 0.2947 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Echinococcus multilocularis | cysteine protease | 0.0167 | 0.1281 | 0.1281 |
Schistosoma mansoni | alpha-glucosidase | 0.0629 | 0.8617 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0167 | 0.1281 | 0.091 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.1281 | 0.091 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.058 | 0.7829 | 0.8997 |
Onchocerca volvulus | 0.0167 | 0.1281 | 0.1402 | |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0093 | 0.0108 | 0.0108 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0635 | 0.8702 | 1 |
Toxoplasma gondii | glycosyltransferase | 0.0272 | 0.2947 | 1 |
Echinococcus multilocularis | geminin | 0.0153 | 0.1069 | 0.1069 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0167 | 0.1281 | 1 |
Echinococcus granulosus | Alpha N acetylgalactosaminidase | 0.0093 | 0.0108 | 0.0108 |
Loa Loa (eye worm) | alpha amylase | 0.0129 | 0.0691 | 0.0296 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0159 | 0.1165 | 0.1452 |
Schistosoma mansoni | hypothetical protein | 0.0153 | 0.1069 | 0.1241 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0635 | 0.8702 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0111 | 0.0407 | 0.0508 |
Entamoeba histolytica | 1,4-alpha-glucan branching enzyme, putative | 0.0272 | 0.2947 | 0.3672 |
Entamoeba histolytica | alpha-amylase family protein | 0.0592 | 0.8024 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0167 | 0.1281 | 0.0153 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0499 | 0.6549 | 0.7525 |
Plasmodium vivax | vivapain-2 | 0.0167 | 0.1281 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trichomonas vaginalis | alpha-amylase, putative | 0.0592 | 0.8024 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0716 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0167 | 0.1281 | 0.091 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0093 | 0.0108 | 0.0126 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0167 | 0.1281 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Trichomonas vaginalis | starch branching enzyme II, putative | 0.0272 | 0.2947 | 0.3672 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0167 | 0.1281 | 0.1281 |
Trichomonas vaginalis | alpha-amylase, putative | 0.0592 | 0.8024 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0159 | 0.1165 | 0.1452 |
Echinococcus granulosus | alpha glucosidase | 0.0129 | 0.0691 | 0.0691 |
Leishmania major | cathepsin L-like protease | 0.0167 | 0.1281 | 0.0153 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0159 | 0.1165 | 0.3724 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0167 | 0.1281 | 0.1472 |
Brugia malayi | cathepsin L-like precursor | 0.0111 | 0.0407 | 0.0407 |
Echinococcus granulosus | geminin | 0.0153 | 0.1069 | 0.1069 |
Echinococcus multilocularis | glucan (1,4 alpha), branching enzyme 1 | 0.0272 | 0.2947 | 0.2947 |
Leishmania major | cathepsin L-like protease | 0.0167 | 0.1281 | 0.0153 |
Trichomonas vaginalis | amylase, putative | 0.0272 | 0.2947 | 0.3672 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0167 | 0.1281 | 0.1281 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Schistosoma mansoni | alpha-amylase | 0.0129 | 0.0691 | 0.0802 |
Mycobacterium leprae | Putative uncharacterized protein ML2045 | 0.0129 | 0.0691 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0167 | 0.1281 | 0.1596 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0093 | 0.0108 | 0.0108 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0167 | 0.1281 | 0.1281 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0167 | 0.1281 | 0.1281 |
Leishmania major | cathepsin L-like protease | 0.0167 | 0.1281 | 0.0153 |
Mycobacterium tuberculosis | 1,4-alpha-glucan branching enzyme GlgB (glycogen branching enzyme) | 0.0272 | 0.2947 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Trichomonas vaginalis | amylase, putative | 0.0592 | 0.8024 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.1281 | 0.1596 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0167 | 0.1281 | 0.1281 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0111 | 0.0407 | 0.0407 |
Echinococcus granulosus | cathepsin l1 | 0.0111 | 0.0407 | 0.0407 |
Leishmania major | cathepsin L-like protease | 0.0635 | 0.8702 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0635 | 0.8702 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0159 | 0.1165 | 0.1165 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0159 | 0.1165 | 0.1452 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.