Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Suppressor of lurcher protein 1 precursor | 0.0072 | 0.0267 | 0.0956 |
Echinococcus multilocularis | laminin | 0.0275 | 0.2795 | 0.2597 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0853 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0348 | 0.3697 | 0.3697 |
Loa Loa (eye worm) | hypothetical protein | 0.0819 | 0.9567 | 0.9567 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0247 | 0.245 | 0.8764 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0267 | 0.0267 |
Brugia malayi | Nematode astacin protease protein 30 | 0.0107 | 0.07 | 0.2504 |
Brugia malayi | Lectin C-type domain containing protein | 0.0072 | 0.0267 | 0.0956 |
Echinococcus granulosus | laminin | 0.0275 | 0.2795 | 0.2597 |
Loa Loa (eye worm) | CUB domain-containing protein | 0.0072 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0275 | 0.2795 | 0.2795 |
Brugia malayi | Fibulin-1 precursor | 0.0275 | 0.2795 | 1 |
Brugia malayi | CUB domain containing protein | 0.0072 | 0.0267 | 0.0956 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.07 | 0.07 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0275 | 0.2795 | 0.5 |
Brugia malayi | CUB domain containing protein | 0.0072 | 0.0267 | 0.0956 |
Loa Loa (eye worm) | hypothetical protein | 0.0247 | 0.245 | 0.245 |
Brugia malayi | CUB domain containing protein | 0.0072 | 0.0267 | 0.0956 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | AStacin protease | 0.0534 | 0.6014 | 0.6014 |
Loa Loa (eye worm) | kelch domain-containing protein family protein | 0.0072 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | CUB domain-containing protein | 0.0072 | 0.0267 | 0.0267 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0853 | 1 | 1 |
Onchocerca volvulus | 0.0107 | 0.07 | 0.1982 | |
Brugia malayi | Kelch motif family protein | 0.0072 | 0.0267 | 0.0956 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0077 | 0.032 | 0.0054 |
Loa Loa (eye worm) | zinc metalloproteinase toh-2 | 0.0107 | 0.07 | 0.07 |
Trypanosoma brucei | serine peptidase, clan SB, family S8-like protein | 0.0072 | 0.0267 | 0.5 |
Schistosoma mansoni | egf-like domain protein | 0.0247 | 0.245 | 0.2242 |
Trypanosoma cruzi | subtilisin-like serine peptidase, putative | 0.0072 | 0.0267 | 0.5 |
Brugia malayi | zinc metalloproteinase toh-2 precursor | 0.0107 | 0.07 | 0.2504 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | lectin C-type domain-containing protein | 0.0072 | 0.0267 | 0.0267 |
Onchocerca volvulus | Putative cubilin | 0.01 | 0.0613 | 0.1584 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0267 | 0.5 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0853 | 1 | 1 |
Brugia malayi | astacin protease protein 30 | 0.0107 | 0.07 | 0.2504 |
Brugia malayi | CUB domain containing protein | 0.0072 | 0.0267 | 0.0956 |
Loa Loa (eye worm) | hypothetical protein | 0.0247 | 0.245 | 0.245 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0267 | 0.0956 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0247 | 0.245 | 0.245 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0267 | 0.0267 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0275 | 0.2795 | 0.5 |
Loa Loa (eye worm) | DPY-31 protein | 0.0107 | 0.07 | 0.07 |
Trypanosoma cruzi | subtilisin-like serine peptidase, putative | 0.0072 | 0.0267 | 0.5 |
Echinococcus multilocularis | fibrillin 1 | 0.0275 | 0.2795 | 0.2597 |
Brugia malayi | Zinc metalloproteinase toh-2 precursor | 0.0107 | 0.07 | 0.2504 |
Brugia malayi | CUB domain containing protein | 0.0072 | 0.0267 | 0.0956 |
Onchocerca volvulus | Arrow homolog | 0.0247 | 0.245 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.01 | 0.0613 | 0.2193 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0267 | 0.0267 |
Brugia malayi | Nematode astacin protease protein 30 | 0.0107 | 0.07 | 0.2504 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0275 | 0.2795 | 0.2795 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0267 | 0.0267 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0077 | 0.032 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0613 | 0.0613 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0275 | 0.2795 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.