TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 519.46 | Formula: C26H21N3O9
H donors: 8 H acceptors: 8 LogP: 0.66 Rotable bonds: 2
Rule of 5 violations (Lipinski): 3
SMILES: OCC1OC(C(C(C1O)O)O)n1c2c(O)cccc2c2c1c1[nH]c3c(c1c1c2c(=O)[nH]c1=O)cccc3O
InChi: 1S/C26H21N3O9/c30-7-12-21(33)22(34)23(35)26(38-12)29-19-9(4-2-6-11(19)32)14-16-15(24(36)28-25(16)37)13-8-3-1-5-10(31)17(8)27-18(13)20(14)29/h1-6,12,21-23,26-27,30-35H,7H2,(H,28,36,37)
InChiKey: BSQFHYQBCYIAKE-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	protein kinase C, alpha	Starlite/ChEMBL	References
Homo sapiens	topoisomerase (DNA) I	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Plasmodium yoelii	Eukaryotic DNA topoisomerase I, DNA binding, putative	Get druggable targets OG5_127702	All targets in OG5_127702
Echinococcus granulosus	protein kinase C gamma type	Get druggable targets OG5_129482	All targets in OG5_129482
Schistosoma japonicum	Protein kinase C gamma type, putative	Get druggable targets OG5_129482	All targets in OG5_129482
Trypanosoma brucei	DNA topoisomerase IB, large subunit	Get druggable targets OG5_127702	All targets in OG5_127702
Plasmodium vivax	topoisomerase I, putative	Get druggable targets OG5_127702	All targets in OG5_127702
Echinococcus multilocularis	Protein kinase C, brain isozyme	Get druggable targets OG5_129482	All targets in OG5_129482
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_129482	All targets in OG5_129482
Candida albicans	protein kinase C similar to S. cerevisiae PKC1 (YBL105C)	Get druggable targets OG5_129482	All targets in OG5_129482
Echinococcus multilocularis	RNA directed DNA polymerase	Get druggable targets OG5_129482	All targets in OG5_129482
Loa Loa (eye worm)	DNA topoisomerase I	Get druggable targets OG5_127702	All targets in OG5_127702
Neospora caninum	hypothetical protein	Get druggable targets OG5_127702	All targets in OG5_127702
Echinococcus granulosus	RNA directed DNA polymerase	Get druggable targets OG5_129482	All targets in OG5_129482
Schistosoma mansoni	DNA topoisomerase type I	Get druggable targets OG5_127702	All targets in OG5_127702
Echinococcus multilocularis	DNA topoisomerase 1	Get druggable targets OG5_127702	All targets in OG5_127702
Leishmania donovani	DNA topoisomerase IB, large subunit	Get druggable targets OG5_127702	All targets in OG5_127702
Schistosoma japonicum	Calcium-dependent protein kinase C, putative	Get druggable targets OG5_129482	All targets in OG5_129482
Plasmodium falciparum	topoisomerase I	Get druggable targets OG5_127702	All targets in OG5_127702
Trypanosoma brucei gambiense	DNA topoisomerase IB, large subunit, putative	Get druggable targets OG5_127702	All targets in OG5_127702
Plasmodium knowlesi	topoisomerase I, putative	Get druggable targets OG5_127702	All targets in OG5_127702
Schistosoma japonicum	IPR000477,RNA-directed DNA polymerase (Reverse transcriptase),domain-containing	Get druggable targets OG5_129482	All targets in OG5_129482
Babesia bovis	DNA topoisomerase	Get druggable targets OG5_127702	All targets in OG5_127702
Schistosoma japonicum	Protein kinase C alpha type, putative	Get druggable targets OG5_129482	All targets in OG5_129482
Brugia malayi	Protein kinase c protein 2	Get druggable targets OG5_129482	All targets in OG5_129482
Schistosoma japonicum	ko:K03163 DNA topoisomerase I, putative	Get druggable targets OG5_127702	All targets in OG5_127702
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_129482	All targets in OG5_129482
Leishmania major	DNA topoisomerase IB, large subunit	Get druggable targets OG5_127702	All targets in OG5_127702
Leishmania infantum	DNA topoisomerase IB, large subunit	Get druggable targets OG5_127702	All targets in OG5_127702
Schistosoma mansoni	DNA topoisomerase type I	Get druggable targets OG5_127702	All targets in OG5_127702
Loa Loa (eye worm)	AGC/PKC/ALPHA protein kinase	Get druggable targets OG5_129482	All targets in OG5_129482
Schistosoma mansoni	serine/threonine protein kinase	Get druggable targets OG5_129482	All targets in OG5_129482
Candida albicans	protein kinase C similar to S. cerevisiae PKC1 (YBL105C)	Get druggable targets OG5_129482	All targets in OG5_129482
Schistosoma mansoni	serine/threonine protein kinase	Get druggable targets OG5_129482	All targets in OG5_129482
Schistosoma japonicum	Protein kinase C alpha type, putative	Get druggable targets OG5_129482	All targets in OG5_129482
Toxoplasma gondii	DNA topoisomerase I, putative	Get druggable targets OG5_127702	All targets in OG5_127702
Echinococcus granulosus	Protein kinase C brain isozyme	Get druggable targets OG5_129482	All targets in OG5_129482
Leishmania mexicana	DNA topoisomerase IB, large subunit	Get druggable targets OG5_127702	All targets in OG5_127702
Theileria parva	DNA topoisomerase I, putative	Get druggable targets OG5_127702	All targets in OG5_127702
Leishmania braziliensis	DNA topoisomerase IB, large subunit	Get druggable targets OG5_127702	All targets in OG5_127702
Schistosoma japonicum	IPR011010,DNA breaking-rejoining enzyme, catalytic core,domain-containing	Get druggable targets OG5_127702	All targets in OG5_127702
Echinococcus granulosus	DNA topoisomerase 1	Get druggable targets OG5_127702	All targets in OG5_127702
Trypanosoma cruzi	DNA topoisomerase IB, large subunit, putative	Get druggable targets OG5_127702	All targets in OG5_127702
Echinococcus multilocularis	telomerase reverse transcriptase subunit	Get druggable targets OG5_129482	All targets in OG5_129482
Cryptosporidium parvum	eukaryotic DNA topoisomerase I	Get druggable targets OG5_127702	All targets in OG5_127702
Echinococcus multilocularis	serine threonine protein kinase	Get druggable targets OG5_129482	All targets in OG5_129482
Plasmodium berghei	topoisomerase I, putative	Get druggable targets OG5_127702	All targets in OG5_127702
Schistosoma mansoni	DNA topoisomerase type I	Get druggable targets OG5_127702	All targets in OG5_127702
Cryptosporidium hominis	DNA topoisomerase I	Get druggable targets OG5_127702	All targets in OG5_127702
Brugia malayi	DNA topoisomerase I	Get druggable targets OG5_127702	All targets in OG5_127702
Candida albicans	likely DNA topoisomerase I similar to S. cerevisiae TOP1 (YOL006C)	Get druggable targets OG5_127702	All targets in OG5_127702
Candida albicans	likely DNA topoisomerase I similar to S. cerevisiae TOP1 (YOL006C)	Get druggable targets OG5_127702	All targets in OG5_127702

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	diacylglycerol kinase theta	0.003	0.0403	0.0302
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0426	0.0326
Loa Loa (eye worm)	hypothetical protein	0.003	0.0403	0.0303
Brugia malayi	diacylglycerol kinase	0.003	0.0403	0.0316
Schistosoma mansoni	serine/threonine protein kinase	0.009	0.1311	0.122
Brugia malayi	protein kinase C II.	0.0042	0.0585	0.051
Schistosoma mansoni	DNA topoisomerase type I	0.0169	0.2526	0.2447
Schistosoma mansoni	protein kinase C mu	0.003	0.0403	0.0302
Entamoeba histolytica	hypothetical protein	0.003	0.0403	1
Brugia malayi	RhoGAP domain containing protein	0.003	0.0403	0.0316
Plasmodium falciparum	topoisomerase I	0.0226	0.3392	0.5
Loa Loa (eye worm)	TKL/LRRK protein kinase	0.0057	0.0817	0.0724
Brugia malayi	RhoGAP domain containing protein	0.003	0.0403	0.0316
Echinococcus multilocularis	C2 calcium dependent membrane targeting	0.0032	0.0426	0.0325
Schistosoma mansoni	unc-13 (munc13)	0.0032	0.0426	0.0325
Trypanosoma cruzi	DNA topoisomerase IB, large subunit, putative	0.0169	0.2526	1
Toxoplasma gondii	diacylglycerol kinase, putative	0.003	0.0403	0.0907
Echinococcus granulosus	N chimaerin	0.003	0.0403	0.0302
Echinococcus multilocularis	serine threonine protein kinase	0.006	0.0853	0.0757
Plasmodium vivax	topoisomerase I, putative	0.0226	0.3392	0.5
Loa Loa (eye worm)	Ras association domain family 1 isoform A	0.003	0.0403	0.0303
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Echinococcus multilocularis	serine:threonine protein kinase MRCK beta	0.003	0.0408	0.0307
Onchocerca volvulus		0.0032	0.0426	1
Entamoeba histolytica	protein kinase, putative	0.001	0.0104	0.2587
Loa Loa (eye worm)	hypothetical protein	0.0048	0.067	0.0575
Schistosoma mansoni	rac gtpase activating protein	0.003	0.0403	0.0302
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.003	0.0403	0.0302
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.003	0.0403	0.0303
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.0403	0.0303
Echinococcus granulosus	DNA topoisomerase 1	0.0226	0.3392	0.3323
Schistosoma mansoni	serine/threonine protein kinase	0.0659	1	1
Loa Loa (eye worm)	CAMK/PKD protein kinase	0.003	0.0408	0.0309
Brugia malayi	Raf kinase	0.0629	0.9542	1
Leishmania major	DNA topoisomerase IB, large subunit	0.0169	0.2526	1
Echinococcus granulosus	Diacylglycerol kinase theta	0.003	0.0403	0.0302
Trypanosoma brucei	DNA topoisomerase type IB small subunit	0.0057	0.0811	0.2918
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Schistosoma mansoni	unc-13 (munc13)	0.0032	0.0426	0.0325
Schistosoma mansoni	DNA topoisomerase type I	0.0169	0.2526	0.2447
Entamoeba histolytica	diacylglycerol kinase, putative	0.003	0.0403	1
Brugia malayi	DNA topoisomerase I	0.0226	0.3392	0.3484
Echinococcus granulosus	Serine/threonine-protein kinase Genghis Khan	0.003	0.0408	0.0307
Loa Loa (eye worm)	AGC/PKC/ETA protein kinase	0.0042	0.0585	0.0489
Loa Loa (eye worm)	AGC/PKC/IOTA protein kinase	0.003	0.0408	0.0309
Echinococcus granulosus	unc 13 munc13	0.0032	0.0426	0.0325
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.037	0.5583	0.5563
Brugia malayi	Ras association domain family 1 isoform A	0.003	0.0403	0.0316
Echinococcus multilocularis	telomerase reverse transcriptase subunit	0.0048	0.067	0.0572
Echinococcus granulosus	myotubularin protein 13	0.003	0.0403	0.0302
Loa Loa (eye worm)	raf kinase	0.0656	0.9951	1
Schistosoma mansoni	hypothetical protein	0.003	0.0403	0.0302
Echinococcus granulosus	RNA directed DNA polymerase	0.0048	0.067	0.0572
Loa Loa (eye worm)	hypothetical protein	0.0078	0.1129	0.104
Loa Loa (eye worm)	hypothetical protein	0.003	0.0403	0.0303
Echinococcus granulosus	protein kinase c iota type	0.0041	0.0562	0.0463
Brugia malayi	protein kinase C3,putative	0.003	0.0408	0.0322
Loa Loa (eye worm)	hypothetical protein	0.003	0.0403	0.0303
Loa Loa (eye worm)	hypothetical protein	0.003	0.0403	0.0303
Echinococcus multilocularis	leucine rich repeat serine:threonine protein	0.0057	0.0817	0.072
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.003	0.0403	0.0302
Brugia malayi	Protein kinase domain containing protein	0.0057	0.0817	0.0755
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Schistosoma mansoni	protein kinase C mu	0.003	0.0408	0.0307
Echinococcus granulosus	protein kinase c eta type	0.003	0.0403	0.0302
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Brugia malayi	Pleckstrin Homology Domain	0.003	0.0403	0.0316
Echinococcus multilocularis	Diacylglycerol kinase theta	0.003	0.0403	0.0302
Loa Loa (eye worm)	hypothetical protein	0.003	0.0403	0.0303
Echinococcus multilocularis	protein kinase c iota type	0.0041	0.0562	0.0463
Echinococcus multilocularis	N chimaerin	0.003	0.0403	0.0302
Trypanosoma brucei	DNA topoisomerase IB, large subunit	0.0169	0.2526	1
Brugia malayi	diacylglycerol kinase	0.003	0.0403	0.0316
Echinococcus granulosus	protein kinase C gamma type	0.006	0.0853	0.0757
Brugia malayi	Variant SH3 domain containing protein	0.003	0.0403	0.0316
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.0403	0.0303
Loa Loa (eye worm)	AGC/PKC/ALPHA protein kinase	0.005	0.0699	0.0604
Brugia malayi	RhoGEF domain containing protein	0.003	0.0403	0.0316
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Entamoeba histolytica	protein kinase, putative	0.001	0.0104	0.2587
Echinococcus multilocularis	Rac GTPase activating protein 1	0.003	0.0403	0.0302
Echinococcus multilocularis	RNA directed DNA polymerase	0.0048	0.067	0.0572
Brugia malayi	Protein kinase domain containing protein	0.003	0.0408	0.0322
Schistosoma mansoni	diacylglycerol kinase theta	0.003	0.0403	0.0302
Schistosoma mansoni	serine/threonine protein kinase	0.003	0.0408	0.0307
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Brugia malayi	C1-like domain containing protein	0.003	0.0408	0.0322
Toxoplasma gondii	DNA topoisomerase I, putative	0.0226	0.3392	1
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Schistosoma mansoni	vav2	0.003	0.0403	0.0302
Echinococcus multilocularis	DNA topoisomerase 1	0.0226	0.3392	0.3323
Loa Loa (eye worm)	RasGEF domain-containing protein	0.003	0.0403	0.0303
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.003	0.0403	0.0303
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.003	0.0403	0.0302
Echinococcus multilocularis	protein kinase c epsilon type	0.0042	0.0585	0.0486
Brugia malayi	Phorbol esters/diacylglycerol binding domain	0.003	0.0408	0.0322
Entamoeba histolytica	protein kinase, putative	0.001	0.0104	0.2587
Schistosoma mansoni	DNA topoisomerase type I	0.0226	0.3392	0.3323
Loa Loa (eye worm)	hypothetical protein	0.003	0.0403	0.0303
Echinococcus multilocularis	protein kinase c eta type	0.003	0.0403	0.0302
Brugia malayi	Protein kinase c protein 2	0.008	0.1157	0.1116
Echinococcus multilocularis	unc 13 (munc13)	0.0032	0.0426	0.0325
Loa Loa (eye worm)	DNA topoisomerase I	0.0226	0.3392	0.3339
Entamoeba histolytica	diacylglycerol kinase, putative	0.003	0.0403	1
Echinococcus granulosus	C2 calcium dependent membrane targeting	0.0032	0.0426	0.0325
Trichomonas vaginalis	serine/threonine-protein kinase sgk, putative	0.001	0.0098	0.9453
Echinococcus granulosus	Protein kinase C brain isozyme	0.009	0.1311	0.122
Trichomonas vaginalis	AGC family protein kinase	0.001	0.0104	1
Echinococcus multilocularis	myotubularin protein 13	0.003	0.0403	0.0302
Schistosoma mansoni	serine/threonine protein kinase	0.0042	0.0585	0.0486
Schistosoma mansoni	protein kinase C	0.0032	0.0426	0.0325
Loa Loa (eye worm)	hypothetical protein	0.003	0.0403	0.0303
Schistosoma mansoni	serine/threonine protein kinase	0.003	0.0408	0.0307
Echinococcus multilocularis	Protein kinase C, brain isozyme	0.009	0.1311	0.122
Echinococcus granulosus	leucine rich repeat serine:threonine protein	0.0058	0.0823	0.0726
Schistosoma mansoni	serine/threonine protein kinase	0.009	0.1311	0.122
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.003	0.0403	0.0302
Schistosoma mansoni	atypical protein kinase C	0.0041	0.0562	0.0463
Loa Loa (eye worm)	hypothetical protein	0.003	0.0403	0.0303
Entamoeba histolytica	protein kinase, putative	0.001	0.0104	0.2587
Echinococcus granulosus	Rac GTPase activating protein 1	0.003	0.0403	0.0302
Echinococcus granulosus	protein kinase c epsilon type	0.0042	0.0585	0.0486
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0659	1	1

Activities

Activity type	Activity value	Assay description	Source	Reference
EC200 (functional)	= 2 uM	Effect on the formation of protein-DNA complex in P388 cells K+/SDS method	ChEMBL.	10340602
EC200 (functional)	= 2 uM	Effect on the formation of protein-DNA complex in P388 cells K+/SDS method	ChEMBL.	10340602
EC50 (functional)	= 3 uM	In vitro activity against topoisomerase-I mediated cleavage of supercoiled pBR322 plasmid DNA	ChEMBL.	10340602
EC50 (functional)	= 3 uM	In vitro activity against topoisomerase-I mediated cleavage of supercoiled pBR322 plasmid DNA	ChEMBL.	10340602
EC50 (functional)	> 50 uM	In vitro activity against topoisomerase-II mediated cleavage of supercoiled pBR322 plasmid DNA	ChEMBL.	10340602
EC50 (functional)	> 50 uM	In vitro activity against topoisomerase-II mediated cleavage of supercoiled pBR322 plasmid DNA	ChEMBL.	10340602
IC50 (functional)	= 0.044 uM	In vitro cytotoxicity (CTX) against murine leukemia cells (P388) using colorimeric tetrazolium-formazan method	ChEMBL.	10340602
IC50 (functional)	= 0.044 uM	In vitro cytotoxicity (CTX) against murine leukemia cells (P388) using colorimeric tetrazolium-formazan method	ChEMBL.	10340602
IC50 (functional)	= 0.54 uM	In vitro cytotoxicity (CTX) against human stomach cancer cells (MKN-45) using sulforhodamine B dye-staining method	ChEMBL.	10340602
IC50 (functional)	= 0.54 uM	In vitro cytotoxicity (CTX) against human stomach cancer cells (MKN-45) using sulforhodamine B dye-staining method	ChEMBL.	10340602
IC50 (functional)	= 0.92 uM	In vitro antitumor activity against human solid tumor ovarian cell line OVCAR-3	ChEMBL.	10021917
IC50 (functional)	= 0.92 uM	In vitro antitumor activity against human solid tumor ovarian cell line OVCAR-3	ChEMBL.	10021917
IC50 (functional)	= 2.3 uM	In vitro antitumor activity against human solid tumor prostrate cell line DU-145	ChEMBL.	10021917
IC50 (functional)	= 2.3 uM	In vitro antitumor activity against human solid tumor prostrate cell line DU-145	ChEMBL.	10021917
IC50 (binding)	= 3.8 uM	In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)	ChEMBL.	10340602
IC50 (binding)	= 3.8 uM	In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)	ChEMBL.	10340602
IC50 (functional)	> 10 uM	In vitro antitumor activity against human solid tumor colon cell line HT-29	ChEMBL.	10021917
IC50 (functional)	> 10 uM	In vitro antitumor activity against human solid tumor colon cell line HT-29	ChEMBL.	10021917
IC50 (binding)	= 13 uM	Concentration of the compound required to inhibit human DNA topoisomerase I (Topo I)	ChEMBL.	10021917
IC50 (binding)	= 13 uM	Concentration of the compound required to inhibit human DNA topoisomerase I (Topo I)	ChEMBL.	10021917
IC50 (binding)	= 90 uM	In vitro activity against Epidermal growth factor receptor (using poly(Glu4Tyr1) as a substrate)	ChEMBL.	10340602
IC50 (binding)	= 90 uM	In vitro activity against Epidermal growth factor receptor (using poly(Glu4Tyr1) as a substrate)	ChEMBL.	10340602

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Mus musculus	ChEMBL23	10340602
Homo sapiens	ChEMBL23	10021917

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL21108
PubChem: 21197160

Bibliographic References

2 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 24206