Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0014 | 0.0153 |
Trypanosoma brucei | unspecified product | 0.0018 | 0.0021 | 0.0267 |
Trypanosoma brucei | unspecified product | 0.0026 | 0.0055 | 0.0691 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0026 | 0.0055 | 0.0691 |
Mycobacterium ulcerans | hypothetical protein | 0.0109 | 0.0396 | 0.0384 |
Onchocerca volvulus | 0.0047 | 0.0142 | 0.3427 | |
Onchocerca volvulus | 0.0103 | 0.0373 | 1 | |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0026 | 0.0055 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0021 | 0.0267 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0037 | 0.0037 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0018 | 0.0021 | 0.1383 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0011 | 0.0011 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0026 | 0.0052 | 0.065 |
Echinococcus granulosus | lamin dm0 | 0.0047 | 0.0142 | 0.0312 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0016 | 0.0014 | 0.6765 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.0524 | 0.1151 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0098 | 0.035 | 0.4378 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0057 | 0.0181 | 0.1921 |
Onchocerca volvulus | 0.0022 | 0.0037 | 0.0461 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0029 | 0.0066 | 0.0827 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0016 | 0.0012 | 0.5 |
Trypanosoma brucei | metacaspase 5, putative | 0.0018 | 0.0021 | 0.0265 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0022 | 0.0037 | 0.0025 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0057 | 0.0181 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.0944 | 1 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0016 | 0.0012 | 0.0153 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0755 | 0.3068 | 0.6737 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.005 | 0.0153 | 0.0337 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0016 | 0.0012 | 0.5784 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0016 | 0.0012 | 0.0153 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1115 | 0.4554 | 1 |
Mycobacterium ulcerans | imidazoleglycerol-phosphate dehydratase | 0.2432 | 1 | 1 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0016 | 0.0012 | 0.5 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0022 | 0.0037 | 0.5847 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.005 | 0.0153 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0023 | 0.0041 | 0.0089 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0025 | 0.0051 | 0.0541 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Leishmania major | metacaspase, putative | 0.0018 | 0.0021 | 0.0265 |
Echinococcus granulosus | muscleblind protein | 0.0241 | 0.0944 | 0.2072 |
Echinococcus granulosus | caspase 2 | 0.0018 | 0.0021 | 0.0047 |
Schistosoma mansoni | DNA polymerase eta | 0.0044 | 0.0127 | 0.028 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0026 | 0.0055 | 0.0691 |
Brugia malayi | Isocitrate dehydrogenase | 0.0013 | 0.0000087966 | 0.0001 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0037 | 0.0397 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0026 | 0.0055 | 0.0043 |
Echinococcus granulosus | intermediate filament protein | 0.0047 | 0.0142 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0037 | 0.0397 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0018 | 0.0021 | 0.0047 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0022 | 0.0037 | 0.0467 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0078 | 0.0267 | 0.2831 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0373 | 0.3958 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0025 | 0.0051 | 0.0541 |
Giardia lamblia | DINP protein human, muc B family | 0.0026 | 0.0055 | 0.5 |
Echinococcus multilocularis | dna polymerase eta | 0.0044 | 0.0127 | 0.028 |
Brugia malayi | Cell death protein 3 precursor | 0.0018 | 0.0021 | 0.0225 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0022 | 0.0037 | 0.0051 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0078 | 0.0267 | 0.0587 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0026 | 0.0055 | 0.0122 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0018 | 0.0021 | 0.0047 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.005 | 0.0153 | 0.0153 |
Echinococcus granulosus | caspase | 0.0018 | 0.0021 | 0.0047 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0047 | 0.0142 | 0.1505 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0029 | 0.0066 | 0.0827 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.0524 | 0.1151 |
Echinococcus multilocularis | muscleblind protein | 0.0241 | 0.0944 | 0.2072 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.005 | 0.0153 | 0.0141 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0022 | 0.0037 | 0.0025 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0029 | 0.0066 | 0.0827 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0041 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0181 | 0.1921 |
Echinococcus multilocularis | geminin | 0.014 | 0.0524 | 0.1151 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0037 | 0.0025 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0037 | 0.0393 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0011 | 0.0011 |
Trypanosoma cruzi | metacaspase, putative | 0.0018 | 0.0021 | 0.0265 |
Echinococcus multilocularis | lamin | 0.0047 | 0.0142 | 0.0312 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0026 | 0.0052 | 0.3397 |
Trypanosoma brucei | Metacaspase-4 | 0.0018 | 0.0021 | 0.0265 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0016 | 0.0014 | 0.0002 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0021 | 0.0267 |
Trypanosoma brucei | metacaspase MCA2 | 0.0018 | 0.0021 | 0.0265 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0016 | 0.0012 | 0.5784 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0037 | 0.0397 |
Onchocerca volvulus | 0.0057 | 0.0181 | 0.4544 | |
Plasmodium falciparum | acyl-CoA synthetase | 0.0016 | 0.0014 | 0.6765 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0018 | 0.0021 | 0.0265 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0011 | 0.0011 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0207 | 0.08 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0022 | 0.0037 | 0.5847 |
Echinococcus multilocularis | caspase 8 | 0.0018 | 0.0021 | 0.0047 |
Plasmodium vivax | hypothetical protein, conserved | 0.0018 | 0.0021 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0041 | 0.0116 | 0.1231 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0037 | 0.0025 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Onchocerca volvulus | 0.0047 | 0.0142 | 0.3427 | |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0016 | 0.0012 | 0.0012 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0016 | 0.0014 | 0.0014 |
Trypanosoma cruzi | metacaspase, putative | 0.0018 | 0.0021 | 0.0265 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0037 | 0.0397 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0109 | 0.0396 | 0.0396 |
Schistosoma mansoni | lamin | 0.0047 | 0.0142 | 0.0312 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0018 | 0.0021 | 0.1383 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0022 | 0.0037 | 0.0467 |
Echinococcus multilocularis | musashi | 0.0047 | 0.0142 | 0.0312 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0098 | 0.035 | 0.4378 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0037 | 0.0397 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0057 | 0.0181 | 0.0398 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0044 | 0.0127 | 0.1591 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0044 | 0.0127 | 0.1591 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0098 | 0.035 | 0.4378 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.005 | 0.0153 | 0.1914 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0037 | 0.0393 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0207 | 0.08 | 1 |
Brugia malayi | intermediate filament protein | 0.0047 | 0.0142 | 0.1505 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0142 | 0.1505 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0018 | 0.0021 | 0.0047 |
Trypanosoma brucei | metacaspase | 0.0018 | 0.0021 | 0.0265 |
Echinococcus granulosus | geminin | 0.014 | 0.0524 | 0.1151 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0026 | 0.0055 | 0.0691 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0022 | 0.0037 | 0.0467 |
Trypanosoma brucei | metacaspase MCA3 | 0.0018 | 0.0021 | 0.0265 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0018 | 0.0021 | 0.0047 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0018 | 0.0021 | 0.1383 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0022 | 0.0037 | 0.0025 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0026 | 0.0055 | 0.0691 |
Echinococcus granulosus | lamin | 0.0047 | 0.0142 | 0.0312 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0018 | 0.0021 | 0.0225 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0041 | 0.0116 | 0.1231 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0018 | 0.0021 | 0.0047 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0026 | 0.0055 | 0.0055 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0026 | 0.0055 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0026 | 0.0055 | 0.0587 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0023 | 0.0041 | 0.0089 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0026 | 0.0055 | 0.0122 |
Brugia malayi | hypothetical protein | 0.0103 | 0.0373 | 0.3958 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0116 | 0.1231 |
Mycobacterium leprae | Probable imidazole glycerol-phosphate dehydratase HisB | 0.12 | 0.4904 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.005 | 0.0153 | 0.0141 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0018 | 0.0021 | 0.0047 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0026 | 0.0055 | 0.0043 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0016 | 0.0014 | 1 |
Plasmodium falciparum | metacaspase 1 | 0.0018 | 0.0021 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0044 | 0.0127 | 0.1591 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0127 | 0.135 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0078 | 0.0267 | 0.0587 |
Echinococcus granulosus | dna polymerase eta | 0.0044 | 0.0127 | 0.028 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0044 | 0.0127 | 0.135 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0138 | 0.1467 |
Leishmania major | DNA polymerase eta, putative | 0.0026 | 0.0052 | 0.065 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0241 | 0.0944 | 0.2072 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.005 | 0.0153 | 0.0141 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0078 | 0.0267 | 0.0587 |
Plasmodium vivax | metacaspase 1, putative | 0.0018 | 0.0021 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0207 | 0.08 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0014 | 0.0153 |
Trypanosoma cruzi | metacaspase, putative | 0.0018 | 0.0021 | 0.0265 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0029 | 0.0066 | 0.0827 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0037 | 0.0025 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0018 | 0.0021 | 0.0265 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.005 | 0.0153 | 0.0337 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0026 | 0.0055 | 0.0122 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0021 | 0.0267 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0013 | 0.0000087966 | 0.0001 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Leishmania major | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0057 | 0.0181 | 0.0398 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0035 | 0.0093 | 0.1156 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.0944 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0033 | 0.0084 | 0.5475 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.005 | 0.0153 | 0.0337 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0037 | 0.0397 |
Schistosoma mansoni | lamin | 0.0047 | 0.0142 | 0.0312 |
Brugia malayi | Muscleblind-like protein | 0.0241 | 0.0944 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0078 | 0.0267 | 0.0587 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0026 | 0.0055 | 0.0055 |
Schistosoma mansoni | intermediate filament proteins | 0.0047 | 0.0142 | 0.0312 |
Echinococcus multilocularis | lamin dm0 | 0.0047 | 0.0142 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0014 | 0.0153 |
Echinococcus multilocularis | dna polymerase kappa | 0.0026 | 0.0055 | 0.0122 |
Echinococcus multilocularis | caspase 2 | 0.0018 | 0.0021 | 0.0047 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0026 | 0.0055 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0062 | 0.0661 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0022 | 0.0037 | 0.0025 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0062 | 0.0137 |
Plasmodium falciparum | metacaspase-like protein | 0.0018 | 0.0021 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0021 | 0.0225 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0022 | 0.0037 | 0.0051 |
Loa Loa (eye worm) | intermediate filament protein | 0.0047 | 0.0142 | 0.1505 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0078 | 0.0267 | 0.0587 |
Trypanosoma brucei | unspecified product | 0.0018 | 0.0021 | 0.0267 |
Echinococcus granulosus | dna polymerase kappa | 0.0026 | 0.0055 | 0.0122 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0026 | 0.0055 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0014 | 0.0153 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0022 | 0.0037 | 0.5847 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0028 | 0.0062 | 0.0661 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0016 | 0.0012 | 0.08 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0021 | 0.0225 |
Trypanosoma cruzi | metacaspase, putative | 0.0018 | 0.0021 | 0.0265 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0026 | 0.0055 | 0.0691 |
Echinococcus granulosus | caspase 8 | 0.0018 | 0.0021 | 0.0047 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0016 | 0.0012 | 0.08 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1115 | 0.4554 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0041 | 0.0116 | 0.1231 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0078 | 0.0267 | 0.2831 |
Mycobacterium ulcerans | hypothetical protein | 0.0022 | 0.0037 | 0.0025 |
Echinococcus multilocularis | caspase | 0.0018 | 0.0021 | 0.0047 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0026 | 0.0055 | 0.0587 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0207 | 0.08 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0047 | 0.0142 | 0.1505 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0022 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0014 | 0.0153 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1115 | 0.4554 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0078 | 0.0267 | 0.0587 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0011 | 0.0011 |
Brugia malayi | isocitrate dehydrogenase | 0.0013 | 0.0000087966 | 0.0001 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0078 | 0.0267 | 0.0587 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.005 | 0.0153 | 0.0337 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 500 mg kg-1 | Ability to reinduce anesthesia in mice as a measure of in vivo sedative-hypnotic activity | ChEMBL. | 7241505 |
ED50 (functional) | = 500 mg kg-1 | Ability to reinduce anesthesia in mice as a measure of in vivo sedative-hypnotic activity | ChEMBL. | 7241505 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.