Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin b | 0.0662 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.017 | 0.1455 | 0.1287 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0132 | 0.0791 | 0.0791 |
Leishmania major | cysteine peptidase A (CPA) | 0.0313 | 0.3939 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0091 | 0.0082 | 0.008 |
Echinococcus granulosus | cathepsin b | 0.0662 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.0132 | 0.0791 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0216 | 0.2246 | 0.2093 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.0132 | 0.0791 | 0.2009 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Onchocerca volvulus | Cathepsin F homolog | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.017 | 0.1455 | 0.1287 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Plasmodium vivax | vivapain-2 | 0.0313 | 0.3939 | 1 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0216 | 0.2246 | 0.5699 |
Loa Loa (eye worm) | cathepsin B | 0.0255 | 0.2928 | 0.2927 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Plasmodium vivax | unspecified product | 0.017 | 0.1455 | 0.3369 |
Plasmodium vivax | vivapain-1 | 0.017 | 0.1455 | 0.3369 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0662 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.017 | 0.1455 | 0.3695 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0662 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.017 | 0.1455 | 0.2109 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.017 | 0.1455 | 0.2109 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0216 | 0.2246 | 0.5699 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.017 | 0.1455 | 0.1287 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0313 | 0.3939 | 0.382 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0193 | 0.0192 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.017 | 0.1455 | 0.1455 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0255 | 0.2928 | 0.2928 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0216 | 0.2246 | 0.462 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.2246 | 0.2245 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.1597 |
Echinococcus granulosus | cathepsin l1 | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0098 | 0.0193 | 0.0193 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0313 | 0.3939 | 1 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Echinococcus granulosus | cathepsin l1 | 0.0216 | 0.2246 | 0.2245 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0313 | 0.3939 | 0.3938 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Loa Loa (eye worm) | fibroinase | 0.0313 | 0.3939 | 0.3938 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0193 | 0.0192 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0193 | 0.0192 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0313 | 0.3939 | 0.3938 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.017 | 0.1455 | 0.3693 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0313 | 0.3939 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.2246 | 0.2245 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0313 | 0.3939 | 0.3938 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.0132 | 0.0791 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0255 | 0.2928 | 0.2789 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.0132 | 0.0791 | 0.2703 |
Brugia malayi | Cathepsin L-like precursor | 0.0216 | 0.2246 | 0.2093 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.017 | 0.1455 | 0.3693 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0313 | 0.3939 | 0.382 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0255 | 0.2928 | 0.7433 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.3939 | 0.3938 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0313 | 0.3939 | 0.3938 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Echinococcus granulosus | cathepsin L | 0.017 | 0.1455 | 0.1454 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0662 | 1 | 1 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0216 | 0.2246 | 0.2246 |
Echinococcus multilocularis | cathepsin L | 0.017 | 0.1455 | 0.1454 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0132 | 0.0791 | 0.061 |
Echinococcus granulosus | cathepsin b | 0.0662 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Echinococcus multilocularis | cathepsin b | 0.0662 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0662 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.017 | 0.1455 | 0.1287 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0255 | 0.2928 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.017 | 0.1455 | 0.1287 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Loa Loa (eye worm) | cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Giardia lamblia | Cathepsin B precursor | 0.0255 | 0.2928 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0091 | 0.0082 | 0.008 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.017 | 0.1455 | 0.1455 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0132 | 0.0791 | 0.0791 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0313 | 0.3939 | 0.3938 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0098 | 0.0193 | 0.0193 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0662 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0255 | 0.2928 | 0.7434 |
Echinococcus granulosus | cysteine protease | 0.017 | 0.1455 | 0.1454 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0313 | 0.3939 | 0.382 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.0132 | 0.0791 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0132 | 0.0791 | 0.0791 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.0132 | 0.0791 | 0.5 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.017 | 0.1455 | 0.1455 |
Onchocerca volvulus | Cathepsin L homolog | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.2246 | 0.2245 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0255 | 0.2928 | 0.7434 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.017 | 0.1455 | 0.3695 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0216 | 0.2246 | 0.2093 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.017 | 0.1455 | 0.2109 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Toxoplasma gondii | cathepsin B | 0.0255 | 0.2928 | 0.6788 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.017 | 0.1455 | 0.1455 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.017 | 0.1455 | 0.1455 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Plasmodium vivax | vivapain-2 | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0216 | 0.2246 | 0.2093 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0216 | 0.2246 | 0.2093 |
Echinococcus multilocularis | cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Giardia lamblia | Cathepsin B precursor | 0.0255 | 0.2928 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0313 | 0.3939 | 0.3939 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0313 | 0.3939 | 0.3938 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0098 | 0.0193 | 0.0192 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.017 | 0.1455 | 0.1454 |
Loa Loa (eye worm) | hypothetical protein | 0.0662 | 1 | 1 |
Plasmodium vivax | vivapain-3 | 0.017 | 0.1455 | 0.3369 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Cures (functional) | = 0 | Number of survivors of the total treated mice with B-16 melanoma, at 60 days. | ChEMBL. | 6806475 |
ILS (functional) | = 72 % | Percent increase in median life span of BDF1 mice with P-388 leukemia at dose 12.5 mg/kg administered intraperitoneally | ChEMBL. | 6806475 |
ILS (functional) | = 100 % | Percent increase in median life span of BDF1 mice with B-16 melanoma at dose 12.5 mg/kg administered intraperitoneally | ChEMBL. | 6806475 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.