Detailed information for compound 325815

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 202.04 | Formula: C6H7AsO3
  • H donors: 2 H acceptors: 2 LogP: 0.93 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[As](Oc1ccccc1)O
  • InChi: 1S/C6H7AsO3/c8-7(9)10-6-4-2-1-3-5-6/h1-5,8-9H
  • InChiKey: NOJGJOHOYAWLBB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens carbonic anhydrase VA, mitochondrial Starlite/ChEMBL References
Homo sapiens carbonic anhydrase VB, mitochondrial References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania major carbonic anhydrase-like protein carbonic anhydrase VA, mitochondrial 305 aa 255 aa 25.9 %
Trypanosoma brucei carbonic anhydrase-like protein carbonic anhydrase VB, mitochondrial 317 aa 287 aa 24.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus rhodopsin orphan GPCR 0.0127 0.0728 0.2204
Onchocerca volvulus 0.0127 0.0728 0.1935
Brugia malayi Tachykinin-like peptides receptor 99D 0.0127 0.0728 0.1043
Onchocerca volvulus Neuropeptide F receptor homolog 0.0127 0.0728 0.1935
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0127 0.0728 0.1996
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0042 0.0195 0.3021
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Echinococcus granulosus neuropeptides capa receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis g protein coupled receptor 0.0127 0.0728 0.0728
Brugia malayi putative neuropeptide receptor NPR1 0.0127 0.0728 0.1043
Loa Loa (eye worm) hypothetical protein 0.0067 0.0352 0.0827
Schistosoma mansoni amine oxidase 0.004 0.0184 0.0557
Echinococcus granulosus g protein coupled receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0132 0.0132
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0162 0.1587
Entamoeba histolytica glycogen phosphorylase, putative 0.0537 0.3303 1
Loa Loa (eye worm) hypothetical protein 0.0248 0.1487 0.4355
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0127 0.0728 0.2204
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0278 0.5316
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0161 0.2827
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0067 0.0352 0.048
Schistosoma mansoni opsin-like receptor 0.0127 0.0728 0.2204
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0132 0.1273
Echinococcus granulosus short transient receptor potential channel 6 0.0129 0.0743 0.2249
Brugia malayi hypothetical protein 0.0127 0.0728 0.1043
Loa Loa (eye worm) G-protein coupled receptor 0.0127 0.0728 0.1996
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0067 0.0352 1
Brugia malayi hypothetical protein 0.0127 0.0728 0.1043
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0232 0.1388 0.3937
Brugia malayi larval opioid receptor 0.0127 0.0728 0.1043
Entamoeba histolytica glycogen phosphorylase, putative 0.0232 0.1388 0.3914
Schistosoma mansoni transient receptor potential channel 0.0129 0.0743 0.2249
Echinococcus granulosus tm gpcr rhodopsin 0.0127 0.0728 0.2204
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0805 0.2436
Echinococcus granulosus serotonin receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis glycogen phosphorylase 0.0537 0.3303 0.3303
Echinococcus multilocularis neuropeptides capa receptor 0.0127 0.0728 0.0728
Echinococcus multilocularis G-protein coupled receptor, putative 0.0127 0.0728 0.0728
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0132 0.0132
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0162 0.2119
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0082 0.0448 1
Echinococcus granulosus dnaJ subfamily B 0.0408 0.249 0.7539
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0132 0.0399
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0574 0.3533 1
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0082 0.0448 0.1355
Schistosoma mansoni opsin-like receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Brugia malayi Serotonin receptor 0.1081 0.6718 1
Echinococcus multilocularis neuropeptide receptor 0.0127 0.0728 0.0728
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0184 0.0074
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0127 0.0728 0.1043
Schistosoma mansoni neuropeptide receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0127 0.0728 0.0728
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.0269 0.4744
Loa Loa (eye worm) hypothetical protein 0.0037 0.0161 0.0234
Echinococcus multilocularis rhodopsin orphan GPCR 0.0127 0.0728 0.0728
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0127 0.0728 0.2204
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0082 0.0448 0.0845
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0161 0.1543
Echinococcus multilocularis neuropeptide s receptor 0.0127 0.0728 0.0728
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0127 0.0728 0.1043
Schistosoma mansoni neuropeptide F-like receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.0037 0.0161 0.0234
Echinococcus granulosus alpha 1A adrenergic receptor 0.0127 0.0728 0.2204
Onchocerca volvulus 0.0037 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0073 0.0387 0.0937
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0127 0.0728 0.1043
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0121 0.0365
Brugia malayi AKH receptor 0.0127 0.0728 0.1043
Echinococcus multilocularis serotonin receptor 0.0248 0.1487 0.1487
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0533 0.3279 1
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0162 0.0005
Brugia malayi hypothetical protein 0.0127 0.0728 0.1043
Onchocerca volvulus 0.0127 0.0728 0.1935
Onchocerca volvulus 0.0127 0.0728 0.1935
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0127 0.0728 0.2204
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0067 0.0352 0.1065
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0127 0.0728 0.0728
Echinococcus granulosus lysine specific histone demethylase 1A 0.004 0.0184 0.0557
Schistosoma mansoni hypothetical protein 0.0127 0.0728 0.2204
Brugia malayi Pre-SET motif family protein 0.0032 0.0132 0.0151
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0127 0.0728 0.2204
Brugia malayi hypothetical protein 0.0127 0.0728 0.1043
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0127 0.0728 0.2204
Onchocerca volvulus 0.0127 0.0728 0.1935
Echinococcus granulosus carbonic anhydrase 0.0067 0.0352 0.1065
Echinococcus granulosus rhodopsin orphan GPCR 0.0127 0.0728 0.2204
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0067 0.0352 0.048
Loa Loa (eye worm) hypothetical protein 0.004 0.0184 0.0306
Schistosoma mansoni transient receptor potential channel 0.0196 0.1159 0.3509
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.0269 0.0816
Schistosoma mansoni myosin xvIII 0.0127 0.0728 0.2204
Schistosoma mansoni biogenic amine receptor 0.0127 0.0728 0.2204
Brugia malayi Melatonin receptor type 1A 0.0127 0.0728 0.1043
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0067 0.0352 0.0827
Loa Loa (eye worm) hypothetical protein 0.0037 0.0161 0.0234
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0805 0.2436
Brugia malayi sulfakinin receptor protein 0.0127 0.0728 0.1043
Echinococcus multilocularis glycogen phosphorylase 0.0537 0.3303 0.3303
Echinococcus multilocularis carbonic anhydrase 0.0067 0.0352 0.0352
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0319 0.0965
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Loa Loa (eye worm) hypothetical protein 0.0123 0.0702 0.1916
Schistosoma mansoni peptidase Clp (S14 family) 0.0082 0.0448 0.1355
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.004 0.0184 0.2719
Echinococcus multilocularis rhodopsin orphan GPCR 0.0127 0.0728 0.0728
Schistosoma mansoni amine GPCR 0.029 0.1748 0.5293
Echinococcus multilocularis GPCR, family 2 0.0047 0.0224 0.0224
Entamoeba histolytica glycogen phosphorylase, putative 0.0537 0.3303 1
Schistosoma mansoni hypothetical protein 0.0127 0.0728 0.2204
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0127 0.0728 0.0728
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0127 0.0728 0.0728
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0805 0.2436
Loa Loa (eye worm) hypothetical protein 0.0066 0.0346 0.081
Echinococcus granulosus tm gpcr rhodopsin 0.0127 0.0728 0.2204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0127 0.0728 0.2204
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0082 0.0448 1
Onchocerca volvulus 0.0127 0.0728 0.1935
Loa Loa (eye worm) neuropeptide F receptor 0.0127 0.0728 0.1996
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0082 0.0448 0.085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0127 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0073 0.0387 0.0387
Brugia malayi hypothetical protein 0.0127 0.0728 0.1043
Onchocerca volvulus 0.0127 0.0728 0.1935
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0082 0.0448 0.085
Schistosoma mansoni amine GPCR 0.0127 0.0728 0.2204
Loa Loa (eye worm) glycogen phosphorylase 0.0537 0.3303 1
Schistosoma mansoni hypothetical protein 0.0047 0.0224 0.0677
Loa Loa (eye worm) neuropeptide F receptor 0.0127 0.0728 0.1996
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Onchocerca volvulus 0.0127 0.0728 0.1935
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0127 0.0728 0.2204
Onchocerca volvulus Glycogen phosphorylase homolog 0.0537 0.3303 1
Plasmodium falciparum carbonic anhydrase 0.0067 0.0352 0.7352
Onchocerca volvulus 0.0127 0.0728 0.1935
Schistosoma mansoni amine GPCR 0.0127 0.0728 0.2204
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0162 0.2883
Loa Loa (eye worm) hypothetical protein 0.0082 0.0448 0.1125
Brugia malayi neuropeptide F receptor 0.0127 0.0728 0.1043
Schistosoma mansoni carbonic anhydrase-related 0.0067 0.0352 0.1065
Brugia malayi RE15519p 0.0127 0.0728 0.1043
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.0269 0.0348
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0082 0.0448 1
Brugia malayi ORL1-like opioid receptor 0.0127 0.0728 0.1043
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0161 0.0234
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0162 0.0016
Leishmania major carbonic anhydrase-like protein 0.0067 0.0352 1
Echinococcus granulosus g-protein coupled receptor 0.0127 0.0728 0.2204
Echinococcus granulosus TRP transient receptor potential channel 0.0073 0.0387 0.1172
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0162 0.0197
Leishmania major hypothetical protein, conserved 0.0037 0.0161 0.2827
Echinococcus multilocularis lysine specific histone demethylase 1A 0.004 0.0184 0.0184
Toxoplasma gondii histone lysine-specific demethylase 0.004 0.0184 0.2719
Brugia malayi hypothetical protein 0.0127 0.0728 0.1043
Echinococcus multilocularis carbonic anhydrase 0.0067 0.0352 0.0352
Echinococcus granulosus orexin receptor type 2 0.0127 0.0728 0.2204
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0161 0.0161
Echinococcus granulosus rhodopsin orphan GPCR 0.0127 0.0728 0.2204
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0127 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0161 0.0487
Brugia malayi hypothetical protein 0.0127 0.0728 0.1043
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0082 0.0448 1
Brugia malayi beta-lactamase family protein 0.0037 0.0161 0.0195
Brugia malayi Pre-SET motif family protein 0.022 0.1311 0.1915
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0157 0.0476
Echinococcus granulosus carbonic anhydrase 0.0067 0.0352 0.1065
Onchocerca volvulus 0.0127 0.0728 0.1935
Schistosoma mansoni histamine h1 receptor 0.0127 0.0728 0.2204
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.004 0.0184 0.0557
Loa Loa (eye worm) hypothetical protein 0.0037 0.0161 0.0234
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0161 0.2079
Echinococcus granulosus neuropeptide receptor 0.0127 0.0728 0.2204
Schistosoma mansoni biogenic amine receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0127 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0127 0.0728 0.2204
Echinococcus multilocularis 0.004 0.0184 0.0184
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0067 0.0352 0.048
Echinococcus granulosus fmrfamide receptor 0.0127 0.0728 0.2204
Echinococcus granulosus tar DNA binding protein 0.0062 0.0321 0.0971
Echinococcus granulosus neuropeptide s receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.022 0.1311 0.3809
Echinococcus multilocularis dnaJ subfamily B 0.0408 0.249 0.249
Schistosoma mansoni biogenic amine (5HT) receptor 0.0127 0.0728 0.2204
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.004 0.0184 0.2719
Plasmodium vivax hypothetical protein, conserved 0.004 0.0184 0.2719
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0574 0.3533 1
Echinococcus multilocularis fmrfamide receptor 0.0127 0.0728 0.0728
Echinococcus multilocularis carbonic anhydrase II 0.0067 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0101 0.0564 0.1487
Echinococcus granulosus geminin 0.0502 0.3081 0.9329
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0232 0.1388 0.364
Echinococcus granulosus allatostatin A receptor 0.0127 0.0728 0.2204
Brugia malayi hypothetical protein 0.004 0.0184 0.0229
Chlamydia trachomatis glycogen phosphorylase 0.0537 0.3303 1
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni neuropeptide receptor 0.0127 0.0728 0.2204
Brugia malayi GnHR receptor homolog 0.0127 0.0728 0.1043
Echinococcus granulosus neuropeptide receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0805 0.0805
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0224 0.0677
Toxoplasma gondii hypothetical protein 0.0067 0.0352 0.7352
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0082 0.0448 0.0448
Schistosoma mansoni carbonic anhydrase-related 0.0067 0.0352 0.1065
Echinococcus multilocularis sex peptide receptor 0.0127 0.0728 0.0728
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0067 0.0352 0.1065
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0321 0.0434
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.004 0.0184 0.2226
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Brugia malayi Dopamine receptor protein 2 0.0127 0.0728 0.1043
Toxoplasma gondii ABC1 family protein 0.0037 0.0161 0.2079
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0067 0.0352 0.048
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0224 0.0289
Toxoplasma gondii hypothetical protein 0.0028 0.0109 0.0633
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Onchocerca volvulus 0.0127 0.0728 0.1935
Echinococcus multilocularis rhodopsin orphan GPCR 0.0127 0.0728 0.0728
Echinococcus multilocularis neuropeptide receptor A26 0.0127 0.0728 0.0728
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis neuropeptide receptor 0.0127 0.0728 0.0728
Echinococcus multilocularis dro:myosuppressin receptor 0.0127 0.0728 0.0728
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0161 0.2827
Echinococcus multilocularis rhodopsin orphan GPCR 0.0127 0.0728 0.0728
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0127 0.0728 0.2204
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0161 0.0487
Loa Loa (eye worm) hypothetical protein 0.0037 0.0161 0.0234
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0161 0.2827
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.0196 0.1159 0.3336
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0127 0.0728 0.1043
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0127 0.0728 0.2204
Schistosoma mansoni hypothetical protein 0.0047 0.0224 0.0677
Echinococcus granulosus neuropeptide Y receptor 0.0127 0.0728 0.2204
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0162 0.2119
Loa Loa (eye worm) hypothetical protein 0.0067 0.0352 0.0827
Schistosoma mansoni hypothetical protein 0.0127 0.0728 0.2204
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0224 0.0429
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Brugia malayi hypothetical protein 0.0127 0.0728 0.1043
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0127 0.0728 0.2204
Schistosoma mansoni growth hormone secretagogue receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.004 0.0184 0.0306
Loa Loa (eye worm) hypothetical protein 0.0248 0.1487 0.4355
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0132 0.0399
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0157 0.0476
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0082 0.0448 0.0845
Plasmodium falciparum protoporphyrinogen oxidase 0.004 0.0184 0.2719
Echinococcus multilocularis orexin receptor type 2 0.0127 0.0728 0.0728
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0082 0.0448 1
Trypanosoma brucei carbonic anhydrase-like protein 0.0067 0.0352 1
Trypanosoma cruzi UDP-galactopyranose mutase 0.004 0.0184 0.3698
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0082 0.0448 1
Toxoplasma gondii exonuclease III APE 0.0037 0.0162 0.2119
Echinococcus multilocularis neuropeptide Y receptor 0.0127 0.0728 0.0728
Loa Loa (eye worm) carbonic anhydrase 3 0.0067 0.0352 0.0827
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0162 0.0005
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Brugia malayi hypothetical protein 0.0036 0.0157 0.0189
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.011 0.0076
Brugia malayi follicle stimulating hormone receptor 0.0127 0.0728 0.1043
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.0269 0.0348
Entamoeba histolytica glycogenphosphorylase, putative 0.0232 0.1388 0.3914
Echinococcus granulosus G protein coupled receptor 139 0.0127 0.0728 0.2204
Echinococcus multilocularis short transient receptor potential channel 6 0.0129 0.0743 0.0743
Schistosoma mansoni ap endonuclease 0.0037 0.0162 0.0492
Schistosoma mansoni hypothetical protein 0.0036 0.0157 0.0476
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.0857 0.2399
Onchocerca volvulus 0.004 0.0184 0.0232
Brugia malayi Dopamine receptor protein 1 0.0127 0.0728 0.1043
Echinococcus granulosus hypothetical protein 0.0127 0.0728 0.2204
Echinococcus granulosus carbonic anhydrase 0.0067 0.0352 0.1065
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0127 0.0728 0.1996
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0127 0.0728 0.2204
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis carbonic anhydrase 0.0067 0.0352 0.0352
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0109 0.0633
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0127 0.0728 0.2204
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0162 0.0492
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Trichomonas vaginalis set domain proteins, putative 0.025 0.1501 0.4266
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni glycogen phosphorylase 0.0232 0.1388 0.4204
Echinococcus granulosus transient receptor potential ion channel A 0.0189 0.1118 0.3385
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0127 0.0728 0.0728
Brugia malayi hypothetical protein 0.0127 0.0728 0.1043
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0127 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Leishmania major UDP-galactopyranose mutase 0.004 0.0184 0.3698
Onchocerca volvulus 0.0037 0.0161 0.0159
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0127 0.0728 0.0728
Echinococcus granulosus neuropeptides capa receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) RNA binding protein 0.0062 0.0321 0.073
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0127 0.0728 0.1996
Loa Loa (eye worm) hypothetical protein 0.004 0.0184 0.0306
Loa Loa (eye worm) hypothetical protein 0.0148 0.0857 0.2399
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0109 0.0633
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0321 0.073
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0162 0.2883
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0127 0.0728 0.2204
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0321 0.0971
Schistosoma mansoni ap endonuclease 0.0037 0.0162 0.0492
Onchocerca volvulus 0.0127 0.0728 0.1935
Echinococcus granulosus 7TM GPCR rhodopsin 0.0127 0.0728 0.2204
Echinococcus multilocularis g protein coupled receptor 0.0127 0.0728 0.0728
Brugia malayi neuropeptide F receptor 0.0127 0.0728 0.1043
Echinococcus granulosus GPCR family 2 0.0047 0.0224 0.0677
Mycobacterium ulcerans dehydrogenase 0.004 0.0184 0.0069
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0157 0.0157
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0127 0.0728 0.0728
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0132 0.0399
Trichomonas vaginalis glycogen phosphorylase, putative 0.0537 0.3303 1
Schistosoma mansoni carbonic anhydrase-related 0.0067 0.0352 0.1065
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0139 0.0805 0.2235
Echinococcus granulosus somatostatin receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.0032 0.0132 0.0143
Onchocerca volvulus 0.0127 0.0728 0.1935
Echinococcus multilocularis fmrfamide receptor 0.0127 0.0728 0.0728
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0162 0.0238
Echinococcus granulosus tachykinin peptides receptor 99D 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0805 0.2436
Echinococcus multilocularis neuropeptide FF receptor 2 0.0127 0.0728 0.0728
Echinococcus granulosus dro:myosuppressin receptor 0.0127 0.0728 0.2204
Brugia malayi Serotonin receptor 0.0127 0.0728 0.1043
Schistosoma mansoni Lysine-specific histone demethylase 1 0.004 0.0184 0.0557
Echinococcus multilocularis transient receptor potential gamma protein 0.0196 0.1159 0.1159
Schistosoma mansoni amine oxidase 0.004 0.0184 0.0557
Brugia malayi carbohydrate phosphorylase 0.0537 0.3303 0.4893
Plasmodium vivax SET domain protein, putative 0.0032 0.0132 0.1273
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0224 0.0224
Schistosoma mansoni biogenic amine (5HT) receptor 0.0248 0.1487 0.4501
Brugia malayi G protein-coupled receptor F59B2.13 0.0127 0.0728 0.1043
Echinococcus multilocularis somatostatin receptor 0.0127 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni glycogen phosphorylase 0.0537 0.3303 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0127 0.0728 0.1996
Echinococcus multilocularis cpg binding protein 0.003 0.012 0.012
Echinococcus granulosus transient receptor potential gamma protein 0.0196 0.1159 0.3509
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Mycobacterium ulcerans oxidoreductase 0.004 0.0184 0.0069
Brugia malayi RNA binding protein 0.0062 0.0321 0.0434
Echinococcus multilocularis rhodopsin orphan GPCR 0.0127 0.0728 0.0728
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0132 0.0399
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0127 0.0728 0.2204
Schistosoma mansoni neuropeptide receptor 0.0127 0.0728 0.2204
Schistosoma mansoni transient receptor potential channel 0.0129 0.0743 0.2249
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni hypothetical protein 0.0101 0.0564 0.1708
Onchocerca volvulus 0.0127 0.0728 0.1935
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0127 0.0728 0.1996
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Trichomonas vaginalis glycogen phosphorylase, putative 0.0537 0.3303 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0127 0.0728 0.0728
Schistosoma mansoni alpha-1 adrenergic receptor 0.0127 0.0728 0.2204
Brugia malayi SWIRM domain containing protein 0.004 0.0184 0.0229
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0127 0.0728 0.0728
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0127 0.0728 0.2204
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0162 0.0162
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0127 0.0728 0.2204
Mycobacterium ulcerans protoporphyrinogen oxidase 0.004 0.0184 0.0069
Loa Loa (eye worm) hypothetical protein 0.004 0.0184 0.0306
Brugia malayi Probable ClpP-like protease 0.0082 0.0448 0.0624
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.0857 0.1236
Echinococcus multilocularis neuropeptide Y receptor 0.0127 0.0728 0.0728
Echinococcus granulosus biogenic amine 5HT receptor 0.0127 0.0728 0.2204
Brugia malayi Transient-receptor-potential like protein 0.0073 0.0387 0.0533
Onchocerca volvulus 0.0032 0.0132 0.0068
Onchocerca volvulus 0.0127 0.0728 0.1935
Brugia malayi CXXC zinc finger family protein 0.0029 0.011 0.0119
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0805 0.0805
Echinococcus multilocularis g protein coupled receptor 0.0127 0.0728 0.0728
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0127 0.0728 0.2204
Echinococcus multilocularis geminin 0.0502 0.3081 0.3081
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0132 0.0399
Brugia malayi G-protein coupled receptor 0.0127 0.0728 0.1043
Schistosoma mansoni glycogen phosphorylase 0.0537 0.3303 1
Loa Loa (eye worm) beta-lactamase 0.0037 0.0161 0.0234
Echinococcus granulosus carbonic anhydrase II 0.0067 0.0352 0.1065
Schistosoma mansoni neuropeptide f receptor 76f 0.0127 0.0728 0.2204
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0805 0.2436
Schistosoma mansoni amine GPCR 0.0127 0.0728 0.2204
Schistosoma mansoni hypothetical protein 0.0127 0.0728 0.2204
Echinococcus multilocularis neuropeptides capa receptor 0.0127 0.0728 0.0728
Echinococcus granulosus peptide allatostatin:somatostatin 0.0127 0.0728 0.2204
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0067 0.0352 0.048
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0162 0.0004
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0162 0.0005
Brugia malayi hypothetical protein 0.0127 0.0728 0.1043
Schistosoma mansoni carbonic anhydrase 0.0067 0.0352 0.1065
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0067 0.0352 1
Brugia malayi beta-lactamase 0.0037 0.0161 0.0195
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Echinococcus multilocularis transient receptor potential ion channel A 0.0189 0.1118 0.1118
Echinococcus granulosus lysine specific histone demethylase 1A 0.004 0.0184 0.0557
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0224 0.0677
Schistosoma mansoni amine GPCR 0.0127 0.0728 0.2204
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.0857 0.1236
Onchocerca volvulus 0.025 0.1501 0.4357
Echinococcus multilocularis short transient receptor potential channel 6 0.0129 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.004 0.0184 0.2719
Schistosoma mansoni hypothetical protein 0.0047 0.0224 0.0677
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0127 0.0728 0.2204
Echinococcus granulosus biogenic amine 5HT receptor 0.0248 0.1487 0.4501
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0321 0.073
Schistosoma mansoni hypothetical protein 0.0408 0.249 0.7539
Echinococcus granulosus tm gpcr rhodopsin 0.0127 0.0728 0.2204
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0162 0.2883
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0321 0.0971
Onchocerca volvulus 0.0127 0.0728 0.1935
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Echinococcus granulosus rhodopsin orphan GPCR 0.0127 0.0728 0.2204
Echinococcus granulosus g protein coupled receptor 0.0127 0.0728 0.2204
Echinococcus granulosus sex peptide receptor 0.0127 0.0728 0.2204
Brugia malayi beta-lactamase family protein 0.0037 0.0161 0.0195
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0139 0.0805 0.1157
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0162 0.2883
Brugia malayi Dopamine receptor 0.0127 0.0728 0.1043
Echinococcus multilocularis serotonin receptor 0.0248 0.1487 0.1487
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0127 0.0728 0.2204
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0161 0.0487
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0127 0.0728 0.1935
Plasmodium vivax hypothetical protein, conserved 0.004 0.0184 0.2719
Brugia malayi hypothetical protein 0.0025 0.0086 0.0082
Onchocerca volvulus 0.0127 0.0728 0.1935
Loa Loa (eye worm) hypothetical protein 0.004 0.0184 0.0306
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Brugia malayi G-protein coupled receptor 0.0127 0.0728 0.1043
Schistosoma mansoni hypothetical protein 0.0502 0.3081 0.9329
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0127 0.0728 0.0728
Brugia malayi amine oxidase, flavin-containing family protein 0.004 0.0184 0.0229
Echinococcus granulosus g protein coupled receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis rhodopsin orphan GPCR 0.0127 0.0728 0.0728
Giardia lamblia Glycogen phosphorylase 0.0537 0.3303 1
Echinococcus granulosus Glycosyl transferase family 35 0.0537 0.3303 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0127 0.0728 0.2204
Mycobacterium ulcerans monoamine oxidase 0.004 0.0184 0.0069
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.1403 0.3984
Brugia malayi G protein-coupled receptor 0.0127 0.0728 0.1043
Echinococcus granulosus neuropeptide Y receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis Glycosyl transferase, family 35 0.0537 0.3303 0.3303
Echinococcus multilocularis protoporphyrinogen oxidase 0.004 0.0184 0.0184
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0127 0.0728 0.1043
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0127 0.0728 0.0728
Echinococcus multilocularis G protein coupled receptor 139 0.0127 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0067 0.0352 0.0827
Schistosoma mansoni neuropeptide F-like receptor 0.0127 0.0728 0.2204
Loa Loa (eye worm) hypothetical protein 0.004 0.0184 0.0306
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0067 0.0352 0.048
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.0269 0.0269
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0321 0.0971
Schistosoma mansoni adenoreceptor 0.0127 0.0728 0.2204
Schistosoma mansoni transient receptor potential channel 4 0.0196 0.1159 0.3509
Schistosoma mansoni hypothetical protein 0.0047 0.0224 0.0677
Schistosoma mansoni hypothetical protein 0.0067 0.0352 0.1065
Schistosoma mansoni hypothetical protein 0.0502 0.3081 0.9329
Loa Loa (eye worm) hypothetical protein 0.0047 0.0224 0.0429
Echinococcus multilocularis allatostatin A receptor 0.0127 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0321 0.0971
Echinococcus multilocularis rhodopsin orphan GPCR 0.0127 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0037 0.0161 0.0234
Loa Loa (eye worm) TYRA-2 protein 0.0127 0.0728 0.1996
Echinococcus granulosus neuropeptide receptor A26 0.0127 0.0728 0.2204
Brugia malayi putative neuropeptide receptor 0.0127 0.0728 0.1043
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Echinococcus granulosus rhodopsin orphan GPCR 0.0127 0.0728 0.2204
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0067 0.0352 0.0827
Echinococcus granulosus glycogen phosphorylase 0.0537 0.3303 1
Onchocerca volvulus 0.0127 0.0728 0.1935
Trypanosoma cruzi UDP-galactopyranose mutase 0.004 0.0184 0.3698
Plasmodium vivax protoporphyrinogen oxidase, putative 0.004 0.0184 0.2719
Mycobacterium leprae Probable lipase LipE 0.0037 0.0161 0.1543
Brugia malayi TAR-binding protein 0.0062 0.0321 0.0434
Schistosoma mansoni opsin-like receptor 0.0127 0.0728 0.2204
Onchocerca volvulus 0.0037 0.0161 0.0159
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0127 0.0728 0.1996
Echinococcus granulosus neuropeptide FF receptor 2 0.0127 0.0728 0.2204
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0564 0.0798
Echinococcus multilocularis g-protein coupled receptor 0.0127 0.0728 0.0728
Entamoeba histolytica glycogen phosphorylase, putative 0.0232 0.1388 0.3914
Mycobacterium tuberculosis Possible oxidoreductase 0.004 0.0184 0.0074
Echinococcus granulosus short transient receptor potential channel 6 0.0129 0.0743 0.2249
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0224 0.0289
Loa Loa (eye worm) G-protein coupled receptor 0.0127 0.0728 0.1996
Schistosoma mansoni neuropeptide receptor 0.0127 0.0728 0.2204
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0321 0.0321
Echinococcus granulosus rhodopsin orphan GPCR 0.0127 0.0728 0.2204
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0161 0.0195
Schistosoma mansoni cpg binding protein 0.0029 0.011 0.0333
Loa Loa (eye worm) hypothetical protein 0.0127 0.0728 0.1996
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0321 0.0971
Schistosoma mansoni biogenic amine receptor 0.0127 0.0728 0.2204
Schistosoma mansoni cpg binding protein 0.003 0.012 0.0364
Echinococcus granulosus 7tm_1 domain containing protein 0.0127 0.0728 0.2204
Echinococcus granulosus cpg binding protein 0.003 0.012 0.0364
Echinococcus granulosus rhodopsin orphan GPCR 0.0127 0.0728 0.2204
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0224 0.0224
Schistosoma mansoni cpg binding protein 0.003 0.012 0.0364
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0082 0.0448 1
Echinococcus granulosus glycogen phosphorylase 0.0537 0.3303 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0067 0.0352 0.048

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 1.65 mM Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10 ChEMBL. 15454240
Ki (binding) = 31.7 mM Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli ChEMBL. 15454240
Ki (binding) = 49.2 mM Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli ChEMBL. 15454240
Ki (binding) = 1.65 nM Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10 ChEMBL. 15454240
Ki (binding) = 7.43 nM Inhibitory activity against human carbonic anhydrase V expressed in Escherichia coli ChEMBL. 15454240
Ki (binding) = 7.43 nM Inhibitory activity against human carbonic anhydrase V expressed in Escherichia coli ChEMBL. 15454240
Ki (binding) = 31.7 nM Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli ChEMBL. 15454240
Ki (binding) = 49.2 nM Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli ChEMBL. 15454240

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.