Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0023 | 0.0125 | 0.0125 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.036 | 0.5095 | 0.5095 |
Mycobacterium ulcerans | lipase LipD | 0.0023 | 0.0125 | 0.0234 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.0477 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Giardia lamblia | PHD finger protein 15 | 0.002 | 0.0084 | 0.2924 |
Brugia malayi | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.1744 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0029 | 0.0217 | 0.4201 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0029 | 0.003 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0054 | 0.058 | 0.058 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0014 | 0.000000012083 | 0.000000012083 |
Mycobacterium tuberculosis | Probable reductase | 0.0106 | 0.1355 | 0.325 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Brugia malayi | Death domain containing protein | 0.0014 | 0.000000012083 | 0.000000015415 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0023 | 0.0125 | 0.0234 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) | 0.0293 | 0.4109 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Echinococcus granulosus | jumonji domain containing protein | 0.0028 | 0.0199 | 0.0199 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0031 | 0.0253 | 0.0322 |
Trichomonas vaginalis | esterase, putative | 0.0023 | 0.0125 | 0.0713 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0683 | 0.9848 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0023 | 0.0125 | 0.0234 |
Echinococcus multilocularis | peregrin | 0.002 | 0.0084 | 0.0085 |
Brugia malayi | Serotonin receptor | 0.0465 | 0.6648 | 0.8481 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0107 | 0.1367 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0054 | 0.058 | 0.1139 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0106 | 0.1355 | 0.325 |
Onchocerca volvulus | 0.0065 | 0.0751 | 1 | |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0023 | 0.0125 | 0.0234 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0107 | 0.1367 | 0.1388 |
Onchocerca volvulus | 0.0023 | 0.0125 | 0.1659 | |
Loa Loa (eye worm) | glutamate receptor | 0.0025 | 0.0162 | 0.0207 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0023 | 0.0125 | 0.0159 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.0477 | 0.0609 |
Onchocerca volvulus | 0.0065 | 0.0751 | 1 | |
Brugia malayi | hypothetical protein | 0.0065 | 0.0751 | 0.0958 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.2534 | 0.3234 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.006 | 0.0669 | 0.0679 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.0217 | 1 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0029 | 0.0217 | 0.4201 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) | 0.0293 | 0.4109 | 1 |
Echinococcus multilocularis | MAM | 0.0065 | 0.0751 | 0.0762 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0107 | 0.021 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0023 | 0.0125 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0033 | 0.0042 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0014 | 0.000000012083 | 0.000000023714 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.036 | 0.5095 | 0.6502 |
Mycobacterium tuberculosis | Conserved protein | 0.0023 | 0.0125 | 0.0234 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0364 | 0.5158 | 0.658 |
Brugia malayi | beta-lactamase family protein | 0.0023 | 0.0125 | 0.0159 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0072 | 0.0859 | 0.0859 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0079 | 0.0951 | 0.0951 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.2683 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0106 | 0.1355 | 0.325 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0029 | 0.0057 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.0217 | 0.4201 |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.0546 | 0.7836 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0023 | 0.0125 | 0.0245 |
Mycobacterium leprae | PROBABLE ISOCITRATE LYASE AceA (ISOCITRASE) (ISOCITRATASE) (ICL) | 0.0293 | 0.4109 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0144 | 0.1919 | 0.4632 |
Onchocerca volvulus | 0.0023 | 0.0125 | 0.1659 | |
Mycobacterium ulcerans | isocitrate lyase Icl | 0.0293 | 0.4109 | 1 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0364 | 0.5158 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0253 | 0.0322 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0054 | 0.058 | 0.0589 |
Brugia malayi | glutathione reductase | 0.0047 | 0.0477 | 0.0609 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0293 | 0.0374 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0023 | 0.0125 | 0.0186 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.2683 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.036 | 0.5095 | 0.65 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0107 | 0.1367 | 0.1367 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.006 | 0.0669 | 0.1313 |
Plasmodium vivax | hypothetical protein, conserved | 0.0023 | 0.0125 | 0.2131 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0107 | 0.1367 | 0.328 |
Echinococcus multilocularis | geminin | 0.0106 | 0.1359 | 0.138 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0079 | 0.0951 | 0.0965 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.002 | 0.0084 | 0.1228 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.006 | 0.0669 | 0.0853 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0021 | 0.0107 | 0.0136 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0023 | 0.0125 | 0.0245 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0106 | 0.1355 | 0.325 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.0217 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0023 | 0.0125 | 0.0234 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.002 | 0.0084 | 0.0084 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0118 | 0.153 | 0.3526 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0023 | 0.0125 | 0.0159 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0031 | 0.0251 | 0.0492 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0023 | 0.0125 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0751 | 0.0958 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.002 | 0.0084 | 0.0165 |
Brugia malayi | Protein kinase domain containing protein | 0.0014 | 0.000000012083 | 0.000000015415 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.0477 | 0.0477 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.0477 | 0.0609 |
Echinococcus granulosus | geminin | 0.0106 | 0.1359 | 0.1359 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0364 | 0.5158 | 1 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0124 | 0.0159 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0125 | 0.0186 |
Mycobacterium tuberculosis | Isocitrate lyase Icl (isocitrase) (isocitratase) | 0.0293 | 0.4109 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0023 | 0.0125 | 0.0713 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0023 | 0.0125 | 0.0234 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.328 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Schistosoma mansoni | jumonji domain containing protein | 0.0052 | 0.0553 | 0.1085 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0023 | 0.0125 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.439 | 0.5603 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0546 | 0.7839 | 1 |
Loa Loa (eye worm) | phosphofructokinase | 0.0107 | 0.1367 | 0.1745 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0951 | 0.1213 |
Mycobacterium leprae | Isocitrate lyase | 0.0137 | 0.1815 | 0.4244 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0084 | 0.0107 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0023 | 0.0124 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0479 | 0.6841 | 0.873 |
Schistosoma mansoni | hypothetical protein | 0.0106 | 0.1359 | 0.2667 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0107 | 0.1367 | 0.2609 |
Plasmodium falciparum | phd finger protein, putative | 0.002 | 0.0084 | 0.1228 |
Brugia malayi | jmjC domain containing protein | 0.0024 | 0.0146 | 0.0186 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0024 | 0.0146 | 0.0286 |
Onchocerca volvulus | Alhambra homolog | 0.002 | 0.0084 | 0.112 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0023 | 0.0125 | 0.0234 |
Echinococcus granulosus | peregrin | 0.002 | 0.0084 | 0.0084 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0107 | 0.1367 | 0.2609 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0023 | 0.0124 | 0.0244 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.006 | 0.0669 | 0.1313 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.0477 | 0.0484 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0072 | 0.0859 | 0.0872 |
Plasmodium vivax | hypothetical protein, conserved | 0.002 | 0.0084 | 0.1228 |
Onchocerca volvulus | 0.0023 | 0.0125 | 0.1659 | |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0118 | 0.153 | 0.3677 |
Mycobacterium ulcerans | beta-lactamase | 0.0023 | 0.0125 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.1745 |
Leishmania major | trypanothione reductase | 0.0047 | 0.0477 | 0.0873 |
Brugia malayi | Uncoordinated protein 44 | 0.0014 | 0.000000012083 | 0.000000015415 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0024 | 0.0146 | 0.0148 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.0217 | 0.4201 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0065 | 0.075 | 0.075 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0058 | 0.0645 | 0.0822 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0751 | 0.1474 |
Brugia malayi | PHD-finger family protein | 0.002 | 0.0084 | 0.0107 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0031 | 0.0253 | 0.0322 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0106 | 0.1355 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0751 | 0.0958 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0106 | 0.1355 | 0.325 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.0477 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.0477 | 0.0873 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0751 | 0.0958 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0124 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0125 | 0.0159 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0073 | 0.0862 | 0.1692 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.036 | 0.5095 | 0.5174 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.0217 | 0.4201 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0477 | 1 |
Mycobacterium ulcerans | isocitrate lyase AceAb | 0.0293 | 0.4109 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.0477 | 1 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0029 | 0.0217 | 0.0748 |
Brugia malayi | phosphofructokinase | 0.0107 | 0.1367 | 0.1744 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0029 | 0.0217 | 0.1406 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0106 | 0.1355 | 0.3088 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0023 | 0.0124 | 0.0124 |
Mycobacterium tuberculosis | Conserved protein | 0.0023 | 0.0125 | 0.0234 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.006 | 0.0669 | 0.0669 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0031 | 0.0251 | 0.032 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0084 | 0.0107 |
Schistosoma mansoni | hypothetical protein | 0.0106 | 0.1359 | 0.2667 |
Brugia malayi | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.1744 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0084 | 0.0165 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.006 | 0.0669 | 0.0669 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0024 | 0.0146 | 0.0146 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0107 | 0.1367 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.075 | 0.0956 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0023 | 0.0125 | 0.0713 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0024 | 0.0146 | 0.0186 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0029 | 0.0217 | 0.1406 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0023 | 0.0125 | 0.0713 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0029 | 0.5 |
Brugia malayi | beta-lactamase | 0.0023 | 0.0125 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.5158 | 0.6582 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0029 | 0.0037 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.006 | 0.0669 | 0.0679 |
Brugia malayi | hypothetical protein | 0.012 | 0.1556 | 0.1985 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0364 | 0.5158 | 1 |
Brugia malayi | Bromodomain containing protein | 0.002 | 0.0084 | 0.0107 |
Echinococcus granulosus | MAM | 0.0065 | 0.0751 | 0.0751 |
Toxoplasma gondii | ABC1 family protein | 0.0023 | 0.0125 | 0.2131 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0023 | 0.0125 | 0.0127 |
Echinococcus granulosus | Ankyrin | 0.0014 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0107 | 0.0136 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0029 | 0.0029 |
Mycobacterium tuberculosis | Conserved protein | 0.0023 | 0.0125 | 0.0234 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0016 | 0.0033 | 0.0042 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0024 | 0.0146 | 0.0286 |
Loa Loa (eye worm) | beta-lactamase | 0.0023 | 0.0125 | 0.0159 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0023 | 0.0125 | 0.0713 |
Brugia malayi | beta-lactamase family protein | 0.0023 | 0.0125 | 0.0159 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0029 | 0.5 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0064 | 0.0733 | 0.0935 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0118 | 0.153 | 0.3677 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0028 | 0.0199 | 0.0202 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0031 | 0.0253 | 0.0322 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0065 | 0.075 | 0.0761 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0029 | 0.0217 | 0.4201 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0107 | 0.1367 | 0.2609 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0014 | 0.000000012083 | 0.00000001227 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0016 | 0.0033 | 0.0042 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0023 | 0.0125 | 0.0713 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0029 | 0.0217 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.0477 | 0.0873 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.0477 | 0.1098 |
Echinococcus multilocularis | Ankyrin | 0.0014 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0016 | 0.0033 | 0.0042 |
Leishmania major | hypothetical protein, conserved | 0.0023 | 0.0125 | 0.0186 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0125 | 0.0234 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.002 | 0.0084 | 0.0085 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0107 | 0.1367 | 0.1745 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0751 | 0.1474 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0118 | 0.153 | 0.3677 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.036 | 0.5095 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0591 | 0.8496 | 0.8628 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0477 | 1 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0014 | 0.0002 | 0.0003 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.006 | 0.0669 | 0.1313 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.006 | 0.0669 | 0.0854 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.0477 | 0.0609 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0023 | 0.0125 | 0.0234 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0041 | 0.0396 | 0.0505 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.0217 | 0.4201 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.002 | 0.0084 | 0.1228 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0107 | 0.1367 | 0.3119 |
Loa Loa (eye worm) | glutamate receptor | 0.0064 | 0.0733 | 0.0936 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
RIC50 (binding) | = 0.52 | Inhibitory potency against sarco- endoplasmic reticulum calcium-ATPase in relative to thapsigargin | ChEMBL. | 15828839 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.