Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | casein kinase 2, beta polypeptide | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cysteine peptidase, putative | 0.0339 | 0.1889 | 0.1889 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0167 | 0.0602 | 0.4054 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0285 | 0.1484 | 0.1484 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.0882 | 0.0882 |
Echinococcus multilocularis | cathepsin b | 0.1425 | 1 | 1 |
Plasmodium vivax | vivapain-1 | 0.0167 | 0.0602 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.1425 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0167 | 0.0602 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0285 | 0.1484 | 0.1484 |
Echinococcus multilocularis | cathepsin b | 0.1425 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0285 | 0.1484 | 1 |
Echinococcus granulosus | cathepsin b | 0.1425 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0285 | 0.1484 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0167 | 0.0602 | 0.0602 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.05 | 0.3093 | 0.3093 |
Onchocerca volvulus | 0.0285 | 0.1484 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0285 | 0.1484 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.0882 | 0.0882 |
Onchocerca volvulus | 0.0285 | 0.1484 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0285 | 0.1484 | 0.1484 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0285 | 0.1484 | 0.1484 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0285 | 0.1484 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.0602 | 0.1945 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0339 | 0.1889 | 0.1889 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Brugia malayi | Cathepsin L-like precursor | 0.0285 | 0.1484 | 0.1484 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1425 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Brugia malayi | cathepsin L-like precursor | 0.0205 | 0.0882 | 0.0882 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0339 | 0.1889 | 0.2517 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0285 | 0.1484 | 0.1484 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.05 | 0.3093 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0285 | 0.1484 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0205 | 0.0882 | 0.0882 |
Onchocerca volvulus | 0.0285 | 0.1484 | 1 | |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0167 | 0.0602 | 0.0602 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Brugia malayi | Cathepsin L-like precursor | 0.0205 | 0.0882 | 0.0882 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Giardia lamblia | Cathepsin B precursor | 0.05 | 0.3093 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0259 | 0.1287 | 0.1287 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0167 | 0.0602 | 0.0602 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Onchocerca volvulus | 0.0205 | 0.0882 | 0.5946 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0167 | 0.0602 | 0.0602 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0205 | 0.0882 | 0.0882 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0167 | 0.0602 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0285 | 0.1484 | 0.1484 |
Toxoplasma gondii | cathepsin B | 0.05 | 0.3093 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0167 | 0.0602 | 0.1945 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0285 | 0.1484 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.05 | 0.3093 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0167 | 0.0602 | 0.0602 |
Echinococcus granulosus | cathepsin b | 0.1425 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0167 | 0.0602 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0285 | 0.1484 | 0.1484 |
Onchocerca volvulus | 0.0285 | 0.1484 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0285 | 0.1484 | 0.1484 |
Echinococcus multilocularis | cysteine protease | 0.0285 | 0.1484 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Loa Loa (eye worm) | ctsf protein | 0.0285 | 0.1484 | 0.1484 |
Loa Loa (eye worm) | hypothetical protein | 0.0285 | 0.1484 | 0.1484 |
Trypanosoma cruzi | cysteine protease, putative | 0.0167 | 0.0602 | 0.0602 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.05 | 0.3093 | 0.3093 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1425 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Loa Loa (eye worm) | fibroinase | 0.0285 | 0.1484 | 0.1484 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1425 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0167 | 0.0602 | 0.0602 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1425 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0167 | 0.0602 | 0.4054 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1425 | 1 | 1 |
Plasmodium vivax | vivapain-3 | 0.0167 | 0.0602 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0285 | 0.1484 | 0.1484 |
Giardia lamblia | Cathepsin B precursor | 0.05 | 0.3093 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.0882 | 0.0882 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0167 | 0.0602 | 0.0602 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Plasmodium vivax | vivapain-2 | 0.0285 | 0.1484 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Echinococcus multilocularis | cysteine protease | 0.0285 | 0.1484 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0285 | 0.1484 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0205 | 0.0882 | 0.5946 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.05 | 0.3093 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0167 | 0.0602 | 0.4054 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0167 | 0.0602 | 0.0602 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0285 | 0.1484 | 1 |
Echinococcus granulosus | cysteine protease | 0.0167 | 0.0602 | 0.0602 |
Onchocerca volvulus | Cathepsin F homolog | 0.0285 | 0.1484 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0205 | 0.0882 | 0.0882 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Loa Loa (eye worm) | cysteine protease | 0.0285 | 0.1484 | 0.1484 |
Leishmania major | cathepsin L-like protease | 0.0339 | 0.1889 | 0.2517 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0339 | 0.1889 | 0.1889 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0167 | 0.0602 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0167 | 0.0602 | 0.0602 |
Onchocerca volvulus | Cathepsin L homolog | 0.0285 | 0.1484 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0339 | 0.1889 | 0.1889 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0205 | 0.0882 | 0.2853 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0285 | 0.1484 | 0.1484 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Brugia malayi | Cathepsin L-like precursor | 0.0285 | 0.1484 | 0.1484 |
Echinococcus granulosus | cathepsin l1 | 0.0285 | 0.1484 | 0.1484 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0285 | 0.1484 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Echinococcus granulosus | cathepsin L | 0.0167 | 0.0602 | 0.0602 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0285 | 0.1484 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0167 | 0.0602 | 0.0602 |
Onchocerca volvulus | 0.0285 | 0.1484 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0285 | 0.1484 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Onchocerca volvulus | 0.0285 | 0.1484 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.05 | 0.3093 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Echinococcus granulosus | cathepsin l1 | 0.0205 | 0.0882 | 0.0882 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0141 | 0.0405 | 0.0405 |
Toxoplasma gondii | cathepsin CPL | 0.0285 | 0.1484 | 0.4799 |
Plasmodium vivax | unspecified product | 0.0167 | 0.0602 | 0.4054 |
Onchocerca volvulus | Cathepsin L homolog | 0.0285 | 0.1484 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0285 | 0.1484 | 0.1484 |
Onchocerca volvulus | 0.0285 | 0.1484 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0339 | 0.1889 | 0.2517 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0285 | 0.1484 | 0.1484 |
Loa Loa (eye worm) | cathepsin B | 0.05 | 0.3093 | 0.3093 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0339 | 0.1889 | 0.5168 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Entamoeba histolytica | cysteine protease, putative | 0.0167 | 0.0602 | 0.4054 |
Echinococcus multilocularis | cathepsin L | 0.0167 | 0.0602 | 0.0602 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0205 | 0.0882 | 0.2853 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0285 | 0.1484 | 0.4799 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.