Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0152 | 0.1236 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0733 | 0.7119 | 0.7109 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0033 | 0.0035 | 0.5 |
Onchocerca volvulus | 0.0152 | 0.1236 | 1 | |
Leishmania major | carnitine/choline acetyltransferase, putative | 0.0152 | 0.1236 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0033 | 0.0035 | 0.5 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0152 | 0.1236 | 0.1205 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0152 | 0.1236 | 1 |
Schistosoma mansoni | choline o-acyltransferase | 0.0152 | 0.1236 | 0.1205 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0152 | 0.1236 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0033 | 0.0035 | 0.5 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0152 | 0.1236 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0874 | 0.0842 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0152 | 0.1236 | 0.1205 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0152 | 0.1236 | 0.1205 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0874 | 0.0842 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0152 | 0.1236 | 1 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0152 | 0.1236 | 1 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0623 | 0.6013 | 0.5999 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0152 | 0.1236 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0033 | 0.0035 | 0.5 |
Onchocerca volvulus | 0.0152 | 0.1236 | 1 | |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.1017 | 1 | 1 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0152 | 0.1236 | 1 |
Trypanosoma cruzi | carnitine O-acetyltransferase, putative | 0.0152 | 0.1236 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0152 | 0.1236 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0152 | 0.1236 | 1 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.0152 | 0.1236 | 0.1205 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0152 | 0.1236 | 0.1205 |
Brugia malayi | hypothetical protein | 0.0116 | 0.0874 | 0.0842 |
Onchocerca volvulus | 0.0152 | 0.1236 | 1 | |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0152 | 0.1236 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1017 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0152 | 0.1236 | 1 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.003 | 0 | 0.5 |
Trypanosoma cruzi | choline/carnitine O-acetyltransferase, putative | 0.0152 | 0.1236 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1236 | 0.1205 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0152 | 0.1236 | 0.1205 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0152 | 0.1236 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0152 | 0.1236 | 1 |
Brugia malayi | Choline O-acetyltransferase | 0.1017 | 1 | 1 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.0152 | 0.1236 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0033 | 0.0035 | 0.5 |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0152 | 0.1236 | 1 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0152 | 0.1236 | 0.1205 |
Echinococcus multilocularis | choline O acetyltransferase | 0.1017 | 1 | 1 |
Echinococcus granulosus | choline O acetyltransferase | 0.1017 | 1 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0623 | 0.6013 | 0.5999 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0033 | 0.0035 | 0.5 |
Schistosoma mansoni | choline o-acyltransferase | 0.1017 | 1 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0033 | 0.0035 | 0.5 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.0152 | 0.1236 | 0.1205 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0152 | 0.1236 | 0.1205 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0623 | 0.6013 | 0.5999 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.003 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0152 | 0.1236 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0152 | 0.1236 | 1 |
Onchocerca volvulus | 0.0152 | 0.1236 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.