Detailed information for compound 547996

Basic information

Technical information
  • TDR Targets ID: 547996
  • Name: (3S,4S)-1-[(4-fluoranylphenyl)methyl]-3-(4-ph enyl-1-piperidyl)piperidin-4-ol
  • MW: 367.49 | Formula: C23H29FN2O
  • H donors: 1 H acceptors: 1 LogP: 3.71 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@H]1CCN(C[C@@H]1N1CCC(CC1)c1ccccc1)Cc1ccc(cc1)[18F]
  • InChi: 1S/C23H29FN2O/c24-21-8-6-18(7-9-21)16-25-13-12-23(27)22(17-25)26-14-10-20(11-15-26)19-4-2-1-3-5-19/h1-9,20,22-23,27H,10-17H2/t22-,23-/m0/s1/i24-1
  • InChiKey: HPZHSYBCGLDRCT-NOAXBIBBSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (3S,4S)-1-[(4-fluoranylphenyl)methyl]-3-(4-phenyl-1-piperidinyl)-4-piperidinol
  • (3S,4S)-1-[(4-fluoranylphenyl)methyl]-3-(4-phenylpiperidin-1-yl)piperidin-4-ol
  • (3S,4S)-1-(4-fluoranylbenzyl)-3-(4-phenylpiperidino)piperidin-4-ol
  • 4-fluorobenzyltrozamicol
  • 154824-77-8
  • (1,3'-Bipiperidin)-4'-ol, 1'-((4-(fluoro-18F)phenyl)methyl)-4-phenyl-, trans-(+)-
  • 1'-((4-(Fluoro-18F)phenyl)methyl)-4-phenyl-(1,3'-bipiperidin)-4'-ol trans-(+)-
  • p-(18F)Fluorobenzyltrozamicol
  • p-FBT

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.004 0.0028 0.0051
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0686 0.4209 1
Echinococcus multilocularis tensin 0.0428 0.2538 0.6029
Echinococcus multilocularis epidermal growth factor receptor 0.0258 0.144 0.3422
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0428 0.2538 0.6029
Echinococcus granulosus 7TM GPCR rhodopsin 0.004 0.0028 0.0028
Echinococcus multilocularis snurportin 1 0.0305 0.1744 0.4144
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0428 0.2538 0.4592
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0428 0.2538 0.2538
Loa Loa (eye worm) TK protein kinase 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0258 0.144 0.3422
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0258 0.144 0.3422
Echinococcus multilocularis neuropeptides capa receptor 0.004 0.0028 0.0067
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0428 0.2538 0.2538
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.144 0.3422
Brugia malayi Variant SH3 domain containing protein 0.0428 0.2538 0.4592
Loa Loa (eye worm) TK/ALK protein kinase 0.0258 0.144 0.2606
Schistosoma mansoni tensin-related 0.0428 0.2538 0.6029
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0258 0.144 0.144
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0258 0.144 0.2606
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0258 0.144 0.3422
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis protein kinase 0.0258 0.144 0.3422
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Loa Loa (eye worm) TK protein kinase 0.0258 0.144 0.2606
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0031 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0028 0.0028
Loa Loa (eye worm) neuropeptide F receptor 0.004 0.0028 0.0051
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0268 0.1507 0.024
Brugia malayi Tyrosine-protein kinase abl-1 0.0686 0.4209 0.7617
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Brugia malayi Tensin 0.0428 0.2538 0.4592
Entamoeba histolytica hypothetical protein 0.0268 0.1507 0.024
Brugia malayi nuclear hormone receptor 0.004 0.0031 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0428 0.2538 0.6029
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0056
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0686 0.4209 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0056
Echinococcus multilocularis protein KINase family member (kin 25) 0.0258 0.144 0.3422
Echinococcus multilocularis raf serine:threonine protein kinase 0.0258 0.144 0.3422
Echinococcus granulosus tyrosine protein kinase Srms 0.0686 0.4209 0.4209
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Echinococcus multilocularis neuropeptide receptor A26 0.004 0.0028 0.0067
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0258 0.144 0.3422
Echinococcus granulosus retinal guanylyl cyclase 2 0.0258 0.144 0.144
Schistosoma mansoni amine GPCR 0.004 0.0028 0.0067
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0258 0.144 0.2606
Onchocerca volvulus 0.004 0.0028 0.0067
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.004 0.0028 0.0067
Schistosoma mansoni neuropeptide receptor 0.004 0.0028 0.0067
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0258 0.144 0.2606
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0031 0.0073
Echinococcus granulosus neuropeptide receptor A26 0.004 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) TK/RYK protein kinase 0.0258 0.144 0.2606
Loa Loa (eye worm) RGC/RGC protein kinase 0.0258 0.144 0.2606
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0258 0.144 1
Loa Loa (eye worm) TK protein kinase 0.0258 0.144 0.2606
Echinococcus multilocularis neuropeptide Y receptor 0.004 0.0028 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0258 0.144 1
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0686 0.4209 1
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Loa Loa (eye worm) TK/FER protein kinase 0.0258 0.144 0.2606
Echinococcus granulosus tyrosine protein kinase csk 0.0258 0.144 0.144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0028 0.0067
Onchocerca volvulus 0.0258 0.144 0.3422
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0028 0.0067
Onchocerca volvulus Neuropeptide F receptor homolog 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0258 0.144 0.3422
Loa Loa (eye worm) TK/FER protein kinase 0.0686 0.4209 0.7617
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0428 0.2538 0.4592
Loa Loa (eye worm) G-protein coupled receptor 0.004 0.0028 0.0051
Echinococcus granulosus tyrosine protein kinase Fyn 0.0686 0.4209 0.4209
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0028 0.0028
Schistosoma mansoni ephrin receptor 0.0258 0.144 0.3422
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0258 0.144 0.144
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Echinococcus granulosus growth factor receptor bound protein 2 0.0428 0.2538 0.2538
Echinococcus granulosus neuropeptide FF receptor 2 0.004 0.0028 0.0028
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0258 0.144 0.3422
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0258 0.144 0.3422
Echinococcus multilocularis serotonin receptor 0.004 0.0028 0.0067
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0258 0.144 0.144
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi larval opioid receptor 0.004 0.0028 0.0051
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0428 0.2538 0.6029
Onchocerca volvulus 0.0686 0.4209 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Onchocerca volvulus 0.004 0.0028 0.0067
Schistosoma mansoni suppressor of cytokine signaling 0.0428 0.2538 0.6029
Loa Loa (eye worm) serine/threonine protein kinase 0.0258 0.144 0.2606
Onchocerca volvulus 0.004 0.0028 0.0067
Echinococcus multilocularis signal transduction protein lnk realted 0.0428 0.2538 0.6029
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus multilocularis growth factor receptor bound protein 2 0.0428 0.2538 0.6029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.004 0.0028 0.0067
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0258 0.144 0.3422
Echinococcus multilocularis sex peptide receptor 0.004 0.0028 0.0067
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Onchocerca volvulus 0.0428 0.2538 0.6029
Echinococcus multilocularis NCK adaptor protein 0.0428 0.2538 0.6029
Schistosoma mansoni neuropeptide F-like receptor 0.004 0.0028 0.0067
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0031 0.0031
Leishmania major C-8 sterol isomerase-like protein 0.0889 0.5526 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.004 0.0028 0.0051
Schistosoma mansoni hypothetical protein 0.0428 0.2538 0.6029
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0031 0.0073
Onchocerca volvulus 0.004 0.0028 0.0067
Leishmania major protein kinase, putative 0.0258 0.144 0.2606
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Brugia malayi neuropeptide F receptor 0.004 0.0028 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi Protein kinase domain containing protein 0.0686 0.4209 0.7617
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0258 0.144 0.144
Giardia lamblia Kinase, NEK 0.0258 0.144 0.5
Brugia malayi Guanylyl cyclase protein 23 0.0258 0.144 0.2606
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0028 0.0067
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni hypothetical protein 0.004 0.0028 0.0067
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0686 0.4209 0.4209
Echinococcus granulosus 7tm_1 domain containing protein 0.004 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.004 0.0028 0.0067
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0428 0.2538 0.6029
Echinococcus granulosus peptide allatostatin:somatostatin 0.004 0.0028 0.0028
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.004 0.0028 0.0067
Schistosoma mansoni hypothetical protein 0.0305 0.1744 0.4144
Brugia malayi SH2 domain containing protein 0.0428 0.2538 0.4592
Echinococcus granulosus tyrosine protein kinase Src42A 0.0686 0.4209 0.4209
Schistosoma mansoni tyrosine kinase 0.0686 0.4209 1
Schistosoma mansoni tyrosine kinase 0.0686 0.4209 1
Onchocerca volvulus 0.0258 0.144 0.3422
Echinococcus granulosus tyrosine protein kinase ABL1 0.0686 0.4209 0.4209
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0028 0.0067
Echinococcus multilocularis SH2 motif 0.0428 0.2538 0.6029
Echinococcus granulosus tyrosine protein kinase Blk 0.0686 0.4209 0.4209
Entamoeba histolytica hypothetical protein 0.0268 0.1507 0.024
Echinococcus multilocularis kinase suppressor of Ras 1 0.0258 0.144 0.3422
Brugia malayi hypothetical protein 0.004 0.0028 0.0051
Trypanosoma cruzi protein kinase, putative 0.0258 0.144 0.2606
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.144 0.3422
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0258 0.144 0.2606
Echinococcus granulosus snurportin 1 0.0305 0.1744 0.1744
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Brugia malayi Protein kinase domain containing protein 0.0686 0.4209 0.7617
Onchocerca volvulus 0.004 0.0028 0.0067
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.004 0.0028 0.0067
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0028 0.0028
Onchocerca volvulus 0.004 0.0028 0.0067
Echinococcus granulosus fibroblast growth factor receptor 4 0.0258 0.144 0.144
Schistosoma mansoni growth factor receptor-bound protein 0.0428 0.2538 0.6029
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0028 0.0028
Echinococcus multilocularis neuropeptide Y receptor 0.004 0.0028 0.0067
Brugia malayi RE15519p 0.004 0.0028 0.0051
Onchocerca volvulus 0.004 0.0028 0.0067
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0258 0.144 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni amine GPCR 0.004 0.0028 0.0067
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0258 0.144 0.2606
Echinococcus multilocularis activin receptor type 0.0258 0.144 0.3422
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0031 0.0073
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Onchocerca volvulus 0.0686 0.4209 1
Schistosoma mansoni biogenic amine receptor 0.004 0.0028 0.0067
Echinococcus granulosus tyrosine protein kinase HCK 0.0258 0.144 0.144
Schistosoma mansoni tyrosine protein kinase 0.0258 0.144 0.3422
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi SH2 domain containing protein 0.0428 0.2538 0.4592
Schistosoma mansoni tyrosine kinase 0.0686 0.4209 1
Echinococcus granulosus SH2 motif 0.0428 0.2538 0.2538
Echinococcus granulosus hypothetical protein 0.0428 0.2538 0.2538
Brugia malayi tRNA modification GTPase TrmE family protein 0.0428 0.2538 0.4592
Schistosoma mansoni hypothetical protein 0.0258 0.144 0.3422
Brugia malayi GnHR receptor homolog 0.004 0.0028 0.0051
Brugia malayi Variant SH3 domain containing protein 0.0428 0.2538 0.4592
Plasmodium falciparum protein kinase, putative 0.0258 0.144 0.5
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0031 0.0056
Brugia malayi Receptor family ligand binding region containing protein 0.0258 0.144 0.2606
Echinococcus multilocularis 0.0428 0.2538 0.6029
Brugia malayi Raf kinase 0.0258 0.144 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0031 0.0073
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Onchocerca volvulus Tyrosine kinase homolog 0.0258 0.144 0.3422
Echinococcus granulosus serotonin receptor 0.004 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0056
Brugia malayi integrin-linked kinase 0.0258 0.144 0.2606
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0428 0.2538 0.6029
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0686 0.4209 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0028 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0258 0.144 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0258 0.144 0.3422
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0686 0.4209 0.4209
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0686 0.4209 1
Brugia malayi hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0686 0.4209 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0028 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0028 0.0067
Brugia malayi hypothetical protein 0.0258 0.144 0.2606
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0258 0.144 0.3422
Echinococcus granulosus neuropeptide receptor 0.004 0.0028 0.0028
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0031 0.0056
Brugia malayi Serotonin receptor 0.004 0.0028 0.0051
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0031 0.0056
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0031 0.0073
Brugia malayi Melatonin receptor type 1A 0.004 0.0028 0.0051
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Echinococcus multilocularis g-protein coupled receptor 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Loa Loa (eye worm) SH2 domain-containing protein 0.0428 0.2538 0.4592
Onchocerca volvulus 0.004 0.0028 0.0067
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0031 0.0073
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Echinococcus granulosus protein kinase 0.0258 0.144 0.144
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0686 0.4209 1
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0258 0.144 0.2606
Brugia malayi hypothetical protein 0.004 0.0028 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0428 0.2538 0.6029
Brugia malayi ecdysteroid receptor 0.004 0.0031 0.0056
Schistosoma mansoni thyroid hormone receptor 0.004 0.0031 0.0073
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Onchocerca volvulus 0.004 0.0028 0.0067
Onchocerca volvulus 0.0428 0.2538 0.6029
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0056
Echinococcus granulosus neuropeptides capa receptor 0.004 0.0028 0.0028
Echinococcus granulosus tyrosine kinase 0.0258 0.144 0.144
Echinococcus multilocularis tyrosine protein kinase csk 0.0258 0.144 0.3422
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0031 0.0073
Schistosoma mansoni signal transduction protein lnk-related 0.0428 0.2538 0.6029
Echinococcus multilocularis dro:myosuppressin receptor 0.004 0.0028 0.0067
Trypanosoma brucei Pseudokinase, putative 0.0258 0.144 0.2606
Echinococcus multilocularis tyrosine protein kinase shark 0.0686 0.4209 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0056
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.004 0.0028 0.0067
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Schistosoma mansoni adenoreceptor 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis allatostatin A receptor 0.004 0.0028 0.0067
Echinococcus granulosus g protein coupled receptor 0.004 0.0028 0.0028
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0031 0.0031
Onchocerca volvulus 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0028 0.0067
Echinococcus granulosus kinase suppressor of Ras 1 0.0258 0.144 0.144
Echinococcus granulosus neuropeptide Y receptor 0.004 0.0028 0.0028
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0031 0.0073
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis fmrfamide receptor 0.004 0.0028 0.0067
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0686 0.4209 0.4209
Toxoplasma gondii protein kinase 0.0258 0.144 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0428 0.2538 0.4592
Echinococcus granulosus g protein coupled receptor 0.004 0.0028 0.0028
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0686 0.4209 1
Echinococcus multilocularis fmrfamide receptor 0.004 0.0028 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0028 0.0067
Echinococcus multilocularis natriuretic peptide receptor 1 0.0258 0.144 0.3422
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0031 0.0073
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Plasmodium vivax tyrosine kinase-like protein, putative 0.0258 0.144 1
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0428 0.2538 0.6029
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0258 0.144 0.2606
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Echinococcus granulosus G protein coupled receptor 139 0.004 0.0028 0.0028
Loa Loa (eye worm) TK/FER protein kinase 0.0686 0.4209 0.7617
Echinococcus multilocularis tensin 0.0428 0.2538 0.6029
Loa Loa (eye worm) hypothetical protein 0.0455 0.2711 0.4907
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0686 0.4209 0.4209
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Echinococcus granulosus ephrin type A receptor 4 A 0.0258 0.144 0.144
Entamoeba histolytica SH2 domain containing protein 0.0428 0.2538 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni growth hormone secretagogue receptor 0.004 0.0028 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0686 0.4209 1
Giardia lamblia Kinase 0.0258 0.144 0.5
Onchocerca volvulus 0.004 0.0028 0.0067
Loa Loa (eye worm) TK protein kinase 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0031 0.0073
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0258 0.144 0.144
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.0258 0.144 0.2606
Leishmania major hypothetical protein, conserved 0.0258 0.144 0.2606
Schistosoma mansoni histamine h1 receptor 0.004 0.0028 0.0067
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0028 0.0067
Onchocerca volvulus 0.004 0.0031 0.0073
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0031 0.0031
Schistosoma mansoni neuropeptide receptor 0.004 0.0028 0.0067
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0258 0.144 0.2606
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.004 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Loa Loa (eye worm) follicle stimulating hormone receptor 0.004 0.0028 0.0051
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0258 0.144 0.3422
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0031 0.0073
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0056
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0258 0.144 0.144
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Giardia lamblia Protein 21.1 0.0258 0.144 0.5
Echinococcus granulosus neuropeptide receptor 0.004 0.0028 0.0028
Plasmodium falciparum tyrosine kinase-like protein 0.0258 0.144 0.5
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni amine GPCR 0.004 0.0028 0.0067
Echinococcus granulosus c src tyrosine kinase 0.0686 0.4209 0.4209
Schistosoma mansoni neuropeptide receptor 0.004 0.0028 0.0067
Echinococcus granulosus tyrosine protein kinase Fyn 0.0686 0.4209 0.4209
Loa Loa (eye worm) TK/FER protein kinase 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0031 0.0056
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Echinococcus granulosus alpha 1A adrenergic receptor 0.004 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis heat shock protein 70 0.0258 0.144 0.3422
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Loa Loa (eye worm) SH2 domain-containing protein 0.0428 0.2538 0.4592
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0031 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) TK protein kinase 0.0258 0.144 0.2606
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0031 0.0056
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Echinococcus multilocularis serotonin receptor 0.004 0.0028 0.0067
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0428 0.2538 0.4592
Echinococcus granulosus SHC transforming protein 3 0.0428 0.2538 0.2538
Echinococcus granulosus tyrosine protein kinase 0.0258 0.144 0.144
Loa Loa (eye worm) TK/Met protein kinase 0.0258 0.144 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus granulosus tyrosine kinase 0.0686 0.4209 0.4209
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0428 0.2538 0.6029
Echinococcus granulosus neuropeptides capa receptor 0.004 0.0028 0.0028
Echinococcus multilocularis ephrin type A receptor 4 A 0.0258 0.144 0.3422
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0031 0.0056
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Echinococcus multilocularis insulin receptor 0.0258 0.144 0.3422
Trichomonas vaginalis conserved hypothetical protein 0.0258 0.144 1
Echinococcus multilocularis tyrosine kinase 0.0686 0.4209 1
Brugia malayi SH2 domain containing protein 0.0428 0.2538 0.4592
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis receptor type guanylyl cyclase 0.0258 0.144 0.3422
Loa Loa (eye worm) TK/FAK protein kinase 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.0686 0.4209 0.7617
Echinococcus granulosus tyrosine protein kinase csk 0.0258 0.144 0.144
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Onchocerca volvulus 0.004 0.0028 0.0067
Trichomonas vaginalis STE family protein kinase 0.0258 0.144 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0028 0.0067
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0028 0.0067
Schistosoma mansoni serine/threonine RGC 0.0258 0.144 0.3422
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Brugia malayi C-terminal src kinase protein 1 0.0258 0.144 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.004 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.0686 0.4209 0.7617
Loa Loa (eye worm) hypothetical protein 0.0686 0.4209 0.7617
Echinococcus multilocularis SH2 motif 0.0428 0.2538 0.6029
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.144 0.3422
Echinococcus granulosus thyrotropin releasing hormone receptor 0.004 0.0028 0.0028
Loa Loa (eye worm) RGC/RGC protein kinase 0.0258 0.144 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0031 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus granulosus tyrosine protein kinase shark 0.0686 0.4209 0.4209
Echinococcus granulosus neuropeptide Y receptor 0.004 0.0028 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0028 0.0067
Echinococcus multilocularis epidermal growth factor receptor 0.0258 0.144 0.3422
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0428 0.2538 0.4592
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Loa Loa (eye worm) TK/FER protein kinase 0.0258 0.144 0.2606
Echinococcus multilocularis neuropeptide receptor 0.004 0.0028 0.0067
Echinococcus granulosus tyrosine protein kinase Fyn 0.0686 0.4209 0.4209
Loa Loa (eye worm) TK/ACK protein kinase 0.0258 0.144 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0031 0.0056
Echinococcus granulosus SH2 domain containing protein 7 0.0428 0.2538 0.2538
Schistosoma mansoni tensin 0.0428 0.2538 0.6029
Brugia malayi neuropeptide F receptor 0.004 0.0028 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0258 0.144 0.2606
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0258 0.144 0.2606
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0031 0.0056
Trypanosoma brucei Flagellum attachment zone protein 20 0.0258 0.144 0.2606
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Onchocerca volvulus 0.0258 0.144 0.3422
Onchocerca volvulus 0.0258 0.144 0.3422
Echinococcus multilocularis neuropeptide s receptor 0.004 0.0028 0.0067
Loa Loa (eye worm) STAT protein 0.0428 0.2538 0.4592
Schistosoma mansoni neuropeptide receptor 0.004 0.0028 0.0067
Trypanosoma cruzi protein kinase, putative 0.0258 0.144 0.2606
Echinococcus multilocularis G-protein coupled receptor, putative 0.004 0.0028 0.0067
Brugia malayi steroid hormone receptor 0.004 0.0031 0.0056
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0258 0.144 0.2606
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0889 0.5526 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.004 0.0028 0.0067
Echinococcus multilocularis neuropeptide receptor 0.004 0.0028 0.0067
Brugia malayi cytokine inducible SH2-containing protein 5 0.0428 0.2538 0.4592
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0028 0.0028
Echinococcus granulosus hypothetical protein 0.004 0.0028 0.0028
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.004 0.0028 0.0067
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0258 0.144 0.3422
Schistosoma mansoni opsin-like receptor 0.004 0.0028 0.0067
Loa Loa (eye worm) TK/FER protein kinase 0.0686 0.4209 0.7617
Echinococcus granulosus receptor type guanylyl cyclase 0.0258 0.144 0.144
Entamoeba histolytica hypothetical protein 0.0268 0.1507 0.024
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0428 0.2538 0.6029
Onchocerca volvulus 0.0258 0.144 0.3422
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0028 0.0067
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.004 0.0028 0.0067
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.004 0.0028 0.0051
Echinococcus multilocularis protein kinase 0.0258 0.144 0.3422
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0028 0.0067
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0031 0.0031
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Loa Loa (eye worm) TK/FER protein kinase 0.0258 0.144 0.2606
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0028 0.0028
Brugia malayi Sex muscle abnormal protein 5 0.0428 0.2538 0.4592
Echinococcus multilocularis neuropeptides capa receptor 0.004 0.0028 0.0067
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Echinococcus multilocularis activated cdc42 kinase 1 0.0258 0.144 0.3422
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Brugia malayi Dopamine receptor protein 1 0.004 0.0028 0.0051
Schistosoma mansoni hypothetical protein 0.004 0.0028 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0258 0.144 0.2606
Echinococcus multilocularis neuropeptide FF receptor 2 0.004 0.0028 0.0067
Echinococcus granulosus somatostatin receptor 0.004 0.0028 0.0028
Loa Loa (eye worm) TYRA-2 protein 0.004 0.0028 0.0051
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0031 0.0073
Echinococcus granulosus epidermal growth factor receptor 0.0258 0.144 0.144
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Loa Loa (eye worm) TK/CSK protein kinase 0.0258 0.144 0.2606
Echinococcus granulosus N chimaerin 0.0428 0.2538 0.2538
Brugia malayi Protein kinase domain containing protein 0.0686 0.4209 0.7617
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0258 0.144 0.2606
Schistosoma mansoni tyrosine kinase 0.0686 0.4209 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0258 0.144 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0028 0.0067
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0258 0.144 1
Schistosoma mansoni opsin-like receptor 0.004 0.0028 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) TK/FER protein kinase 0.0686 0.4209 0.7617
Onchocerca volvulus 0.004 0.0028 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0031 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0258 0.144 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0686 0.4209 1
Brugia malayi Variant SH3 domain containing protein 0.0428 0.2538 0.4592
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0428 0.2538 0.2538
Plasmodium falciparum protein kinase, putative 0.0258 0.144 0.5
Schistosoma mansoni tensin 0.0428 0.2538 0.6029
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.0258 0.144 0.2606
Mycobacterium ulcerans lipase LipD 0.0036 0 0.5
Echinococcus granulosus tyrosine protein kinase csk 0.0258 0.144 0.144
Echinococcus multilocularis vesicular acetylcholine transporter 0.0267 0.1497 0.3557
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni tyrosine kinase 0.0686 0.4209 1
Echinococcus granulosus natriuretic peptide receptor 1 0.0258 0.144 0.144
Brugia malayi hypothetical protein 0.004 0.0028 0.0051
Brugia malayi follicle stimulating hormone receptor 0.004 0.0028 0.0051
Loa Loa (eye worm) TK/DDR protein kinase 0.0258 0.144 0.2606
Echinococcus granulosus vesicular acetylcholine transporter 0.0267 0.1497 0.1497
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0258 0.144 0.3422
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0428 0.2538 0.6029
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0031 0.0073
Schistosoma mansoni tyrosine kinase 0.0686 0.4209 1
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0028 0.0028
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Brugia malayi putative neuropeptide receptor NPR1 0.004 0.0028 0.0051
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Echinococcus multilocularis tyrosine protein kinase HCK 0.0258 0.144 0.3422
Brugia malayi hypothetical protein 0.004 0.0028 0.0051
Echinococcus granulosus signal transduction protein lnk realted 0.0428 0.2538 0.2538
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0031 0.0031
Brugia malayi SH2 domain containing protein 0.0428 0.2538 0.4592
Loa Loa (eye worm) TK/FER protein kinase 0.0686 0.4209 0.7617
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0258 0.144 0.2606
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0686 0.4209 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.004 0.0028 0.0067
Echinococcus granulosus g protein coupled receptor 0.004 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0686 0.4209 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0428 0.2538 0.6029
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Trypanosoma brucei C-8 sterol isomerase, putative 0.0889 0.5526 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0258 0.144 0.2606
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni GTPase activating protein 0.0428 0.2538 0.6029
Schistosoma mansoni SH2A 0.0428 0.2538 0.6029
Loa Loa (eye worm) TK/INSR protein kinase 0.0258 0.144 0.2606
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi nuclear receptor NHR-88 0.004 0.0031 0.0056
Loa Loa (eye worm) TK/ABL protein kinase 0.0686 0.4209 0.7617
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0889 0.5526 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0031 0.0031
Echinococcus granulosus g-protein coupled receptor 0.004 0.0028 0.0028
Loa Loa (eye worm) TK protein kinase 0.0258 0.144 0.2606
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0428 0.2538 0.6029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0258 0.144 0.2606
Trichomonas vaginalis conserved hypothetical protein 0.0258 0.144 1
Brugia malayi Variant SH3 domain containing protein 0.0428 0.2538 0.4592
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0031 0.0056
Onchocerca volvulus 0.0258 0.144 0.3422
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.144 0.3422
Echinococcus multilocularis tyrosine protein kinase 0.0258 0.144 0.3422
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.004 0.0028 0.0067
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0028 0.0067
Brugia malayi gonadotropin-releasing hormone receptor 2 0.004 0.0028 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi SH2 domain containing protein 0.0686 0.4209 0.7617
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus granulosus neuropeptide s receptor 0.004 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0428 0.2538 0.4592
Echinococcus multilocularis tachykinin peptides receptor 99D 0.004 0.0028 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Onchocerca volvulus 0.004 0.0028 0.0067
Plasmodium vivax tyrosine kinase-like protein, putative 0.0258 0.144 1
Brugia malayi ORL1-like opioid receptor 0.004 0.0028 0.0051
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0258 0.144 0.2606
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0031 0.0056
Loa Loa (eye worm) TK protein kinase 0.0686 0.4209 0.7617
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Brugia malayi vesicular acetylcholine transporter unc-17 0.0267 0.1497 0.2709
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis protein tyrosine kinase 0.0258 0.144 0.3422
Brugia malayi Immunoglobulin I-set domain containing protein 0.0258 0.144 0.2606
Echinococcus multilocularis SH2 domain containing protein 7 0.0428 0.2538 0.6029
Schistosoma mansoni amine GPCR 0.004 0.0028 0.0067
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Schistosoma mansoni nuclear hormone receptor 0.004 0.0031 0.0073
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0031 0.0073
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Echinococcus granulosus integrin linked protein kinase 0.0258 0.144 0.144
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Onchocerca volvulus 0.0258 0.144 0.3422
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0258 0.144 0.144
Echinococcus granulosus expressed conserved protein 0.0428 0.2538 0.2538
Toxoplasma gondii protein kinase domain-containing protein 0.0258 0.144 1
Echinococcus multilocularis SH2 motif 0.0428 0.2538 0.6029
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.004 0.0028 0.0067
Echinococcus multilocularis c src tyrosine kinase 0.0686 0.4209 1
Trypanosoma brucei protein kinase, putative 0.0258 0.144 0.2606
Echinococcus granulosus tensin 0.0428 0.2538 0.2538
Schistosoma mansoni myosin xvIII 0.004 0.0028 0.0067
Echinococcus granulosus tyrosine protein kinase pr2 0.0258 0.144 0.144
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.004 0.0028 0.0067
Echinococcus granulosus NCK adaptor protein 0.0428 0.2538 0.2538
Echinococcus multilocularis N chimaerin 0.0428 0.2538 0.6029
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.004 0.0028 0.0028
Loa Loa (eye worm) protein kinase domain-containing protein 0.0258 0.144 0.2606
Brugia malayi sulfakinin receptor protein 0.004 0.0028 0.0051
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0258 0.144 0.144
Schistosoma mansoni biogenic amine receptor 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis tyrosine kinase 0.0258 0.144 0.3422
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0428 0.2538 0.2538
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0028 0.0067
Echinococcus multilocularis tyrosine protein kinase csk 0.0258 0.144 0.3422
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0258 0.144 0.3422
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0031 0.0056
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0031 0.0056
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0258 0.144 0.2606
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0031 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0258 0.144 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus granulosus retinal guanylyl cyclase 2 0.0258 0.144 0.144
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Brugia malayi bone morphogenetic protein type 1 receptor 0.0258 0.144 0.2606
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.004 0.0028 0.0051
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.004 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase Abl 0.0686 0.4209 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0258 0.144 0.3422
Schistosoma mansoni protein tyrosine kinase 0.0258 0.144 0.3422
Onchocerca volvulus 0.0686 0.4209 1
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.004 0.0028 0.0028
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0428 0.2538 0.6029
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.004 0.0028 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0258 0.144 0.3422
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0031 0.0031
Onchocerca volvulus 0.0686 0.4209 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni ephrin receptor 0.0258 0.144 0.3422
Mycobacterium leprae Probable lipase LipE 0.0036 0 0.5
Loa Loa (eye worm) TK/FER protein kinase 0.0258 0.144 0.2606
Echinococcus granulosus epidermal growth factor receptor 0.0258 0.144 0.144
Schistosoma mansoni amine GPCR 0.004 0.0028 0.0067
Brugia malayi Furin-like cysteine rich region family protein 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Onchocerca volvulus 0.0686 0.4209 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.004 0.0028 0.0067
Schistosoma mansoni suppressor of cytokine signaling 0.0428 0.2538 0.6029
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0686 0.4209 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0031 0.0073
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Onchocerca volvulus 0.004 0.0028 0.0067
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Trichomonas vaginalis conserved hypothetical protein 0.0258 0.144 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0028 0.0067
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0031 0.0056
Schistosoma mansoni opsin-like receptor 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni hypothetical protein 0.004 0.0028 0.0067
Brugia malayi SH2 domain containing protein 0.0428 0.2538 0.4592
Leishmania major protein kinase, putative 0.0258 0.144 0.2606
Echinococcus granulosus activated cdc42 kinase 1 0.0258 0.144 0.144
Toxoplasma gondii STE kinase 0.0258 0.144 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.004 0.0028 0.0067
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.1245 1
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0267 0.1497 0.3557
Plasmodium falciparum protein kinase, putative 0.0258 0.144 0.5
Schistosoma mansoni vav2 0.0428 0.2538 0.6029
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0428 0.2538 0.6029
Brugia malayi putative neuropeptide receptor 0.004 0.0028 0.0051
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0028 0.0028
Brugia malayi Tyrosine-protein kinase PR2 0.0258 0.144 0.2606
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0258 0.144 0.3422
Loa Loa (eye worm) TK/FER protein kinase 0.0686 0.4209 0.7617
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Onchocerca volvulus 0.0428 0.2538 0.6029
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Trichomonas vaginalis protein tyrosine kinase, putative 0.0258 0.144 1
Loa Loa (eye worm) melatonin receptor type 1A 0.004 0.0028 0.0051
Echinococcus granulosus protein tyrosine kinase 0.0258 0.144 0.144
Echinococcus granulosus suppressor of cytokine signaling 6 0.0428 0.2538 0.2538
Echinococcus multilocularis SHC transforming protein 3 0.0428 0.2538 0.6029
Echinococcus granulosus activin receptor type 0.0258 0.144 0.144
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi G protein-coupled receptor F59B2.13 0.004 0.0028 0.0051
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Echinococcus granulosus tyrosine protein kinase Src64B 0.0686 0.4209 0.4209
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Echinococcus granulosus raf serine:threonine protein kinase 0.0258 0.144 0.144
Schistosoma mansoni tensin-related 0.0428 0.2538 0.6029
Brugia malayi SRC-1 0.0686 0.4209 0.7617
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0028 0.0028
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Brugia malayi SH2 domain containing protein 0.0428 0.2538 0.4592
Echinococcus multilocularis integrin linked protein kinase 0.0258 0.144 0.3422
Loa Loa (eye worm) TK/ROR protein kinase 0.0258 0.144 0.2606
Trichomonas vaginalis protein kinase atn1, putative 0.0258 0.144 1
Brugia malayi Dopamine receptor protein 2 0.004 0.0028 0.0051
Brugia malayi ephrin receptor 1 precursor 0.0258 0.144 0.2606
Echinococcus multilocularis G protein coupled receptor 139 0.004 0.0028 0.0067
Echinococcus multilocularis somatostatin receptor 0.004 0.0028 0.0067
Echinococcus granulosus orexin receptor type 2 0.004 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0031 0.0073
Brugia malayi AKH receptor 0.004 0.0028 0.0051
Schistosoma mansoni adapter molecule crk 0.0428 0.2538 0.6029
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0 0.5
Onchocerca volvulus 0.004 0.0028 0.0067
Brugia malayi Tachykinin-like peptides receptor 99D 0.004 0.0028 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0428 0.2538 0.4592
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0428 0.2538 0.2538
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.004 0.0028 0.0051
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0258 0.144 0.144
Loa Loa (eye worm) TK/FER protein kinase 0.0686 0.4209 0.7617
Onchocerca volvulus 0.0428 0.2538 0.6029
Loa Loa (eye worm) SH2 domain-containing protein 0.0428 0.2538 0.4592
Echinococcus multilocularis tyrosine protein kinase Blk 0.0686 0.4209 1
Plasmodium falciparum tyrosine kinase-like protein 0.0258 0.144 0.5
Schistosoma mansoni coup transcription factor 0.004 0.0031 0.0073
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni hypothetical protein 0.0428 0.2538 0.6029
Loa Loa (eye worm) TK protein kinase 0.0258 0.144 0.2606
Loa Loa (eye worm) G-protein coupled receptor 0.004 0.0028 0.0051
Echinococcus granulosus insulin receptor 0.0258 0.144 0.144
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0258 0.144 0.144
Echinococcus granulosus suppressor of cytokine signaling 7 0.0428 0.2538 0.2538
Loa Loa (eye worm) RGC/RGC protein kinase 0.0258 0.144 0.2606
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0031 0.0056
Schistosoma mansoni growth factor receptor-bound protein 0.0428 0.2538 0.6029
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0258 0.144 0.3422
Brugia malayi protein-tyrosine kinase 0.0686 0.4209 0.7617
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.004 0.0028 0.0067
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0031 0.0073
Echinococcus granulosus tyrosine protein kinase Lyn 0.0686 0.4209 0.4209
Echinococcus granulosus SH2 domain containing adapter protein F 0.0428 0.2538 0.2538
Echinococcus granulosus tyrosine protein kinase Src42A 0.0428 0.2538 0.2538
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0258 0.144 0.3422
Loa Loa (eye worm) TK/EPH protein kinase 0.0258 0.144 0.2606
Trichomonas vaginalis AGC family protein kinase 0.0258 0.144 1
Echinococcus multilocularis tyrosine protein kinase pr2 0.0258 0.144 0.3422
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0028 0.0067
Echinococcus multilocularis tyrosine protein kinase csk 0.0258 0.144 0.3422
Loa Loa (eye worm) TK protein kinase 0.0258 0.144 0.2606
Brugia malayi hypothetical protein 0.0428 0.2538 0.4592
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0028 0.0067
Schistosoma mansoni peptide (allatostatin)-like receptor 0.004 0.0028 0.0067
Echinococcus multilocularis g protein coupled receptor 0.004 0.0028 0.0067
Brugia malayi Dopamine receptor 0.004 0.0028 0.0051
Schistosoma mansoni shc transforming protein 0.0428 0.2538 0.6029
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0031 0.0073
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.004 0.0028 0.0051
Schistosoma mansoni alpha-1 adrenergic receptor 0.004 0.0028 0.0067
Schistosoma mansoni neuropeptide f receptor 76f 0.004 0.0028 0.0067
Schistosoma mansoni nck2/grb4 0.0428 0.2538 0.6029
Brugia malayi SH2 domain containing protein 0.0428 0.2538 0.4592
Loa Loa (eye worm) hypothetical protein 0.0428 0.2538 0.4592
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0258 0.144 0.3422
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.004 0.0028 0.0067
Echinococcus multilocularis transfer RNA-Thr 0.0258 0.144 0.3422
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0686 0.4209 1
Schistosoma mansoni thyroid hormone receptor 0.004 0.0031 0.0073
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0686 0.4209 0.4209
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0258 0.144 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0031 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Echinococcus granulosus sex peptide receptor 0.004 0.0028 0.0028
Mycobacterium ulcerans hypothetical protein 0.0036 0 0.5
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus granulosus tyrosine kinase 0.0686 0.4209 0.4209
Mycobacterium leprae conserved hypothetical protein 0.0036 0 0.5
Onchocerca volvulus 0.0428 0.2538 0.6029
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0258 0.144 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0028 0.0067
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0031 0.0031
Brugia malayi hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0031 0.0073
Echinococcus multilocularis g protein coupled receptor 0.004 0.0028 0.0067
Entamoeba histolytica protein kinase, putative 0.0428 0.2538 0.3964
Loa Loa (eye worm) SRC-1 0.0686 0.4209 0.7617
Echinococcus multilocularis FL cytokine receptor 0.0258 0.144 0.3422
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.0889 0.5526 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0258 0.144 0.3422
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0028 0.0067
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0428 0.2538 0.6029
Brugia malayi G protein-coupled receptor 0.004 0.0028 0.0051
Loa Loa (eye worm) neuropeptide F receptor 0.004 0.0028 0.0051
Brugia malayi G-protein coupled receptor 0.004 0.0028 0.0051
Onchocerca volvulus 0.0258 0.144 0.3422
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Loa Loa (eye worm) TK/FER protein kinase 0.0686 0.4209 0.7617
Echinococcus multilocularis g protein coupled receptor 0.004 0.0028 0.0067
Brugia malayi SH2 domain containing protein 0.0686 0.4209 0.7617
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0428 0.2538 0.6029
Loa Loa (eye worm) TK protein kinase 0.0258 0.144 0.2606
Mycobacterium ulcerans beta-lactamase 0.0036 0 0.5
Echinococcus multilocularis tyrosine protein kinase Srms 0.0686 0.4209 1
Brugia malayi STAT protein, DNA binding domain containing protein 0.0428 0.2538 0.4592
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Brugia malayi Protein kinase domain containing protein 0.0258 0.144 0.2606
Echinococcus multilocularis orexin receptor type 2 0.004 0.0028 0.0067
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0258 0.144 1
Onchocerca volvulus 0.0428 0.2538 0.6029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0686 0.4209 1
Loa Loa (eye worm) TK/FER protein kinase 0.0258 0.144 0.2606
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase csk 0.0258 0.144 0.3422
Onchocerca volvulus 0.004 0.0028 0.0067
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0258 0.144 0.144
Brugia malayi hypothetical protein 0.004 0.0028 0.0051
Echinococcus granulosus retinal guanylyl cyclase 2 0.0258 0.144 0.144
Brugia malayi hypothetical protein 0.0686 0.4209 0.7617
Schistosoma mansoni tyrosine kinase 0.0258 0.144 0.3422
Echinococcus multilocularis alpha 1A adrenergic receptor 0.004 0.0028 0.0067
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0031 0.0073
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Brugia malayi hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni neuropeptide F-like receptor 0.004 0.0028 0.0067
Entamoeba histolytica protein kinase, putative 0.0268 0.1507 0.024
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0267 0.1497 0.2709
Brugia malayi Serotonin receptor 0.004 0.0028 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0258 0.144 1
Loa Loa (eye worm) hypothetical protein 0.0258 0.144 0.2606
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus granulosus allatostatin A receptor 0.004 0.0028 0.0028
Brugia malayi hypothetical protein 0.004 0.0028 0.0051
Schistosoma mansoni protein kinase 0.0258 0.144 0.3422
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi RNA, U transporter 1 0.0081 0.0295 0.0534
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0 0.5
Brugia malayi RhoGAP domain containing protein 0.0428 0.2538 0.4592
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0258 0.144 0.144
Brugia malayi Serotonin/octopamine receptor family protein 7 0.004 0.0028 0.0051
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.1744 0.3157
Loa Loa (eye worm) TK/FER protein kinase 0.0686 0.4209 0.7617
Trichomonas vaginalis TK family protein kinase 0.0258 0.144 1
Brugia malayi G-protein coupled receptor 0.004 0.0028 0.0051
Schistosoma mansoni biogenic amine receptor 0.004 0.0028 0.0067
Giardia lamblia Kinase, NEK 0.0258 0.144 0.5
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0031 0.0056
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0428 0.2538 0.3964
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0258 0.144 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Brugia malayi Protein kinase domain containing protein 0.0686 0.4209 0.7617
Echinococcus granulosus fmrfamide receptor 0.004 0.0028 0.0028
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0258 0.144 0.144
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0258 0.144 0.3422
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0056
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Brugia malayi hypothetical protein 0.0258 0.144 0.2606
Onchocerca volvulus 0.0258 0.144 0.3422
Schistosoma mansoni vesicular acetylcholine transporter 0.0267 0.1497 0.3557
Echinococcus granulosus dro:myosuppressin receptor 0.004 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0051
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0031 0.0073
Plasmodium vivax protein kinase, putative 0.0258 0.144 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Trichomonas vaginalis TKL family protein kinase 0.0258 0.144 1
Echinococcus granulosus SH2 motif 0.0428 0.2538 0.2538
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0031 0.0056
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.004 0.0028 0.0028
Brugia malayi hypothetical protein 0.004 0.0028 0.0051
Echinococcus granulosus activated cdc42 kinase 1 0.0258 0.144 0.144
Onchocerca volvulus 0.0686 0.4209 1
Schistosoma mansoni tensin 0.0428 0.2538 0.6029

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.